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<title>18 May, 2021</title>
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<h1 data-aos="fade-down" id="covid-19-sentry">Covid-19 Sentry</h1>
<h1 data-aos="fade-right" data-aos-anchor-placement="top-bottom" id="contents">Contents</h1>
<ul>
<li><a href="#from-preprints">From Preprints</a></li>
<li><a href="#from-clinical-trials">From Clinical Trials</a></li>
<li><a href="#from-pubmed">From PubMed</a></li>
<li><a href="#from-patent-search">From Patent Search</a></li>
</ul>
<h1 data-aos="fade-right" id="from-preprints">From Preprints</h1>
<ul>
<li><strong>Systematic Review and Meta-analysis on COVID-19 Vaccine Hesitancy</strong> -
<div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Background: The presented meta-analysis was developed in response to the publication of several studies addressing COVID-19 vaccines hesitancy. We aimed to identify the proportion of vaccine acceptance and rejection, and factors affecting vaccine hesitancy worldwide especially with the fast emergency approval of vaccines. Methods: Online database search was performed, and relevant studies were included with no language restriction. A meta-analysis was conducted using R software to obtain the random effect model of the pooled prevalence of vaccine acceptance and rejection. Egger regression test was performed to assess publication bias. Quality assessment was assessed using Newcastle-Ottawa Scale quality assessment tool. Results: Thirty-nine out of 12246 articles met the predefined inclusion criteria. All studies were cross-sectional designs. The pooled proportion of COVID-19 vaccine hesitancy was 17% (95% CI: 14-20) while the pooled proportion of COVID-19 vaccine acceptance was 75% (95% CI: 71-79). The vaccine hesitancy and the vaccine acceptance showed high heterogeneity (I 2 =100%). Case fatality ratio and the number of reported cases had significant effect on the vaccine acceptance as the pooled proportion of vaccine acceptance increased by 39.95% (95% CI: 20.1-59.8) for each 1% increase in case fatality (P&lt;0.0001) and decreased by 0.1% (95% CI: -0.2-0.01) for each 1000 reported case of COVID-19, P= 0.0183). Conclusion: Transparency in reporting the number of newly diagnosed COVID-19 cases and deaths is mandatory as these factors are the main determinants of COVID-19 vaccine acceptance.
</p>
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.05.15.21257261v1" target="_blank">Systematic Review and Meta-analysis on COVID-19 Vaccine Hesitancy</a>
</div></li>
<li><strong>Controlling risk of SARS-CoV-2 infection in essential workers of enclosed food manufacturing facilities</strong> -
<div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
The SARS-CoV-2 global pandemic poses significant health risks to workers who are essential to maintaining the food supply chain. Using a quantitative risk assessment model, this study characterized the impact of risk reduction strategies for controlling SARS-CoV-2 transmission (droplet, aerosol, fomite-mediated) among front-line workers in a representative enclosed food manufacturing facility. We simulated: 1) individual and cumulative SARS-CoV-2 infection risks from close contact (droplet and aerosols at 1-3m), aerosol, and fomite-mediated exposures to a susceptible worker following exposure to an infected worker during an 8h-shift; and 2) the relative reduction in SARS-CoV-2 infection risk attributed to infection control interventions (physical distancing, mask use, ventilation, surface disinfection, hand hygiene). Without mitigation measures, the SARS-CoV-2 infection risk was largest for close contact (droplet and aerosol) at 1m (0.96, 95%CI: 0.67-1.0). In comparison, risk associated with fomite (0.26, 95%CI: 0.10-0.56) or aerosol exposure alone (0.05, 95%CI: 0.01-0.13) at 1m distance was substantially lower (73-95%). At 1m, droplet transmission predominated over aerosol and fomite-mediated transmission, however, this changed by 3m, with aerosols comprising the majority of the exposure dose. Increasing physical distancing reduced risk by 84% (1 to 2m) and 91% (1 to 3m). Universal mask use reduced infection risk by 52-88%, depending on mask type. Increasing ventilation (from 0.1 to 2-8 air changes/hour) resulted in risk reductions of 14-54% (1m) and 55-85% (2m). Combining these strategies, together with handwashing and surface disinfection, resulted in &lt;1% infection risk. Current industry SARS-CoV-2 risk reduction strategies, particularly when bundled, provide significant protection to essential food workers.
</p>
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.05.14.21257244v1" target="_blank">Controlling risk of SARS-CoV-2 infection in essential workers of enclosed food manufacturing facilities</a>
</div></li>
<li><strong>Prediction of the effective reproduction number of COVID-19 in Greece. A machine learning approach using Google mobility data.</strong> -
<div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
This paper demonstrates how a short-term prediction of the effective reproduction number (Rt) of COVID-19 in regions of Greece is achieved based on online mobility data. Various machine learning methods are applied to predict Rt and attribute importance analysis is performed to reveal the most important variables that affect the accurate prediction of Rt. Our results are based on an ensemble of diverse Rt methodologies to provide non-precautious and non-indulgent predictions. The model demonstrates robust results and the methodology overall represents a promising approach towards COVID-19 outbreak prediction. This paper can help health related authorities when deciding non-nosocomial interventions to prevent the spread of COVID-19.
</p>
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.05.14.21257209v1" target="_blank">Prediction of the effective reproduction number of COVID-19 in Greece. A machine learning approach using Google mobility data.</a>
</div></li>
<li><strong>Non-differential risk of SARS-CoV-2 infection for members of polling stations on Catalan parliament voting day.</strong> -
<div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
We aimed to assess the risk of SARS-CoV-2 infection for polling station members during the Catalan elections in February 2021. We compared the incidence 14 days after the elections between a cohort of polling station members (N= 18,304) and a control cohort paired by age, sex and place of residence. A total of 37 COVID-19 cases (0.2%) were confirmed in the members of the polling stations and 43 (0.23%) in the control group (p-value 0.576). Our study suggests that there was no greater risk of infection for the members of the polling stations.
</p>
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.05.13.21257143v1" target="_blank">Non-differential risk of SARS-CoV-2 infection for members of polling stations on Catalan parliament voting day.</a>
</div></li>
<li><strong>A novel deterministic epidemic model considering mass vaccination and lockdown against Covid-19 spread in Israel: Numerical study</strong> -
<div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Why public health intervention by Israel government against COVID-19 spread has been successful while the most countries in the world is still coping with it? To give the answer, a simple numerical epidemic model is prepared to simulate an entire trend of various infection related variables considering vaccination campaign and simultaneous lockdown. The model is an extension of the deterministic physical model ATLM previously published by the authors that aims to predict an entire trend of variables in a single epidemic. The time series data of both vaccine dose ratio and lockdown period are employed in the model. Predictions have been compared with observed data in terms of daily new cases, isolated people, infectious at large and effective reproductive number and the model is verified. Moreover, parameter survey calculations for several scenarios have clarified a synergy effect of vaccination and lockdown have existed. In particular, it is suggested the key element of Israel success lies in a high dose rate of vaccination that avoids the onset of the rebound of daily new cases on the rescission of the lockdown.
</p>
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.05.15.21257264v1" target="_blank">A novel deterministic epidemic model considering mass vaccination and lockdown against Covid-19 spread in Israel: Numerical study</a>
</div></li>
<li><strong>Occupation, Work-Related Contact, and SARS-CoV-2 Anti-Nucleocapsid Serological Status: Findings from the Virus Watch prospective cohort study</strong> -
<div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Background: Workers differ in their risk of acquiring SARS-CoV-2 infection according to their occupation; however, few studies have been able to control for multiple confounders or investigate the work-related factors that drive differences in occupational risk. Using data from the Virus Watch community cohort study in England and Wales, we set out to estimate the total effect of occupation on SARS-CoV-2 serological status, whether this is mediated by frequency of close contact within the workplace, and how exposure to poorly ventilated workplaces varied across occupations. Methods: We used data from a sub-cohort (n =3761) of adults (≥18) tested for SARS-CoV-2 anti-nucleocapsid antibodies between 01 February-28 April 2021 and responded to a questionnaire about work during the pandemic. Anti-nucleocapsid antibodies were used as a proxy of prior natural infection with COVID-19. We used logistic decomposition to estimate the total and direct effect of occupation and indirect effect of workplace contact frequency on odds of seropositivity, adjusting for age, sex, household income and region. We investigated the relationship between occupation and exposure to poorly-ventilated workplace environments using ordinal logistic regression. Results: Seropositivity was 16.0% (113/707) amongst workers with daily close contact, compared to 12.9% (120/933) for those with intermediate-frequency contact and 9.6% (203/2121) for those with no work-related close contact. Healthcare (OR= 2.14, 95% CI 1.47,3.12), indoor trade, process and plant (2.09, 1.31,3.33), leisure and personal service (1.96, 1.004,3.84), and transport and mobile machine (2.17, 1.12,4.18) workers had elevated total odds of SARS-CoV-2 seropositivity compared to other professional and associate occupations. Frequency of workplace contact accounted for a variable part of the increased odds in different occupational groups (OR range 1.04 [1.0004,1.07] - 1.22 [1.07, 1.38]). Healthcare workers and indoor trades and process plant workers continued to have raised odds of infection after accounting for work-related contact, and also had had greater odds of frequent exposure to poorly-ventilated workplaces (respectively 2.15 [1.66, 2.79] and (1.51, [1.12, 2.04]). Discussion: Marked variations in occupational odds of seropositivity remain after accounting for age, sex, region, and household income. Close contact in the workplace appears to contribute substantially to this variation. Reducing frequency of workplace contact is a critical part of COVID-19 control measures.
</p>
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.05.13.21257161v1" target="_blank">Occupation, Work-Related Contact, and SARS-CoV-2 Anti-Nucleocapsid Serological Status: Findings from the Virus Watch prospective cohort study</a>
</div></li>
<li><strong>A Time Series Analysis and Forecast of COVID-19 Healthcare Disparity</strong> -
<div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
This work focuses on a time series analysis and forecast of COVID 19. Decision makers and medical providers will find the work useful in improving cares to the disadvantaged demography, reduce the spread of the coronavirus and improve mitigation strategy to combat the impact of the disease. Our anatomy of COVID cases spans March 2020 to December 2020. COVID 19 forecasting cases and deaths models were built for the total population and blacks in eight states in the USA. State with medium to large populations of blacks were considered for the experiment. We defined COVID-19 Health Care Disparity (CHCD) as the difference between the percentage of Black Cases to Total Cases and Black Deaths to Total Deaths within a period. We hypothesized that a disparity exists if the ratio of black cases to the total COVID-19 population in a state, is less than the ratio of black deaths to the total deaths in the same state. The outcome of our experiment shows that there exists COVID-19 Health Care Disparity in the black community. Furthermore, all things being equal, our forecast suggests that the COVID-19 Health Care Disparities will continue at least till the end of the first quarter of 2021.
</p>
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.05.13.21257189v1" target="_blank">A Time Series Analysis and Forecast of COVID-19 Healthcare Disparity</a>
</div></li>
<li><strong>Combined association of obesity and other cardiometabolic diseases with severe COVID-19 outcomes: a nationwide cross-sectional study of 21,773 Brazilian adult and elderly inpatients</strong> -
<div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Objective: To investigate the combined association of obesity, diabetes mellitus (DM), and cardiovascular disease (CVD) with severe COVID-19 outcomes in adult and elderly inpatients. Design: Cross-sectional study based on registry data from Brazil9s influenza surveillance system. Setting: Public and private hospitals across Brazil. Participants: Eligible population included 21,942 inpatients aged 20 years or older with positive RT-PCR test for SARS-CoV-2 until Jun 9th, 2020. Main outcome measures: Severe COVID-19 outcomes were non-invasive and invasive mechanical ventilation use, ICU admission, and death. Multivariate analyses were conducted separately for adults (20-59 years) and elders (&gt;=60 years) to test the combined association of obesity (without and with DM and/or CVD) and degrees of obesity with each outcome. Results: A sample of 8,848 adults and 12,925 elders were included. Among adults, obesity with DM and/or CVD showed higher prevalence of invasive (PR 3.76, 95%CI 2.82-5.01) and non-invasive mechanical ventilation use (2.06, 1.58-2.69), ICU admission (1.60, 1.40-1.83), and death (1.79, 1.45-2.21) compared with the group without obesity, DM, and CVD. In elders, obesity alone (without DM and CVD) had the highest prevalence of ICU admission (1.40, 1.07-1.82) and death (1.67, 1.00-2.80). In both age groups, obesity alone and combined with DM and/or CVD showed higher prevalence in all outcomes than DM and/or CVD. A dose-response association was observed between obesity and death in adults: class I 1.32 (1.05-1.66), class II 1.41 (1.06-1.87), and class III 1.77 (1.35-2.33). Conclusions: The combined association of obesity, diabetes, and/or CVD with severe COVID-19 outcomes may be stronger in adults than in elders. Obesity alone and combined with DM and/or CVD had more impact on the risk of COVID-19 severity than DM and/or CVD in both age groups. The study also supports an independent relationship of obesity with severe outcomes, including a dose-response association between degrees of obesity and death in adults. These findings suggest important implications for the clinical care of patients with obesity and severe COVID-19 and support the inclusion of people with obesity in the high-risk and vaccine priority groups for protection from SARS-CoV-2.
</p>
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.05.14.21257204v1" target="_blank">Combined association of obesity and other cardiometabolic diseases with severe COVID-19 outcomes: a nationwide cross-sectional study of 21,773 Brazilian adult and elderly inpatients</a>
</div></li>
<li><strong>Racism, Posttraumatic Stress Symptoms, and Racial Disparity in the U.S. COVID-19 Syndemic</strong> -
<div>
The COVID-19 syndemic, with a disproportionately higher adverse impact on communities of color (i.e., COVID-19 infection and death), will likely exacerbate the existing health disparities in trauma-related symptoms between people of color (POC) and White Americans. However, no studies have examined the racial disparities in posttraumatic stress symptoms (PTSS) during COVID-19. Grounded in ecological theory and racial trauma framework, we investigated rates of racial disparities in PTSS and three possible mechanisms, 1) COVID stress, 2) direct racism, and 3) indirect racism, for these discrepancies using a large U.S. national sample (N = 2,019). Results indicated that POC reported higher levels of PTSS than White Americans (d =.21). The PTSS racial disparity was accounted more by direct and indirect racism than by the COVID-19-specific stressors, after controlling for age, gender, education, income, parent status, adverse childhood experiences (ACEs), and intimate partner violence (IPV). Additional fine-grained analyses for Hispanic/Latinx Americans (n = 283), Black/African Americans (n = 279), and Asian American and Pacific Islanders (n = 123) by and large corroborated the above findings. Our findings highlighted the deleterious impact of the ongoing racism pandemic on the POC community as a public health crisis in addition to the COVID-19 pandemic.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://psyarxiv.com/rc2ns/" target="_blank">Racism, Posttraumatic Stress Symptoms, and Racial Disparity in the U.S. COVID-19 Syndemic</a>
</div></li>
<li><strong>The impact of the COVID-19 pandemic on the employment situation and financial well-being of families with children in Austria: Evidence from the first ten months of the crisis</strong> -
<div>
Objective: This study investigates the impact of the COVID-19 pandemic on the employment situation of parents and in turn on the subjective financial well-being of families with children in Austria. Background: The pandemic had strong repercussions on the Austrian labour market. The short-time work (STW) programme covered a third of employees in the first half of 2020 and helped to maintain employment levels. We provide evidence on how an unprecedented labour market crisis of this sort and in particular the exceptionally wide use of STW had affected the (gendered) employment situation of parents and the financial well-being of different types of families. Method: The study draws on representative panel survey data that cover 905 families with underage children. The data include information on the employment situation and financial well-being of single and cohabiting parents before the onset of the crisis, three months and ten months after its onset. Results: In contrast to other countries, mothers were not more strongly affected by the labour market crisis of 2020 than childless women or fathers. About a third of couples with underage children experienced income losses. Despite the wide use of STW and government support to families, the share of families in financial difficulties has substantially increased, especially among those with many children and single parents, many of who were at risk of poverty already before the crisis. Conclusion: Substantial shares of dual-earner families that had low poverty risks before the crisis were in financial difficulties in 2020. Potential spill-over effects of financial shocks on children are discussed.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/preprints/socarxiv/r7ugz/" target="_blank">The impact of the COVID-19 pandemic on the employment situation and financial well-being of families with children in Austria: Evidence from the first ten months of the crisis</a>
</div></li>
<li><strong>“How do we do this at a distance?!” A descriptive study of remote undergraduate research programs during COVID-19</strong> -
<div>
The COVID-19 pandemic shut down undergraduate research programs across the U.S. Twenty-three sites offered remote undergraduate research programs in the life sciences during summer 2020. Given the unprecedented offering of remote research experiences, we carried out a study to describe and evaluate these programs. Using structured templates, we documented how programs were designed and implemented, including who participated. Through focus groups and surveys, we identified programmatic strengths and shortcomings as well as recommendations for improvements from the perspectives of participating students. Strengths included the quality of mentorship, opportunities for learning and professional development, and development of a sense of community. Weaknesses included limited cohort building, challenges with insufficient structure, and issues with technology. Although all programs had one or more activities related to diversity, equity, inclusion, and justice, these topics were largely absent from student reports even though programs coincided with a peak in national consciousness about racial inequities and structural racism. Our results provide evidence for designing remote REUs that are experienced favorably by students. Our results also indicate that remote REUs are sufficiently positive to further investigate their affordances and constraints, including the potential to scale up offerings, with minimal concern about disenfranchising students.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.05.17.443632v1" target="_blank">“How do we do this at a distance?!” A descriptive study of remote undergraduate research programs during COVID-19</a>
</div></li>
<li><strong>Targeted redesign of suramin analogs for novel antimicrobial lead development</strong> -
<div>
The emergence of new viral infections and drug resistant bacteria urgently necessitates expedient therapeutic development. Repurposing and redesign of existing drugs against different targets is one potential way in which to accelerate this process. Suramin was initially developed as a successful anti-parasitic drug, but has also shown promising antiviral and antibacterial activities. However, due to its high conformational flexibility and negative charge, suramin is considered quite promiscuous towards positively charged sites within nucleic acid binding proteins. Although some suramin analogs have been developed against specific targets, only limited structure activity relationship (SAR) studies were performed, and virtual screening has yet to be used to identify more specific inhibitor(s) based on its scaffold. Using available structures, we investigated suramins target diversity, confirming that suramin preferentially binds to protein pockets which are both positively charged and enriched in aromatic or leucine residues. Further, suramins high conformational flexibility allows adaptation to structurally diverse binding surfaces. From this platform, we developed a framework for structure- and docking-guided elaboration of suramin analog scaffolds using virtual screening of suramin and heparin analogs against a panel of diverse therapeutically relevant viral and bacterial protein targets. Use of this new framework to design potentially specific suramin analogs is exemplified using the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) and nucleocapsid protein, identifying leads that might inhibit a wide range of coronaviruses. The approach presented here establishes a new computational framework for designing suramin analogs against different bacterial and viral targets and repurposing existing drugs for more specific inhibitory activity.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.05.17.444489v1" target="_blank">Targeted redesign of suramin analogs for novel antimicrobial lead development</a>
</div></li>
<li><strong>High level production and characterization of truncated human angiotensin converting enzyme 2 in Nicotiana benthamiana plant as a potential therapeutic target in COVID-19</strong> -
<div>
The COVID-19 pandemic, which is caused by SARS-CoV-2 has rapidly spread to more than 222 countries and has put global public health at high risk. The world urgently needs safe, a cost-effective SARS-CoV-2 coronavirus vaccine, therapeutic and antiviral drugs to combat the COVID-19. Angiotensin-converting enzyme 2 (ACE2), as a key receptor for SARS-CoV-2 infections, has been proposed as a potential therapeutic target in COVID-19 patients. In this study, we report high level production (about ~0.75 g /kg leaf biomass) of glycosylated and non-glycosylated forms of recombinant human truncated ACE2 in Nicotiana benthamiana plant. The plant produced recombinant human truncated ACE2s successfully bind to the SARC-CoV-2 spike protein, but deglycosylated ACE2 binds more strongly than the glycosylated counterpart. Importantly, both deglycosylated and glycosylated forms of AEC2 stable at elevated temperatures for prolonged periods and demonstrated strong anti-SARS-CoV-2 activity in vitro. The IC50 values of glycosylated and deglycosylated AEC2 were 0.4 and 24 g/ml, respectively, for the pre-entry infection, when incubated with 100TCID50 of SARS-CoV-2. Thus, plant produced truncated ACE2s are promising cost-effective and safe candidate as a potential therapeutic targets in the treatment of COVID-19 patients.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.05.17.444533v1" target="_blank">High level production and characterization of truncated human angiotensin converting enzyme 2 in Nicotiana benthamiana plant as a potential therapeutic target in COVID-19</a>
</div></li>
<li><strong>Sociodemographic inequality in COVID-19 vaccination coverage amongst elderly adults in England: a national linked data study</strong> -
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Objective: To examine inequalities in COVID-19 vaccination rates amongst elderly adults in England Design: Cohort study Setting: People living in private households and communal establishments in England Participants: 6,829,643 adults aged 70 years or above (mean 78.7 years, 55.2% female) who were alive on 15 March 2021. Main outcome measures: Having received the first dose of a vaccine against COVID-19 by 15 March 2021. We calculated vaccination rates and estimated unadjusted and adjusted odds ratios using logistic regression models. Results: By 15 March 2021, 93.2% of people living in England aged 70 years and over had received at least one dose of a COVID-19 vaccine. While vaccination rates differed across all factors considered apart from sex, the greatest disparities were seen between ethnic and religious groups. The lowest rates were in people of Black African and Black Caribbean ethnic backgrounds, where only 67.2% and 73.9% had received a vaccine, with adjusted odds of not being vaccinated at 5.01 (95% CI 4.86 - 5.16) and 4.85 (4.75 - 4.96) times greater than the White British group. The proportion of individuals self-identifying as Muslim and Buddhist who had received a vaccine was 79.1% and 84.1%, respectively. Older age, greater area deprivation, less advantaged socio-economic position (proxied by living in a rented home), being disabled and living either alone or in a multi-generational household were also associated with higher odds of not having received the vaccine. Conclusion: People disproportionately affected seem most hesitant to COVID-19 vaccinations. Policy Interventions to improve these disparities are urgently needed.
</p>
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.05.13.21257146v1" target="_blank">Sociodemographic inequality in COVID-19 vaccination coverage amongst elderly adults in England: a national linked data study</a>
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<li>**HLA-B*15:01 is associated with asymptomatic SARS-CoV-2 infection** -
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Background. Evidence has shown that a large proportion of SARS-CoV-2 infected individuals do not experience symptomatic disease. Owing to its critical role in immune response, we hypothesized that variation in the human leukocyte antigen (HLA) loci may underly asymptomatic infection. Methods. We enrolled 29,947 individuals registered in the National Marrow Donor Program for whom high-resolution HLA genotyping data were available in a smartphone-based study designed to track COVID-19 symptoms and outcomes. Among 21,893 individuals who completed the baseline survey, our discovery (N=640) and replication (N=788) cohorts were comprised of self-identified White subjects who reported a positive test result for SARS-CoV-2. We tested for association of five HLA loci (HLA-A, -B, -C, -DRB1, -DQB1) with asymptomatic vs. symptomatic infection. Results. HLA-B<em>15:01 was significantly increased in asymptomatic individuals in the discovery cohort compared to symptomatic (OR = 2.45; 95%CI 1.38-4.24, p = 0.0016, pcorr = 0.048), and we reproduced this association in the replication cohort (OR= 2.32; 95%CI = 1.10-4.43, p = 0.017). We found robust association of HLA-B</em>15:01 in the combined dataset (OR=2.40 95% CI = 1.54-3.64; p = 5.67 x10-5) and observed that homozygosity of this allele increases more than eight times the chance of remaining asymptomatic after SARS-CoV-2 infection (OR = 8.58, 95%CI = 1.74-34.43, p = 0.003). Finally, we demonstrated the association of HLA-B<em>15:01 with asymptomatic SARS-Cov-2 infection is enhanced by the presence of HLA-DRB1</em>04:01 Conclusion. HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance.
</p>
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<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.05.13.21257065v1" target="_blank">HLA-B*15:01 is associated with asymptomatic SARS-CoV-2 infection</a>
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<h1 data-aos="fade-right" id="from-clinical-trials">From Clinical Trials</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Recombinant Hyperimmune Polyclonal Antibody (GIGA-2050) in COVID-19 Patients</strong> - <b>Condition</b>:   COVID-19<br/><b>Intervention</b>:   Drug: GIGA-2050<br/><b>Sponsor</b>:   GigaGen, Inc.<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Drug: RO7496998;   Drug: Placebo<br/><b>Sponsors</b>:   Atea Pharmaceuticals, Inc.;   Hoffmann-La Roche<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Role of High Dose Co-trimoxazole in Severe Covid-19 Patients</strong> - <b>Condition</b>:   COVID-19 Pneumonia<br/><b>Interventions</b>:   Drug: Co-trimoxazole;   Drug: Placebo<br/><b>Sponsor</b>:   Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Effect of Vitamin D Supplementation on COVID-19 Recovery</strong> - <b>Condition</b>:   Covid19<br/><b>Interventions</b>:   Drug: Vit-D 0.2 MG/ML Oral Solution [Calcidol];   Drug: Physiological Irrigating Solution<br/><b>Sponsors</b>:   University of Monastir;   Loussaief Chawki;   Nissaf Ben Alaya;   Cyrine Ben Nasrallah;   Manel Ben Belgacem;   Hela Abroug;   Imen Zemni;   Manel Ben fredj;   Wafa Dhouib<br/><b>Completed</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Study to Evaluate the Safety and Effect of STC3141 Continuous Infusion in Subjects With Severe Corona Virus Disease 2019COVID-19Pneumonia</strong> - <b>Condition</b>:   Severe COVID-19 Pneumonia<br/><b>Intervention</b>:   Drug: STC3141<br/><b>Sponsors</b>:   Grand Medical Pty Ltd.;   Trium Clinical Consulting<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>tDCS for Post COVID-19 Fatigue</strong> - <b>Condition</b>:   Post Covid-19 Patients<br/><b>Intervention</b>:   Device: Transcranial Direct Current Stimulation<br/><b>Sponsor</b>:   Thorsten Rudroff<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Phase 2 Study of APX-115 in Hospitalized Patients With Confirmed Mild to Moderate COVID-19.</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Drug: APX-115;   Drug: Placebo<br/><b>Sponsors</b>:   Aptabio Therapeutics, Inc.;   Covance<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Leveraging CHWs to Improve COVID-19 Testing and Mitigation Among CJIs Accessing a Corrections-focused CBO</strong> - <b>Condition</b>:   Covid19<br/><b>Intervention</b>:   Behavioral: Onsite Point-of-care<br/><b>Sponsors</b>:   Montefiore Medical Center;   The Fortune Society;   University of Bristol<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Breathing Effort in Covid-19 Pneumonia: Effects of Positive Pressure, Inspired Oxygen Fraction and Decubitus</strong> - <b>Condition</b>:   COVID-19 Pneumonia<br/><b>Intervention</b>:   Device: Esophageal catheter<br/><b>Sponsor</b>:   San Luigi Gonzaga Hospital<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Convalescent Plasma as Adjunct Therapy for COVID-19</strong> - <b>Condition</b>:   COVID-19<br/><b>Intervention</b>:   Biological: Convalescent plasma treatment<br/><b>Sponsors</b>:   National Institute of Health Research and Development, Ministry of Health Republic of Indonesia;   Indonesian Red Cross;   Eijkman Institute for Molecular Biology<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Anti COVID 19 Intravenous Immunoglobulin (C-IVIG) Therapy for Severe COVID-19 Patients</strong> - <b>Condition</b>:   Covid19<br/><b>Intervention</b>:   Biological: Anti COVID 19 Intravenous Immunoglobulin (C-IVIG)<br/><b>Sponsors</b>:   Dow University of Health Sciences;   Higher Education Commission (Pakistan)<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Global Phase III Clinical Trial of Recombinant COVID-19 Vaccine (Sf9 Cells)</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Biological: Recombinant COVID-19 vaccine (Sf9 cells);   Other: Placebo control<br/><b>Sponsors</b>:   Jiangsu Province Centers for Disease Control and Prevention;   WestVac Biopharma Co., Ltd.;   West China Hospital<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>ACTIV-6: COVID-19 Study of Repurposed Medications</strong> - <b>Condition</b>:   Covid19<br/><b>Intervention</b>:   Drug: Ivermectin Tablets<br/><b>Sponsors</b>:   Susanna Naggie, MD;   National Center for Advancing Translational Science (NCATS);   Vanderbilt University Medical Center<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Effectiveness of Remedesvir in COVID-19 Patients Presenting at Mayo Hospital Lahore</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Drug: Remdesivir;   Drug: Conventional<br/><b>Sponsor</b>:   King Edward Medical University<br/><b>Completed</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Symprove (Probiotic) as an add-on to COVID-19 Management</strong> - <b>Condition</b>:   Covid19<br/><b>Interventions</b>:   Other: Symprove (probiotic);   Other: Placebo<br/><b>Sponsor</b>:   Kings College Hospital NHS Trust<br/><b>Not yet recruiting</b></p></li>
</ul>
<h1 data-aos="fade-right" id="from-pubmed">From PubMed</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Review of antiviral peptides for use against zoonotic and selected non-zoonotic viruses</strong> - Viruses remain one of the leading causes of animal and human disease. Some animal viral infections spread sporadically to human populations, posing a serious health risk. Particularly the emerging viral zoonotic diseases such as the novel, zoonotic coronavirus represent an actual challenge for the scientific and medical community. Besides human health risks, some animal viral infections, although still not zoonotic, represent important economic loses to the livestock industry. Viral infections…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Convenient and Biosafe Replicon with Accessory Genes of SARS-CoV-2 and Its Potential Application in Antiviral Drug Discovery</strong> - SARS-CoV-2 causes the pandemic of COVID-19 and no effective drugs for this disease are available thus far. Due to the high infectivity and pathogenicity of this virus, all studies on the live virus are strictly confined in the biosafety level 3 (BSL3) laboratory but this would hinder the basic research and antiviral drug development of SARS-CoV-2 because the BSL3 facility is not commonly available and the work in the containment is costly and laborious. In this study, we constructed a reverse…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A large-scale computational screen identifies strong potential inhibitors for disrupting SARS-CoV-2 S-protein and human ACE2 interaction</strong> - SARS-CoV-2 has infected millions of individuals across the globe and has killed over 2.7 million people. Even though vaccines against this virus have recently been introduced, the antibody generated in the process has been reported to decline quickly. This can reduce the efficacy of vaccines over time and can result in re-infections. Thus, drugs that are effective against COVID-19 can provide a second line of defence and can prevent occurrence of the severe form of the disease. The interaction…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Computational basis of SARS-CoV 2 main protease inhibition: an insight from molecular dynamics simulation based findings</strong> - The coronavirus disease 2019 (COVID-19) pandemic is caused by newly discovered severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). One of the striking targets amongst all the proteins in coronavirus is the main protease (M^(pro)), as it plays vital biological roles in replication and maturation of the virus, and hence the potential target. The aim of this study is to repurpose the Food and Drug Administration (FDA) approved molecules via computer-aided drug designing against M^(pro)…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Complement inhibition in severe COVID-19 - Blocking C5a seems to be key</strong> - No abstract</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Computational Identification of a Putative Allosteric Binding Pocket in TMPRSS2</strong> - Camostat, nafamostat, and bromhexine are inhibitors of the transmembrane serine protease TMPRSS2. The inhibition of TMPRSS2 has been shown to prevent the viral infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other viruses. However, while camostat and nafamostat inhibit TMPRSS2 by forming a covalent adduct, the mode of action of bromhexine remains unclear. TMPRSS2 is autocatalytically activated from its inactive form, zymogen, through a proteolytic cleavage that…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Pomegranate Peel Extract as an Inhibitor of SARS-CoV-2 Spike Binding to Human ACE2 Receptor (in vitro): A Promising Source of Novel Antiviral Drugs</strong> - Plant extracts are rich in bioactive compounds, such as polyphenols, sesquiterpenes, and triterpenes, which potentially have antiviral activities. As a consequence of the coronavirus disease 2019 pandemic, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus, thousands of scientists have been working tirelessly trying to understand the biology of this new virus and the disease pathophysiology, with the main goal of discovering effective preventive treatments and…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Design of advanced siRNA therapeutics for the treatment of COVID-19</strong> - COVID-19 is a newly emerged viral disease that is currently affecting the whole globe. A variety of therapeutic approaches are underway to block the SARS-CoV-2 virus. Among these methods, siRNAs could be a safe and specific option, as they have been tested against other viruses. siRNAs are a class of inhibitor RNAs that act promisingly as mRNA expression blockers and they can be designed to interfere with viral mRNA to block virus replication. In order to do this, we designed and evaluated the…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Nucleocapsid and Spike Proteins of SARS-CoV-2 Drive Neutrophil Extracellular Trap Formation</strong> - Patients with severe coronavirus disease 2019 (COVID-19) demonstrate dysregulated immune responses including exacerbated neutrophil functions. Massive neutrophil infiltrations accompanying neutrophil extracellular trap (NET) formations are also observed in patients with severe COVID-19. However, the mechanism underlying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced NET formation has not yet been elucidated. Here we show that 2 viral proteins encoded by SARS-CoV-2, the…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Cardiac TdP risk stratification modelling of anti-infective compounds including chloroquine and hydroxychloroquine</strong> - Hydroxychloroquine (HCQ), the hydroxyl derivative of chloroquine (CQ), is widely used in the treatment of rheumatological conditions (systemic lupus erythematosus, rheumatoid arthritis) and is being studied for the treatment and prevention of COVID-19. Here, we investigate through mathematical modelling the safety profile of HCQ, CQ and other QT-prolonging anti-infective agents to determine their risk categories for Torsade de Pointes (TdP) arrhythmia. We performed safety modelling with…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A SCID mouse-human lung xenograft model of SARS-CoV-2 infection</strong> - SARS-CoV-2 infection, which is responsible for the current COVID-19 pandemic, can cause life-threatening pneumonia, respiratory failure and even death. Characterizing SARS-CoV-2 pathogenesis in primary human target cells and tissues is crucial for developing vaccines and therapeutics. However, given the limited access to clinical samples from COVID-19 patients, there is a pressing need for in vitro/in vivo models to investigate authentic SARS-CoV-2 infection in primary human lung cells or…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Mini-Factor H Modulates Complement-Dependent IL-6 and IL-10 Release in an Immune Cell Culture (PBMC) Model: Potential Benefits Against Cytokine Storm</strong> - Cytokine storm (CS), an excessive release of proinflammatory cytokines upon overactivation of the innate immune system, came recently to the focus of interest because of its role in the life-threatening consequences of certain immune therapies and viral diseases, including CAR-T cell therapy and Covid-19. Because complement activation with subsequent anaphylatoxin release is in the core of innate immune stimulation, studying the relationship between complement activation and cytokine release in…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Cytokine Storm: The Primary Determinant for the Pathophysiological Evolution of COVID-19 Deterioration</strong> - The coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an ongoing major threat to global health and has posed significant challenges for the treatment of severely ill COVID-19 patients. Several studies have reported that cytokine storms are an important cause of disease deterioration and death in COVID-19 patients. Consequently, it is important to understand the specific pathophysiological processes underlying how…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Mefloquine, a Potent Anti-severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Drug as an Entry Inhibitor in vitro</strong> - Coronavirus disease 2019 (COVID-19) has caused serious public health, social, and economic damage worldwide and effective drugs that prevent or cure COVID-19 are urgently needed. Approved drugs including Hydroxychloroquine, Remdesivir or Interferon were reported to inhibit the infection or propagation of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), however, their clinical efficacies have not yet been well demonstrated. To identify drugs with higher antiviral potency, we…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Psychological Predictors of Precautionary Behaviors in Response to COVID-19: A Structural Model</strong> - The first lines of defense during an epidemic are behavioral interventions, including stay-at-home measures or precautionary health training, aimed at reducing contact and disease transmission. Examining the psychosocial variables that may lead to greater adoption of such precautionary behaviors is critical. The present study examines predictors of precautionary practices against coronavirus disease 2019 (COVID-19) in 709 Mexican participants from 24 states. The study was conducted via online…</p></li>
</ul>
<h1 data-aos="fade-right" id="from-patent-search">From Patent Search</h1>
<ul>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>IMPROVEMENTS RELATED TO PARTICLE, INCLUDING SARS-CoV-2, DETECTION AND METHODS THEREFOR</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU323295937">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A COMPREHENSIVE DISINFECTION SYSTEM DURING PANDEMIC FOR PERSONAL ITEMS AND PROTECTIVE EQUIPMENT (PPE) TO SAFEGUARD PEOPLE</strong> - The current Covid-19 pandemic has led to an enormous demand for gadgets / objects for personal protection. To prevent the spread of virus, it is important to disinfect commonly touched objects. One of the ways suggested is to use a personal UV-C disinfecting box that is “efficient and effective in deactivating the COVID-19 virus. The present model has implemented the use of a UV transparent material (fused silica quartz glass tubes) as the medium of support for the objects to be disinfected to increase the effectiveness of disinfection without compromising the load bearing capacity. Aluminum foil, a UV reflecting material, was used as the inner lining of the box for effective utilization of the UVC light emitted by the UVC lamps. Care has been taken to prevent leakage of UVC radiation out of the system. COVID-19 virus can be inactivated in 5 minutes by UVC irradiation in this disinfection box - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=IN322882412">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>UBIQUITOUS COMPUTING SYSTEM FOR MENTAL HEALTH MONITORING OF PERSON DURING THE PANDEMIC OF COVID-19</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU323295498">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>USE OF IMINOSUGAR COMPOUND IN PREPARATION OF ANTI-SARS-COV-2 VIRUS DRUG</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU322897928">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>逆转录酶突变体及其应用</strong> - 本发明提供一种MMLV逆转录酶突变体在野生型MMLV逆转录酶氨基酸序列如SEQ ID No.1序列所示中进行七个氨基酸位点的突变氨基酸突变位点为R205HV288TL304KG525DS526DE531GE574G。该突变体可以降低MMLV逆转录酶对Taq DNA聚合酶的抑制作用大大提高了一步法RTqPCR的灵敏度。 - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=CN323494119">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Compositions and methods for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU321590214">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>用于检测新型冠状病毒的试纸和试剂盒</strong> - 本发明涉及生物技术和免疫检测技术领域具体涉及一种用于检测新型冠状病毒的试纸和试剂盒。所述试纸或试剂盒含有抗体1和/或抗体2所述抗体1的重、轻链可变区的氨基酸序列分别如SEQ ID NO:12所示所述抗体2的重、轻链可变区的氨基酸序列分别如SEQ ID NO:34所示。本发明对于大批量的新型冠状病毒样本包括新型冠状病毒突变英国、南非与非突变株的人血清、鼻咽拭子等样本的检测有普遍检测意义避免突变株的漏检。 - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=CN322953478">link</a></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Fahrgastleitsystem und Verfahren zum Leiten von Fahrgästen</strong> -
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
</p><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">Die Erfindung betrifft ein Fahrgastleitsystem zum Leiten von mit einem Fahrzeug (1) mit wenigstens zwei Türen (2.L, 2.R) transportieren Fahrgästen (3), mit wenigstens einem Sensor (4) zur Überwachung der Fahrgäste (3), wenigstens einem Anzeigemittel (5) zur Ausgabe von Leitinformationen, wenigstens einem Aktor zum Öffnen oder Verriegeln einer Tür (2.L, 2.R) und wenigstens einer Recheneinheit (7). Das erfindungsgemäße Fahrgastleitsystem ist dadurch gekennzeichnet, dass die Recheneinheit (7) dazu eingerichtet ist durch Auswertung vom wenigstens einen Sensor (4) erzeugter Sensordaten zu erkennen an welcher Tür (2.L, 2.R) des Fahrzeugs (1) Fahrgäste (3) ein- und/oder aussteigen möchten und wenigstens eine Tür (2.L, 2.R) für einen Ausstieg festzulegen und/oder wenigstens eine Tür (2.L, 2.R) für einen Einstieg festzulegen, sodass eine Anzahl an Begegnungen von sich durch das Fahrzeug (1) bewegender Fahrgäste (3) und/oder aus dem Fahrzeug (1) aussteigenden und/oder in das Fahrzeug (1) einsteigenden Fahrgästen (3) minimiert wird.</p></li>
</ul>
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=DE323289145">link</a></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Vorrichtung zum Desinfizieren, der Körperpflege oder dergleichen</strong> -
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
</p><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">Vorrichtung zum Desinfizieren, der Körperpflege oder dergleichen mittels einer flüssigen oder cremigen Substanz (20), dadurch gekennzeichnet, dass die Vorrichtung mit einem elektrisch betriebenen Erinnerungs-Modul und einem Vorratsbehälter (10) für die Substanz (20) versehen ist, die Substanz (20) in dosierter Menge zur Ausgabeöffnung (9) gefördert wird und die Vorrichtung dazu geeignet ist, am Körper oder der Kleidung einer Person getragen zu werden.</p></li>
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=DE323289850">link</a></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Gebrauchter Schnellteststreifen als Probenmaterial für eine Nachtestung</strong> -
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
</p><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">Die Erfindung betrifft ein Verfahren zur laborbasierten Überprüfung und/oder weiteren Ausdifferenzierung einer im Schnelltestverfahren erhaltenen Diagnose einer Infektionskrankheit, wobei im Rahmen des Schnelltestverfahrens eine flüssige Patientenprobe auf ein Objekt aus einem porösen Material aufgetragen wird und wobei dieses Objekt nach Trocknung der flüssigen Patientenprobe an das diagnostische Labor übermittelt wird. Im Labor werden dann die eingetrockneten Probenreste aus dem porösen Material ausgelöst und analysiert.</p></li>
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<li><a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=DE323289151">link</a></li>
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<h1 data-aos="fade-down" id="daily-dose">Daily-Dose</h1>
<h1 data-aos="fade-right" data-aos-anchor-placement="top-bottom" id="contents">Contents</h1>
<ul>
<li><a href="#from-new-yorker">From New Yorker</a></li>
<li><a href="#from-vox">From Vox</a></li>
<li><a href="#from-the-hindu-sports">From The Hindu: Sports</a></li>
<li><a href="#from-the-hindu-national-news">From The Hindu: National News</a></li>
<li><a href="#from-bbc-europe">From BBC: Europe</a></li>
<li><a href="#from-ars-technica">From Ars Technica</a></li>
<li><a href="#from-jokes-subreddit">From Jokes Subreddit</a></li>
</ul>
<h1 data-aos="fade-right" id="from-new-yorker">From New Yorker</h1>
<ul>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Saying Her Name</strong> - Remains that were found to be those of a Black teen who was killed by Philadelphia police in 1985 were treated as an anthropological specimen. How was her identity known and then forgotten? - <a href="https://www.newyorker.com/news/essay/saying-her-name">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Policing Politics Takes Over the New York City Mayoral Race</strong> - With the spectre of crime suddenly top of mind for many voters, the language of “defund the police” has been deemed a political liability. - <a href="https://www.newyorker.com/news/our-local-correspondents/policing-politics-takes-over-the-new-york-city-mayoral-race">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Japans Olympic-Sized Problem</strong> - The governments inept response to the coronavirus pandemic has led to widespread discontent about hosting the Games. - <a href="https://www.newyorker.com/culture/cultural-comment/japans-olympic-sized-problem">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Strange Story of Dagobert, the “DuckTales” Bandit</strong> - In the nineties, a frustrated artist in Berlin went on a crime spree—building bombs, extorting high-end stores, and styling his persona after Scrooge McDuck. He soon became a German folk hero. - <a href="https://www.newyorker.com/news/dispatch/the-strange-story-of-dagobert-the-ducktales-bandit">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Why Jerome Powell and the Fed Should Ignore the Inflation Hawks</strong> - Strong growth and a tight labor market are helping workers make sustained wage gains. - <a href="https://www.newyorker.com/news/our-columnists/why-jerome-powell-and-the-fed-should-ignore-the-inflation-hawks">link</a></p></li>
</ul>
<h1 data-aos="fade-right" id="from-vox">From Vox</h1>
<ul>
<li><strong>Seriously, just tax the rich</strong> -
<figure>
<img alt="A mobile billboard parked with the Capitol building in the background features a picture of Amazon CEO Jef Bezos and reads, “Tax me if you can!”" src="https://cdn.vox-cdn.com/thumbor/qSRyA07CLfyLXyb20O-VwTy5Png=/300x0:2967x2000/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/69304214/GettyImages_1232953214.0.jpg"/>
<figcaption>
A mobile billboard calling for higher taxes on the ultra-wealthy, to mark Tax Day, parked near the US Capitol on May 17. | Drew Angerer/Getty Images
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
What the debate about paying for infrastructure misses.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="dqtJxE">
Whether the government should tax rich people more to pay for spending priorities is a source of endless debate. Heres another idea: Tax the rich because its the right thing to do.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="vHHdfc">
Most recently, this debate has popped up around President Joe Bidens aspirations to invest in infrastructure, jobs, child care, and other items. The White House and many Democrats in Congress are wondering how (and whether) to pay for it. Some are <a href="https://www.axios.com/treasury-biden-tax-plan-infrastructure-c66280e2-c67f-43a8-8434-133bc06d30da.html">pushing to increase taxes</a> on the wealthy and corporations, arguing that they at least need to raise some revenue if they want to send so much money out the door.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="tiSPuG">
Others in the more progressive vein, however, question whether Democrats need to bother to come up with “pay-fors” at all. After all, Republicans didnt worry much about the deficit when they passed a $1.5 trillion tax cut back in 2017. Plus, they note, concerns about the debt can be widely overblown; interest rates are low and may be for a while, so if theres a moment to take on debt, its now. Its a politically useful stance because some moderate Democrats are <a href="https://www.washingtonpost.com/us-policy/2021/05/11/biden-taxes-democrats/?itid=ap_jeffstein">reportedly nervous</a> about the idea of raising taxes.
</p>
<div class="c-wide-block">
<figure class="e-image">
<img alt=" " src="https://cdn.vox-cdn.com/thumbor/qHP930WhKsQjf46mkSzakPrADvg=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/22521344/GettyImages_1256735037.jpg"/> <cite>Spencer Platt/Getty Images</cite>
<figcaption>
A “March on Billionaires” rally on July 17, 2020 in New York City. Organizers called on Gov. Andrew Cuomo to pass a tax on billionaires to fund workers excluded from unemployment and federal aid programs.
</figcaption>
</figure>
</div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="8EOUwd">
Sometimes, the haggling and hemming and hawing over what to do about the debt overshadow a point that <a href="https://www.msnbc.com/rachel-maddow-show/polls-show-broad-support-tax-hikes-wealthy-big-corporations-n1263833">many Americans find obvious</a>: Its simply a good, fair idea to tax the wealthy. They have disproportionately reaped the benefits of economic growth and the stock market in recent years, contributing to increasing inequality in the United States. The divide <a href="https://www.axios.com/treasury-biden-tax-plan-infrastructure-c66280e2-c67f-43a8-8434-133bc06d30da.html">has become even more obvious during the Covid-19 pandemic</a>, during which billionaires have managed to <a href="https://www.businessinsider.com/billionaires-added-4-trillion-to-their-wealth-during-the-pandemic-2021-4">add heaps of dollars</a> to their wealth even as millions of people were knocked on their heels. Some ultra-rich people in the US <a href="https://www.vox.com/recode/2019/11/1/20941440/tech-billionaires-rich-net-worth-philanthropy-giving-pledge">keep getting richer</a> no matter how much of their money they give away. They literally cannot stop adding to their coffers.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="TTU0pi">
“The market has produced an increasingly unequal distribution of income, and tax policy — and spending as well — are the way that we use government policy to push back and restrain those market-driven increases in inequality,” said David Wessel, a senior fellow in economic studies at the Brookings Institution and the director of the Hutchins Center on Fiscal and Monetary Policy. “The fact is that the market forces producing more inequality seem to be growing, and the governments willingness to use its power to push against that seems to be waning.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jxxPeY">
The chips of the economy are stacked in rich peoples favor, and theyre getting handed more chips constantly. So why not take a few chips away?
</p>
<h3 id="0S4oLv">
The wealthy are grabbing a big share of prosperity. The government can grab it back.
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ZCpM4E">
Rich people have done very well in the economy in recent decades. According to the <a href="https://www.cbo.gov/publication/55413">Congressional Budget Office</a>, the share of before-tax income captured by the richest 20 percent of households increased from 46 percent in 1979 to 54 percent in 2016. For the top 1 percent, income share went from 9 percent to 16 percent — <a href="https://www.taxpolicycenter.org/briefing-book/how-do-taxes-affect-income-inequality">more than the entire income</a> brought in by the bottom 40 percent of households. The 2017 tax cut bill <a href="https://www.bloomberg.com/graphics/2018-tax-plan-consequences/">disproportionately benefited</a> rich people and corporations. During the pandemic, <a href="https://www.pewresearch.org/social-trends/2021/03/05/a-year-into-the-pandemic-long-term-financial-impact-weighs-heavily-on-many-americans/">many high-income Americans say</a> that their financial situation has improved<em> </em>over the past year. They saved money they would have ordinarily spent on vacations and going out to eat, and as the stock market soared, so did their net worth.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="IBHxNf">
The wealthy are simply the group best able to afford to pay higher taxes. (Though to be sure, most people define the wealthy as “people who make more than me.”)
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="o2rCWL">
“We ought to start with the people who have benefited the most over the last couple of decades,” Wessel said.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="2lMBlT">
The US tax code is already somewhat progressive, though <a href="https://www.cfr.org/backgrounder/inequality-and-tax-rates-global-comparison">several other rich countries have significantly higher top income tax rates</a>, and <a href="https://taxfoundation.org/some-historical-tax-stats/#:~:text=The%20top%20marginal%20tax%20rate,taxed%20at%20the%20top%20rate.">the top income tax rate in the US used to be much higher, too</a>. According to a <a href="https://www.jct.gov/publications/2021/jcx-24-21/">recent report</a> from the Joint Committee on Taxation, people making more than $1 million in 2018 paid an average tax rate of 31.5 percent, and those making upward of $500,000 paid an average rate of 28.9 percent, combining income, payroll, excise, and corporate taxes. Still, there are plenty of ways that the wealthy use the tax code to their advantage — an advantage the White House is seeking to cut off.
</p>
<div class="c-float-right c-float-hang">
<aside id="EDhsd5">
<q>“When you have such a massive concentration of wealth in the hands of so few, that ultimately leads to a greater concentration of power in the hands of so few”</q>
</aside>
</div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="BbeWxA">
As it stands currently, long-term capital gains on investments such as stocks are <a href="https://www.investopedia.com/terms/c/capital_gains_tax.asp">taxed at a lower</a> rate than income. In other words, if you make money off of the sale of a stock youve had for a while, its taxed at a lower rate than if youd made the same amount of money through working. The Biden administration <a href="https://www.bloomberg.com/news/articles/2021-04-22/biden-to-propose-capital-gains-tax-as-high-as-43-4-for-wealthy">is eyeing overhauling</a> the capital gains rate for people making $1 million or more, so that those gains would be taxed at the highest individual rate, which the presidents tax plan would put at 39.6 percent. (The 2017 tax bill lowered the highest rate to 37 percent). The White House is also pushing Congress to close the <a href="https://www.nytimes.com/2021/04/23/business/dealbook/carried-interest-biden.html">carried interest loophole</a> that lets private equity and hedge fund managers have their gains taxed at a lower rate.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jny1wN">
Democrats are also looking at changing how inherited wealth is taxed, including the “<a href="https://www.nytimes.com/2021/01/15/your-money/estate-tax-biden.html">stepped-up basis</a>” tax code provision. As it stands, if a rich person sees their wealth go up by $1 billion in, for example, stock, when they sell that investment, theyll be taxed on their $1 billion gain. But if they never sell and the investment gets passed to their heirs when they die, their heirs are taxed at the baseline of what its worth when they get it. If and when they sell, theyre only taxed on new gains.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ImkDKm">
“We dont collect as much as we ought to from rich guys because they could hold their stock until death, and then their heirs get a stepped-up basis, and all the gains, all the appreciation over their lifetimes, is simply income taxes avoided,” said Steve Rosenthal, a senior fellow at the Urban Institutes Tax Policy Center.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="EyVQ56">
Biden has also proposed trying to raise taxes on the wealthy without really touching the tax code and just trying to more fully collect what they already owe. He <a href="https://www.vox.com/22405898/joe-biden-irs-funding">wants Congress to direct</a> some $80 billion to the IRS over the next decade to try to beef up enforcement and close the “tax gap” — the difference between what the IRS gets in taxes versus what it is owed. IRS chief Charles Rettig <a href="https://www.reuters.com/article/us-usa-treasury-irs/irs-chief-says-1-trillion-in-taxes-goes-uncollected-every-year-idUSKBN2C0255">has estimated</a> that it could amount to $1 trillion every year.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="w3om5O">
A <a href="https://www.nber.org/system/files/working_papers/w26475/w26475.pdf">2019 paper</a> from Natasha Sarin, now deputy assistant secretary at the Treasury Department, and economist Larry Summers estimated that the tax gap would total $7.5 trillion from 2020 to 2029, with most benefits going to the wealthy. (<a href="https://www.irs.gov/newsroom/irs-releases-new-tax-gap-estimates-compliance-rates-remain-substantially-unchanged-from-prior-study#:~:text=The%20average%20gross%20tax%20gap,was%20estimated%20at%20%24381%20billion.">Official IRS estimates</a> from 2011 to 2013 put the tax gap at about $441 billion each year.)
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="oaPOmv">
In March this year, the Washington Center for Equitable Growth published a <a href="https://equitablegrowth.org/working-papers/tax-evasion-at-the-top-of-the-income-distribution-theory-and-evidence/">paper</a> on tax evasion that estimated the top 1 percent of earners underreport about one-fifth of their income. The research suggested that collecting all unpaid federal income tax from the richest Americans would increase revenues by $175 billion each year. However, tax enforcement is difficult and takes a long time. (<a href="https://www.vox.com/policy-and-politics/21492209/donald-trump-income-taxes-ny-times-evasion-avoidance">Remember Donald Trumps taxes and endless audits</a>?) IRS agents with the adequate experience and know-how to deal with complex audits <a href="https://www.taxpolicycenter.org/taxvox/america-we-have-problem-irs-brain-drain">can take years</a> to train and replace. And even once the IRS is staffed up, its unlikely it will be able to capture all the money thats owed.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4prTh0">
Rosenthal has <a href="https://www.taxpolicycenter.org/taxvox/if-congress-wants-irs-collect-more-tax-rich-it-needs-pass-better-laws">expressed concerns</a> about the estimates from the Washington Center for Equitable Growth paper and says he believes the answer is to beef up the tax code with simpler laws that require additional reporting. It is true that the IRS could collect more in taxes, but rich people are pretty good at avoiding that. He prefers to raise taxes on corporations — Biden has proposed increasing the corporate tax rate from 21 percent to 28 percent — as a way to tax the rich. <a href="https://www.taxpolicycenter.org/taxvox/who-owns-us-stock-foreigners-and-rich-americans">Wealthy people and foreigners disproportionately own stocks</a> and benefit from slashes to the corporate tax rate.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="nSR0IU">
“When we increase taxes on corporations, which falls on shareholders, it falls on those who have already benefited from Trumps tax cuts and who have overwhelmingly benefited from the run-up in the stock market,” Rosenthal said.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="6c2Zvj">
Beyond whats on the White Houses agenda, there is a plethora of proposals for taxing the wealthy. Sen. Elizabeth Warren (D-MA) ran on <a href="https://www.vox.com/policy-and-politics/2019/1/24/18196275/elizabeth-warren-wealth-tax">a wealth tax</a>, which would tax the fortunes of the super-rich, though <a href="https://www.politico.com/news/2021/03/30/biden-elizabeth-warren-wealth-tax-478642">Biden has not embraced it</a>. Senate Budget Committee Chair Bernie Sanders (I-VT) <a href="https://www.cnbc.com/2021/03/25/bernie-sanders-introduces-bills-to-hike-corporate-taxes-estate-tax.html">recently rolled out his own proposal</a> to tax corporations and the rich as well.
</p>
<aside id="cCRaTa">
<div>
</div>
</aside>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="qKjcwO">
One challenge to making any changes to the tax law is making sure they are robust enough that people dont just find a way to avoid them. “If you spend a lot of political capital on taxing the rich and you spend a lot of time setting up something … and then you discover the people you want to tax are extremely good at finding ways not to pay the tax, then have you really accomplished anything?” Wessel said.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="uFmFca">
Some Republicans and business leaders fear that if the US taxes rich people and companies too much, it will make the country less competitive, or the wealthy will flee. Democrats <a href="https://www.vox.com/policy-and-politics/2021/4/14/22375306/salt-tax-deduction-repeal">pushing to get rid of the cap on the state and local tax deduction</a> — which generally impacts well-off people in blue states — argue that the cap will encourage wealthy people to go to lower-tax states. But theres <a href="https://inequality.stanford.edu/sites/default/files/media/_media/pdf/pathways/summer_2014/Pathways_Summer_2014_YoungVarner.pdf">not a lot of evidence of millionaire migration</a> from blue states to red states over the tax code. And many rich people and corporations prefer to live and do business in the US, even if it means a slightly higher tax liability.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="EfUJIZ">
“The Republicans think every time you tax someone whos rich … somehow, theyll work less hard, invest less, and well all suffer. And Democrats say thats simply not true,” Wessel said. “I think the evidence is on the Democrats side, as long as you dont overdo it.”
</p>
<h3 id="dSHS9e">
Taxing the rich makes the economy feel fairer
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="EKWJ0d">
Lots of people right now say the economy seems unfair. It feels like the system is rigged in favor of the people who need help the least. And that makes many people lose faith in the economy — its easier to believe in America when you feel like America isnt stacked for winners.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Gnx1fx">
Thats part of why taxing rich people and corporations is so popular. Like, really, really popular. Eight in 10 Americans <a href="https://www.pewresearch.org/fact-tank/2021/04/30/top-tax-frustrations-for-americans-the-feeling-that-some-corporations-wealthy-people-dont-pay-fair-share/">say they are bothered</a> by some corporations and the wealthy not paying their fair share in taxes, according to Pew Research Center. A <a href="https://morningconsult.com/2021/03/31/biden-infrastructure-plan-raising-taxes-wealthy-corporations/">recent Morning Consult/Politico poll</a> found that paying for infrastructure by increasing taxes on those groups made Bidens infrastructure plan more popular, not less.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="dZhklo">
Taxing rich people cant pay for everything Democrats would perhaps like to, but for many progressives, thats beside the point.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="v1U4ae">
“We do not have to tax to have nice things, we tax for predistribution and redistribution. In order to have nice things, we print money and we invest in the things that we need,” said Solana Rice, co-founder and co-executive director of Liberation in a Generation, which pushes for economic policies that reduce racial disparities. “We almost couldnt tax enough to really pay for all the things that we need, so its a ruse.”
</p>
<div class="c-wide-block">
<figure class="e-image">
<img alt=" " src="https://cdn.vox-cdn.com/thumbor/N5DZKGUPmQyMEUdOlP1tn1mXPcE=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/22521358/GettyImages_1256734950.jpg"/> <cite>Spencer Platt/Getty Images</cite>
<figcaption>
One challenge to making any changes to the tax law is making sure they are robust enough that people dont just find a way to avoid them.
</figcaption>
</figure>
</div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ztgOFQ">
With money comes power, and taxing those who can afford it more fairly could result in a more even distribution of that. “When you have such a massive concentration of wealth in the hands of so few, that ultimately leads to a greater concentration of power in the hands of so few,” said Dana Bye, campaign director of the Tax March, a progressive tax group. Overhauling the tax code wont fix all of the countrys issues, but it might not hurt, either, and could address some egregious imbalances. Billionaire investor Warren Buffett <a href="https://money.cnn.com/2013/03/04/news/economy/buffett-secretary-taxes/index.html">claimed to pay a lower tax rate than his secretary</a> for years; former President Donald Trump <a href="https://www.vox.com/policy-and-politics/21492209/donald-trump-income-taxes-ny-times-evasion-avoidance">bragged about his low tax liability</a>.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="OKAILJ">
What happens to revenue from potential tax increases matters — if Democrats want to tax the wealthy in order to help people at the bottom of the income spectrum or pay for infrastructure, it is important that theyre deliberate about that. And raising taxes is never easy: There are plenty of constituents, from business groups to lobbyists to voters, who push back.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="76BSyb">
“Thats why Congress has been doing all of these deficit spending bills,” Rosenthal said. “Its hard to get anyone to agree on taxes.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="y5TmB7">
But just because it is hard to tax rich people doesnt mean Democrats shouldnt do it. Biden has promised to go big and bold on the economy and push the country in a more progressive, broadly beneficial direction. This is a way to help him get there.
</p></li>
<li><strong>Brett Kavanaughs latest decision should alarm liberals</strong> -
<figure>
<img alt="" src="https://cdn.vox-cdn.com/thumbor/pY-M04zwp-CRuTHoL_7n8PlMS3Q=/259x0:4506x3185/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/69304096/1068141116.jpg.0.jpg"/>
<figcaption>
Justice Brett Kavanaugh at a ceremony for the late President George H.W. Bush at the Capitol in 2018.  | Jabin Botsford/Getty Images
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
The Courts new median justice really doesnt care about precedent.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="gCF4jf">
The Supreme Court took two actions on Monday that hint that many Democrats worst fears about the Courts 6-3 Republican majority might come true.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="eIHZZN">
The first was the Courts announcement that it will hear <a href="https://www.scotusblog.com/case-files/cases/dobbs-v-jackson-womens-health-organization/"><em>Dobbs v. Jackson Womens Health Organization</em></a>, a challenge to a Mississippi law banning nearly all abortions after 15 weeks of pregnancy. <em>Dobbs</em> is potentially an <a href="https://www.vox.com/2021/5/17/22233440/supreme-court-abortion-roe-wade-dobbs-jackson-womens-health-amy-coney-barrett">existential threat to the constitutional right to an abortion</a>, and it tees up the question of whether this Court is willing to overrule venerable decisions like <em>Roe v. Wade</em>, which are beloved by liberals and loathed by conservatives.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="BrjOJN">
The second action involved a more obscure case. Last year, in <a href="https://scholar.google.com/scholar_case?case=7527212875137340599&amp;hl=en&amp;as_sdt=6&amp;as_vis=1&amp;oi=scholarr"><em>Ramos v. Louisiana</em></a>, the Supreme Court held that no one could be convicted of a “serious crime” unless a jury voted unanimously to convict them. On Monday, the Supreme Court held in <a href="https://www.supremecourt.gov/opinions/20pdf/19-5807_086c.pdf"><em>Edwards v. Vannoy</em></a> that <em>Ramos</em> is not retroactive — meaning that nearly all people convicted by non-unanimous jury verdicts before <em>Ramos</em> was decided will not benefit from the <em>Ramos</em> decision.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="YzDHsK">
On the surface, the Courts decision to hear a major abortion case, and its decision not to apply one of its criminal justice precedents retroactively, may appear to have little in common. But taken together, they foreshadow a world where the Courts new majority is willing to overturn longstanding precedents, potentially with little justification for doing so other than that the Courts Republican majority would prefer to overrule liberal decisions such as <em>Roe</em>.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XrAMdJ">
Because heres the thing: <em>Edwards</em> did not simply limit the scope of <em>Ramos</em>. Justice Brett Kavanaughs majority opinion also overruled a 32-year-old decision governing when the Supreme Courts precedents apply retroactively. Kavanaugh did so, moreover, without following the ordinary procedures that the Court normally follows before overruling one of its previous decisions. As Justice Elena Kagan points out in dissent, no one asked the Court to overrule anything in <em>Edwards</em>, and the Court “usually confines itself to the issues raised and briefed by the parties.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="I9CgEe">
<em>Edwards</em>, moreover, is the second time in less than a month that Kavanaugh authored a majority opinion that overrules a prior decision without following the Courts normal procedures. In late April, Kavanaugh handed down a decision in <a href="https://www.supremecourt.gov/opinions/20pdf/18-1259_8njq.pdf"><em>Jones v. Mississippi</em></a> that effectively overruled a <a href="https://scholar.google.com/scholar_case?case=9236378392139374560&amp;hl=en&amp;as_sdt=6&amp;as_vis=1&amp;oi=scholarr">2016 decision</a> establishing that nearly all juvenile offenders may not be sentenced to life without parole.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="eAShsH">
But <em>Jones</em> overruled this 2016 decision in such an oblique and underhanded way that several of Kavanaughs colleagues came very close to accusing him of lying about what he was doing. Even Justice Clarence Thomas, the Courts most conservative member, chided Kavanaugh for overruling a previous decision “in substance but not in name.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="WU1ADe">
The Court historically has been <a href="https://www.vox.com/2020/3/25/21192320/supreme-court-comcast-decision-civil-rights-mixed-motive-lawsuits">very reluctant to overrule precedents</a>, both because past justices understood that the law should be predictable, and because strong norms against overruling past decisions help prevent the Supreme Court from becoming a purely partisan prize — tossing out decades worth of settled doctrines every time a different political party gains control of the Court.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="krjRRj">
But Kavanaugh does not appear to share his predecessors reluctance to overrule past decisions.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="oBBZ1Y">
All of this matters because Kavanaugh is the median vote on the Supreme Court. Last week, SCOTUSBlog published an analysis finding that Kavanaugh voted with the majority in <a href="https://www.scotusblog.com/2021/05/on-a-new-conservative-court-kavanaugh-sits-at-the-center/">97 percent of cases</a> decided so far this Supreme Court term — more than any other justice. If you want to win a case before the Supreme Court, youve got a tough road ahead of you if you cant secure Kavanaughs vote.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="I4G7yK">
And yet, Kavanaugh is signaling in <em>Edwards</em>, <em>Jones</em>, and in a few other significant opinions that he does not particularly care about precedent, and that he is willing to overrule prior decisions for reasons that previous Supreme Courts would have deemed trivial and unwarranted.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="CAdycu">
With conservatives holding a 6-3 supermajority on the Supreme Court, thats terrible news for liberals. And it doesnt just mean that precedents like the Courts pro-abortion decision in <a href="https://www.law.cornell.edu/supremecourt/text/410/113"><em>Roe v. Wade</em></a> (1973) are in danger.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="nsXBCl">
Kavanaugh, the closest thing that this Supreme Court has to a “swing” justice, is telling us that hes very willing to overrule a wide range of precedents. And a majority of the Court appears to agree with his approach. Thats potentially disastrous news for anyone hoping that this Supreme Court would honor past decisions that protect liberal democratic values.
</p>
<h3 id="PLQ79J">
So what happened in <em>Edwards</em>, exactly?
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Kg0MWL">
<em>Edwards</em> involved a question that comes up fairly often in the Courts criminal justice decisions: When the Court announces a new constitutional rule governing criminal convictions or sentences, does that rule apply retroactively to people whose convictions or sentences were already final when the new rule was handed down?
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="MAKrBk">
In <a href="https://scholar.google.com/scholar_case?case=9178485170219770923&amp;hl=en&amp;as_sdt=6&amp;as_vis=1&amp;oi=scholarr"><em>Teague v. Lane</em></a> (1989), the Supreme Court identified a few limited circumstances when a new rule should apply retroactively. The first circumstance is if the new rule places “certain kinds of primary, private individual conduct beyond the power of the criminal law-making authority to proscribe.” Thus, for example, if the Supreme Court were to hold that it is unconstitutional to convict someone for marijuana possession, then that rule would apply retroactively because it places the act of possessing marijuana “beyond the power of the criminal law-making authority to proscribe.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="YdDOr5">
Subsequent Supreme Court decisions clarified that a new criminal justice rule also applies retroactively if it forbids “a certain category of punishment for a class of defendants <a href="https://scholar.google.com/scholar_case?case=9236378392139374560&amp;hl=en&amp;as_sdt=6&amp;as_vis=1&amp;oi=scholarr">because of their status or offense</a>.” Thus, for example, when the Supreme Court held in <a href="https://scholar.google.com/scholar_case?case=2043469055777796288&amp;hl=en&amp;as_sdt=6&amp;as_vis=1&amp;oi=scholarr"><em>Atkins v. Virginia</em></a><em> </em>(2002) that intellectually disabled people are not eligible for the death penalty, that rule was retroactive because it determined that a certain class of people could not receive a certain category of punishment.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="gZPStA">
<em>Teague</em> held that “<a href="https://scholar.google.com/scholar_case?case=9178485170219770923&amp;hl=en&amp;as_sdt=6&amp;as_vis=1&amp;oi=scholarr">watershed rules of criminal procedure</a>” are also retroactive. The <em>Edwards</em> case asked whether the rule announced in <em>Ramos — </em>the rule that no one can be convicted of a serious crime unless the jury verdict is unanimous — was such a watershed rule.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="RPyOAO">
In holding that <em>Ramos</em> did not announce such a “watershed” rule, Kavanaugh explains that the bar for determining what constitutes a watershed rule is quite high. Indeed, in the Courts entire history, its only identified one such rule: the decision in <a href="https://www.law.cornell.edu/supremecourt/text/372/335"><em>Gideon v. Wainwright</em></a> (1963) holding that indigent criminal defendants are entitled to defense counsel paid for by the state.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jo5DAQ">
And yet, rather than just holding that <em>Ramos</em> did not announce a watershed rule and leave it at that, Kavanaughs opinion goes much further. “Some 32 years after <em>Teague</em>,” Kavanaugh writes, its now clear that “no new rules of criminal procedure can satisfy the watershed exception.” Thus, he concludes, “we cannot responsibly continue to suggest otherwise to litigants and courts.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="SqBV1N">
<em>Edwards</em> holds that no new watershed rules exist, no matter what the circumstances. <em>Teague</em>s verdict on watershed rules is now overruled.
</p>
<h3 id="cSPS9M">
Kavanaughs shifting justifications for overruling prior decisions
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="AjgmH5">
The Courts decision to overrule part of <em>Teague</em> is surprising for several reasons. For one thing, as Kagan notes in her dissent, no one asked the Court to do so. Typically, before the Court overrules a precedent, it seeks out briefing from the parties on whether that precedent should be overruled — that way, if there will be some disastrous or unexpected consequence if the precedent is overruled, the parties can warn the justices about it in advance.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="MLciTH">
Kavanaugh also does not appear to have followed his own rules governing when a previous Court decision should be overruled. In <em>Ramos</em>, the Court effectively overruled another decision, <a href="https://scholar.google.com/scholar_case?case=17083848214568933382&amp;hl=en&amp;as_sdt=6,47&amp;as_vis=1"><em>Apodaca v. Oregon</em></a> (1972), which permitted states to convict criminal defendants via a non-unanimous jury vote. Kavanaugh agreed with this result in <em>Ramos</em>, but he also wrote a separate opinion laying out when he thinks it is acceptable for the Supreme Court to overrule a prior decision.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="IjLqfU">
When deciding whether to overrule a precedent, Kavanaugh wrote, the Court should consider whether the previous decision is “not just wrong, but grievously or egregiously wrong.” It should consider whether “the prior decision caused significant negative jurisprudential or real-world consequences,” and it should ask whether overruling the prior precedent would upset “legitimate expectations of those who have reasonably relied on the precedent.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="STcZWQ">
But Kavanaugh engaged in none of this analysis in <em>Edwards</em>, and its hard to see how <em>Teague</em> would qualify as worthy of being overruled under the standard Kavanaugh articulated in <em>Ramos</em>. Kavanaugh doesnt claim in <em>Edwards</em> that <em>Teague</em> was egregiously wrong or that its led to “significant negative jurisprudential or real-world consequences.” Indeed, he claims the exact opposite — that <em>Teague</em>s holding regarding “watershed” rules should be overruled because its had no jurisprudential or real-world consequences whatsoever.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ks0Qqe">
Kavanaugh also ignored the standard he laid out in <em>Ramos</em> in his opinion in <em>Jones v. Mississippi, </em>the decision involving whether juveniles who commit homicide crimes can be sentenced to life without parole.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="s7BOeH">
In <a href="https://scholar.google.com/scholar_case?case=6291421178853922648&amp;hl=en&amp;as_sdt=6&amp;as_vis=1&amp;oi=scholarr"><em>Miller v. Alabama</em></a> (2012), the Supreme Court held that most people who commit a crime before their 18th birthday may not be sentenced to life without parole, even if the crime is murder. And, in <a href="https://scholar.google.com/scholar_case?case=9236378392139374560&amp;hl=en&amp;as_sdt=6&amp;as_vis=1&amp;oi=scholarr"><em>Montgomery v. Louisiana</em></a> (2016), the Court held that <em>Miller</em> applies retroactively because it prohibited a certain category of offenders (nearly all juvenile offenders) from receiving a certain punishment (life without parole).
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Cuwd4Y">
<em>Miller </em>and <em>Montgomery</em> did, however, suggest that a very small category of juvenile offenders, “those whose crimes reflect permanent incorrigibility,” are still eligible for life without parole. The issue in <em>Jones</em> was whether a sentencing judge must explicitly determine that a particular juvenile offender is “permanently incorrigible” before sentencing them to life without parole.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="YdSwOn">
Kavanaughs decision in <em>Jones</em> doesnt simply hold that sentencing judges do not need to make this determination; it eliminates <em>Montgomery</em>s holding that nearly all juvenile offenders are categorically ineligible for life without parole. Kavanaughs opinion in <em>Jones</em> establishes that all juvenile homicide offenders may be sentenced to life without parole, so long as they are sentenced in a “discretionary” proceeding where the judge has the option to impose a lighter sentence.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="EO1GlV">
“In a case involving an individual who was under 18 when he or she committed a homicide,” Kavanaugh wrote for the new, more conservative majority that decided the <em>Jones</em> case, “a States discretionary sentencing system is <a href="https://www.supremecourt.gov/opinions/20pdf/18-1259_8njq.pdf">both constitutionally necessary and constitutionally sufficient</a>.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="fhGRFc">
Four justices called Kavanaugh out for overruling <em>Montgomery</em> without being entirely honest about what he was up to. Though Thomas agreed with Kavanaugh that <em>Montgomery</em> should be overruled, he wrote that the Court should be more candid when it overrules a prior precedent. Hence his dig at Kavanaugh for overruling <em>Montgomery</em><a href="https://www.supremecourt.gov/opinions/20pdf/18-1259_8njq.pdf">in substance but not in name</a>.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="7NoEjP">
Meanwhile, the Courts three liberal justices joined an opinion by Justice Sonia Sotomayor that walked right up to the line of accusing Kavanaugh of lying about what he was up to in his majority opinion. “The Court simply rewrites <em>Miller</em> and <em>Montgomery</em> to say what the Court now wishes they had said, and then denies that it has done any such thing,” Sotomayor wrote. “The Court,” she added, “<a href="https://www.supremecourt.gov/opinions/20pdf/18-1259_8njq.pdf">knows what it is doing</a>.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="5twyME">
Kavanaughs loose approach to precedent, in other words, isnt simply being noticed by legal experts and court-watchers. Its being noticed by Kavanaughs colleagues to his right and to his left — and four of them recently called him out for it.
</p>
<h3 id="JglmX0">
Kavanaughs views on precedents endanger American democracy
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="FgB514">
Theres at least one other important case where Kavanaugh revealed that he is eager to toss out several longstanding precedents — and that case has tremendous implications for whether the United States will have anything resembling free and fair elections in the future.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="nExM6q">
In election years, state election officials and state court judges often hand down decisions implicating how the election will be run — and who will be allowed to vote in that election. This was <a href="https://www.vox.com/2020/10/28/21539169/supreme-court-pennsylvania-republican-party-samuel-alito-mail-in-ballots-boockvar">especially true in 2020</a>, as many state election boards and state courts tried to accommodate voters who were afraid to visit a polling place during a pandemic.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="BAMGtn">
Many Republicans did not like many of these decisions by election officials and state courts, which made it easier for many voters to cast a ballot, so they brought a series of lawsuits arguing that these efforts to expand access to voting were unconstitutional. The crux of these Republicans arguments was that the Constitution <a href="https://www.vox.com/2020/10/28/21539169/supreme-court-pennsylvania-republican-party-samuel-alito-mail-in-ballots-boockvar">only permits state <em>legislatures</em></a>, and not state courts or other state election officials, to determine how a state conducts a federal election.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="0KmAhU">
This is not a new argument, but its one that the Supreme Court has <a href="https://www.vox.com/2020/11/3/21546419/supreme-court-2020-election-question-pennslyvania-minnesota-texas-north-carolina">repeatedly rejected</a> in a long line of decisions that stretch back more than a century. The Court most recently rejected this argument in <a href="https://www.law.cornell.edu/supremecourt/text/13-1314#writing-13-1314_OPINION_3"><em>Arizona State Legislature v. Arizona Independent Redistricting Commission</em></a> (2015), which reaffirmed that a states power to enact election laws is “to be performed in accordance with the States prescriptions for lawmaking.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="hAUkW2">
So, if a states constitution protects the right to vote, these protections may be enforced by the states courts. And if the state constitution allows statewide boards to be given the power to interpret state laws, then a state election board may be given the power to interpret state election law.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4O1ZbR">
Nevertheless, in <a href="https://utexas.app.box.com/s/pd70m6vmah3xf3h7je69pgmnunwuscbm"><em>Democratic National Committee v. Wisconsin State Legislature</em></a> (2020), Kavanaugh joined an opinion by Justice Neil Gorsuch that would have overruled <em>Arizona State Legislature</em> as well as a line of Supreme Court decisions <a href="https://www.law.cornell.edu/supremecourt/text/241/565">stretching back at least as far as 1916</a> — though its worth noting that Gorsuchs opinion was not joined by a majority of his colleagues.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="GbGjsu">
“The Constitution provides that state legislatures — not federal judges, not state judges, not state governors, not other state officials — bear primary responsibility for setting election rules,” Gorsuch claimed in his opinion.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="39jzmH">
Taken to its logical extreme, Gorsuch and Kavanaughs approach would have profound implications for future elections. It could mean that Democratic state governors in states with Republican legislatures — such as Wisconsin, Michigan, and Pennsylvania — are not allowed to veto most state election laws, including congressional gerrymanders.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XwvKA3">
It could also mean that state courts are not allowed to enforce state constitutional provisions protecting the right to vote or forbidding gerrymandering. And it could invalidate independent redistricting commissions that take the power to draw congressional districts out of the hands of a partisan state legislature.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="qsoUn7">
To date, four justices — Gorsuch and Kavanaugh, plus Justices Thomas and Samuel Alito — have <a href="https://www.vox.com/2020/10/28/21539169/supreme-court-pennsylvania-republican-party-samuel-alito-mail-in-ballots-boockvar">endorsed the approach</a> Gorsuch and Kavanaugh took in <em>Democratic National Committee</em>. Justice Amy Coney Barrett was not on the Court when <em>Democratic National Committee</em> was handed down, and has thus far not weighed in on the question of whether state legislatures have unchecked power over how states conduct federal elections — so the decision whether to implement this rule likely rests in her hands.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="So0VBo">
In any event, Kavanaugh, the median justice on most contentious issues that arise before the Court, is perfectly willing to overrule more than a century worth of precedent. And hes willing to do so even when overruling those precedents would upend fundamental assumptions about how state election laws work — and who is in charge of deciding how our elections are conducted.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="B3mFel">
More broadly, much of American law — the <a href="https://www.law.cornell.edu/supremecourt/text/11-393">constitutionality of the Affordable Care Act</a>, the <a href="https://www.vox.com/2020/6/29/21306895/supreme-court-abortion-chief-justice-john-roberts-stephen-breyer-june-medical-russo">right to an abortion</a>, the <a href="https://www.vox.com/2019/11/26/20981758/brett-kavanaughs-terrify-democrats-supreme-court-gundy-paul">power of the EPA to protect the environment</a>, the power of states to <a href="https://www.supremecourt.gov/opinions/17pdf/16-111_j4el.pdf">require businesses not to discriminate</a> against LGBTQ workers and customers, and numerous other laws — hinges on the Supreme Courts willingness to honor past decisions that Republicans dont like very much.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XKfEpH">
Liberals, in other words, are depending on the doctrine of <a href="https://www.vox.com/2020/6/29/21306895/supreme-court-abortion-chief-justice-john-roberts-stephen-breyer-june-medical-russo">stare decisis</a> — the idea that courts should typically be bound by their prior decisions — to stave off a conservative legal revolution.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="7OKN6z">
And as liberals shout for stare decisis to save them, the Courts median justice is looking down upon them, and <a href="https://www.superverbose.com/2015/11/21/the-annotated-annotated-watchmen-18-a-real-rain/">whispering “no.”</a>
</p></li>
<li><strong>The battle for the future of “gig” work</strong> -
<figure>
<img alt="An illustration of a ride-share driver behind the wheel of a car." src="https://cdn.vox-cdn.com/thumbor/wktcXsBiuEwHCtyksWZ2rYP8364=/72x0:1512x1080/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/69265597/Vox_Final.0.jpg"/>
<figcaption>
Kailey Whitman for Vox
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Ride-sharing companies are pushing to make a third category of “independent” worker the law of the land. Drivers say the notion of independence is little more than a mirage.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Lkb7qc">
</p>
<div class="c-float-left">
<figure class="e-image">
<img alt=" " src="https://cdn.vox-cdn.com/thumbor/YYgW4HsU995yniG4Y5QuEoQvF0Y=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/21899595/VOX_The_Highlight_Box_Logo_Horizontal.png"/>
</figure>
</div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="U5gRuI">
Part of <a href="https://www.vox.com/the-highlight/22424892/the-fairness-issue">The Fairness Issue</a> of <a href="https://www.vox.com/the-highlight"><strong>The Highlight</strong></a>, our home for ambitious stories that explain our world.
</p>
<hr class="p-entry-hr" id="kwgfCa"/>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="hfzE3F">
Erica Mighetto has been a driver for ride-hail platforms for four years, and has stories, she says, that span the spectrum “from being solicited for sex to meeting some great people that are still my friends to this day.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="LMBGR5">
When she got started, she expected it to be a transitional thing, a gig between more permanent jobs. Shed worked in accounting for 15 years and was employed by a property management company where, she says, “a lot of my role became evicting people from their homes, and I just wasnt happy there.” But she actually liked being a driver more than shed thought, and at first, with Lyft, she was making decent money — an average of $40 an hour.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="JZCmGb">
“I really enjoyed getting away from the cubicle and into the world and sharing peoples experiences,” she says. “I always said that I really loved having the word on the street. You find out not just the best places to eat but the best person to do your taxes, everything thats going on in your community. You have a real finger on the pulse.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="KM6Pxa">
Mighetto, 39, is from Sacramento, California, and she used to drive to the Bay Area every now and then to work for a long weekend and make more money; she could bring in as much as $80 an hour on a holiday or during a big event. The company offered bonuses for many things: a hot streak — say, $15 for three rides in a row in a prescribed time frame, or sign-on bonuses if they referred another driver, or weekly bonuses for a certain number of rides. But as time went on, she says, echoing many drivers from both Lyft and Uber, she found that her bonuses were lower, and suddenly, she was making the hour-and-a-half drive every weekend just to get by. “They kept moving the goalposts,” she says.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="N4NeaU">
The experience was much the same for Seydou Ouattara, a driver for Uber in New York. When he began driving in 2016, he was doing pretty well, but over the years, he says, “I was working more hours for Uber, but I was making less money.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="C6a50S">
Mighettos and Ouattaras experiences — of both promised freedom and frustration — are increasingly common in the United States as the “gig economy” grows. Companies like Uber and <a href="https://go.redirectingat.com?id=66960X1516588&amp;xs=1&amp;url=https%3A%2F%2Fwww.lyft.com%2Fimpact%2Feconomic-impact-report%2F%2Fstats%2Fstates%2Fcalifornia&amp;referrer=vox.com&amp;sref=https%3A%2F%2Fwww.vox.com%2Fthe-highlight%2F22425152%2Ffuture-of-gig-work-uber-lyft-driving-prop-22" rel="sponsored nofollow noopener" target="_blank">Lyft</a> have argued that gig workers need to be excluded from employee status to preserve their flexibility, and that most of their drivers are <a href="https://www.businessinsider.com/uber-lyft-ab5-fight-reveals-dependence-full-time-drivers-2020-8">part-time</a> hustlers, not full-time professional drivers.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="aVC03a">
Since Uber launched in 2011 as “<a href="https://www.businessinsider.com/uber-old-app-new-york-city-ipo-2019-5#heres-what-it-looked-like-when-requesting-a-pickup-in-ubers-app-back-when-it-launched-in-new-york-in-2011-the-interface-is-much-simpler-and-the-design-language-is-completely-different-1">UberCab</a>” with the aim of “disrupting” the taxi industry, the gig economy has exploded into a variety of fields and classified swaths of workers as independent contractors rather than employees. That allows companies to avoid minimum wage and overtime laws as well as unemployment insurance, workers compensation, and payroll taxes.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jcB3Cj">
This is billed as innovation, but its actually a tactic that goes back more than a century. US labor law history is rife with different groups of workers being carved out of protections because their work wasnt really seen as work.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="J5ET9g">
Modern-day gig workers such as Mighetto and Ouattara have been pushing back, arguing that the amount of control the apps exercise over them (not to mention the big money they make for the gig companies) means that the work they do should come with the benefits of being an employee.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="TTXp9U">
Last November, California passed a ballot initiative called Proposition 22, cementing Mighetto and her colleagues in <a href="https://prospect.org/labor/prop-22-is-here-already-worse-than-expected-california-gig-workers/">semi-employee status</a>. They still dont get state unemployment, discrimination protections, sick leave, or collective bargaining rights, though they do have some bare-minimum guarantees of pay while actually carrying a passenger. The minimums were sold as a baseline that increased driver rights, but one <a href="https://laborcenter.berkeley.edu/the-uber-lyft-ballot-initiative-guarantees-only-5-64-an-hour-2/">study by University of California Berkeley</a> researchers found that the guarantee could actually only be “the equivalent of a wage of $5.64 per hour.”
</p>
<figure class="e-image">
<img alt=" " src="https://cdn.vox-cdn.com/thumbor/7qYi_e5XwucJE8d-K7XLbQpbiA8=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/22499270/GettyImages_1133000006.jpg"/> <cite>Timothy A. Clary/AFP/Getty Images</cite>
<figcaption>
An iPhone with the Lyft ride-hailing app on it shows cars in the area.
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XMcb46">
“Im a driver,” Mighetto says, “and that doesnt give anyone license to treat me like a third-class citizen.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="9sy7it">
In response to requests from Vox for comment, representatives for Uber and Lyft defended their model and practices, offering surveys and articles they contend show that drivers prefer their independent contractor status. “Driver earnings are currently at an all-time high in many of our markets,” a spokesperson for Lyft wrote in an email.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Aj8oQP">
Workers across the country are now worried that the effects of Prop 22 will spread, institutionalizing a “third category” of workers well beyond Uber and Lyft drivers who have fewer rights than regular employees but also lack the real autonomy of actual freelancers — and that it might happen under a Democratic administration, and with the sign-off of some labor unions.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="epI7ZY">
In other words, were at an inflection point, potentially for the entire American working class. Will labor figure out how to organize workers in dire conditions across the broad spectrum of “tech”-enabled jobs, from Amazon to Uber? Or are workers going to continue to see their conditions deteriorate, even as executives at the top <a href="https://www.marketwatch.com/story/uber-ceo-other-execs-saw-pay-cuts-in-2020-but-still-raked-in-millions-11615593162">just get richer</a>?
</p>
<hr class="p-entry-hr" id="FT1PM1"/>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="rObgPM">
In 2019, the clutch went out on Mighettos car, so she was driving for Lyft in a rental car to make the $1,500 she needed for the repair. (Lyft, she explains, has a <a href="https://go.redirectingat.com?id=66960X1516588&amp;xs=1&amp;url=https%3A%2F%2Fwww.lyft.com%2Fexpressdrive&amp;referrer=vox.com&amp;sref=https%3A%2F%2Fwww.vox.com%2Fthe-highlight%2F22425152%2Ffuture-of-gig-work-uber-lyft-driving-prop-22" rel="sponsored nofollow noopener" target="_blank">rental partnership</a> so drivers can get rentals to use for work.) Mighetto thought she could offset the cost of the rental with a particular bonus, but the number of rides she needed to do to get that bonus seemed to keep creeping upward.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="LScOrI">
“I had six rides left, and I thought, Im sacrificing my own safety and the safety of my passenger. I just cant do it. Im exhausted. I was so infuriated that I took to the internet, looking for other people who were as outraged as I was. And there was this action the following day. I took it as a sign I needed to be there.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="lNP422">
It happened to be the night before Ubers initial public offering, and drivers around the world had organized a <a href="https://www.nytimes.com/2019/05/08/technology/uber-strike.html">day of protest</a>. Mighetto had found her people.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="OuvqVr">
“Id never, never done anything like that,” she says of the protest. “In our cars, were really isolated, and we dont have a lot of interaction with our fellow workers. So it was really wonderful to be in a community and to realize that I wasnt the only one out there that was feeling mistreated.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="biVQTD">
As Mighetto got involved in driver organizing and eventually became a member of <a href="https://www.drivers-united.org/">Rideshare Drivers United</a>, an organization of Uber and Lyft drivers fighting for legal rights and unionization, Californias Assembly Bill 5 (AB 5) was moving through the legislature. An attempt to expand protections for gig workers that predated Prop 22, the bill codified the three-part “ABC test” that the state supreme court had <a href="https://law.justia.com/cases/california/supreme-court/2018/s222732.html">recently laid out</a>, making it <a href="https://www.nytimes.com/2018/04/30/business/economy/gig-economy-ruling.html">harder</a> for gig economy companies to classify workers as independent contractors.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="YmrT5r">
The ABC test laid out three requirements that must be met in order for a worker to qualify as an independent contractor. Labor lawyer Brandon Magner <a href="https://www.dissentmagazine.org/blog/will-the-pro-act-hurt-freelancers">explains</a> it as a three-pronged test: “The A prong is that you have to be free from the companys control. The B prong says you have to be doing work that isnt central to the companys business. And the C prong says youre an independent business in that industry.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="40mxyX">
For Mighetto and other drivers, who have their rates set and rides assigned by an Uber- or Lyft-controlled app and who are carrying out the companys main — indeed, only — service, the ABC test meant that theyd be seen as employees under wage and hour laws, eligible for minimum wage and overtime protections. So Mighetto took to organizing. She even made her own flyers explaining what AB 5 would do for drivers.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="DmoM0y">
When AB 5 became law in 2019, Mighetto says, “It was a huge victory for workers.” And she began to see changes — she switched to driving for Uber after the company added new features in its app. “They would tell you where you were going all of a sudden; you were able to see how much you stood to make on a particular ride. At that point, you have the ability to choose whether or not you wanted to take that ride.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="JiZx6v">
Uber was <a href="https://www.businessinsider.com/uber-california-driver-independent-contractors-pricing-destinations-prop-22-passage-2021-4">trying to prove</a> that the drivers were truly independent. But at the same time, Mighetto says, the companies were also ramping up campaigning against the law, telling drivers that they would lose their independence if they became employees.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="JwRQaq">
When the Covid-19 pandemic hit, Mighetto was able, because of AB 5, to get unemployment benefits. She has a heart condition, and between fears for her safety and the drop in traffic, she needed to stop working. Even then, getting unemployment was complicated — the federal expansion of unemployment benefits lapsed, and she and her partner, also a driver, struggled to pay the bills as benefits waxed and waned. “We dont have basic protections,” she says. “And thats a glaring reality during a pandemic.”<strong> </strong>(A Lyft spokesperson tells Vox, “The pandemic is an unprecedented situation for all industries and communities, and our focus has been on helping keep our drivers, riders, and team members safe. Drivers do quality for Pandemic Unemployment Assistance, which we advocated for.”)
</p>
<figure class="e-image">
<img alt="A driver in a car that has a sign in the back window that reads “Uber/Lyft owes me $495,949.”" src="https://cdn.vox-cdn.com/thumbor/YZnxaHLvIyy76cQ0-ZlFtcmDsY4=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/22499243/GettyImages_1219235755.jpg"/> <cite>Mario Tama/Getty Images</cite>
<figcaption>
A “caravan protest” by Uber and Lyft drivers with Rideshare Drivers United and the Transport Workers Union of America in April 2020 called on California to enforce the AB 5 law so that they could qualify for unemployment insurance during Covid-19.
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="zsYbuD">
And then came Prop 22, an effort funded by Uber and Lyft, along with the delivery service DoorDash, which together poured <a href="https://www.nytimes.com/2020/11/04/technology/california-uber-lyft-prop-22.html">$200 million</a> into the project of exempting themselves from regulation. Prop 22 was the most expensive initiative in state history, and when it passed last fall just as the pandemic began its ferocious second wave, it carved the gig companies out of the protections of AB 5 and threw Mighetto back into limbo, with <a href="https://www.nelp.org/publication/prop-22-rolls-back-rights-women/">drastically shrunken protections</a> against sexual harassment, wondering whether shed get her unemployment and which rules the companies would change next.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="JGXEO0">
Uber <a href="https://www.businessinsider.com/uber-california-driver-independent-contractors-pricing-destinations-prop-22-passage-2021-4">yanked back</a> the control it had given drivers in the app. An Uber spokesperson tells Vox, “While these changes gave drivers more freedom than any other ride-share app provides, they also led to a third of drivers declining more than 80 percent of trip requests, making Uber very unreliable in the state. As the recovery from the pandemic picks up steam, we want to make sure riders can get a ride when they need one, and all drivers get more trips on a regular basis.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Gnc1fn">
When we spoke the first week of April, Mighetto and her partner were in Mexico because theyd effectively been homeless. “We spend every week looking to make sure that we have a roof over our heads and something to eat,” she says. “Ive been three weeks without pay. And in three weeks, I dont know where Im going to be sleeping. Were glad to hear that the weather is turning in California because were going to be going back to camping soon.”
</p>
<hr class="p-entry-hr" id="nrr1Pv"/>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="MwA1uI">
Uber and Lyft executives have long argued that <a href="https://www.forbes.com/sites/larrydownes/2013/02/06/lessons-from-uber-why-innovation-and-regulation-dont-mix/?sh=3fba1cdede94">regulations</a> hold them back. Current Uber <a href="https://economictimes.indiatimes.com/small-biz/startups/newsbuzz/big-tech-regulation-shouldnt-sweep-up-startups-uber-ceo-says/articleshow/71304432.cms?from=mdr">CEO Dara Khosrowshahi</a> told an audience at Bloombergs Global Business Forum that regulations are “tougher on startups” and could stifle innovation; previous CEO and founder Travis Kalanick once argued that he was a “<a href="https://www.theatlantic.com/technology/archive/2019/05/why-silicon-valley-loved-uber-more-everyone-else/590203/">trustbuster</a>” and the trust in question was the taxi industry. In Lyfts IPO filing, it <a href="https://www.ft.com/content/8a55de94-414e-11e9-b896-fe36ec32aece">claimed</a> “Lyft has the opportunity to deliver one of the most significant shifts to society since the advent of the car.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="0bnYE3">
But the model “is not innovative or exciting at all,” argues Veena Dubal, a professor at the University of California Hastings College of the Law, who researches gig economy work.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="7kLlb3">
To Dubal, the work conditions for Mighetto and others like her are, rather than innovations, a throwback to old models of labor exploitation like piecework and sharecropping. “Drivers are living in a scenario where they cannot predict how much theyre going to make, because how much theyre going to make is determined by algorithmic allocation, which often becomes personalized and then becomes a form of punishment,” she says. “Although [the companies] applied algorithmic science to allocating fares and rides, it is piecework that ultimately only pays when [drivers] are allocated work.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="gJSsVD">
In the 19th and 20th century, she says, immigrant women who sewed shirts at home and were paid by the shirt “at least knew how many pieces they were going to work, and they knew how much they were going to be paid per piece.” With algorithms, she says, its completely unpredictable.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="75sEZy">
The <a href="https://hbr.org/2019/08/what-people-hate-about-being-managed-by-algorithms-according-to-a-study-of-uber-drivers">algorithms</a> are designed, she explains, to “figure out what your income goal is and will push you to work longer to reach that income goal to keep more demand out there on the streets for consumers.” It recalls sharecropping because the drivers have to shoulder all the costs of car upkeep; Dubal points to a <a href="https://thehill.com/policy/technology/315172-uber-agrees-to-20-million-settlement-with-ftc">$20 million settlement</a> Uber paid in 2017 to the Federal Trade Commission after the FTC found that the company had exaggerated the money drivers could make and steered drivers into financing options for buying or leasing cars that were worse than they might have received otherwise.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="UAr4qq">
Prop 22 locks this model in place — and the companies are now looking to scale up the legislation. Theyre calling it “IC+,” for “independent contractor-plus,” and <a href="https://www.marketwatch.com/story/uber-brands-gig-companies-efforts-to-reshape-labor-laws-as-ic-11605138662">Khosrowshahi has said</a> he intends “to advocate for the IC+ model not only around the nation but also the world.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="wsysch">
In order to head off more Prop 22s, theres been talk recently from <a href="https://www.bloomberg.com/news/features/2021-02-17/gig-economy-coming-for-millions-of-u-s-jobs-after-california-s-uber-lyft-vote">companies</a>, <a href="https://uploads-ssl.webflow.com/5fa42ded15984eaa002a7ef2/5fa42ded15984e2b9d2a8061_Executive%20Summary_Clean%20Slate%20for%20Worker%20Power.pdf">researchers</a>, and some within the labor movement of a sort of grand bargain with Lyft and Uber, whereby drivers would accept that third-category worker status and, in return, be granted whats known as “sectoral bargaining.” Workers would be granted the right to organize and bargain with the companies — something that, legally, independent contractors cannot do. But Dubal and labor economist Marshall Steinbaum of the University of Utah worry that the unions have latched onto sectoral bargaining as a quick fix in a moment where the labor movement is weak, hoping that a deal can bring numbers and ward off total war.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="NWKMHI">
Sectoral bargaining, Steinbaum explains, is the idea that all workers across a given sector could be represented by a collective agreement, regardless of who their employer is. Labor historian Nelson Lichtenstein <a href="https://www.dissentmagazine.org/article/how-to-win">described it</a> in 2019 as “social bargaining with the state on behalf of all workers,” where some public institution is created to bring together stakeholders in a given industry to bargain.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="pafes4">
The gig economy, Steinbaum notes, is less a sector and more the part of the economy that is outside of labor relations. And what makes sectoral bargaining actually a terrible fit for gig companies, he explains, is that “where sectoral bargaining has a lot to offer, its exactly where you have a fragmented sector.” It works when it raises the floor for lots of different companies at the same time. In <a href="https://www.jacobinmag.com/2021/02/worker-buyouts-germany-ig-metall">Germany</a>, for instance, unions primarily negotiate with employers associations across many firms in a sector. But even there, the model has atrophied.
</p>
<figure class="e-image">
<img alt=" " src="https://cdn.vox-cdn.com/thumbor/57M1F4NalDrzTKuN-GYib3870uw=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/22499296/GettyImages_1286017879.jpg"/> <cite>Eduardo MunozAlvarez/VIEWpress/Getty Images</cite>
<figcaption>
A car marked with Ubers insignia, left, keeps pace with a yellow cab in New Yorks Times Square in November 2020. Drivers for ride-hail services are organizing with taxi workers in the state.
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="X25mJk">
With Uber and Lyft, its the opposite situation: The two companies make up, essentially, a duopoly, and have used that power to avoid any kind of regulation. Without real worker power behind that bargaining regime, he says, it would simply solidify and legalize the existing lopsided power relationship between the companies and the drivers.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="fmRhFq">
Locking the drivers into a third category — not really employees, not really independent — would wind up, Dubal says, replicating old patterns of inequality. “When they say that we need a third category of work for a new economy,” she says, “what theyre really saying is that they just dont want to have to provide these basic protections and rights and safety nets and they think that people now should be willing to survive without all of these protections that weve long come to understand as being normal and necessary.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="UVf6EE">
Its precisely the most marginalized workers that minimum wage laws were designed to protect, and according to <a href="https://drive.google.com/file/d/1jzJt3QI8yvw9dDms3eyk4LH2ejuiHhVM/view">Lyfts own economic impact report</a> for 2021, 69 percent of its drivers are members of racial or ethnic minority groups — drivers like Ouattara, who came to the US from the Ivory Coast. “Were talking about a majority people-of-color workforce,” Dubal says, “and saying that this workforce shouldnt have the same rights and benefits of other workforces of people is really a recipe for entrenched racial inequality.”
</p>
<hr class="p-entry-hr" id="NZx1NF"/>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="MKoJwD">
Prop 22 played up the idea<strong> </strong>that workers needed to be excluded from employee status in order to have flexibility, and the companies often argue that most of their drivers are part-timers doing it for a little extra on the side. According to that same Lyft economic impact report, 95 percent of drivers work fewer than 20 hours per week. But, Steinbaum notes, this argument also goes back well before the supposed innovation of the apps.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xaHUMl">
The companies will say its not <em>real </em>work — something, he says, that echoes the debates around minimum wage that trot out teenagers at part-time jobs to argue that the minimum wage shouldnt be raised. This, Steinbaum points out, is the origin of exclusion of much service and caring work from the National Labor Relations Act in the first place, and though the law has been <a href="https://www.nlrb.gov/sites/default/files/attachments/basic-page/node-1536/NLRB%2080th%20Anniversary.pdf">expanded</a> over the decades to include some of those it originally left out, others — like Mighetto and Ouattara — are still excluded.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="YmFCME">
And, Dubal adds, the companies might say that most of the drivers work just a few hours, but the reality, according to her research, is that “most of the work is done by people who are working more than full-time.” A <a href="https://www.businessinsider.com/uber-lyft-ab5-fight-reveals-dependence-full-time-drivers-2020-8">Seattle study</a>, for example, found that 55 percent of trips were done by the 33 percent of drivers who worked more than 32 hours a week. The companies contest this but are notoriously unwilling to make their data public, sharing it only with particularly chosen researchers, meaning its hard to verify study results.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="QxD0nM">
So who wants such a deal? Unions such as the Teamsters and the Service Employees International Union have signaled that theyd be open to it.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="qTJPoB">
<a href="https://www.bloomberg.com/news/features/2021-02-17/gig-economy-coming-for-millions-of-u-s-jobs-after-california-s-uber-lyft-vote">Bloombergs Josh Eidelson wrote</a>, “Unions that are trying to head off more Prop 22 scenarios and also expand their ranks will have to weigh the uncertain potential for better treatment from President Biden against the risk of losing or being cut out of the conversation entirely. If they play things wrong, traditional employment could end for millions more Americans.” Uber, he notes, has already backed a compromise with unions when it agreed to support the creation of the Independent Drivers Guild by the International Association of Machinists and Aerospace Workers.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="VndMRi">
But any dealmaking frustrates many drivers because, well, those unions dont yet represent these workers. They would, in essence, be making a decision to support legislation that workers like Mighetto themselves dont want. And such high-handed behavior is exactly what employers point to when they run anti-union campaigns. If all that workers get out of a deal is nominal union membership but no material changes to their circumstances, its only going to make them angry — at the union. “And thats damaging for the broader labor movement, not just the sector,” Dubal notes.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="JKzrqT">
Even unions sometimes seem to forget that what makes unions powerful is not dues money but people acting together to challenge unjust power. It is not the ability to file a grievance but the implicit understanding that behind that grievance lies the principle of “an injury to one is an injury to all,” which Uber and Lyft have countered with a story of individual independence and flexibility. But that story of flexibility is pitting drivers against one another; to defeat it, drivers must be united.
</p>
<hr class="p-entry-hr" id="ioJStF"/>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="NtCoPr">
Ouattara started driving for Uber<strong> </strong>in July 2016 in New York City. When New York put new rules into effect guaranteeing a <a href="https://www.vox.com/2018/12/5/18127208/new-york-uber-lyft-minimum-wage">minimum wage</a> for drivers — drivers must make at least $17.22 an hour — Ouattara says the app changed how drivers worked, exerting <a href="https://www.nytimes.com/2020/10/01/technology/uber-wages-new-york.html">more control</a> over their hours while still asserting that workers like him were independent contractors.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="AlPbOC">
Ouattara explains that he must put in a request for the time he wants to work a week in advance in order to get in the queue for a work assignment. Drivers have different ratings in the app, and the drivers who are “platinum” rated get first crack at the hours, then “gold” drivers, and so on.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="7aceqx">
Because the wage must be paid for the time the driver is active on the app, not just the time that they have a fare, Uber moved to tighten its control over New York workers to avoid paying them for idle time. “They just drastically limited the length of their queue by deciding whos in and whos out,” Steinbaum says.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="RExv1m">
Its a system not that different, though automated, from the “shape-up” that longshore workers faced for decades on the docks, where the number of workers needed would vary based on how many ships came in and what they carried. When the longshore workers on the West Coast organized with the radical International Longshore and Warehouse Union, they divided up the crews into “A-men” and “B-men”; A-men were full-timers who were assigned work first, and B-men got a crack at the work when all the A-men were employed. The difference was that the union, not the boss, decided who got which rating, and the assignments.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="7dnrkz">
With Uber, Ouattara says, there are all sorts of arbitrary rules that go into your rating. There are the ratings customers give drivers, but there are also things the app tracks, such as the drivers speed and braking. “They sent you a report based on how many times you had to brake hard. But they dont know why you brake hard. It might be because someone was about to run in front of your car and then you have to brake hard not to hit that person,” he says. “If you stop to prevent an accident, that would make you a bad driver.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ynJPEC">
The worst part, he says, is that the rules arent transparent. “Every year theres some new regulation in place to stress drivers out.”<strong> </strong>
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="wgemTY">
When the pandemic hit, Ouattara, too, stopped work for a time. He had a newborn child at home and didnt want to bring the virus home, so he applied for unemployment. But he was denied. So he reached out to the New York Taxi Workers Alliance, a labor organization that started organizing yellow cab drivers and has since expanded to include ride-hail drivers like him.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="pRM4tn">
Hed heard about NYTWA when he first became a driver as a place that drivers could go to get help, and he wound up one of the lead plaintiffs in a <a href="https://www.nytimes.com/2020/05/26/business/economy/uber-drivers-unemployment-benefits.html">lawsuit</a> demanding the state give the drivers regular unemployment insurance rather than the lower payments associated with the Pandemic Unemployment Assistance plan for independent workers. In July, a <a href="https://www.nytimes.com/2020/07/28/business/economy/lyft-uber-drivers-unemployment.html">judge</a> ruled that Ouattara and other drivers were eligible for unemployment.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="PpNNAS">
One of the reasons for the holdup, Ouattara says, was that Uber and Lyft <a href="https://www.nytimes.com/2020/05/26/business/economy/uber-drivers-unemployment-benefits.html">were not submitting</a> the required data on drivers to the state. Without that data, he and others were denied. “I did my best when I had to work at Uber,” he says. “Its not like Im going to work at different things. Its at Uber every day, 70 hours a week. How would you tell me Im not your employee when it comes to helping me out when we have a pandemic?”
</p>
<hr class="p-entry-hr" id="rt6HcK"/>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="etWhbQ">
So far, no sectoral bargaining deal<strong> </strong>has been forthcoming. In <a href="https://www.bloomberg.com/news/articles/2021-03-26/connecticut-shelves-gig-bargaining-bill-amid-union-divisions">Connecticut</a>, a proposed bill, spearheaded by the Independent Drivers Guild, was shelved when neither labor nor Uber, Lyft, or DoorDash supported it. <a href="https://www.bloomberg.com/news/articles/2021-03-18/lawmakers-look-to-spruce-up-gig-work-rather-than-replace-it">Lyft said</a> the bill would risk “the flexibility and control that drivers currently enjoy,” and a Lyft spokesperson notes to Vox, “The Connecticut Department of Labor testified against that proposal, citing its incompatibility with the [National Labor Relations Act].”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="6sWCxS">
“The companies opposed it because it was too independent even for them,” Steinbaum says. “They didnt exert total control, and I think that reflects the absence of middle ground here that such a compromise would have to be able to inhabit were it to take shape.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Qec5xr">
The bill would have established a sectoral bargaining system in which representatives of the companies and of the workers would negotiate over rules for the industry, while agreeing that the workers were not employees. And in <a href="https://www.cityandstateny.com/articles/policy/labor/after-prop-22-new-york-still-split-gig-worker-reforms.html">New York</a>, negotiations have stalled. The taxi workers union, Ouattaras organization, is advocating for something similar to AB 5 that would apply the ABC test to workers. He says, “You have to look at the control Uber has over drivers. Its absolutely control of the relationship of employee and employer. Everything youre doing is under their control.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Tem48y">
Seattle was the first city, in 2015, to attempt to put a <a href="https://www.theverge.com/2017/3/21/15000008/uber-seattle-driver-union-lawsuit-failed">bargaining regime</a> in place for ride-hail drivers. Steinbaum, who briefly consulted for the city of Seattle on litigation that followed from the attempt, describes it as “an agency that the city government recognized as the bargaining agent for ride-sharing drivers in the city, and then that agent would be empowered to essentially collectively bargain on their behalf with ride-sharing firms under the auspices of the city.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="z8vQxf">
But the companies — and the US Chamber of Commerce, a business lobbying organization — fought it, using antitrust laws (arguing that the drivers would be unfairly colluding because they were not employees). Eventually, the city shifted gears, <a href="https://www.geekwire.com/2020/uber-seattle-u-s-chamber-end-legal-dispute-union-law-city-plans-minimum-wage-drivers/">passing a law closer to New Yorks</a>, allowing drivers to be covered by minimum wage protections, and the city to establish a Driver Resolution Center to arbitrate disputes between the companies and the workers.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="RAyvt5">
Thus far, the Biden administration seems to be uninterested in federal grand bargains. Just recently, prominent <a href="https://www.latimes.com/opinion/op-ed/la-oe-weil-uber-lyft-employees-contractors-20190705-story.html">Uber critic</a> David Weil was <a href="https://news.bloomberglaw.com/daily-labor-report/biden-aims-to-pick-uber-critic-weil-for-return-as-dol-wage-chief-17">nominated</a> to resume his Obama-era post at the Labor Departments Wage and Hour Division, and the Labor Department withdrew a Trump-era rule around independent contractors that made it harder to classify drivers like Mighetto and Ouattara as employees.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="VJPg0i">
Rebecca Dixon, executive director of the National Employment Law Project, points out that in its statement, the department “skewers” the argument from gig companies around flexibility, <a href="https://public-inspection.federalregister.gov/2021-09518.pdf">saying</a>, “[F]lexible work schedules can be made available to employees as well as independent contractors, so any determination of or shift in worker classification need not affect flexibility in scheduling.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="qJCKYC">
And the president is backing the <a href="https://www.npr.org/2021/03/09/975259434/house-democrats-pass-bill-that-would-protect-worker-organizing-efforts">PRO Act</a>, which includes the ABC test for the purposes of collective bargaining (though notably not for wage and hour law, as AB 5 did). While passing anything through <a href="https://theintercept.com/2021/03/24/pro-act-labor-senate-vote-filibuster/">the Senate</a> is a tall order, labor has unsurprisingly made it a top priority to pass the act, a top-to-bottom reform of existing labor law that would, for example, include penalties for the kind of anti-union behavior demonstrated recently by Amazon in <a href="https://www.vox.com/the-highlight/22320009/amazon-bessemer-union-rwdsu-alabama">Bessemer, Alabama</a>.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Duw8aW">
With the PRO Act, Dubal thinks that both Rideshare Drivers United and the taxi workers group could potentially form a real union of ride-hail workers. Rideshare Drivers United, she says, “want to be a bargaining unit for Lyft and for Uber and the potential is 100 percent there.” Theres currently organizing taking place across the gig economy, including drivers figuring out how to “strike” on the apps; she points to <a href="https://www.vice.com/en/article/3anwdy/organized-doordash-drivers-declinenow-strategy-is-driving-up-their-pay">DoorDash drivers</a> using Facebook to organize and selectively declining cheap orders in order to push up their wages.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="e4CgYj">
Unsurprisingly, Uber and Lyft, alongside other gig companies DoorDash and Instacart, are pouring money into fighting to stop PRO. <a href="https://theintercept.com/2021/05/06/pro-act-uber-lyft-doordash-instacart-lobbying/">The Intercept</a> reported that the companies spent “at least $1,190,000 on 32 lobbyists to persuade members of Congress on the PRO Act” in 2021 so far. Uber itself spent $540,000, and its annual SEC filing notes, “If a significant number of Drivers were to become unionized and collective bargaining agreement terms were to deviate significantly from our business model, our business, financial condition, operating results and cash flows could be materially adversely affected.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xrIo5X">
A union for ride-hail drivers, Steinbaum notes, could look something like the longshore workers model. Rather than the app mysteriously assigning work and tweaking algorithms, drivers could set rules themselves while maintaining flexibility — longshore workers famously treasured the ability to work or not depending on their needs on a given day — and without giving up their power.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="MgOP1P">
The drivers could agree on seniority or another system of deciding who gets offered work first, which, Steinbaum says, “would enhance labor power because the most experienced workers would be the ones that get the work and the dynamic where the casual workers are the ones that the company wants to bring in and undermine the power of the workers on the job would be counteracted.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="mTxVFF">
The other outcome is that more industries start to move to the Uber model of on-demand workers not classified as employees, and more peoples conditions start to look like those of Mighetto and Ouattara. Shortly after Prop 22 took effect in California, delivery drivers for grocery stores under the umbrella of <a href="https://knock-la.com/vons-fires-delivery-drivers-prop-22-e899ee24ffd0/">Albertsons</a> were told they would be fired and replaced with app-based “independent” drivers. Based on what venture capitalists have signaled after Prop 22, Dubal says, “I think what is going to happen now is that theyre going to start trying to gig-ify other sectors. And thats where this stuff becomes more about the broader labor movement.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XFNgYz">
“One thing that is gratifying about [this moment] is that what I consider to be primary concerns about control, power, and autonomy are back in the forefront,” Steinbaum says. Back in 1950, when Walter Reuther, legendary head of the United Auto Workers, negotiated what became known as the “<a href="https://www.lawyersgunsmoneyblog.com/2018/05/day-labor-history-may-23-1950">Treaty of Detroit</a>,” labor agreed to stop fighting to dismantle the capitalist economy and build something else. Instead, the union agreed — and most of labor followed suit — to limit bargaining to getting their particular slice of the pie. But, Steinbaum notes, employers never really held up their end of the bargain, and in this moment theyve abandoned any commitment to their workers well-being. “Now these larger questions are back on the table.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="IM3aem">
To Ouattara, the pandemic was a clarifying moment, proving that Uber wasnt interested in helping the drivers. And to Mighetto, Prop 22 undid 100 years of progress. “It rolls back the New Deal; it rolls back all the work thats been done to get us workers compensation. For me, it rolls back the Me Too movement.” The only choice, she says, is to keep fighting, because the amount the companies spent on Prop 22 is a reminder that they have no intention of changing their model. “If you think about it, $200 million is a small investment if you plan to continue exploiting people indefinitely.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="hjol1G">
<em>Sarah Jaffe is an independent journalist and the author of </em>Work Wont Love You Back: How Devotion to Our Jobs Keeps Us Exploited, Exhausted, and Alone<em>. Her work has appeared in the New York Times, the Nation, the Washington Post, the Atlantic, and elsewhere.</em>
</p>
<div>
<div id="plmVfu">
<div>
</div>
</div>
</div></li>
</ul>
<h1 data-aos="fade-right" id="from-the-hindu-sports">From The Hindu: Sports</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Bereaved Veda thanks BCCI, Jay Shah for extending support</strong> - The middle-order India batter lost her mother and elder sister to COVID-19.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>We Are The People: UEFA EURO 2020 anthem is out</strong> - Twenty-five year-old Dutch DJ Martin Garrix ropes in legendary U2 bigwigs Bono and The Edge for the song</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>COVID-19 | Wriddhiman Saha recovers, fit for England tour</strong> - The wicketkeeper-batsman reached his home in Kolkata after completing over a fortnight-long quarantine at a Delhi hotel</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Delhi Police announces ₹1 lakh reward for info on Sushil Kumar</strong> - The two-time Olympic medallist is wanted in connection with a brawl that led to the death of a wrestler in New Delhi.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Me, Rafa and Roger are reinventing the Next Gen: Djokovic</strong> - World No.1 Novak Djokovic took a swipe at all the talk about the younger generation of tennis players, saying rival Rafael Nadal and himself were the</p></li>
</ul>
<h1 data-aos="fade-right" id="from-the-hindu-national-news">From The Hindu: National News</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Severe Cyclonic Storm Tauktae to weaken into Depression in next 12 hours: INCOIS-IMD</strong> - Tidal wave above astronomical tide is likely to inundate coastal areas in the next three hours</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Coronavirus | Daily COVID-19 recoveries more than 4 lakh for first time in country</strong> - Average daily recovery of more than 3,55,944 cases has been recorded in the last 14 days, the Health Ministry said</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>COVID-19: CBSE extends deadline till June 30 for schools to tabulate marks for class 10</strong> - “CBSE accords highest priority to safety and health of teachers.”</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Floodplain fishing continues unabated in Kerala</strong> - It is a serious threat to survival of many inland fishes, say experts</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>40 U.K. docs of Mysuru origin join telemedicine initiative</strong> - Details of COVID-19 Mitra shared with Centre, says DC, after participating in PMs video conference on pandemic situation</p></li>
</ul>
<h1 data-aos="fade-right" id="from-bbc-europe">From BBC: Europe</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Migrants reach Spains Ceuta enclave in record numbers</strong> - At least 6,000 people arrive in Ceuta from Morocco, many swimming in using rubber rings and rafts.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Lost village emerges from Italian lake</strong> - Repair works at a reservoir in Italy have revealed the remains of a village submerged for decades.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Belarus raids top news site in widening crackdown</strong> - Major independent site Tut.by goes offline and its editors home is raided.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Russia spy chief suggests West behind SolarWinds cyber-attack</strong> - Sergei Naryshkin speaks to the BBC in a rare interview about 2020s SolarWinds cyber-attack in the US.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>RHS Bridgewater: Europes biggest horticultural project opens</strong> - The new 154-acre RHS Bridgewater opens in Salford a year later than planned, due to the pandemic.</p></li>
</ul>
<h1 data-aos="fade-right" id="from-ars-technica">From Ars Technica</h1>
<ul>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>McLaren goes with a clean-sheet chassis and engine for Artura supercar</strong> - Theres a new carbon-fiber monocoque and a 120-degree V6. - <a href="https://arstechnica.com/?p=1765657">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Demeo is the best multiplayer, virtual-reality D&amp;D clone ever made</strong> - Issues aside, it already feels like sharing a real-life dice-and-minis table with friends. - <a href="https://arstechnica.com/?p=1763983">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Biden pledges to share 20 million COVID-19 vaccine doses with the world</strong> - The 20 million will be in addition to 60 million AstraZeneca doses already pledged. - <a href="https://arstechnica.com/?p=1765579">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Apples M1 is a fast CPU—but M1 Macs feel even faster due to QoS</strong> - Howard Oakley did an excellent deep dive on M1 scheduling and performance. - <a href="https://arstechnica.com/?p=1765494">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Apple Music subscribers will get lossless and spatial audio for free next month</strong> - New features will launch with iOS 14.6, macOS 11.4 in June. - <a href="https://arstechnica.com/?p=1765499">link</a></p></li>
</ul>
<h1 data-aos="fade-right" id="from-jokes-subreddit">From Jokes Subreddit</h1>
<ul>
<li><strong>A frustrated wife goes to the doctor (long)</strong> - <!-- SC_OFF -->
<div class="md">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Doctor, you have to help me. Ive been married 30 years to my husband and I feel hes lost all interest in me. You know, phisically speaking. He barely looks at me, let alone have sex with me. Oh, I really miss the good old times where we had wonderful sex multiple times a week, there must be something you can do to help me…”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Well, its not very ethical, but theres this experimental drug we need to test” the doctor takes a vial from a drawer “this is a very potent aphrodisiac. Just one drop in a glass of water is enough to awaken the libido of a dying man. When you feel its a special night and you want to have sex with your husband, try and pour one drop in his glass, and I can guarantee that you will see a new life in him”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Oh thank you doctor, thank you so much. Tomorrow its our anniversary, what better night to try it out?”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Two days pass. The morning after the fated night, the woman goes back to the doctor. She appears disheveled, barely being able to walk.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Wh-what happened?” Asks the doctor, visibly worried
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Oh, doctor, I feel so sad… Yesterday, while we were having dinner, I waited for him to go to the toilet and, as you suggested, I hastily poured one drop of the drug in his water glass. But then I thought: what if this is not enough? Its been a LONG time since hes shown any passion towards me. So I poured another drop.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Wait, two drops?? But its dangerous, we dont know what can happen if more than one drop is used!”
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“But then I felt so insecure, what if he doesnt like my body anymore? Is two drops really enough? I panicked, and I emptied the whole vial in the glass of water.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“……”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“He came back from the toilet, sat down and took a good sip from the glass. He froze, eyes wide. The glass fell from his hand. He stared at me like a predator stares at its prey. Then it happened. He violently threw away everything that was on the table, snorting and roaring. Grabbed me, slammed me on the bare table, tore my clothes as well as his and proceeded to have his way with me, making animal sounds I had never heard him make.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Im so sorry for you, it must have been terrible”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Oh no, doctor. It was the best sex Ive ever had in 30 years of marriage. I orgasmed multiple times in a matter of minutes, I saw a rough, untamed side of my husband that I thought didnt exist.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Wait, you enjoyed it? Then why did you say you were sad?”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Well, it was our favourite restaurant, I doubt well be able to show our faces again there…”
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<!-- SC_ON -->
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/PurplMaster"> /u/PurplMaster </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/nevr4o/a_frustrated_wife_goes_to_the_doctor_long/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/nevr4o/a_frustrated_wife_goes_to_the_doctor_long/">[comments]</a></span></p></li>
<li><strong>I tell dad jokes all the time even though Im not actually a dad</strong> - <!-- SC_OFF -->
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Im a faux pa.
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/nita1568"> /u/nita1568 </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/nedrj4/i_tell_dad_jokes_all_the_time_even_though_im_not/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/nedrj4/i_tell_dad_jokes_all_the_time_even_though_im_not/">[comments]</a></span></p></li>
<li><strong>Guy : Doctor, my Girlfriend is pregnant but we always use protection and the rubber never broke. How is it possible?</strong> - <!-- SC_OFF -->
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Doctor : Let me tell you a story: "There was once a Hunter who always carried a gun wherever he went. One day he took out his Umbrella instead of his Gun and went out. A Lion suddenly jumped infront of him. In order to scare the Lion, the Hunter used the Umbrella like a Gun, and shot the Lion, then it died!
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Guy : Nonsense! Someone else must have shot the Lion..
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Doctor : Good! You understood the story. Next patient please..
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<!-- SC_ON -->
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/Genius_Mate"> /u/Genius_Mate </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/nef1f7/guy_doctor_my_girlfriend_is_pregnant_but_we/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/nef1f7/guy_doctor_my_girlfriend_is_pregnant_but_we/">[comments]</a></span></p></li>
<li><strong>A mother in law said to her sons wife when their baby was born:</strong> - <!-- SC_OFF -->
<div class="md">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“I dont mean to be rude but he doesnt look anything like my son.” The daughter-in-law lifted her skirt and said: “I dont mean to be rude either, but this is a pussy, not a fucking photo-copier.”
</p>
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/My_Balls_Itch_123"> /u/My_Balls_Itch_123 </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/nf7g4z/a_mother_in_law_said_to_her_sons_wife_when_their/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/nf7g4z/a_mother_in_law_said_to_her_sons_wife_when_their/">[comments]</a></span></p></li>
<li><strong>Who swore the most in star wars?</strong> - <!-- SC_OFF -->
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
R2-D2, they beeped out every word he said
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/itsaveryshittyname"> /u/itsaveryshittyname </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/necqxe/who_swore_the_most_in_star_wars/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/necqxe/who_swore_the_most_in_star_wars/">[comments]</a></span></p></li>
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