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<title>01 May, 2022</title>
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<title>Covid-19 Sentry</title><meta content="width=device-width, initial-scale=1.0" name="viewport"/><link href="styles/simple.css" rel="stylesheet"/><link href="../styles/simple.css" rel="stylesheet"/><link href="https://unpkg.com/aos@2.3.1/dist/aos.css" rel="stylesheet"/><script src="https://unpkg.com/aos@2.3.1/dist/aos.js"></script></head>
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<h1 data-aos="fade-down" id="covid-19-sentry">Covid-19 Sentry</h1>
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<h1 data-aos="fade-right" data-aos-anchor-placement="top-bottom" id="contents">Contents</h1>
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<ul>
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<li><a href="#from-preprints">From Preprints</a></li>
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<li><a href="#from-clinical-trials">From Clinical Trials</a></li>
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<li><a href="#from-pubmed">From PubMed</a></li>
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<li><a href="#from-patent-search">From Patent Search</a></li>
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<h1 data-aos="fade-right" id="from-preprints">From Preprints</h1>
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<li><strong>Long Term Virucidal Activity of Rosin Soap on Surfaces</strong> -
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Microbiocidal products for decontaminating both animate and inanimate surfaces that may act as vectors for disease transmission are a well-established method for inactivating viruses of clinical significance. There are a wide variety of such microbiocidal products that can be purchased commercially, many with different active ingredients. We have recently shown that Rosin soap (derived from Tall Oil that has been produced by trees) is a highly effective virucidal product against enveloped viruses like influenza A virus and SARS-CoV-2 when tested in solution. Here we further demonstrate that Rosin soap retains its virucidal activity against influenza A virus and SARS-CoV-2 when applied to surfaces, such as plastic, glass and steel, either before or after virus inoculation. The virucidal activity extended out to seven days post administration. Together, our results show the potential for Rosin soap-based disinfectants to be used as a surface coating to protect against clinically relevant enveloped viruses, such as influenza viruses and coronaviruses.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2022.04.29.490117v1" target="_blank">Long Term Virucidal Activity of Rosin Soap on Surfaces</a>
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</div></li>
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<li><strong>Analysis of Stock Trading Transactions on the Secondary Market</strong> -
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This study aims to analyze the trading of stock transactions on the secondary market in Indonesia during the compared October 2018 to 2021; by examining the stock trading on the IDX, the results of the shares traded in the October 2018-2021 period experienced price fluctuations with a tendency to increase significantly. With the dynamics of the changing global and national economic environment, as well as stock trading transactions during the four years, the volume of transactions on the IDX increased, despite the COVID-19 outbreak, natural disasters such as flash floods, national economic growth experiencing a sharp decline and policies the government in normalizing the economy such as the United States (USA) will implement a tapering policy, so that this condition affects the decisions of IDX investors in buying and selling shares.
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<div class="article-link article-html-link">
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🖺 Full Text HTML: <a href="https://osf.io/95dcr/" target="_blank">Analysis of Stock Trading Transactions on the Secondary Market</a>
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</div></li>
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<li><strong>Global upsurge in violence against women during COVID-19: A rapid review of evidence</strong> -
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In any disaster or climactic events, reports on violence against women (VAW) often substantially increase. Although the ongoing COVID-19 pandemic shares some key similarities with previous catastrophes, it also presents a unique paradox for women. A number of measures taken to contain the spread of coronavirus, such as quarantine and isolation, increase the risk of VAW. This article reviews literature on disaster-related VAW surges and accumulates the recent anecdotal reports from a number of countries in different continents to demonstrate an alarming increase in all forms of VAW due to containment measures. The article identifies causal factors behind the upsurge in VAW during this pandemic and discusses specific measures to be taken urgently to support the victims as well as prevent and reduce the occurrence of violence.
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</div>
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<div class="article-link article-html-link">
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🖺 Full Text HTML: <a href="https://osf.io/preprints/socarxiv/ey9hz/" target="_blank">Global upsurge in violence against women during COVID-19: A rapid review of evidence</a>
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</div></li>
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<li><strong>Fifteen Years of India’s NREGA: Employer of the Last Resort?</strong> -
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For the last decade, India’s National Rural Employment Guarantee Act (NREGA, 2005) has been the world’s largest public works programme. This legal entitlement provided employment to 28 percent of rural Indian households in 2019-20. After the COVID-19 pandemic, NREGA is increasingly emerging as an invaluable employer of the last resort. However, longitudinal data of its implementation in the last fifteen years reveals distinctive trends. On the one hand, since inception NREGA has rendered greater benefit to women and marginalised communities. But on the other, since 2014, the right-wing Bharatiya Janata Party (BJP)-led government has reduced NREGA coverage compared to its implementation during the previous Indian National Congress (INC)-led United Progressive Alliance (UPA) coalition which had enacted the legislation. Nevertheless, in light of the pandemic and based on from international experiences, there is an urgent need for expansion of the employment guarantee.
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</div>
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<div class="article-link article-html-link">
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🖺 Full Text HTML: <a href="https://osf.io/preprints/socarxiv/92un7/" target="_blank">Fifteen Years of India’s NREGA: Employer of the Last Resort?</a>
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</div></li>
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<li><strong>Machine learning in a time of COVID-19 – Can machine learning support Community Health Workers (CHWs) in low and middle income countries (LMICs) in the new normal?</strong> -
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Now, in the time of COVID-19, such measures are even more important. If the promises held out for the universal acceptability and efficacy of ML and person-centric health care are to be realised, ML must be affordable at a grassroots level in LMICs. More collaboration and co-design involving mobile health developers, mobile telecoms companies, governments, trans-national organisations and non-governmental organisations (NGOs) could result in affordable generic open-source templates. Most importantly, such a collaboration needs to be done in parallel with paying CHWs a living wage. Achieving such a goal would remove the need for any CHW ever having to resort to prostitution to purchase medicines in order to treat their patients.
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</div>
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<div class="article-link article-html-link">
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🖺 Full Text HTML: <a href="https://osf.io/eknj9/" target="_blank">Machine learning in a time of COVID-19 – Can machine learning support Community Health Workers (CHWs) in low and middle income countries (LMICs) in the new normal?</a>
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</div></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Predicting self-harm and suicide ideation during the COVID-19 pandemic in Indonesia: A nationwide survey report</strong> -
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Background: It is estimated that 77.0% of suicide cases occurred in low-and-middle-income countries (LMICs), which would increase because of the COVID-19 pandemic and socioeconomic inequity. However, there is lack of reports on this topic from LMICs, especially during the pandemic. Therefore, this nationwide study aimed to explore self-harm and suicide ideation and its predictive variables during the pandemic in Indonesia as a MIC with the highest COVID-19 fatality rate in Asia. Methods: Non-random sampling online survey was conducted nationwide between 25 May and 16 June</div></li>
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<ol start="2021" type="1">
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<li>The collected data were demographic variables (i.e. age group), loneliness from social isolation using The UCLA Loneliness Scale Six Items (ULS-6), and self-harm and suicide ideation using item 9 of The Patient Health Questionnaire-9 (PHQ-9). Predictive model was analyzed using hierarchical logistic regression. Results: A total of 5,211 participants from all 34 provinces in Indonesia completed the survey. Among 39.3% of them reported self-harm and suicide ideation during the pandemic, which significantly correlated with loneliness. The predictive variables associated with the likelihood of self-harm and suicide ideation were age, residence, job, religion, sex-gender, sexual orientation, HIV status, disability status, and loneliness. The predictive model showed a significant goodness-of-fit to the observed data (x2(15) = 1,803.46, p<.001), RN2 = .40. Conclusion: Four out of 10 Indonesians experienced self-harm and suicide ideation during the COVID-19 pandemic, particularly people within the age range of 18-24, living in the Java Island, unemployed/student/retired and freelancer, women, members of minority and marginalized communities, and experience of loneliness during the pandemic.
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<div class="article-link article-html-link">
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🖺 Full Text HTML: <a href="https://psyarxiv.com/f3c8w/" target="_blank">Predicting self-harm and suicide ideation during the COVID-19 pandemic in Indonesia: A nationwide survey report</a>
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</div></li>
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</ol>
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<ul>
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<li><strong>Immediate myeloid depot for SARS-CoV-2 in the human lung</strong> -
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In the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, considerable focus has been placed on a model of viral entry into host epithelial populations, with a separate focus upon the responding immune system dysfunction that exacerbates or causes disease. We developed a precision-cut lung slice model to investigate very early host-viral pathogenesis and found that SARS-CoV-2 had a rapid and specific tropism for myeloid populations in the human lung. Infection of alveolar macrophages was partially dependent upon their expression of ACE2 and the infections were productive for amplifying virus, both findings which were in contrast with their neutralization of another pandemic virus, Influenza A virus (IAV). Compared to IAV, SARS-CoV-2 was extremely poor at inducing interferon-stimulated genes in infected myeloid cells, providing a window of opportunity for modest titers to amplify within these cells. Endotracheal aspirate samples from humans with COVID-19 confirmed the lung slice findings, revealing a persistent myeloid depot. In the early phase of SARS-CoV-2 infection, myeloid cells may provide a safe harbor for the virus with minimal immune stimulatory cues being generated, resulting in effective viral colonization and quenching of the immune system.
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<div class="article-link article-html-link">
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2022.04.28.489942v1" target="_blank">Immediate myeloid depot for SARS- CoV-2 in the human lung</a>
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</div></li>
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<li><strong>Occupational differences in SARS-CoV-2 infection: Analysis of the UK ONS Coronavirus (COVID-19) Infection Survey</strong> -
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Background Considerable concern remains about how occupational SARS-CoV-2 risk has evolved during the COVID-19 pandemic. We aimed to ascertain which occupations had the greatest risk of SARS-CoV-2 infection and explore how relative differences varied over the pandemic. Methods Analysis of cohort data from the UK Office of National Statistics Coronavirus (COVID-19) Infection Survey from April 2020 to November 2021. This survey is designed to be representative of the UK population and uses regular PCR testing. Cox and multilevel logistic regression to compare SARS-CoV-2 infection between occupational/sector groups, overall and by four time periods with interactions, adjusted for age, sex, ethnicity, deprivation, region, household size, urban/rural neighbourhood and current health conditions. Results Based on 3,910,311 observations from 312,304 working age adults, elevated risks of infection can be seen overall for social care (HR 1.14; 95% CI 1.04 to 1.24), education (HR 1.31; 95% CI 1.23 to 1.39), bus and coach drivers (1.43; 95% CI 1.03 to 1.97) and police and protective services (HR 1.45; 95% CI 1.29 to 1.62) when compared to non-essential workers. By time period, relative differences were more pronounced early in the pandemic. For healthcare elevated odds in the early waves switched to a reduction in the later stages. Education saw raises after the initial lockdown and this has persisted. Adjustment for covariates made very little difference to effect estimates. Conclusions Elevated risks among healthcare workers have diminished over time but education workers have had persistently higher risks. Long-term mitigation measures in certain workplaces may be warranted.
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</p>
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<div class="article-link article-html-link">
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🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.04.28.22273177v1" target="_blank">Occupational differences in SARS-CoV-2 infection: Analysis of the UK ONS Coronavirus (COVID-19) Infection Survey</a>
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</div></li>
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<li><strong>A bacteriophage-based, highly efficacious, needle and adjuvant-free, mucosal COVID-19 vaccine</strong> -
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<div>
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The authorized mRNA- and adenovirus-based SARS-CoV-2 vaccines are intramuscularly injected and effective in preventing COVID-19, but do not induce efficient mucosal immunity, or prevent viral transmission. We developed a bacteriophage T4-based, multicomponent, needle and adjuvant-free, mucosal vaccine by engineering spike trimers on capsid exterior and nucleocapsid protein in the interior. Intranasal administration of T4-COVID vaccine induced higher virus neutralization antibody titers against multiple variants, balanced Th1/Th2 antibody and cytokine responses, stronger CD4+ and CD8+ T cell immunity, and higher secretory IgA titers in sera and bronchoalveolar lavage with no effect on the gut microbiota, compared to vaccination of mice intramuscularly. The vaccine is stable at ambient temperature, induces apparent sterilizing immunity, and provides complete protection against original SARS-CoV-2 strain and its Delta variant with minimal lung histopathology. This mucosal vaccine is an excellent candidate for boosting immunity of immunized and/or as a second-generation vaccine for the unimmunized population.
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</div>
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<div class="article-link article- html-link">
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2022.04.28.489809v1" target="_blank">A bacteriophage-based, highly efficacious, needle and adjuvant-free, mucosal COVID-19 vaccine</a>
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</div></li>
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<li><strong>Systematic analysis of alternative splicing in time course data using Spycone</strong> -
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<div>
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During disease progression or organism development, alternative splicing (AS) may lead to isoform switches (IS) that demonstrate similar temporal patterns and reflect the AS co-regulation of such genes. Tools for dynamic process analysis usually neglect AS. Here we propose Spycone (https://github.com/yollct/spycone), a splicing-aware framework for time course data analysis. Spycone exploits a novel IS detection algorithm and offers downstream analysis such as network and gene set enrichment. We demonstrate the performance of Spycone using simulated and real-world data of SARS- CoV-2 infection.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2022.04.28.489857v1" target="_blank">Systematic analysis of alternative splicing in time course data using Spycone</a>
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</div></li>
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<li><strong>A Novel Y-Shaped, S-O-N-O-S-Bridged Crosslink between Three Residues C22, C44, and K61 Is a Redox Switch of the SARS-CoV-2 Main Protease</strong> -
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As the COVID-19 pathogen, SARS-CoV-2 relies on its main protease (MPro) for pathogenesis and replication. During the crystallographic analyses of MPro crystals that were exposed to the air, a uniquely Y-shaped, S-O-N-O-S-bridged posttranslational crosslink that connects three residues C22, C44, and K61 at their side chains was frequently observed. As a novel posttranslational modification, this crosslink serves as a redox switch to regulate the catalytic activity of MPro, a demonstrated drug target of COVID-19. The formation of this linkage leads to a much more opened active site that can be potentially targeted for the development of novel SARS-CoV-2 antivirals. The inactivation of MPro by this crosslink indicates that small molecules that lock MPro in the crosslinked form can be potentially used with other active site-targeting molecules such as paxlovid for synergistic effects in inhibiting the SARS-CoV-2 viral replication. Therefore, this new finding reveals a unique aspect of the SARS-CoV-2 pathogenesis and is potentially paradigm-shifting in our current understanding of the function of MPro and the development of its inhibitors as COVID-19 antivirals.
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</div>
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2022.04.29.490044v1" target="_blank">A Novel Y-Shaped, S-O-N-O-S-Bridged Crosslink between Three Residues C22, C44, and K61 Is a Redox Switch of the SARS-CoV-2 Main Protease</a>
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<li><strong>A Solution to the Kermack and McKendrick Integro-Differential Equations</strong> -
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In this manuscript, we derive a closed form solution to the full Kermack and McKendrick integro-differential equations (Kermack and McKendrick 1927) which we call the KMES. The KMES can be cast in the form of a step function response to the input of new infections; and that response is the time series of the total infections. We demonstrate the veracity of the KMES using independent data from the Covid 19 pandemic and derive many previously unknown and useful analytical expressions for diagnosing and managing an epidemic. These include new expressions for the viral load, the final size, the effective reproduction number, and the time to the peak in infections. Since the publication of the Kermack and McKendrick seminal paper (1927), thousands of authors have utilized the Susceptible, Infected, and Recovered (SIR) approximations; expressions which are putatively derived from the integro-differential equations, to model epidemic dynamics. Implicit in the use of the SIR approximation are the beliefs that there is no closed form solution to the more complex integro-differential equations, that the approximation adequately reproduces the dynamics of the integro-differential equations, and that herd immunity always exists. However, as we explicate in this manuscript, the KMES demonstrates that the SIR models are not adequate representations of the integro-differential equations, and herd immunity is not guaranteed. Our conclusion is that the KMES obsoletes the need for the SIR approximations; and provides a new level of understanding of epidemic dynamics.
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</p>
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🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.04.28.22274442v1" target="_blank">A Solution to the Kermack and McKendrick Integro-Differential Equations</a>
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</div></li>
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<li><strong>Protection against Omicron re-infection conferred by prior heterologous SARS-CoV-2 infection, with and without mRNA vaccination</strong> -
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Importance. Omicron is phylogenetically- and antigenically-distinct from earlier SARS-CoV-2 variants and the original vaccine strain. Protection conferred by prior SARS-CoV-2 infection against Omicron re-infection, and the added value of vaccination, require quantification. Objective. To estimate protection against Omicron re-infection and hospitalization conferred by prior heterologous SARS-CoV-2 (non-Omicron) infection and/or up to three doses of (ancestral, Wuhan-like) mRNA vaccine. Design. Test-negative study between December 26 (epi-week 52), 2021 and March 12 (epi-week 10), 2022. Setting. Population-based, province of Quebec, Canada Participants. Community-dwelling ≥12-year- olds tested for SARS-CoV-2. Exposures. Prior laboratory-confirmed infection with/without mRNA vaccination. Outcomes. Laboratory-confirmed SARS-CoV-2 re-infection and hospitalization, presumed Omicron by genomic surveillance. The odds of prior non-Omicron infection with/without vaccination were compared among Omicron cases/hospitalizations versus test- negative controls (single randomly-selected per individual). Adjusted odds ratios controlled for age, sex, testing- indication and epi-week. Analyses were stratified by severity and time since last non-Omicron infection or vaccine dose. Results. Without vaccination, prior non-Omicron infection reduced the Omicron re-infection risk by 44% (95%CI:38-48), decreasing from 66% (95%CI:57-73) at 3-5 months to 35% (95%CI:21-47) at 9-11 months post-infection and <30% thereafter. The more severe the prior infection, the greater the risk reduction: 8% (95%CI:17-28), 43% (95%CI:37-49) and 68% (95%CI:51-80) for prior asymptomatic, symptomatic ambulatory or hospitalized infections. mRNA vaccine effectiveness against Omicron infection was consistently significantly higher among previously-infected vs. non-infected individuals at 65% (95%CI:63-67) vs. 20% (95%CI:16-24) for one-dose; 68% (95%CI:67-70) vs. 42% (95%CI:41-44) for two doses; and 83% (95%CI:81-84) vs. 73% (95%CI:72-73) for three doses. Infection-induced protection against Omicron hospitalization was 81% (95%CI: 66-89) increasing to 86% (95%CI:77-99) with one, 94% (95%CI:91-96) with two and 97%(95%CI:94-99) with three mRNA vaccine doses. Two-dose effectiveness against hospitalization among previously-infected individuals did not wane across 11 months and did not significantly differ from three-dose effectiveness despite longer follow-up (median 158 and 27 days, respectively). Conclusions and relevance. Prior heterologous SARS-CoV-2 infection provided substantial and sustained protection against Omicron hospitalization, greatest among those also vaccinated. In the context of program goals to prevent severe outcomes and preserve healthcare system capacity, >2 doses of ancestral Wuhan-like vaccine may be of marginal incremental value to previously-infected individuals.
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🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.04.29.22274455v1" target="_blank">Protection against Omicron re-infection conferred by prior heterologous SARS-CoV-2 infection, with and without mRNA vaccination</a>
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</div></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>PCR Testing in the UK During the SARS-CoV-2 Pandemic - Evidence from FOI Requests</strong> -
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Polymerase Chain Reaction (“PCR”) tests have been used to identify cases of COVID-19 during the course of the pandemic. Notably, PCR alone cannot differentiate between the presence of whole viruses (which can be transmitted and infect individuals) and small fragments of genetic material that are not infectious. A feature of PCR known as the cycle threshold (Ct) can be used to discriminate between these states, but the relationship between Ct and infectiousness is still poorly understood. This well-known limitation of the test compromises the identification of cases and their trends, and consequently those measures to interrupt transmission (such as isolation) that are undertaken on the basis of reliably identifying infectious individuals. Here, we interrogate the public authorities9 understanding of PCR testing for SARS-CoV-2 in the UK by accessing Freedom of Information requests submitted in 2020-21.We searched WhatDoTheyKnow and found 300 FOI requests, from over 150 individuals. We grouped their questions into four themes addressing the number of tests in use, the reporting of cycle thresholds (9Ct9), the Ct values themselves, and the accuracy of tests. The number of validated tests in use in the UK is currently not clear: In FOI responses, Public Health England (PHE) report it may be “80” or “85”. However, European regulations suggest there could be over 400 different CE marked tests available on the market and available for use. Laboratories have a statutory duty to report positive cases to PHE, but they do not have to advise which tests they are using nor submit Ct values. Only two FOI responses provided answers on Ct values, indicating that in a set time span, 24-38% of the Ct values were over 30. The most common FOI asked if there was a cycle threshold for positivity. In those that responded, the Ct for a positive result varied from 30 to 45. We found limited information on the technical accuracy of the tests. Several responses stated there is no 9static9, 9specific9 or 9standard9 cycle threshold. The current system requires significant changes to ensure it offers accurate diagnostic data to enable effective clinical management of SARS-CoV-2. PCR is an important and powerful tool, but its systematic misuse and misreporting risk undermining its usefulness and credibility.
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🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.04.28.22274341v1" target="_blank">PCR Testing in the UK During the SARS-CoV-2 Pandemic - Evidence from FOI Requests</a>
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<li><strong>Understanding Definitions and Reporting of Deaths Attributed to COVID-19 in the UK - Evidence from FOI Requests</strong> -
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Death is a widely used outcome to assess the severity of pandemics. Accuracy in assigning the cause of death is of vital importance to define the impact of the agent, monitor its evolution, and compare its threat with those of other agents. Throughout the COVID-19 pandemic, there has been widespread reporting of aggregate death data with little attention paid to the accuracy of the assignment of causation. We aimed to analyse public authorities9 understanding of the assignment of cause of deaths during the SARS-CoV-2 pandemic in the UK by accessing Freedom of Information requests posed in three periods in 2020-21. By public authorities, we mean NHS Health Trusts, laboratories, and government agencies such as Public Health England and the Department of Health and Social Care. We searched WhatDoTheyKnow using the terms “covid and death”. We excluded those requests to bodies that cannot provide an answer (e.g. Councils) and those dealing with the effects of vaccines. We grouped questions into themes addressing the definitions and causes of death relevant to the pandemic. We looked at the responses to the questions of the definition of cause of death, the accuracy of the attribution, the role of other pre-existing pathologies and how these were reported and quantified. We found 800 requests from over 90 individuals. There was no consistency in the definition of cause of death or contributory cause of death across national bodies and in different bodies within the same nation. Nursing home providers, as well as medical practitioners, can assign a cause of death according to the Care Quality Commission. Post- mortem examinations were uncommon, the ONS did not incorporate their results in the summary of deaths by cause during the pandemic period. The meaning of the words “test” or “swab” was never clarified by any of the respondents. In care homes in England 1,304 out of 17,264 COVID-19 (7.6%, range 0% to 63%) mentioned COVID-19 in the absence of contributory or other factors in the death certificate, making it impossible to ascertain a chain of causality. The inconsistencies already noted hinder the ascertainment of the role of each factor leading to death and the quantification of the importance of infection. Some responses indicate that SARS-CoV-2 negative individuals or those whose death was not caused by COVID-19 were classified as “COVID-19 deaths”. We found 14 different ways of attributing the causes of death mentioned by respondents. The overall lack of consistency has confused the public and likely led to erroneous conclusions. We are unable to separate the effects on deaths of SARS-CoV-2 from those of human interventions. A coherent process based on consistent definitions across the devolved nations is required. Furthermore, to enhance the accuracy of causation in pandemics a subset of deaths should be verified using autopsies with full medical documentation.
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</p>
|
||||
</div>
|
||||
<div class="article-link article-html-link">
|
||||
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.04.28.22274344v1" target="_blank">Understanding Definitions and Reporting of Deaths Attributed to COVID-19 in the UK - Evidence from FOI Requests</a>
|
||||
</div></li>
|
||||
</ul>
|
||||
<h1 data-aos="fade-right" id="from-clinical-trials">From Clinical Trials</h1>
|
||||
<ul>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Clinical Performance Evaluation of the Bio-Self™ COVID-19 Antigen Home Test</strong> - <b>Condition</b>: COVID-19<br/><b>Interventions</b>: Device: Bio-Self COVID-19 Antigen Home Test; Device: Standard of Care COVID-19 Test; Diagnostic Test: RT-PCR Test<br/><b>Sponsors</b>: BioTeke USA, LLC; CSSi Life Sciences<br/><b>Not yet recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Immunogenicity and Safety of Fractional Booster Dose of COVID-19 Vaccines Available for Use in Pakistan/Brazil: A Phase 4 Dose-optimizing Trial</strong> - <b>Condition</b>: COVID-19<br/><b>Interventions</b>: Biological: Sinovac; Biological: AZD1222; Biological: BNT162b2<br/><b>Sponsors</b>: Albert B. Sabin Vaccine Institute; Aga Khan University; Oswaldo Cruz Foundation; Stanford University<br/><b>Not yet recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Study to Evaluate the Immunogenicity and Safety of a Recombinant Protein COVID-19 Vaccine as a Booster Dose in Population Aged 12-17 Years</strong> - <b>Conditions</b>: COVID-19; SARS-CoV-2 Infection<br/><b>Interventions</b>: Biological: SCTV01E; Biological: mRNA-1273<br/><b>Sponsor</b>: Sinocelltech Ltd.<br/><b>Not yet recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A First-In-Human Phase 1b Study of AmnioPul-02 in COVID-19</strong> - <b>Condition</b>: COVID-19<br/><b>Intervention</b>: Drug: AmnioPul-02<br/><b>Sponsor</b>: Amniotics AB<br/><b>Not yet recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Study of COVID-19 mRNA Vaccine (SYS6006) in Chinese Healthy Older Adults.</strong> - <b>Condition</b>: COVID-19<br/><b>Interventions</b>: Biological: 20 μg dose of SYS6006; Biological: 30 μg dose of SYS6006; Biological: 50 μg dose of SYS6006; Drug: Placebo<br/><b>Sponsor</b>: <br/>
|
||||
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.<br/><b>Recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Safety, Reactogenicity, and Immunogenicity Study of a Lyophilized COVID-19 mRNA Vaccine</strong> - <b>Condition</b>: Covid19<br/><b>Interventions</b>: Biological: A Lyophilized COVID-19 mRNA Vaccine; Biological: Placebo<br/><b>Sponsor</b>: Jiangsu Rec-Biotechnology Co., Ltd.<br/><b>Not yet recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Study of COVID-19 mRNA Vaccine (SYS6006) in Chinese Healthy Adults Aged 18 -59 Years.</strong> - <b>Condition</b>: COVID-19<br/><b>Interventions</b>: Biological: 20 μg dose of SYS6006; Biological: 30 μg dose of SYS6006; Biological: 50 μg dose of SYS6006; Drug: Placebo<br/><b>Sponsor</b>: <br/>
|
||||
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.<br/><b>Recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Phase 2b/3 Trial of NuSepin® in COVID-19 Pneumonia Patients</strong> - <b>Condition</b>: COVID-19 Pneumonia<br/><b>Interventions</b>: Drug: NuSepin® 0.2 mg/kg; Drug: NuSepin® 0.4 mg/kg; Drug: Placebo<br/><b>Sponsor</b>: Shaperon<br/><b>Recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Aerobic Exercise and Covid-19 Survivors With Post-Intensive Care Syndrome (Pics)</strong> - <b>Conditions</b>: COVID-19; Post Intensive Care Syndrome<br/><b>Interventions</b>: <br/>
|
||||
Other: Aerobic Exercise Training; Other: Home Plan<br/><b>Sponsor</b>: Riphah International University<br/><b>Not yet recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Efficacy and Safety of JT001 (VV116) Compared With Paxlovid</strong> - <b>Condition</b>: COVID-19<br/><b>Interventions</b>: Drug: JT001; Drug: Paxlovid<br/><b>Sponsor</b>: <br/>
|
||||
Vigonvita Life Sciences<br/><b>Recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles as Early Goal Directed Therapy for COVID-19 Moderate-to-Severe Acute Respiratory Distress Syndrome (ARDS): A Phase III Clinical Trial</strong> - <b>Condition</b>: COVID-19 Acute Respiratory Distress Syndrome<br/><b>Intervention</b>: Drug: EXOFLO<br/><b>Sponsor</b>: Direct Biologics, LLC<br/><b>Not yet recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Use of Continuous Glucose Monitors in Coronavirus Disease 2019 ICU and Potential Inpatient Settings</strong> - <b>Conditions</b>: Covid19; Diabetes Mellitus<br/><b>Intervention</b>: Device: continuous glucose monitoring<br/><b>Sponsor</b>: Tanureet K Arora<br/><b>Completed</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Phase Ⅱ Clinical Trial of SARS-CoV-2 mRNA Vaccine</strong> - <b>Condition</b>: SARS-CoV-2<br/><b>Interventions</b>: Biological: SARS-CoV-2 (LVRNA009) 50μg group; Biological: SARS-CoV-2 (LVRNA009) 100μg group; Other: Placebo<br/><b>Sponsors</b>: AIM Vaccine Co., Ltd.; Hunan Provincial Center for Disease Control and Prevention<br/><b>Active, not recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Sample Collection for Evaluation of the Panbio™ COVID-19/ Flu A&B Rapid Panel.</strong> - <b>Conditions</b>: COVID-19; Influenza A; Influenza Type B<br/><b>Intervention</b>: Diagnostic Test: Nasal and Nasopharyngeal Sampling of the Panbio™ COVID-19/ Flu A&B Rapid Panel<br/><b>Sponsor</b>: Abbott Rapid Dx<br/><b>Recruiting</b></p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Pilot Trial on Immunosuppression Modulation to Increase SARS-CoV-2 Vaccine Response in Kidney Transplant Recipients</strong> - <b>Condition</b>: COVID-19<br/><b>Interventions</b>: Other: Immunosuppression reduction; Other: No immunosuppression reduction<br/><b>Sponsor</b>: Medical University of Vienna<br/><b>Active, not recruiting</b></p></li>
|
||||
</ul>
|
||||
<h1 data-aos="fade-right" id="from-pubmed">From PubMed</h1>
|
||||
<ul>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Xuanfei Baidu decoction attenuates intestinal disorders by modulating NF-κB pathway, regulating T cell immunity and improving intestinal flora</strong> - CONCLUSIONS: Our data indicate that XFBD treatment attenuated intestinal disorders associated with inhibiting inflammation, remodeling of intestinal immunity, and improving intestinal flora. These findings provide a scientific basis for the clinical use of XFBD and offer a potential therapeutic approach for the treatment of COVID-19 patients with intestinal symptoms.</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Regulation of IFNα-induced expression of the short ACE2 isoform by ULK1</strong> - The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been shown to hijack angiotensin converting enzyme 2 (ACE2) for entry into mammalian cells. A short isoform of ACE2, termed deltaACE2 (dACE2), has recently been identified. In contrast to ACE2, the short dACE2 isoform lacks the ability to bind the spike protein of SARS-CoV-2. Several studies have proposed that expression of ACE2 and/or dACE2 is induced by interferons (IFNs). Here, we report that drug-targeted…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Promising therapeutic approach for SARS-CoV-2 infection by using a rutin-based combination therapy</strong> - The development of new therapeutic approaches for SARS-CoV-2 infection is of particular current importance. The combination therapy proposed here is based on already proven, safe compounds. The natural compound rutin, one of the six therapy components, has the potential to inhibit both viral and host cell targets. In addition, this therapy involves the use of acetylsalicylic acid, vitamin C and vitamin D 3 , which should be administered together with calcium and magnesium. The importance of each…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Phosphate-regulated expression of the SARS-CoV-2 receptor-binding domain in the diatom Phaeodactylum tricornutum for pandemic diagnostics</strong> - The worldwide COVID-19 pandemic caused by the SARS-CoV-2 betacoronavirus has highlighted the need for a synthetic biology approach to create reliable and scalable sources of viral antigen for uses in diagnostics, therapeutics and basic biomedical research. Here, we adapt plasmid-based systems in the eukaryotic microalgae Phaeodactylum tricornutum to develop an inducible overexpression system for SARS-CoV-2 proteins. Limiting phosphate and iron in growth media induced expression of the…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Inhibitory mechanism of Ambroxol and Bromhexine Hydrochlorides as potent blockers of molecular interaction between SARS-CoV-2 spike protein and human angiotensin-converting Enzyme-2</strong> - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects the host cells through interaction of its spike protein with human angiotensin-converting enzyme 2 (hACE-2). High binding affinity between the viral spike protein and host cells hACE-2 receptor has been reported to enhance the viral infection. Thus, the disruption of this molecular interaction will lead to reduction in viral infectivity. This study, therefore, aimed to analyze the inhibitory potentials of two mucolytic drugs;…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A raising dawn of pentoxifylline in management of inflammatory disorders in Covid-19</strong> - The existing pandemic viral infection caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) leads to coronavirus disease 2019 (Covid-19). SARS-CoV-2 exploits angiotensin-converting enzyme 2 (ACE2) as an entry-point into affected cells and down-regulation of ACE2 by this virus triggers the release of pro-inflammatory cytokines and up- regulation of angiotensin II. These changes may lead to hypercytokinemia and the development of cytokine storm with the development of acute…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The determination of haemagglutinin influenza antibodies in the Polish population in the epidemic season 2020/2021 during the SARS-CoV-2 pandemic</strong> - The aim of the study was to prove the level of antibodies against haemagglutinin in the sera of people from seven age groups in the epidemic season 2020/2021 in Poland to determine the differentiation of the antibody level and the protection rate depending on age. The level of anti-haemagglutinin antibodies was established by haemagglutinin inhibition test (HAI). A total of 700 randomly selected sera from people belonging to 7 different age groups were tested. The results confirmed the presence…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Harnessing Natural Products by a Pharmacophore-Oriented Semisynthesis Approach for the Discovery of Potential Anti- SARS-CoV-2 Agents</strong> - Natural products possessing unique scaffolds may have antiviral activity but their complex structures hinder facile synthesis. A pharmacophore-oriented semisynthesis approach was applied to (-)-maoelactone A ( 1 ) and oridonin ( 2 ) for the discovery of anti-SARS-CoV-2 agents. The Wolff rearrangement/lactonization cascade (WRLC) reaction was developed to construct the unprecedented maoelactone-type scaffold during semisynthesis of 1 . Further mechanistic study suggested a concerted mechanism for…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Inflammasome activation in infected macrophages drives COVID-19 pathology</strong> - Severe COVID-19 is characterized by persistent lung inflammation, inflammatory cytokine production, viral RNA, and sustained interferon (IFN) response all of which are recapitulated and required for pathology in the SARS-CoV-2 infected MISTRG6-hACE2 humanized mouse model of COVID-19 with a human immune system^(1-20). Blocking either viral replication with Remdesivir^(21-23) or the downstream IFN stimulated cascade with anti-IFNAR2 in vivo in the chronic stages of disease attenuated the…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Recent advances in passive immunotherapies for COVID-19: The Evidence-Based approaches and clinical trials</strong> - In late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged, causing a global pandemic called COVID-19. Currently, there is no definitive treatment for this emerging disease. Global efforts resulted in developing multiple platforms of COVID-19 vaccines, but their efficacy in humans should be wholly investigated in the long-term clinical and epidemiological follow-ups. Despite the international efforts, COVID-19 vaccination accompanies challenges, including financial and…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Mutations in the SARS-CoV-2 RNA dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms</strong> - The nucleoside analog remdesivir (RDV) is a Food and Drug Administration (FDA)-approved antiviral for treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. Thus, it is critical to understand factors that promote or prevent RDV resistance. We passaged SARS-CoV-2 in the presence of increasing concentrations of GS-441524, the parent nucleoside of RDV. After 13 passages, we isolated three viral lineages with phenotypic resistance as defined by increases in…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A multifunctional colorimetric sensor array for bacterial identification and real-time bacterial elimination to prevent bacterial contamination</strong> - Effective identification and real-time inactivation of pathogenic microorganisms is of great importance for preventing their infection and spread in public health, especially considering the huge threat of coronavirus disease 2019 (COVID-19). Herein, a novel multifunctional colorimetric sensor array with 3,3’,5,5’-tetramethylbenzidine (TMB) as a single probe has been constructed. TMB can be efficiently oxidized to generate oxidized TMB (oxTMB) by HAuCl(4), which displays four characteristic…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Hydrazones and Thiosemicarbazones Targeting Protein-Protein-Interactions of SARS-CoV-2 Papain-like Protease</strong> - The papain-like protease (PLpro) of SARS-CoV-2 is essential for viral propagation and, additionally, dysregulation of the host innate immune system. Using a library of 40 potential metal-chelating compounds we performed an X-ray crystallographic screening against PLpro. As outcome we identified six compounds binding to the target protein. Here we describe the interaction of one hydrazone (H1) and five thiosemicarbazone (T1-T5) compounds with the two distinct natural substrate binding sites of…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Versisterol, a new endophytic steroid with 3CL protease inhibitory activity from <em>Avicennia marina</em> (Forssk.) Vierh</strong> - A new epoxy ergostane sterol, named versisterol, was isolated from Aspergillus versicolor, an endophytic fungus from Avicennia marina. The structure of the isolated compound was deduced by means of one- and two-dimensional NMR and high- resolution mass spectrometry. The absolute stereochemistry was elucidated by NOESY analysis, and experimental and calculated time-dependent density functional theory (TD-DFT) circular dichroism spectroscopy. Versisterol inhibited 3CL protease (3CL^(pro)) with an…</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong><em>In silico</em> study of the inhibition of SARS-COV-2 viral cell entry by neem tree extracts</strong> - The outbreak of COVID-19, caused by SARS-COV-2, is responsible for higher mortality and morbidity rates across the globe. Until now, there is no specific treatment of the disease and hospitalized patients are treated according to the symptoms they develop. Efforts to identify drugs and/or vaccines are ongoing processes. Natural products have shown great promise in the treatment of many viral related diseases. In this work, using in silico methods, bioactive compounds from the neem tree were…</p></li>
|
||||
</ul>
|
||||
<h1 data-aos="fade-right" id="from-patent-search">From Patent Search</h1>
|
||||
|
||||
|
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<h1 data-aos="fade-down" id="daily-dose">Daily-Dose</h1>
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<h1 data-aos="fade-right" data-aos-anchor-placement="top-bottom" id="contents">Contents</h1>
|
||||
<ul>
|
||||
<li><a href="#from-new-yorker">From New Yorker</a></li>
|
||||
<li><a href="#from-vox">From Vox</a></li>
|
||||
<li><a href="#from-the-hindu-sports">From The Hindu: Sports</a></li>
|
||||
<li><a href="#from-the-hindu-national-news">From The Hindu: National News</a></li>
|
||||
<li><a href="#from-bbc-europe">From BBC: Europe</a></li>
|
||||
<li><a href="#from-ars-technica">From Ars Technica</a></li>
|
||||
<li><a href="#from-jokes-subreddit">From Jokes Subreddit</a></li>
|
||||
</ul>
|
||||
<h1 data-aos="fade-right" id="from-new-yorker">From New Yorker</h1>
|
||||
<ul>
|
||||
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The War in Ukraine Is a Colonial War</strong> - For centuries, the country has lived in the shadow of empire. But its past also provides the key to its present. - <a href="https://www.newyorker.com/news/essay/the-war-in-ukraine-is-a-colonial-war">link</a></p></li>
|
||||
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Can Liberty University Be Saved?</strong> - After Jerry Falwell, Jr.,’s ouster, some students and alumni have sought a more thorough excavation of Liberty’s values. - <a href="https://www.newyorker.com/news/annals-of-education/can-liberty-university-be-saved">link</a></p></li>
|
||||
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Worst Boyfriend on the Upper East Side</strong> - For decades, a man has romanced New York women, persuading them to invest in questionable business deals. How did he keep running the same scam? - <a href="https://www.newyorker.com/news/our-local-correspondents/the-worst-boyfriend-on-the-upper-east-side">link</a></p></li>
|
||||
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Kyiv After Dark</strong> - An artist captures the fight for airspace over the Ukrainian capital. - <a href="https://www.newyorker.com/news/news-desk/kyiv-after-dark">link</a></p></li>
|
||||
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Camille Bordas Reads Saul Bellow</strong> - The author joins Deborah Treisman to read and discuss “A Father-to-Be,” by Saul Bellow, which was published in a 1955 issue of the magazine. - <a href="https://www.newyorker.com/podcast/fiction/camille-bordas-reads-saul-bellow">link</a></p></li>
|
||||
</ul>
|
||||
<h1 data-aos="fade-right" id="from-vox">From Vox</h1>
|
||||
<ul>
|
||||
<li><strong>What happens when The Real World turns you into an “Angry Black Woman”</strong> -
|
||||
<figure>
|
||||
<img alt="" src="https://cdn.vox-
|
||||
cdn.com/thumbor/evOskDsts0JN1_CpNPdODPEFUsg=/17x0:777x570/1310x983/cdn.vox-
|
||||
cdn.com/uploads/chorus_image/image/70818523/melissa.0.png"/>
|
||||
<figcaption>
|
||||
Melissa Beck from The Real World Homecoming: New Orleans | Paramount+
|
||||
</figcaption>
|
||||
</figure>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
Real World: Homecoming is a second chance for the seminal series, and for New Orleans castmate Melissa Beck.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="0QZLI8">
|
||||
“I just want you to know that I don’t like you. We’re not friends, because I find you to be very dishonest,” <a href="https://www.instagram.com/melissabeckrwno/">Melissa Beck</a> (née Howard) said to Julie Stoffer the last time the two were on TV together on MTV’s<em> Battle of the Sexes</em> in 2003. “You got your smug little smile and think it’s all cute — you’re a backstabber and you’re a liar.”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ZscVKm">
|
||||
Then, in a separate confessional, Melissa uttered a phrase that’s become a part of MTV canon: “You go messing with my money, you go messing with my emotions.”
|
||||
</p></li>
|
||||
</ul>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Jt6FpP">
|
||||
Melissa and Julie had left their season of <em>The Real World: New Orleans</em> as best friends. Two years later, they were onscreen enemies, and Melissa was pigeonholed as “The Angry Black Woman.”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="sKEUov">
|
||||
<em>The Real World</em> will go down as one of the more progressive shows in television history for documenting the lives of gay people, people of color, and other underrepresented groups. But in its 33-season run, it could also lean on stereotypes — like the Angry Black Woman — to tell those stories. <em>Real World: Homecoming,</em> a new weekly Paramount+ series starring Melissa and the rest of her <em>New Orleans</em> housemates, is trying to right those wrongs and allow the cast to reassess their experiences.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="TVhXtR">
|
||||
“Listen, there were abs and there was comedy — it’s iconic,” <a href="https://melissabeck.merchdirect.com/categories/accessories">Melissa</a>, now a 44-year- old mom of three living on Long Island, told Vox in a recent interview. Reflecting on her fight with Julie, she said, “My arm is so thin. My stomach is so flat. I had a great tan. And I was cussing somebody out. I have no apologies about that.”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="HvVhKU">
|
||||
Being able to laugh at yourself is a gift, but getting to this point wasn’t easy for Melissa. Looking back, it’s clear how <em>The Real World</em> failed Melissa and other Black women: Kameelah Phillips, who was on the show’s Boston edition, Arissa Hill on <em>Las Vegas</em>, Coral Smith on <em>Back to</em> <em>New York</em>. All were portrayed as versions of <a href="https://www.ferris.edu/HTMLS/news/jimcrow/antiblack/sapphire.htm">the Angry Black Woman,</a> a stereotype rooted in the false and racist idea that anger is ingrained within a Black woman’s nature rather than a normal human response to a frustrating situation.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="zgPnby">
|
||||
It’s not that <em>The Real World</em> and other reality programs can’t show Black women and women of color having angry moments. The problem is how that anger is so often presented.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ap26u5">
|
||||
Going back on the show is an opportunity for Melissa to tell her story and make sure viewers know she was more than the Black woman who cussed out the white girl.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="UZ12VY">
|
||||
“I also figured,” she said, “what’s the worst that could happen?”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jxfoMY">
|
||||
</p>
|
||||
<hr class="p-entry-hr" id="iv4ipq"/>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="O9qXmz">
|
||||
<strong>In Melissa’s original season</strong>, she and her housemates took a swamp boat tour during which the white guide called one of the bird species by a name that included the n-word. Melissa was disturbed by the guide’s casual use of the word and upset with her castmate Jamie’s reaction. He made excuses for the guide, saying that he wasn’t purposely using the word in a hurtful way. Melissa tried in vain to explain that there is no way for white people to use that word and not have it be malicious.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="t8AOZd">
|
||||
She knew she had the right to be angry, but the editing questioned that and in turn emboldened fans. After the show aired, she was hounded by viewers. Social media didn’t exist at the time, but people sent their attacks by email.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="7tGn5t">
|
||||
“For months, I was called racist, that I’m race-obsessed, that I’m race-baiting,” she said. “Every racist thing that could be hurled toward me was, and I don’t think that as a cast — because we hadn’t kept in touch with each other over the years — they understood that perspective or the impact that had on my life.”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="0KKrjp">
|
||||
After the season aired, Melissa and some <a href="https://pagesix.com/2022/04/20/real-world-star-danny-roberts-on-julies-alleged-homophobic-
|
||||
letter/">former</a> <em>Real World</em> <a href="https://www.reddit.com/r/MtvChallenge/comments/7rl8ef/reality_bytes_coral_smith_podcast_havent_seen/">castmates</a> alleged that Julie stole their opportunities on the lucrative (at the time) college speaker circuit. They claimed Julie would offer to speak at the schools for a smaller fee than her castmates, and the colleges — looking to save money — would book Julie instead. Because <em>Battle of the Sexes</em> producers didn’t offer viewers this context, the Melissa/Julie fight appeared to come out of left field.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="PeaJsf">
|
||||
“It’s the first time viewers had seen Melissa and Julie from <em>The Real World</em>, who left the show frolicking through a bed of roses. They came back, and now Melissa is screaming her head off,” Melissa said. “Instead of it being like, ‘Melissa was genuinely hurt by a friend who went behind her back and fucked with her money,’ it was, ‘Wow, Melissa’s really petty, I can’t believe she voted her off — Melissa’s a terrible person.’”
|
||||
</p>
|
||||
<figure class="e-image">
|
||||
<img alt=" " src="https://cdn.vox-
|
||||
cdn.com/thumbor/t2cmP-KIlVHS2zVQVrWcURwFCbE=/800x0/filters:no_upscale()/cdn.vox-
|
||||
cdn.com/uploads/chorus_asset/file/23429705/realworlnew.jpeg"/> <cite>Paramount+</cite>
|
||||
<figcaption>
|
||||
Melissa Beck and Danny Roberts on The Real World Homecoming: New Orleans
|
||||
</figcaption>
|
||||
</figure>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="hnq3Zl">
|
||||
Because she was seen as inherently rage-filled — an Angry Black Woman — anything she criticized became easy to dismiss, whether it was a situation that’s plainly racist like the one on the boat or her business dispute with Julie.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="pjirdW">
|
||||
Critics and <a href="https://www.ferris.edu/HTMLS/news/jimcrow/antiblack/sapphire.htm">scholars</a> note that while the Angry Black Woman caricature has roots in minstrel shows of the early 1900s, the radio show <em>Amos ’n’ Andy</em> — which debuted in 1928 — is what led to its <a href="https://www.researchgate.net/publication/299859537_Sapphire_Exploring_The_Power_Of_A_Popular_Stereotype">popularization</a>. <em>Amos ’n’ Andy</em>, a show about Black characters that was created and voiced by two white men, features <a href="https://vawnet.org/events/unpacking-sapphire-stereotype-protect-black-girls">Sapphire</a>, an aggressive scold; “the Sapphire,” in fact, became shorthand for the Angry Black Woman caricature. The stereotype began to appear as an <a href="https://nmaahc.si.edu/explore/stories/popular-and-pervasive-stereotypes-african-americans">onscreen trope</a> as the film industry took hold in the <a href="https://www.ferris.edu/HTMLS/news/jimcrow/antiblack/sapphire.htm">1930s</a> and carried over into the television age (<em>Amos ’n’ Andy</em> itself became a TV show in 1951).
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="M1UjTd">
|
||||
Sustained, harmful pop culture portrayals like these generate <a href="https://scholars.org/contribution/how-racial-stereotypes-popular-media-affect-people-and-what-hollywood-can-do-
|
||||
become">real-world bias</a> with real-world effects. Studies have shown that the Angry Black Woman stereotype has led to Black women receiving <a href="https://pubmed.ncbi.nlm.nih.gov/33793257/">negative performance evaluations at work</a>, <a href="https://pubmed.ncbi.nlm.nih.gov/24188294/">less effective mental health treatment</a>, and <a href="https://pubmed.ncbi.nlm.nih.gov/31112918/">discrimination during maternity care</a>.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="WWjbeA">
|
||||
<em>The Real World</em> premiered in 1992, more than 60 years after the premiere of <em>Amos ’n’ Andy</em>. It was an era when tabloid talk shows like <em>The Jerry Springer Show</em>, <em>The Maury Povich Show</em>, and <em>The Jenny Jones Show </em>were wildly popular — and heavily reliant on the Angry Black Woman and <a href="https://slate.com/culture/2018/08/the-racial-dynamics-in-maury-make-my-stomach-churn.html">other</a> <a href="https://www.complex.com/music/2019/11/chuck-d-accuses-maury-povich-jerry-springer-exploiting-black-people">racist tropes</a>.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="rAkDU7">
|
||||
<em>The Real World </em>purported to be more thoughtful. It promised to show real-life young people dealing with real-life issues like sexuality, religion, and gender — and for some of its audience, the show was the first time they would get to “know” people that they might not encounter in their own lives.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xNP30C">
|
||||
It’s that last part that bothers some of the show’s Black female alums who spoke to Vox: In many ways, <em>The Real World</em> was progressive, educational, and <a href="https://www.theringer.com/tv/2020/4/29/21240341/the-
|
||||
real-world-cultural-influence-chappelles-show-parodies">highly influential</a>, but it still relied on tropes and dynamics that privileged white people’s point of view at the expense of others.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="1651266466.974129">
|
||||
First- season cast member Julie Gentry’s storyline was that she was a sheltered, small-town white girl from Alabama. In the final stretch of the season, Julie accused her Black roommate Kevin Powell of threatening her after she interrupted one of his personal phone calls. He refuted her telling of the story and explained to her and the other castmates that accusing a Black person of violence is a serious matter, citing the Rodney King trial (which coincided with the taping of the show). Julie called Kevin <a href="https://www.mtv.com/video-clips/erba2g/the-real-world-kevin-and-julie-argue-
|
||||
over-cultural-differences">racist, psychotic, and capable of violence</a> and said she didn’t want to be alone in the house with him. The roommates largely took her side.<strong> </strong>Julie and Kevin reconciled on their season of <a href="https://www.avclub.com/the-real-worlds-kevin-julie-and-andre-on-racism-and-t-1846411168"><em>Homecoming</em></a>, and Julie has talked in <a href="https://www.latimes.com/entertainment-arts/tv/story/2021-03-08/julie-oliver-gentry-the-
|
||||
real-world-new-york-reunion">interviews</a> about how her views on race have changed since her experience on the show.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="qqCpSQ">
|
||||
“If we look at the storytelling of the original <em>The Real World</em>,” Melissa said, “the viewpoint that has always been the most important perspective was the doe-eyed white girl that walks into the house.”
|
||||
</p>
|
||||
<hr class="p-entry-hr" id="ltStPn"/>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="FuDjRx">
|
||||
<strong>Three seasons prior to </strong><em><strong>New Orleans</strong></em>, on <em>The Real World: Boston</em>, Kameelah Phillips experienced something similar to Melissa. <a href="https://www.instagram.com/drkameelahsays/?hl=en">Kameelah</a>, 44, <a href="https://www.callawomenshealth.com/">is now an obstetrician</a> based in New York City.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="rQXHHH">
|
||||
On the show, Kameelah was 19, taking a break from Stanford. She clashed with Sean Duffy, then 25, who went on to serve as a Republican Congress member from 2011 through 2019. In one of their final fights on the show, Kameelah told him that she was exhausted from having to teach him about Blackness and Black culture. In response, Sean compared her to Hitler.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="zIxeLv">
|
||||
“I definitely think I got a bit of the Angry Black Woman stereotype,” Kameelah said.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="8DZzLG">
|
||||
She theorized that because she butted heads with a white man whose storyline was about how he was sheltered and conservative, she came off as mad and aggressive. She says she was also portrayed at times as the <a href="https://pdxscholar.library.pdx.edu/mcnairsymposium/2020/presentations/12/">“lonely” and “bitter” Black woman</a>, as the show implied that she was hostile to her fellow Black castmate Syrus Yarbrough because he dated white women.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XazFWh">
|
||||
“That was a storyline I felt was created to run that narrative of Black women being alone and or being just so grumpy that they can’t get along, when that wasn’t the case at all,” Kameelah said. Like Melissa, she received a stream of racist abuse when the show aired.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="W5VKry">
|
||||
“I remember checking DOS or some basic email and I had hate mail there. I was like,<em> ‘</em>Why? What is going on?’ I definitely experienced a negative backlash from strangers,” she said. “People called me horrible names, so I got to a point where I had very negative emotions about this show.”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="dqThkE">
|
||||
Arissa Hill, who was on <em>The Real World: Las Vegas</em>, hasn’t watched her run on the show, which aired in 2002. Still, she’s heard plenty about how fans believe her season ruined the franchise. While <a href="https://ew.com/recap/reunited-real-world-vegas-grown-pains/"><em>Las Vegas</em> was a ratings monster</a>,<em> </em>producers<em> </em>were criticized by <a href="https://stopbeingpolite.com/2018/12/18/game-changers-the-real-world-
|
||||
las-vegas/">viewers</a> and <a href="https://www.theringer.com/tv/2020/4/29/21240376/the-real-world-mtv-
|
||||
best-25-seasons">critics</a> for turning the show into something overly argumentative and overtly sexual rather than the more introspective seasons of prior <em>Real World</em>s.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4LtGHx">
|
||||
What strikes Arissa most about how her season was edited is that she and her roommates spent a lot of time having fun together and lovingly teasing each other. Most of that good-natured ribbing was left on the cutting room floor. “I believe we were fucking hilarious,” she said.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="A59C2F">
|
||||
That the cast’s lighter moments didn’t make the cut didn’t necessarily surprise her, since she quickly understood the narrative producers were attempting to create. The season that made it to air featured love triangles, a pregnancy scare, and plenty of shouting and scolding. Arissa was often at the center of the confrontations, frequently fighting with her white castmate Frank Roessler, whom MTV described as “wide-eyed” and someone who “makes friends easily.”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Qo4xKA">
|
||||
Their dynamic wasn’t unlike that of Kameelah and Sean, or Melissa and Julie. The Angry Black Woman and Wide-Eyed Young White Person are stereotypes that simultaneously shortchange both of the people they supposedly portray, but it’s inherently more damaging to be portrayed as angry — which is seen as a permanent character flaw — than being sheltered, which one will presumably grow out of.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="yLsVaU">
|
||||
“Do we have the Angry Black Woman or somebody who is just trying to assert themselves or assert a boundary that has been crossed?” Arissa asked.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xbh5Xa">
|
||||
Arissa is working on a docuseries that’s inspired by her experience after <em>The Real World</em> stopped filming. Like Melissa, Arissa didn’t know how to navigate her image post-show. Every single time her season re-aired during a marathon or in syndication, there was a new round of people who knew Arissa only as that person — the villain, the scold, the fight-starter — on <em>Las Vegas</em>.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ODsE2M">
|
||||
“I want the opportunity to reclaim my likeness and rebrand myself, and tell stories the way that I’d like to tell them,” she said. “I am not the only person that feels this way. There’s a space for a story like this, and it’s been a long time coming.”
|
||||
</p>
|
||||
<hr class="p-entry-hr" id="WaD5Wr"/>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="DIbPAT">
|
||||
<strong>After deciding to reenter </strong><em>The Real World </em>fold, Melissa stressed to producers that she was concerned that the emotional labor of explaining and teaching people about race was going to fall on her shoulders yet again. She was also worried that the show wouldn’t explore the other aspects of her life. “I wanted to be able to be a whole and full person outside of who I am as my race,” she said.
|
||||
</p>
|
||||
<figure class="e-image">
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><img alt=" " src="https://cdn.vox-
|
||||
cdn.com/thumbor/LWzrhauACrfXbGQLazmItTEsP1A=/800x0/filters:no_upscale()/cdn.vox-
|
||||
cdn.com/uploads/chorus_asset/file/23425983/RWNOLA_308_111721_EK_0329_R.jpeg"/> <cite>MTV Entertainment</cite></p>
|
||||
<figcaption>
|
||||
Melissa Beck from<em> The Real World: New Orleans.</em>
|
||||
</figcaption>
|
||||
</figure>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="OstQCU">
|
||||
<em>Homecoming</em> executive producer and showrunner James Knox said he fully understood Melissa’s worries. Knox didn’t work on the original season, and he has no qualms discussing how the 2000 series and<em> Battle of the Sexes</em> fell short. Knox, a queer Black man, noted that Julie was the main character, with Melissa and Danny (Danny came out on the show as gay) used as accessories to her story.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XZUSnJ">
|
||||
“That season was all through Julie’s perspective,” he said of <em>Real World: New Orleans.</em> “I needed to allow for Melissa and Danny to lead their own stories independent of Julie being naive.”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="O3Nme5">
|
||||
The centering of the white experience and the use of the Angry Black Woman trope was, and continues to be, a problem in reality television. Following <em>The Real World</em>, it was perpetuated in series from <em>Survivor</em> to <em>The Apprentice</em> to the various <em>Real Housewives</em> franchises. What’s changed over the last decade or so is that we’re less inclined to buy into them. Audiences, <a href="https://www.washingtonpost.com/arts-entertainment/interactive/2021/black-women-reality-tv/">reality show participants themselves</a>, and even the people who make reality television now, are all more aware and ready to call out these lazy portrayals.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="uckThi">
|
||||
“Back then, we didn’t have the language to describe what was going on. We didn’t have ‘diversity and inclusion.’ We didn’t use the word ‘equity.,” Kameelah said. “We’ve, in the past 20 years, developed the tools to call things out when we see injustices — not just on TV.”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="SPKzQM">
|
||||
Knox told Melissa that <em>Homecoming</em> wasn’t about any kind of redemption narrative for her; this also wouldn’t be a sympathy edit to make up for what happened in 2000. What he and his team wanted to do is tell the story of seven strangers picked to live in a house — and how their lives had changed once the cameras moved on.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="DAFBBN">
|
||||
Part of what convinced Melissa to sign on was the fact that, in addition to Knox, there were many people of color involved in making <em>Homecoming. </em>With a more diverse crew and an audience that’s fluent in topics of identity like race and class, Knox said, there’s now a way to tell fuller stories that — while not perfect — do not have the same blind spots as the show did before.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="bkqr9E">
|
||||
The first episode of <em>Homecoming </em>revisits the Melissa and Julie fight. This time around, Melissa was given space to talk about the situation and the hurt it caused. The episode also included a moment in which Melissa’s castmates discussed the damage that can be done when a white person calls a person of color a liar.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ib6lU4">
|
||||
“Melissa has had to have this conversation a lot, and that’s tiring — that’s a burden and it shouldn’t be her burden,” Melissa’s castmate Kelley Wolf told Vox. Kelley said that living with Melissa again, and reliving those moments, made Kelley more empathetic to Melissa and brought the two closer than when the show first aired.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="95a5kf">
|
||||
Melissa said that, in her first run on MTV, she didn’t have the language to easily express what she knew to be true about race, identity, and the way her castmates were treating her back in 2000.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="zhW3vn">
|
||||
“I was a messy, vulnerable 22-year-old girl from the South, who was awkward, biracial, with bad teeth, who had a lot of feelings, and who was coming into her own in terms of identity,” Melissa said. She has unapologetic affection for that version of herself, someone who approached the experiment earnestly, if naively. Melissa kept all that in mind as she filmed this reunion.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jQVdN7">
|
||||
“Did it hinder the process of me being able to be real? I don’t think so.”
|
||||
</p>
|
||||
<ul>
|
||||
<li><strong>Can Sri Lanka dig itself out of a $50 billion debt?</strong> -
|
||||
<figure>
|
||||
<img alt="SRI LANKA-ECONOMY-POLITICS-PROTEST" src="https://cdn.vox-
|
||||
cdn.com/thumbor/VMrEnfEqzAFGTPb4kwBjfME5Orw=/317x0:5384x3800/1310x983/cdn.vox-
|
||||
cdn.com/uploads/chorus_image/image/70816907/1240346996.0.jpg"/>
|
||||
<figcaption>
|
||||
Protesters take part in an anti- government demonstration near the president’s office in Colombo on April 30, 2022, demanding President Gotabaya Rajapaksas resignation over the country’s crippling economic crisis. | Ishara S. Kodikara for AFP via Getty Images
|
||||
</figcaption>
|
||||
</figure>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
A mountain of foreign debt has led the country to default on loans for the first time since their 1948 independence.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="lNqYJ3">
|
||||
After a month of intense civilian-led protests over Sri Lanka’s deteriorating economy, President Gotabaya Rajapaksa agreed to appoint a new council on Friday to lead the formation of an interim government. The resolution would create a coalition made up of all parties in Parliament and would remove the grip of the Rajapaksa family dynasty currently ruling the country. At issue is the country’s economic future which is in shambles after defaulting on payments on its mountain of foreign loans — estimated to be worth $50 billion — <a href="https://apnews.com/article/business-international-monetary-fund-sri-lanka-foreign-
|
||||
debt-f48b3cfb388c3a11af5d2d8a3d1a4391">for the first time</a> since the country gained independence from the British in 1948.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="AwUNv0">
|
||||
Signs of Sri Lanka’s impending economic crisis became increasingly apparent over the last two years of the Covid-19 pandemic as <a href="https://www.nytimes.com/2022/03/25/world/asia/sri-lanka-economic-
|
||||
crisis.html">food prices soared and power blackouts</a> increased in frequency. Sri Lanka currently has about $7 billion in total debt due this year.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="oPiftU">
|
||||
Many attribute Sri Lanka’s economic crisis to the mishandling of its finances by successive governments through mounting foreign debt and continued infrastructure investments. The Rajapaksa administration also implemented <a href="https://apnews.com/article/b6b96849ebe74c8dbeac461ff8418c28">sweeping tax cuts in 2019</a>, slashing the value added tax (VAT) rate — the tax applied to imports and domestic supplies — from 15 percent to eight percent which contributed to a decrease in the country’s revenue.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="r5AeRD">
|
||||
The president’s older brother, Mahinda Rajapaksa, is expected to be removed as prime minister as part of an agreement brokered by former President Maithripala Sirisena, who defected with dozens of other members of the incumbent president’s governing party in April in protest of the Rajapaksas’ poor governing.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="5vuOLd">
|
||||
But the country’s power struggle may have sown discord between the two brothers which could exacerbate its political impasse. On Friday, the Associated Press <a href="https://apnews.com/article/business-biden-cabinet-sri-lanka-maithripala-sirisena-
|
||||
bc8ed130537eb090b9bc648b1b470d76">reported</a> a spokesperson for the prime minister did not immediately confirm the elder Rajapaksa’s removal, saying that any such decisions would be announced by the prime minister in due time.
|
||||
</p>
|
||||
<h3 id="SXJypo">
|
||||
The country continued to mount foreign debt without sufficient revenue
|
||||
</h3>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4JSlaL">
|
||||
A big part of Sri Lanka’s economic woes is its ballooning foreign debt, namely to fund its aggressive turn to infrastructure development under former President Mahinda Rajapaksa, the elder Rajapaksa sibling and two-time prime minister. With its finances already bleeding, Sri Lanka took out major investment loans from state-owned Chinese banks to fund its infrastructure projects including a controversial port development in the Hambantota district.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Xd1AD7">
|
||||
The Sri Lankan government justified the Hambantota project as a way to grow its economy as a bustling trade hub comparable to Singapore. However, the project was riddled with corruption and stalled, and Sri Lanka eventually <a href="https://www.nytimes.com/2018/06/25/world/asia/china-sri-lanka-port.html">handed over the port’s control</a> to China as collateral after it was unable to pay back its loans.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="EfRhuy">
|
||||
Over the last decade, Sri Lanka amassed <a href="https://www.nytimes.com/2018/06/25/world/asia/china-sri-lanka-port.html">a debt of $5 billion to China</a> alone, making up a large portion of its overall foreign debt, according to the BBC. Sri Lanka’s bloated debt to China and the Hambantota project failure are often held up as an example of the “debtbook diplomacy” that China has pursued in the last couple of decades.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="RETbob">
|
||||
Some believe China has expanded that monetary diplomacy approach through its ambitious Belt and Road Initiative (BRI), a global infrastructure project involving Chinese investment in infrastructure developments in parts of Asia, Africa, and Europe that is later repaid, as part of China’s bid to increase global influence as a growing economic power. About 139 out of 146 of the world’s countries, including Sri Lanka, have signed on to China’s BRI project. While an infrastructure project on such a global scale may provide some economic benefits to the participating countries, the BRI has inevitably become a strategic way for China to gain political leverage with economically vulnerable countries across the Asia-Pacific region. At least 16 countries involved in the BRI project have been saddled with billions of dollars of debt which China then has leveraged, according to an <a href="https://www.theguardian.com/world/2018/may/15/warning-sounded-over-chinas-debtbook-diplomacy">independent analysis</a> by Harvard’s Kennedy School for the US State Department.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="5ijWy8">
|
||||
About <a href="https://www.cnbc.com/2022/04/01/india-tries-to-pry-sri-lanka-loose-from-chinas-embrace.html">22 percent of Sri Lanka’s debt</a> is owed to bilateral creditors — institutional investors from foreign governments — according to CNBC. Neighboring India has sought to grow its bilateral cooperation with Sri Lanka partly as an attempt to secure its influence in South Asia over China. India recently gave Sri Lanka a $1.5 billion credit line to tide over the country’s fuel crisis in addition to another $2.4 billion through a currency swap and loan deferment since January.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="KPd5aL">
|
||||
As the country amassed foreign debt, its tourism sector — previously <a href="https://www.voanews.com/a/sri-
|
||||
lanka-tourism-plummets-after-bombings/4904347.html">a $44 billion industry</a> and a primary revenue source for the island — took successive hits. In 2019, tourism suffered after <a href="https://www.cnn.com/interactive/2019/04/world/sri-lanka-attacks/">a series of church bombings</a> that killed nearly 300 people, including some foreign nationals.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XC8Biv">
|
||||
The next year, the Covid-19 pandemic halted tourism and other major sectors, spurring a global economic downturn. Although Sri Lanka saw some increase in its number of foreign visitors last year, the ongoing pandemic combined with Russia’s invasion of Ukraine — both nations <a href="https://www.aljazeera.com/news/2022/4/6/crisis-hit-sri-lanka-is-hosting-thousands-of-stranded-ukrainians">leading sources of tourism</a> for Sri Lanka before the conflict — continued to slow the industry’s recovery.
|
||||
</p>
|
||||
<h3 id="DjBh4o">
|
||||
A worsening crisis triggered mass protests
|
||||
</h3>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="W4vs3u">
|
||||
The country’s issues escalated in March when the Sri Lankan government <a href="https://www.france24.com/en/live-news/20220330-10-hour-power-cuts-in-sri-lanka-as-
|
||||
crisis-worsens">announced</a> a 13-hour daily power cut as a way to save energy amid the ongoing crisis. Without sufficient power, many were unable to do their jobs as the economic crisis continued, prompting mass unrest. Thousands of Sri Lankans took to the streets in the weeks following the power cut to protest the country’s growing crisis.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="rXdNi0">
|
||||
On April 1, President Rajapaksa declared an emergency as growing unrest<strong> </strong>saw protesters clash with police. The entire Sri Lankan government Cabinet <a href="https://www.npr.org/2022/04/04/1090753152/sri-
|
||||
lanka-offers-resignations-as-public-anger-grows-over-economic-crisis">resigned in protest</a> not long after the emergency law was implemented, causing Rajapaksa to revoke the law. Among those who resigned was Sports Minister Namal Rajapaksa, another member of the Rajapaksa family and the president’s nephew.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="cgk2gZ">
|
||||
With growing political unrest and no resolution in sight, Rajapaksa’s rivals began calls for a no-confidence vote against his administration.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="wvaDYa">
|
||||
“We are confident we have the numbers and we will bring the motion at the appropriate time,” opposition lawmaker Harsha de Silva <a href="https://www.cnbc.com/2022/04/18/sri-lankan-opposition-to-table-no-
|
||||
confidence-vote-against-government-.html">told</a> CNBC. Hoping to placate critics, President Rajapaksa sought to form a new unity coalition under his leadership but failed to gain support. In April, the government also announced it would temporarily suspend foreign debt payments, marking the first time Sri Lanka had defaulted on foreign loans since its independence.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="bNWTGc">
|
||||
Experts had been warning of a potential dire situation around the country’s finances for some time. When the country defaulted, the government had been <a href="https://www.bbc.com/news/business-61145854">negotiating a bailout plan</a> with the International Monetary Fund, which had assessed its accumulated debt as unsustainable.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="RpffQy">
|
||||
“The government intends to pursue its discussions with the IMF as expeditiously as possible with a view to formulating and presenting to the country’s creditors a comprehensive plan for restoring Sri Lanka’s external public debt to a fully sustainable position,” the Finance Ministry said in a <a href="https://apnews.com/article/business-international-monetary-fund-sri-lanka-foreign-
|
||||
debt-f48b3cfb388c3a11af5d2d8a3d1a4391">statement</a>.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="FVqMeG">
|
||||
In a meeting with Cabinet officials a week later, President Rajapaksa <a href="https://apnews.com/article/business-biden-cabinet-sri-lanka-mahinda-
|
||||
rajapaksa-c85718a88d4ff03d2a72f969eb595afa">acknowledged</a> his government’s role in the country’s declining economy. Specifically, the president said the government should have approached the IMF earlier for support in tackling its unruly foreign debt and that they should have avoided the ban on imported chemical fertilizers which was meant to preserve Sri Lanka’s foreign exchange holdings but instead hurt its agricultural production.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="BYRGeu">
|
||||
“During the last two and a half years we have had vast challenges. The Covid-19 pandemic, as well as the debt burden, and some mistakes on our part,” Rajapaksa said.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Ips2BN">
|
||||
Now, Sri Lanka’s future rests on whether the president’s proposed government changes will placate his growing opposition long enough for a solution to come through from the IMF. The Sri Lankan head of finance, Nandalal Weerasinghe, has stated that such a hoped-for deal could <a href="https://www.france24.com/en/live-news/20220429-crisis-hit-sri-lanka-says-imf-bailout-three-months-away">still be months away</a>, however.
|
||||
</p></li>
|
||||
<li><strong>The Great Resignation is becoming a “great midlife crisis”</strong> -
|
||||
<figure>
|
||||
<img alt="Graphic of professionals holding briefcases on a conveyor belt taking them toward a door marked
|
||||
“EXIT.”" src="https://cdn.vox-cdn.com/thumbor/_w7TTrwvPlMS-KRjsQauUGatG4w=/232x0:2119x1415/1310x983/cdn.vox-
|
||||
cdn.com/uploads/chorus_image/image/70814786/GettyImages_1350030499.0.jpg"/>
|
||||
<figcaption>
|
||||
The Great Resignation is not just for kids. | Getty Images/iStockphoto
|
||||
</figcaption>
|
||||
</figure>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
Older, more tenured people are increasingly quitting their jobs.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="DPwhFs">
|
||||
With prices soaring and <a href="https://www.cnn.com/2022/04/26/economy/inflation-recession-economy-deutsche-bank/index.html">analysts predicting</a> a recession on the horizon, it might not seem like the best time to quit your job. But that’s not keeping American workers, especially older, more tenured ones, from doing so.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="fWCnNN">
|
||||
Higher-paid workers are increasingly quitting their jobs, as the Great Resignation — also known as the Great Reshuffle — enters its second year. Earlier in the pandemic, the trend was led by younger, less-tenured workers in low-paying industries like retail, food service, and health care. Now, the main growth in quit rates is coming from older, more tenured workers in higher-paid industries like finance, tech, and other knowledge worker fields, according to data from two separate human resources and analytics companies. These workers say they are searching for less tangible benefits like meaning and flexibility.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Mp3HQ6">
|
||||
That changing composition of who is quitting paints an increasingly complicated picture of the state of work in America and suggests that while quit rates have decreased slightly from their highs last year, the phenomenon is not going away just yet.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Hk6tWf">
|
||||
“The Great Resignation is almost like a train, where it’s built all this momentum and it’s hard to slow down, but certain workers are getting off the train and new workers are coming on,” said Luke Pardue, an economist at <a href="https://gusto.com/">Gusto</a>, which provides payroll, benefits, and human resource management software to small- and medium-sized businesses.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="L83JrT">
|
||||
Rates of quits are always highest among younger workers — those who tend to be less invested in their jobs and whose lives are less stable. This was true during the early stages of the pandemic when these workers quit their jobs amid heightened demand to eke out better wages and conditions elsewhere (though those gains are <a href="https://www.vox.com/the-
|
||||
highlight/22977654/future-of-work-restaurants-retail-hospitality">unlikely to be permanent</a>). But those quit rates have been declining. Data from Gusto, which typically works with companies that have around 25 employees, shows that the average tenure of people who quit has grown in every age group and in nearly every industry. In other words, older people who’ve worked at a job longer are also quitting.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4wvcIc">
|
||||
A similar change is happening at bigger companies, according to data from people analytics provider <a href="https://www.visier.com/">Visier</a>.
|
||||
</p>
|
||||
<div id="KyTkc2">
|
||||
<div id="datawrapper-ceS03">
|
||||
|
||||
</div></div></li>
|
||||
</ul>
|
||||
|
||||
<div id="5pNSUv">
|
||||
<div id="datawrapper-yDfl6">
|
||||
|
||||
</div>
|
||||
</div>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="haRSCq">
|
||||
Between the first quarter of 2021 and 2022, the greatest growth in resignations was among people aged 40 to 60 and those with a tenure of more than 10 years, a Visier dataset from companies with over 1,000 employees shows. Older and more tenured people are especially likely to be quitting in knowledge worker industries like finance and tech.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="LexOkA">
|
||||
Their reasons are myriad.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="t7d9MD">
|
||||
“Don’t look for one thing that’s driving the Great Resignation,” Ian Cook, Visier’s vice president of people analytics, told Recode. “It’s actually made up from a combination of different patterns and will continue to change as the labor market changes and as the economic recovery changes.”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="tivJ17">
|
||||
Among the more financially stable set, quits are being driven by<strong> </strong>everything from a desire to continue working remotely to a greater search for meaning to simply having the means to do so.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="8VNXf4">
|
||||
Columbia Business School professor Adam Galinsky calls this iteration of the Great Resignation the “great midlife crisis.”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="muzwXh">
|
||||
“At the midpoint of life, we become aware of our own mortality, and it allows us to reflect on what really matters to us,” said Galinsky. The pandemic has amplified that effect. “A global pandemic obviously makes people reflect on their own mortality in terms of being afraid of dying themselves or having a loved one or family and colleagues pass away.”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="j1foWy">
|
||||
Importantly, the people who quit to hold out for the jobs they want or forgo work entirely are usually the ones with the financial means to do so.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="6lzEK4">
|
||||
Galinsky, who is currently on sabbatical in Hawaii, says he’s seen it among his peers and among other high-earning knowledge workers now working from his island getaway. He mentioned a Bloomberg employee who quit after the finance publication called workers back to the office and who now works on a pasta truck.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="SxIOwh">
|
||||
Such workers, either due to savings or a spouse’s income, have the freedom to look for other work, including <a href="https://www.vox.com/recode/22651953/americans-gig-independent-workers-benefits-vacation-health-care-
|
||||
inequality">gig work</a> or <a href="https://www.vox.com/recode/22884040/more-americans-starting-own-business-
|
||||
entrepreneur">starting their own business</a>. A Gusto survey of new businesses shows that they’ve shifted from e-commerce startups earlier in the pandemic to more professional services, like, say, an accountant starting her own firm rather than working for someone else.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="MtEXWM">
|
||||
Many of these workers, especially those who are older and more stable in their careers, now have the perspective to consider what they really want out of their lives and work.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="6EXZC1">
|
||||
After more than two years of successfully working from home, many knowledge workers are loath to come back to the office, and some are jumping ship if they feel they have to do so. That makes sense. Data from Slack’s <a href="https://futureforum.com/">ongoing survey</a> of 10,000 knowledge workers <a href="https://futureforum.com/wp-content/uploads/2022/04/Future-Forum-Pulse-Report-April-2022.pdf">just found</a> that with a third of them now back in the office five days a week, their work-related stress and anxiety has reached its highest level since the survey began in 2020.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ySHrmK">
|
||||
Growth in knowledge worker quits also might just simply be a case of people copying one another.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="chQGom">
|
||||
“Workers who have this experience, that switched a job, that became more flexible, talk about it and how they had a great experience, and that leads their neighbor or their friend to do the same,” Pardue said.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="1RkiKT">
|
||||
They’re also quitting because there are a lot of jobs out there for them. The number of business and professional services job openings is at a record high, according to Bureau of Labor Statistics data. According to job site Indeed, the number of high-paid job postings has not cooled as much as postings for low-paid jobs (postings for both remain above pre-pandemic levels).
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="KX7EOm">
|
||||
So while the future might look grim, the present looks just fine for these workers, who are confident in the current tight job market. As Galinsky put it, “People believe less in global warming on days it snows.”
|
||||
</p>
|
||||
<h1 data-aos="fade-right" id="from-the-hindu-sports">From The Hindu: Sports</h1>
|
||||
<ul>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Still I Rise claims Nilgiris 2000 Guineas</strong> -</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Premier League: Rampant Man City back on top after 4-0 victory at Leeds</strong> - Man City have kept a clean sheet in their last five away Premier League matches; their longest ever run of consecutive away league clean sheets</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>IPL 2022 | Rahul, Hooda half-centuries take Lucknow Super Giants to 195/3 vs Delhi Capitals</strong> - LSG are placed at the third spot, while DC are currently at the sixth place in the overall standing</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>It was really unfair, I could have played the final: Sindhu on controversial point penalty at BAC</strong> - P.V. Sindhu blew a game-and-half lead after referee handed her a point penalty for taking too much time to serve between points, eventually losing 21-13 19-21 16-21 against Japan’s Akane Yamaguchi</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>After great start, Nadal returns from injury at Madrid Open</strong> - Nadal could face a semifinal against top-ranked Novak Djokovic</p></li>
|
||||
</ul>
|
||||
<h1 data-aos="fade-right" id="from-the-hindu-national-news">From The Hindu: National News</h1>
|
||||
<ul>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>High Court sets aside MCI order on discharging 787 MBBS students</strong> - Their dreams will shatter since they were admitted in the academic year 2016-17, says judge</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>India-UAE trade pact comes into force</strong> - India is negotiating trade agreements at a very fast pace with complementary economies, including the UK, Canada and the EU.</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Arrest of George to please communal forces: Surendran</strong> -</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Ukraine crisis: India calls for cessation of hostilities, resolution via dialogue ahead of PM Modi’s Europe visit</strong> - On his first trip abroad this year, Prime Minister Narendra Modi will embark on a three-day visit to Germany, Denmark and France beginning Monday amid the ongoing crisis in Ukraine</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Face masks likely to be made compulsory in Maharashtra if COVID-19 cases rise</strong> - Maharashtra reported 155 new coronavirus cases, as against 148 on Friday</p></li>
|
||||
</ul>
|
||||
<h1 data-aos="fade-right" id="from-bbc-europe">From BBC: Europe</h1>
|
||||
<ul>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Mariupol civilians leave besieged Azovstal steelworks</strong> - Despite an order from Vladimir Putin to completely seal off the area, 20 civilians escape Azovstal.</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>How Ukraine’s ‘Ghost of Kyiv’ legendary pilot was born</strong> - The “Ghost of Kyiv” story about a heroic pilot downing many Russian planes turns out to be a legend.</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Ukraine war: Resistance to Russian rouble in Kherson</strong> - Russian forces say the currency will be used there from Sunday. But many residents have other ideas.</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Germany takes Italy to UN court over Nazi-era compensation claims</strong> - Germany wants to stop property it owns in Italy being seized to finance compensation for Nazi war crimes</p></li>
|
||||
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Asylum in Denmark: Is the country guilty of double standards?</strong> - As thousands of Ukrainians are welcomed, the government plans to reduce the number of non-European refugees.</p></li>
|
||||
</ul>
|
||||
<h1 data-aos="fade-right" id="from-ars-technica">From Ars Technica</h1>
|
||||
<ul>
|
||||
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Scientists blast out Earth’s location with the hope of reaching aliens</strong> - “These efforts are like building a big bonfire in the woods and hoping someone finds you.” - <a href="https://arstechnica.com/?p=1851383">link</a></p></li>
|
||||
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The weekend’s best deals: Beats, iPads, Samsung portable SSD, and more</strong> - Dealmaster also has deals on Apple’s MacBook, Withings ScanWatch, Fire TV and more. - <a href="https://arstechnica.com/?p=1851472">link</a></p></li>
|
||||
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Every little bit helps: How to pick the least eco-hostile laptop</strong> - Laptops are generally bad for the environment—but some are less bad than others. - <a href="https://arstechnica.com/?p=1851486">link</a></p></li>
|
||||
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Tasting Coca-Cola’s first “gamer” flavor—and the history of game-and-soda tie-ins</strong> - Our dive into gaming-soda history goes back to the dubious <em>Pepsi Invaders</em>. - <a href="https://arstechnica.com/?p=1850159">link</a></p></li>
|
||||
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Review: Oura Ring 3 and Whoop 4.0 are 2 ambitious wearables, but they’re tough sells</strong> - A focus on recovery is welcome, but not at the cost of easy activity tracking. - <a href="https://arstechnica.com/?p=1838201">link</a></p></li>
|
||||
</ul>
|
||||
<h1 data-aos="fade-right" id="from-jokes-subreddit">From Jokes Subreddit</h1>
|
||||
<ul>
|
||||
<li><strong>Me: The earth isn’t flat!</strong> - <!-- SC_OFF -->
|
||||
<div class="md">
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
fiat earther: correct
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
me: huh?
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
fiat earther: it’s the shape of an Italian car
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
me: what?
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
fiat earther: you read my name wrong didn’t you?
|
||||
</p>
|
||||
</div>
|
||||
<!-- SC_ON -->
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/venzann"> /u/venzann </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/ufs52c/me_the_earth_isnt_flat/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/ufs52c/me_the_earth_isnt_flat/">[comments]</a></span></p></li>
|
||||
<li><strong>A man walks into a full bar with a loaded gun. He shouts “Who here has been fucking my wife!?”</strong> - <!-- SC_OFF -->
|
||||
<div class="md">
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
Everyone in the bar is quiet for a bit, until the bartender says “Mate, you don’t have enough bullets.”
|
||||
</p>
|
||||
</div>
|
||||
<!-- SC_ON -->
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/MesserMooney"> /u/MesserMooney </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/uflaxi/a_man_walks_into_a_full_bar_with_a_loaded_gun_he/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/uflaxi/a_man_walks_into_a_full_bar_with_a_loaded_gun_he/">[comments]</a></span></p></li>
|
||||
<li><strong>How do you know if your Husband watches porn?</strong> - <!-- SC_OFF -->
|
||||
<div class="md">
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
Play the Pornhub intro loud. If he notices, he watches porn.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
If he doesn’t notice, he watches porn without the audio.
|
||||
</p>
|
||||
</div>
|
||||
<!-- SC_ON -->
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/batmans_apprentice"> /u/batmans_apprentice </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/ufvlej/how_do_you_know_if_your_husband_watches_porn/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/ufvlej/how_do_you_know_if_your_husband_watches_porn/">[comments]</a></span></p></li>
|
||||
<li><strong>Last night, I was invited for a night out with the girls</strong> - <!-- SC_OFF -->
|
||||
<div class="md">
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
The other night I was invited out for a night with the ‘girls.’ I told my husband that I would be home by midnight, ‘I promise!’ Well, the hours passed and the drinks went down way too easily.<br/> Around 3 a.m., a bit pissed, I headed for home. Just as I got in the door, the cuckoo clock in the hallway started up and cuckooed 3 times. Quickly, realizing my husband would probably wake up, I cuckooed another 9 times.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
I was really proud of myself for coming up with such a quick-witted solution, in order to escape a possible conflict with him. (Even when totally smashed… 3 cuckoos plus 9 cuckoos totals 12 cuckoos MIDNIGHT!)
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
The next morning my husband asked me what time I got in, I told him ‘MIDNIGHT’… he didn’t seem pissed off in the least.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
Whew, I got away with that one! Then he said ‘We need a new cuckoo clock.’
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
When I asked him why, he said, ‘Well, last night our clock cuckooed three times, then said ’oh shit.’ Cuckooed 4 more times, cleared its throat, cuckooed another three times, giggled, cuckooed twice more, and then tripped over the coffee table and farted
|
||||
</p>
|
||||
</div>
|
||||
<!-- SC_ON -->
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/ambivalentmediocrity"> /u/ambivalentmediocrity </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/uft5c1/last_night_i_was_invited_for_a_night_out_with_the/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/uft5c1/last_night_i_was_invited_for_a_night_out_with_the/">[comments]</a></span></p></li>
|
||||
<li><strong>Iraqi Player plays for Detroit Lions</strong> - <!-- SC_OFF -->
|
||||
<div class="md">
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
The Coach of the Detroit Lions had put together the perfect football team. But then his quarterback got blindsided and was out for the season with a knee injury. Then his backup went down with a concussion. He tried the trading route, free agents, but nobody any good was available.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
One evening while watching the news from Iraq, he saw a young Iraqi soldier with an amazing arm. The soldier rifled a grenade on a perfect arc into a 4th story window from 100 yards, bam!
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
He tossed another directly into a tight group of 12 enemy fighters 80 yards away, ka-bam! Then a humvee passed, going 60 kph, boom! Another perfect shot! Coach said to himself, “I got to have this guy. He’s got the best arm I’ve ever seen!” He tracks him down and convinces him to come to Detroit. The kid takes coaching perfectly, makes all the plays, and long story short, the Lions win the Super Bowl. The Iraqi is now the Conquering Hero in pro football, and a huge story. But when the broadcast team tries to interview him, all he wants is to phone his mom.
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
“Mother,” he yells over the phone, “We just won the Super Bowl!”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
“Don’t talk to me,” the woman says. “You abandoned us. You can’t be my son.” The young Iraqi begs, “Mom, you don’t understand! Our team won the biggest game here in the U.S. Thousands of fans are screaming for me. The U.S. President is going to call me!”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
“I don’t care,” his mother snaps. “Right now I can hear gunshots everywhere. Our block is like a ruin. Your brothers were beaten half to death last night, and your sister was nearly raped.”
|
||||
</p>
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||
Then she says, "I can never forgive you for making us move to Detroit.
|
||||
</p>
|
||||
</div>
|
||||
<!-- SC_ON -->
|
||||
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/Sir_Oligarch"> /u/Sir_Oligarch </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/ufb3zh/iraqi_player_plays_for_detroit_lions/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/ufb3zh/iraqi_player_plays_for_detroit_lions/">[comments]</a></span></p></li>
|
||||
</ul>
|
||||
|
||||
|
||||
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Reference in New Issue