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<title>Covid-19 Sentry</title><meta content="width=device-width, initial-scale=1.0" name="viewport"/><link href="styles/simple.css" rel="stylesheet"/><link href="../styles/simple.css" rel="stylesheet"/><link href="https://unpkg.com/aos@2.3.1/dist/aos.css" rel="stylesheet"/><script src="https://unpkg.com/aos@2.3.1/dist/aos.js"></script></head>
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<h1 data-aos="fade-down" id="covid-19-sentry">Covid-19 Sentry</h1>
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<h1 data-aos="fade-right" data-aos-anchor-placement="top-bottom" id="contents">Contents</h1>
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<li><a href="#from-preprints">From Preprints</a></li>
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<li><a href="#from-clinical-trials">From Clinical Trials</a></li>
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<li><a href="#from-pubmed">From PubMed</a></li>
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<li><a href="#from-patent-search">From Patent Search</a></li>
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<h1 data-aos="fade-right" id="from-preprints">From Preprints</h1>
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<li><strong>Niclosamide Inhalation Powder Made by Thin-Film Freezing: Pharmacokinetic and Toxicology Studies in Rats and Hamsters</strong> -
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In this work, we have developed and tested in vivo a dry powder form of niclosamide made by thin-film freezing (TFF) and administered it by inhalation to rats and hamsters. The niclosamide dry powder, suitable for inhalation, is being developed as a therapeutic agent against COVID-19 infection. Niclosamide, a poorly water-soluble drug, is an interesting drug candidate because it was approved over 60 years ago for use as an anthelmintic medication, but recent studies demonstrated its potential as a broad-spectrum antiviral with a specific pharmacological effect against SARS-CoV-2 infection. In the past, clinical trials for other indications were terminated prior to completion due to low and highly variable oral bioavailability. In order to quickly address the current pandemic, targeting niclosamide directly to the lungs is rational to address the COVID-19 main clinical complications. Thin-film freezing technology was used to develop a niclosamide inhalation powder composition that exhibited acceptable aerosol performance with a fine particle fraction (FPF) of 86.0% and a mass median aerodynamic diameter (MMAD) and geometric standard deviation (GSD) of 1.11 microns and 2.84, respectively. This formulation not only proved to be safe after an acute three-day, multi-dose pharmacokinetic study in rats as evidenced by histopathology analysis, but also was able to achieve lung concentrations above the required IC50 and IC90 levels for at least 24 h after a single administration in a Syrian hamster model. To conclude, we successfully developed a niclosamide dry powder inhalation formulation by thin-film freezing for further scale-up and clinical testing against the COVID-19 infection. This approach overcomes limitations of niclosamide of poor oral bioavailability by targeting the drug directly to the primary site of infection, the lungs.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.01.26.428293v1" target="_blank">Niclosamide Inhalation Powder Made by Thin-Film Freezing: Pharmacokinetic and Toxicology Studies in Rats and Hamsters</a>
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<li><strong>TREM2 is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid hormone receptor</strong> -
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Triggering receptor expressed on myeloid cells-2 (TREM2) is a cell surface receptor on macrophages and microglia that senses and responds to disease associated signals to regulate the phenotype of these innate immune cells. The TREM2 signaling pathway has been implicated in a variety of diseases ranging from neurodegeneration in the central nervous system to metabolic disease in the periphery. We report here that TREM2 is a thyroid hormone regulated gene and its expression in macrophages and microglia is stimulated by thyroid hormone. Both endogenous thyroid hormone and sobetirome, a synthetic thyroid hormone agonist drug, suppress pro-inflammatory cytokine production from myeloid cells including macrophages that have been treated with the SARS-CoV-2 spike protein which produces a strong, pro-inflammatory phenotype. Thyroid hormone agonism was also found to induce phagocytic behavior in microglia, a phenotype consistent with activation of the TREM2 pathway. The thyroid hormone antagonist NH-3 blocks the anti-inflammatory effects of thyroid hormone agonists and suppresses microglia phagocytosis. Finally, in a murine experimental autoimmune encephalomyelitis (EAE) multiple sclerosis model, treatment with Sob-AM2, a CNS-penetrating sobetirome prodrug, results in increased Trem2 expression in disease lesion resident myeloid cells which correlates with therapeutic benefit in the EAE clinical score and reduced damage to myelin. Our findings represent the first report of endocrine regulation of TREM2 and provide a unique opportunity to drug the TREM2 signaling pathway with orally active small molecule therapeutic agents.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.01.25.428149v1" target="_blank">TREM2 is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid hormone receptor</a>
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</div></li>
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<li><strong>A deep learning framework for real-time detection of novel pathogens during sequencing</strong> -
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Motivation: Novel pathogens evolve quickly and may emerge rapidly, causing dangerous outbreaks or even global pandemics. Next-generation sequencing is the state-of-the art in open-view pathogen detection, and one of the few methods available at the earliest stages of an epidemic, even when the biological threat is unknown. Analyzing the samples as the sequencer is running can greatly reduce the turnaround time, but existing tools rely on close matches to lists of known pathogens and perform poorly on novel species. Machine learning approaches can predict if single reads originate from more distant, unknown pathogens, but require relatively long input sequences and processed data from a finished sequencing run. Results: We present DeePaC-Live, a Python package for real-time pathogenic potential prediction directly from incomplete sequencing reads. We train deep neural networks to classify Illumina and Nanopore reads and integrate our models with HiLive2, a real-time Illumina mapper. DeePaC-Live outperforms alternatives based on machine learning and sequence alignment on simulated and real data, including SARS-CoV-2 sequencing runs. After just 50 Illumina cycles, we increase the true positive rate 80-fold compared to the live-mapping approach. The first 250bp of Nanopore reads, corresponding to 0.5s of sequencing time, are enough to yield predictions more accurate than mapping the finished long reads. Our approach could also be used for screening synthetic sequences against biosecurity threats. Availability: The code is available at: https://gitlab.com/dacs-hpi/deepac-live and https://gitlab.com/dacs-hpi/deepac. The package can be installed with Bioconda, Docker or pip.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.01.26.428301v1" target="_blank">A deep learning framework for real-time detection of novel pathogens during sequencing</a>
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<li><strong>How scientific reasoning correlates with health-related beliefs and behaviors during the COVID-19 pandemic?</strong> -
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We examined whether scientific reasoning is associated with health-related beliefs and behaviors over and above general analytic thinking ability in the general public (N = 783, aged 18–84). Health-related beliefs included: anti-vaccination attitudes, COVID-19 conspiracy beliefs, and generic health-related epistemically suspect beliefs. Scientific reasoning correlated with generic pseudoscientific and health-related conspiracy beliefs and COVID-19 conspiracy beliefs. Crucially, scientific reasoning was a stronger independent predictor of unfounded beliefs (including anti-vaccination attitudes) than general analytic thinking was; however, it had a more modest role in health-related behaviors.
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🖺 Full Text HTML: <a href="https://psyarxiv.com/tfy5q/" target="_blank">How scientific reasoning correlates with health-related beliefs and behaviors during the COVID-19 pandemic?</a>
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<li><strong>Mechanism of Viral Glycoprotein Targeting by Membrane-associated-RING-CH Proteins</strong> -
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An emerging class of cellular inhibitory proteins has been identified that targets viral glycoproteins. These include the membrane-associated RING-CH (MARCH) family of E3 ubiquitin ligases that, among other functions, downregulate cell-surface proteins involved in adaptive immunity. The RING-CH domain of MARCH proteins is thought to function by catalyzing the ubiquitination of the cytoplasmic tails (CTs) of target proteins, leading to their degradation. MARCH proteins have recently been reported to target retroviral envelope glycoproteins (Env) and vesicular stomatitis virus G glycoprotein (VSV-G). However, the mechanism of antiviral activity remains poorly defined. Here we show that MARCH8 antagonizes the full-length forms of HIV-1 Env, VSV-G, Ebola virus glycoprotein (EboV-GP), and the spike (S) protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) thereby impairing the infectivity of virions pseudotyped with these viral glycoproteins. This MARCH8-mediated targeting of viral glycoproteins requires the E3 ubiquitin ligase activity of the RING-CH domain. We observe that MARCH8 protein antagonism of VSV-G is CT-dependent. In contrast, MARCH8-mediated targeting of HIV-1 Env, EboV-GP and SARS-CoV-2 S protein by MARCH8 does not require the CT, suggesting a novel mechanism of MARCH-mediated antagonism of these viral glycoproteins. Confocal microscopy data demonstrate that MARCH8 traps the viral glycoproteins in an intracellular compartment. We observe that the endogenous expression of MARCH8 in several relevant human cell types is rapidly inducible by type I interferon. These results help to inform the mechanism by which MARCH proteins exert their antiviral activity and provide insights into the role of cellular inhibitory factors in antagonizing the biogenesis, trafficking, and virion incorporation of viral glycoproteins.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.01.25.428025v1" target="_blank">Mechanism of Viral Glycoprotein Targeting by Membrane-associated-RING-CH Proteins</a>
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<li><strong>Variability in codon usage in Coronaviruses is mainly driven by mutational bias and selective constraints on CpG dinucleotide</strong> -
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The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the third virus within the Orthocoronavirinae causing an emergent infectious disease in humans, the ongoing coronavirus disease 2019 pandemic (COVID-19). Due to the high zoonotic potential of these viruses, it is critical to unravel their evolutionary history of host species shift, adaptation and emergence. Only such knowledge can guide virus discovery, surveillance and research efforts to identify viruses posing a pandemic risk in humans. We present a comprehensive analysis of the composition and codon usage bias of the 82 Orthocoronavirinae members, infecting 47 different avian and mammalian hosts. Our results clearly establish that synonymous codon usage varies widely among viruses and is only weakly dependent on the type of host they infect. Instead, we identify mutational bias towards AT-enrichment and selection against CpG dinucleotides as the main factors responsible of the codon usage bias variation. Further insight on the mutational equilibrium within Orthocoronavirinae revealed that most coronavirus genomes are close to their neutral equilibrium, the exception is the three recently-infecting human coronaviruses, which lie further away from the mutational equilibrium than their endemic human coronavirus counterparts. Finally, our results suggest that while replicating in humans SARS-CoV-2 is slowly becoming AT-richer, likely until attaining a new mutational equilibrium.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.01.26.428296v1" target="_blank">Variability in codon usage in Coronaviruses is mainly driven by mutational bias and selective constraints on CpG dinucleotide</a>
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<li><strong>Computational Investigation of Increased Virulence and Pathogenesis of SARS-CoV-2 Lineage B.1.1.7</strong> -
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New variants of SARS-CoV-2 are being reported worldwide. More specifically, the variants reported in South Africa (501Y.V2) and United Kingdom (B.1.1.7) were found to be more contagious than the wild type. There are also speculations that the variants might evade the host immune responses induced by currently available vaccines and develop resistance to drugs under consideration. The first step of viral infection in COVID-19, occurs through the interaction of receptor binding domain (RBD) of the spike protein with peptidase domain of the human ACE-2 (hACE-2) receptor. So, possibly the mutations in the RBD domain of spike protein in the new variants could modulate the protein-protein interaction with hACE-2 receptor leading to the increased virulence. In this study, we aim to get molecular level understanding into the mechanism behind the increased infection rate due to such mutations in these variants. We have computationally studied the interaction of the spike protein in both wild-type and B.1.1.7 variant with hACE-2 receptor using combined molecular dynamics and binding free energy calculations using molecular mechanics-Generalized Born surface area (MM-GBSA) approach. The binding free energies computed using configurations from minimization run and low temperature simulation show that mutant variant of spike protein has increased binding affinity for hACE-2 receptor (i.e. {triangleup}{triangleup}G(N501Y,A570D) is in the range -20.4 to -21.4 kcal/mol)The residue-wise decomposition analysis and intermolecular hydrogen bond analysis evidenced that the N501Y mutation has increased interaction between RBD of spike protein with ACE-2 receptor. We have also carried out calculations using density functional theory and the results evidenced the increased interaction between three pairs of residues (TYR449 (spike)-ASP38 (ACE-2), TYR453-HIE34 and TYR501-LYS353) in the variant that could be attributed to its increased virulence. The free energies of wild-type and mutant variants of the spike protein computed from MM-GBSA approach suggests that latter variant is stable by about -10.4 kcal/mol when compared to wild type suggesting that it will be retained in the evolution due to increased stability. We demonstrate that with the use of the state-of-the art of computational approaches, we can in advance predict the more virulent nature of variants of SARS-CoV-2 and alert the world health-care system.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.01.25.428190v1" target="_blank">Computational Investigation of Increased Virulence and Pathogenesis of SARS-CoV-2 Lineage B.1.1.7</a>
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<li><strong>40 minutes RT-qPCR Assay for Screening Spike N501Y and HV69-70del Mutations</strong> -
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A one-step reverse transcription and real-time PCR (RT-qPCR) test was developed for rapid screening (40 minutes) of the Spike N501Y and HV69-70del mutations in SARS-CoV-2 positive samples. The test also targets a conserved region of SARS-CoV-2 Orf1ab as an internal control. The samples containing both the N501Y and HV69-70del mutations are concluded as VOC-202012/01 positive. Samples suspected to be positive for B.1.351 or P.1 are the N501Y positive and HV69-70del negative cases. Limit of detection (LOD) of the kit for Orf1ab target is 500 copies/mL, while that of the N501, Y501 and HV69-70del targets are 5000 copies/mL. The developed assay was applied to 165 clinical samples containing SARS-CoV-2 from 32 different lineages. The SARS-CoV-2 lineages were determined via the next-generation sequencing (NGS). The RT-qPCR results were in 100% agreement with the NGS results that 19 samples were N501Y and HV69-70del positive, 10 samples were N501Y positive and HV69-70del negative, 1 sample was N501Y negative and HV69-70del positive, and 135 samples were N501Y and HV69-70del negative. All the VOC-202012/01 positive samples were detected in people who have traveled from England to Turkey. The RT-qPCR test and the Sanger sequencing was further applied to 1000 SARS-CoV-2 positive clinical samples collected in Jan2021 from the 81 different provinces of Turkey. The RT-qPCR results were in 100% agreement with the Sanger sequencing results that 32 samples were N501Y positive and HV69-70del negative, 4 samples were N501Y negative and HV69-70del positive, 964 samples were N501Y and HV69-70del negative. The specificity of the 40 minutes RT-qPCR assay relative to the sequencing-based technologies is 100%. The developed assay is an advantageous tool for timely and representative estimation of prevalence of the N501Y positive variants because it allows testing a much higher portion of the SARS-CoV-2 positives in much lower time compared to the sequencing-based technologies.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.01.26.428302v1" target="_blank">40 minutes RT-qPCR Assay for Screening Spike N501Y and HV69-70del Mutations</a>
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<li><strong>Kinetics and correlates of the neutralizing antibody response to SARS-CoV-2</strong> -
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A detailed understanding of antibody-based SARS-CoV-2 immunity has critical implications for overcoming the COVID-19 pandemic and for informing on vaccination strategies. In this study, we evaluated the dynamics of the SARS-CoV-2 antibody response in a cohort of 963 recovered individuals over a period of 10 months. Investigating a total of 2,146 samples, we detected an initial SARS-CoV-2 antibody response in 94.4% of individuals, with 82% and 79% exhibiting serum and IgG neutralization, respectively. Approximately 3% of recovered patients demonstrated exceptional SARS-CoV-2 neutralizing activity, defining them as elite neutralizers. These individuals also possessed effective cross-neutralizing IgG antibodies to SARS-CoV-1 without any known prior exposure to this virus. By applying multivariate statistical modeling, we found that sero-reactivity, age, time since disease onset, and fever are key factors predicting SARS-CoV-2 neutralizing activity in mild courses of COVID-19. Investigating longevity of the antibody response, we detected loss of anti-spike reactivity in 13% of individuals 10 months after infection. Moreover, neutralizing activity had an initial half-life of 6.7 weeks in serum versus 30.8 weeks in purified IgG samples indicating the presence of a more stable and long-term memory IgG B cell repertoire in the majority of individuals recovered from COVID-19. Our results demonstrate a broad spectrum of the initial SARS-CoV-2 neutralizing antibody response depending on clinical characteristics, with antibodies being maintained in the majority of individuals for the first 10 months after mild course of COVID-19.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.01.26.428207v1" target="_blank">Kinetics and correlates of the neutralizing antibody response to SARS-CoV-2</a>
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<li><strong>A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques</strong> -
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The deployment of a vaccine that limits transmission and disease likely will be required to end the Coronavirus Disease 2019 (COVID-19) pandemic. We recently described the protective activity of an intranasally-administered chimpanzee adenovirus-vectored vaccine encoding a pre-fusion stabilized spike (S) protein (ChAd-SARS-CoV-2-S) in the upper and lower respiratory tract of mice expressing the human angiotensin-converting enzyme 2 (ACE2) receptor. Here, we show the immunogenicity and protective efficacy of this vaccine in non-human primates. Rhesus macaques were immunized with ChAd-Control or ChAd-SARS-CoV-2-S and challenged one month later by combined intranasal and intrabronchial routes with SARS-CoV-2. A single intranasal dose of ChAd-SARS-CoV-2-S induced neutralizing antibodies and T cell responses and limited or prevented infection in the upper and lower respiratory tract after SARS-CoV-2 challenge. As this single intranasal dose vaccine confers protection against SARS-CoV-2 in non-human primates, it is a promising candidate for limiting SARS-CoV-2 infection and transmission in humans.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.01.26.428251v1" target="_blank">A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques</a>
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<li><strong>Increased Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 to Antibody Neutralization</strong> -
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The Covid-19 pandemic has ravaged the globe, and its causative agent, SARS-CoV-2, continues to rage. Prospects of ending this pandemic rest on the development of effective interventions. Two monoclonal antibody (mAb) therapeutics have received emergency use authorization, and more are in the pipeline. Furthermore, multiple vaccine constructs have shown promise, including two with ~95% protective efficacy against Covid-19. However, these interventions were directed toward the initial SARS-CoV-2 that emerged in 2019. Considerable viral evolution has occurred since, including variants with a D614G mutation that have become dominant. Viruses with this mutation alone do not appear to be antigenically distinct, however. Recent emergence of new SARS-CoV-2 variants B.1.1.7 in the UK and B.1.351 in South Africa is of concern because of their purported ease of transmission and extensive mutations in the spike protein. We now report that B.1.1.7 is refractory to neutralization by most mAbs to the N-terminal domain (NTD) of spike and relatively resistant to a number of mAbs to the receptor-binding domain (RBD). It is modestly more resistant to convalescent plasma (~3 fold) and vaccinee sera (~2 fold). Findings on B.1.351 are more worrisome in that this variant is not only refractory to neutralization by most NTD mAbs but also by multiple potent mAbs to the receptor-binding motif on RBD, largely due to an E484K mutation. Moreover, B.1.351 is markedly more resistant to neutralization by convalescent plasma (~11-33 fold) and vaccinee sera (~6.5-8.6 fold). B.1.351 and emergent variants with similar spike mutations present new challenges for mAb therapy and threaten the protective efficacy of current vaccines.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.01.25.428137v1" target="_blank">Increased Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 to Antibody Neutralization</a>
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<li><strong>A novel SARS-CoV-2 related coronavirus in bats from Cambodia</strong> -
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Knowledge of the origin and reservoir of the coronavirus responsible for the ongoing COVID-19 pandemic is still fragmentary. To date, the closest relatives to SARS-CoV-2 have been detected in Rhinolophus bats sampled in the Yunnan province, China. Here we describe the identification of SARS-CoV-2 related coronaviruses in two Rhinolophus shameli bats sampled in Cambodia in 2010. Metagenomic sequencing identified nearly identical viruses sharing 92.6% nucleotide identity with SARS-CoV-2. Most genomic regions are closely related to SARS-CoV-2, with the exception of a small region corresponding to the spike N terminal domain. The discovery of these viruses in a bat species not found in China indicates that SARS-CoV-2 related viruses have a much wider geographic distribution than previously understood, and suggests that Southeast Asia represents a key area to consider in the ongoing search for the origins of SARS-CoV-2, and in future surveillance for coronaviruses.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.01.26.428212v1" target="_blank">A novel SARS-CoV-2 related coronavirus in bats from Cambodia</a>
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<li><strong>Immunogenic Potential of DNA Vaccine candidate, ZyCoV-D against SARS-CoV-2 in Animal Models</strong> -
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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), initially originated in China in year 2019 and spread rapidly across the globe within 5 months, causing over 96 million cases of infection and over 2 million deaths. Huge efforts were undertaken to bring the COVID-19 vaccines in clinical development, so that it can be made available at the earliest, if found to be efficacious in the trials. We developed a candidate vaccine ZyCoV-D comprising of a DNA plasmid vector carrying the gene encoding the spike protein (S) of the SARS-CoV-2 virus. The S protein of the virus includes the receptor binding domain (RBD), responsible for binding to the human angiotensin converting enzyme (ACE-2) receptor. The DNA plasmid construct was transformed into E. coli cells for large scale production. The immunogenicity potential of the plasmid DNA has been evaluated in mice, guinea pig, and rabbit models by intradermal route at 25, 100 and 500g dose. Based on the animal studies proof-of-concept has been established and preclinical toxicology (PCT) studies were conducted in rat and rabbit model. Preliminary animal study demonstrates that the candidate DNA vaccine induces antibody response including neutralizing antibodies against SARS-CoV-2 and also provided Th-1 response as evidenced by elevated IFN-{gamma} levels.
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🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.01.26.428240v1" target="_blank">Immunogenic Potential of DNA Vaccine candidate, ZyCoV-D against SARS-CoV-2 in Animal Models</a>
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<li><strong>Elevated HScore is Associated with Poor Clinical Outcomes in COVID-19, Even in the Absence of Secondary Hemophagocytic Lymphohistiocytosis.</strong> -
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Introduction: Patients with Coronavirus Disease 2019 (COVID-19) frequently experience a hyperinflammatory syndrome, that leads to unfavorable outcomes. This condition resembles Secondary Hemophagocytic Lymphohistiocytosis (sHLH) described in neoplastic, rheumatic and other infectious diseases. However, it has not been prospectively studied on these patients. A scoring system (HScore) has been validated for sHLH, and recently proposed to evaluate hyperinflammation in COVID-19. Methods: 143 patients aged ≥18 years admitted because of COVID-19 were enrolled in a prospective, single-center, cohort study. HScore was calculated within the 72 hours since admission. The incidence of sHLH during hospitalization was evaluated. Additionally, the relationship between HScore ≥130 points and either the requirement of mechanical ventilation or 60-days mortality was explored. Results: The median age of enrolled patients was 57 (21-100), and 63.6% were male. The median HScore was 96 (33-169). One patient was diagnosed with sHLH (incidence 0,7%), due to a HScore of 169. After adjusting for age, sex, comorbidities and obesity, HScore ≥130 was independently associated with the composite clinical outcome (HR 2.13, p=0.022). Conclusion: sHLH is not frequent among COVID-19 patients. HScore can efficiently predict the risk for poor outcomes.
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🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.01.26.21249335v1" target="_blank">Elevated HScore is Associated with Poor Clinical Outcomes in COVID-19, Even in the Absence of Secondary Hemophagocytic Lymphohistiocytosis.</a>
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<li><strong>Colder and drier winter conditions are associated with greater SARS-CoV-2 transmission: a regional study of the first epidemic wave in north-west hemisphere countries.</strong> -
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Higher transmissibility of SARS-CoV-2 in cold and dry weather conditions has been hypothesized since the onset of the COVID-19 pandemic but the level of epidemiological evidence remains low. During the first wave of the pandemic for Spain, Italy, France, Portugal, Canada and USA presented an early spread, a heavy COVID-19 burden, and low initial public health response until lockdowns. We used regional death counts as a proxy for infections while diagnostic tests remained limited and calculated a basic reproduction number (R0) in 63 regions. After adjusting for population density, early spread of the epidemic, and aged population, temperature and humidity were negatively associated to SARS-CoV-2 transmissibility. A -1g/m3 lower mean absolute humidity was associated with a 0.15-unit higher R0. Below 10°C, a 1°C-higher temperature was associated with a 0.16-unit lower R0. Our results confirm a strong dependency of SARS-CoV-2 transmissibility to weather conditions in the absence of control measures. The initiation of the second wave in north-west hemisphere countries was likely triggered by the transition from summer- to winter-like conditions. High levels of restrictions to social activities should be maintained until spring to avoid or limit a third wave.
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🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.01.26.21250475v1" target="_blank">Colder and drier winter conditions are associated with greater SARS-CoV-2 transmission: a regional study of the first epidemic wave in north-west hemisphere countries.</a>
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<h1 data-aos="fade-right" id="from-clinical-trials">From Clinical Trials</h1>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Dexamethasone for COVID-19</strong> - <b>Condition</b>: Covid19<br/><b>Intervention</b>: Drug: Dexamethasone<br/><b>Sponsor</b>: University of Oklahoma<br/><b>Not yet recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Phase III Study of AZD7442 for Treatment of COVID-19 in Outpatient Adults</strong> - <b>Condition</b>: COVID-19<br/><b>Interventions</b>: Drug: AZD7442; Drug: Placebo<br/><b>Sponsor</b>: AstraZeneca<br/><b>Not yet recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Fluvoxamine Administration in Moderate SARS-CoV-2 (COVID-19) Infected Patients</strong> - <b>Condition</b>: Covid19<br/><b>Interventions</b>: Drug: Placebo; Drug: Fluvoxamine<br/><b>Sponsor</b>: SigmaDrugs Research Ltd.<br/><b>Recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The (HD)IVACOV Trial (The High-Dose IVermectin Against COVID-19 Trial)</strong> - <b>Condition</b>: Covid19<br/><b>Interventions</b>: Drug: Ivermectin 0.6mg/kg/day; Drug: Ivermectin 1.0mg/kg/day; Drug: Placebo; Drug: Hydroxychloroquine<br/><b>Sponsor</b>: Corpometria Institute<br/><b>Not yet recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>APT™ T3X on the COVID-19 Contamination Rate</strong> - <b>Condition</b>: COVID-19<br/><b>Interventions</b>: Drug: Tetracycline hydrochloride 3%; Drug: Placebo<br/><b>Sponsors</b>: University of Nove de Julho; Santa Casa de Misericórdia de Porto Alegre<br/><b>Not yet recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Study of ORTD-1 in Patients Hospitalized With COVID-19 Related Pneumonia</strong> - <b>Condition</b>: COVID-19<br/><b>Interventions</b>: Drug: ORTD-1 low dose; Drug: ORTD-1 mid dose; Drug: ORTD-1 high dose; Other: Vehicle control<br/><b>Sponsor</b>: Oryn Therapeutics, LLC<br/><b>Recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Efficacy of Nano-Ivermectin Impregnated Masks in Prevention of Covid-19 Among Healthy Contacts and Medical Staff</strong> - <b>Condition</b>: Covid-19<br/><b>Intervention</b>: Other: ivermectin impregnated mask<br/><b>Sponsor</b>: South Valley University<br/><b>Recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>COVID-19 Immunologic Antiviral Therapy With Omalizumab</strong> - <b>Condition</b>: Covid19<br/><b>Interventions</b>: Biological: Omalizumab; Other: Placebo<br/><b>Sponsor</b>: McGill University Health Centre/Research Institute of the McGill University Health Centre<br/><b>Not yet recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>IMUNOR® Preparation in the Prevention of COVID-19</strong> - <b>Condition</b>: Covid19<br/><b>Intervention</b>: Drug: IMUNOR<br/><b>Sponsor</b>: University Hospital Ostrava<br/><b>Not yet recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Clinical Experimentation With Tenofovir Disoproxyl Fumarate and Emtricitabine for COVID-19</strong> - <b>Condition</b>: Covid19<br/><b>Interventions</b>: Drug: Vitamin C 500 MG Oral Tablet; Drug: Tenofovir disoproxyl fumarate 300 MG Oral Tablet; Drug: Tenofovir disoproxyl fumarate 300 MG plus emtricitabine 200 MG Oral Tablet<br/><b>Sponsors</b>: Universidade Federal do Ceara; Conselho Nacional de Desenvolvimento Científico e Tecnológico; São José Hospital for Infectious Diseases - HSJ; Central Laboratory of Public Health of Ceará - Lacen-CE<br/><b>Recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Safety and Efficacy of Doxycycline and Rivaroxaban in COVID-19</strong> - <b>Condition</b>: COVID-19<br/><b>Interventions</b>: Drug: Doxycycline Tablets; Drug: Rivaroxaban 15Mg Tab; Combination Product: Hydroxychloroquine and Azithromycin<br/><b>Sponsor</b>: Yaounde Central Hospital<br/><b>Recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Phase IIb Clinical Trial of Recombinant Novel Coronavirus Pneumonia (COVID-19) Vaccine (Sf9 Cells)</strong> - <b>Condition</b>: COVID-19<br/><b>Interventions</b>: Biological: Recombinant COVID-19 vaccine (Sf9 cells); Biological: Placebo<br/><b>Sponsors</b>: Jiangsu Province Centers for Disease Control and Prevention; West China Hospital<br/><b>Not yet recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Famotidine vs Placebo for the Treatment of Non-Hospitalized Adults With COVID-19</strong> - <b>Condition</b>: Covid-19<br/><b>Interventions</b>: Drug: Famotidine; Drug: Placebo<br/><b>Sponsors</b>: Northwell Health; Cold Spring Harbor Laboratory<br/><b>Recruiting</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Antiseptic Mouth Rinses to Reduce Salivary Viral Load in COVID-19 Patients</strong> - <b>Condition</b>: Covid19<br/><b>Interventions</b>: Drug: Betadine© bucal 100 mg/ml; Drug: Oximen® 3%; Drug: Clorhexidine Dental PHB©; Drug: Vitis Xtra Forte©; Drug: Distilled Water<br/><b>Sponsors</b>: Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana; Hospital Universitario Fundación Jiménez Díaz; Hospital Universitario General de Villalba; Hospital Universitario Infanta Elena; Hospital Universitario Virgen de la Arrixaca; Hospital Clínico Universitario de Valencia; Dentaid SL<br/><b>Completed</b></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>COVID-19 and Pregnancy: Placental and Immunological Impacts</strong> - <b>Condition</b>: Covid19<br/><b>Intervention</b>: Other: Specimens specific for the study<br/><b>Sponsor</b>: Hopital Foch<br/><b>Recruiting</b></p></li>
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</ul>
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<h1 data-aos="fade-right" id="from-pubmed">From PubMed</h1>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein</strong> - Most human monoclonal antibodies (mAbs) neutralizing SARS-CoV-2 recognize the spike (S) protein receptor-binding domain and block virus interactions with the cellular receptor angiotensin-converting enzyme 2. We describe a panel of human mAbs binding to diverse epitopes on the N-terminal domain (NTD) of S protein from SARS-CoV-2 convalescent donors and found a minority of these possessed neutralizing activity. Two mAbs (COV2-2676 and COV2-2489) inhibited infection of authentic SARS-CoV-2 and...</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>BRD2 inhibition blocks SARS-CoV-2 infection in vitro by reducing transcription of the host cell receptor ACE2</strong> - SARS-CoV-2 infection of human cells is initiated by the binding of the viral Spike protein to its cell-surface receptor ACE2. We conducted an unbiased CRISPRi screen to uncover druggable pathways controlling Spike protein binding to human cells. We found that the protein BRD2 is an essential node in the cellular response to SARS-CoV-2 infection. BRD2 is required for ACE2 transcription in human lung epithelial cells and cardiomyocytes, and BRD2 inhibitors currently evaluated in clinical trials...</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant</strong> - Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of deaths worldwide and massive societal and economic burden. Recently, a new variant of SARS-CoV-2, known as B.1.1.7, was first detected in the United Kingdom and is spreading in several other countries, heightening public health concern and raising questions as to the resulting effectiveness of vaccines and therapeutic interventions. We and others previously...</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A PCR amplicon-based SARS-CoV-2 replicon for antiviral evaluation</strong> - The development of specific antiviral compounds to SARS-CoV-2 is an urgent task. One of the obstacles for the antiviral development is the requirement of biocontainment because infectious SARS-CoV-2 must be handled in a biosafety level-3 laboratory. Replicon, a non-infectious self-replicative viral RNA, could be a safe and effective tool for antiviral evaluation. Herein, we generated a PCR-based SARS-CoV-2 replicon. Eight fragments covering the entire SARS-CoV-2 genome except S, E, and M genes...</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Molecular Docking of Azithromycin, Ritonavir, Lopinavir, Oseltamivir, Ivermectin and Heparin Interacting with Coronavirus Disease 2019 Main and Severe Acute Respiratory Syndrome Coronavirus-2 3C-Like Proteases</strong> - In the current pandemic situation raised due to COVID-19, drug reuse is emerging as the first line of treatment. The viral agent that causes this highly contagious disease and the acute respiratory syndrome coronavirus (SARS-CoV) share high nucleotide similarity. Therefore, it is structurally expected that many existing viral targets are similar to the first SARS-CoV, probably being inhibited by the same compounds. Here, we selected two viral proteins based on their vital role in the viral life...</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Development of a Cell-Based Luciferase Complementation Assay for Identification of SARS-CoV-2 3CL(pro) Inhibitors</strong> - The 3C-like protease (3CL^(pro)) of SARS-CoV-2 is considered an excellent target for COVID-19 antiviral drug development because it is essential for viral replication and has a cleavage specificity distinct from human proteases. However, drug development for 3CL^(pro) has been hindered by a lack of cell-based reporter assays that can be performed in a BSL-2 setting. Current efforts to identify 3CL^(pro) inhibitors largely rely upon in vitro screening, which fails to account for cell permeability...</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Protective Effects of Lactoferrin against SARS-CoV-2 Infection In Vitro</strong> - SARS-CoV-2 is a newly emerging virus that currently lacks curative treatments. Lactoferrin (LF) is a naturally occurring non-toxic glycoprotein with broad-spectrum antiviral, immunomodulatory and anti-inflammatory effects. In this study, we assessed the potential of LF in the prevention of SARS-CoV-2 infection in vitro. Antiviral immune response gene expression was analyzed by qRT-PCR in uninfected Caco-2 intestinal epithelial cells treated with LF. An infection assay for SARS-CoV-2 was...</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Repositioning of histamine H(1) receptor antagonist: Doxepin inhibits viropexis of SARS-CoV-2 Spike pseudovirus by blocking ACE2</strong> - The spread of the corona virus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been intensifying in the past year, posing a huge threat to global health. There is an urgent need for effective drugs and vaccines to fight the COVID-19, but their advent may not be quite fast. Drug repurposing is a feasible strategy in the current situation, which could greatly shorten drug development time and help to response quickly to the novel virus...</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: A pilot, double-blind, placebo-controlled, randomized clinical trial</strong> - BACKGROUND: Ivermectin inhibits the replication of SARS-CoV-2 in vitro at concentrations not readily achievable with currently approved doses. There is limited evidence to support its clinical use in COVID-19 patients. We conducted a Pilot, randomized, double-blind, placebo-controlled trial to evaluate the efficacy of a single dose of ivermectin reduce the transmission of SARS-CoV-2 when administered early after disease onset.</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Pragmatic, open-label, single-center, randomized, phase II clinical trial to evaluate the efficacy and safety of methylprednisolone pulses and tacrolimus in patients with severe pneumonia secondary to COVID-19: The TACROVID trial protocol</strong> - INTRODUCTION: Some COVID-19 patients evolve to severe lung injury and systemic hyperinflammatory syndrome triggered by both the coronavirus infection and the subsequent host-immune response. Accordingly, the use of immunomodulatory agents has been suggested but still remains controversial. Our working hypothesis is that methylprednisolone pulses and tacrolimus may be an effective and safety drug combination for treating severe COVID-19 patients.</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Polyphenols as promising biologically active substances for preventing SARS-CoV-2: A review with research evidence and underlying mechanisms</strong> - Currently, antiviral drugs and/or vaccines are not yet available to treat or prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this review, we narrated the available data, from credible publishers, regarding the possible role of polyphenols and natural extracts-containing polyphenols in the prevention of coronavirus disease 2019 (COVID-19), and their immune-boosting properties. It was revealed that polyphenols could be considered as promising biologically active substances...</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Luteolin and abyssinone II as potential inhibitors of SARS-CoV-2: an in silico molecular modeling approach in battling the COVID-19 outbreak</strong> - CONCLUSIONS: Conclusively, the current study proposes that luteolin and abyssinone II might act as potential therapeutic candidates for SARS-CoV-2 infection. In vivo and in vitro experiments, however, should be taken under consideration to determine the efficiency and to demonstrate the mechanism of action.</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Identifying anti-coronavirus peptides by incorporating different negative datasets and imbalanced learning strategies</strong> - As the current worldwide outbreaks of the SARS-CoV-2, it is urgently needed to develop effective therapeutic agents for inhibiting the pathogens or treating the related diseases. Antimicrobial peptides (AMP) with functional activity against coronavirus could be a considerable solution, yet there is no research for identifying anti-coronavirus (anti-CoV) peptides with the computational approach. In this study, we first investigated the physiochemical and compositional properties of the collected...</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients: An observational cohort study</strong> - Antibody responses are important in the control of viral respiratory infection in the human host. What is not clear for SARS-CoV-2 is how rapidly this response occurs, or when antibodies with protective capability evolve. Hence, defining the events of SARS-CoV-2 seroconversion and the time frame for the development of antibodies with protective potential may help to explain the different clinical presentations of COVID-19. Furthermore, accurate descriptions of seroconversion are needed to inform...</p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Targeting cyclooxygenase enzyme for the adjuvant COVID-19 therapy</strong> - Despite vigorous efforts, the COVID-19 pandemic continues to take a toll on the global health. The contemporary therapeutic regime focused on the viral spike proteins, viral 3CL protease enzyme, immunomodulation, inhibition of viral replication, and providing a symptomatic relief encouraged the repurposing of drugs to meet the urgency of treatment. Similarly, the representative drugs that proved beneficial to alleviate SARS-CoV-1, MERS-CoV, HIV, ZIKV, H1N1, and malarial infection in the past...</p></li>
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</ul>
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<h1 data-aos="fade-right" id="from-patent-search">From Patent Search</h1>
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>COVID-19 CLASSIFICATION RECOGNITION METHOD BASED ON CT IMAGES OF LUNGS</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU314054415">link</a></p></li>
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A traditional Chinese medicine composition for COVID-19 and/or influenza and preparation method thereof</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU313300659">link</a></p></li>
|
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Covid 19 - Chewing Gum</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU313269181">link</a></p></li>
|
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>STOCHASTIC MODEL METHOD TO DETERMINE THE PROBABILITY OF TRANSMISSION OF NOVEL COVID-19</strong> - The present invention is directed to a stochastic model method to assess the risk of spreading the disease and determine the probability of transmission of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=IN313339294">link</a></p></li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Fahrzeuglüftungssystem und Verfahren zum Betreiben eines solchen Fahrzeuglüftungssystems</strong> -
|
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
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</p><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">Die Erfindung betrifft ein Fahrzeuglüftungssystem (1) zum Belüften einer Fahrgastzelle (2) eines Fahrzeugs (3), mit einem Umluftpfad (5). Die Erfindung ist gekennzeichnet durch eine wenigstens abschnittsweise in einen Umluftansaugbereich (4) des Umluftpads (5) hineinreichende Sterilisationseinrichtung (6), wobei die Sterilisationseinrichtung (6) dazu eingerichtet ist von einem aus der Fahrgastzelle (2) entnommenen Luftstrom getragene Schadstoffe zu inaktivieren und/oder abzutöten.</p></li>
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=DE313868337">link</a></p></li>
|
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The use of human serum albumin (HSA) and Cannabigerol (CBG) as active ingredients in a composition for use in the treatment of Coronavirus (Covid-19) and its symptoms</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU313251184">link</a></p></li>
|
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The use of human serum albumin (HSA) and Cannabigerol (CBG) as active ingredients in a composition for use in the treatment of Coronavirus (Covid-19) and its symptoms</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU313251182">link</a></p></li>
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>"AYURVEDIC PROPRIETARY MEDICINE FOR TREATMENT OF SEVERWE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-COV-2."</strong> - AbstractAyurvedic Proprietary Medicine for treatment of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)In one of the aspect of the present invention it is provided that Polyherbal combinations called Coufex (syrup) is prepared as Ayurvedic Proprietary Medicine , Aqueous Extracts Mixing with Sugar Syrup form the following herbal aqueous extract coriandrum sativum was used for the formulation of protek.Further another Polyherbal combination protek as syrup is prepared by the combining an aqueous extract of the medicinal herbs including Emblica officinalis, Terminalia chebula, Terminalia belerica, Aegle marmelos, Zingiber officinale, Ocimum sanctum, Adatoda zeylanica, Piper lingum, Andrographis panivulata, Coriandrum sativum, Tinospora cordiofolia, cuminum cyminum,piper nigrum was used for the formulation of Coufex. - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=IN312324209">link</a></p></li>
|
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</p><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">Mund-Nasen-Bedeckung (1), wobei die Mund-Nasen-Bedeckung (1) mindestens an einem Ohr eines Trägers magnetisch befestigbar ist.</p></li>
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=DE313866760">link</a></p></li>
|
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Haptens, hapten conjugates, compositions thereof and method for their preparation and use</strong> - A method for performing a multiplexed diagnostic assay, such as for two or more different targets in a sample, is described. One embodiment comprised contacting the sample with two or more specific binding moieties that bind specifically to two or more different targets. The two or more specific binding moieties are conjugated to different haptens, and at least one of the haptens is an oxazole, a pyrazole, a thiazole, a nitroaryl compound other than dinitrophenyl, a benzofurazan, a triterpene, a urea, a thiourea, a rotenoid, a coumarin, a cyclolignan, a heterobiaryl, an azo aryl, or a benzodiazepine. The sample is contacted with two or more different anti-hapten antibodies that can be detected separately. The two or more different anti-hapten antibodies may be conjugated to different detectable labels. - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU311608060">link</a></p></li>
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<h1 data-aos="fade-down" id="daily-dose">Daily-Dose</h1>
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<h1 data-aos="fade-right" data-aos-anchor-placement="top-bottom" id="contents">Contents</h1>
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<ul>
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<li><a href="#from-new-yorker">From New Yorker</a></li>
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<li><a href="#from-vox">From Vox</a></li>
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<li><a href="#from-the-hindu-sports">From The Hindu: Sports</a></li>
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<li><a href="#from-the-hindu-national-news">From The Hindu: National News</a></li>
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<li><a href="#from-bbc-europe">From BBC: Europe</a></li>
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<li><a href="#from-ars-technica">From Ars Technica</a></li>
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<li><a href="#from-jokes-subreddit">From Jokes Subreddit</a></li>
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</ul>
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<h1 data-aos="fade-right" id="from-new-yorker">From New Yorker</h1>
|
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<ul>
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|
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Andrew Yang’s Ideas on Universal Basic Income Earned Him Fans. But Can He Win Votes?</strong> - His pitch in the mayoral race is for New York to become the “anti-poverty” city. - <a href="https://www.newyorker.com/news/our-local-correspondents/andrew-yangs-ideas-on-universal-basic-income-earned-him-fans-but-can-he-win-votes">link</a></p></li>
|
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Can the COVID-19 Vaccine Beat the Proliferation of New Virus Mutations?</strong> - Stopping transmission blocks the opportunity for viral mutation. Vaccination is the only means we have of standing in the virus’s way. - <a href="https://www.newyorker.com/news/daily-comment/can-the-covid-19-vaccine-beat-the-proliferation-of-new-virus-mutations">link</a></p></li>
|
||||||
|
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Navalny’s Long-Running Battle with Putin Enters a New Phase</strong> - The jailed opposition leader is creating a model of guerrilla political warfare for the digital age. - <a href="https://www.newyorker.com/news/dispatch/navalnys-long-running-battle-with-putin-enters-a-new-phase">link</a></p></li>
|
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|
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Biden’s Pandemic Plan Might Just Work</strong> - The coronavirus is devastating America, and getting worse—but it’s not too late for a concerted effort to save countless lives. - <a href="https://www.newyorker.com/science/medical-dispatch/joe-bidens-pandemic-plan-might-actually-work">link</a></p></li>
|
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|
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Bold Proposal to Ease Child Poverty Is the Essence of Bidenomics</strong> - By targeting Americans that have been hit hardest by the pandemic, and also addressing lasting inequities, the new Administration is approaching this moment as one of great potential as well as great peril. - <a href="https://www.newyorker.com/news/our-columnists/a-bold-proposal-to-ease-child-poverty-is-the-essence-of-bidenomics">link</a></p></li>
|
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|
</ul>
|
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|
<h1 data-aos="fade-right" id="from-vox">From Vox</h1>
|
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<ul>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Welcome to the “New” Issue of The Highlight</strong> -
|
||||||
|
<figure>
|
||||||
|
<img alt="An illustration of flowers growing over buildings, with the word “new” in balloon letters in the sky above them." src="https://cdn.vox-cdn.com/thumbor/LDSDO3_9sjhBKnpANjNMqbVf-p8=/188x0:1313x844/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/68726754/jan_issue_cover_still.0.jpg"/>
|
||||||
|
<figcaption>
|
||||||
|
Shreya Gupta for Vox
|
||||||
|
</figcaption>
|
||||||
|
</figure></li>
|
||||||
|
</ul>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
As a new year and a new administration begin, we explore life in transition, from the new utopias to parents bucking the “baby bust” to Congress’s newcomers.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ArXRP1">
|
||||||
|
If one can summon any optimism nearly a year into a grim and persistent pandemic, this is the moment to do it.
|
||||||
|
</p>
|
||||||
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="2OxcM2">
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||||||
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It is a new year, after all (<a href="https://www.vox.com/the-highlight/22201977/2020-doomsday-apocalypse-astrologers-memes-investigation">good riddance, 2020!</a>). Nearly 20 million Americans have rolled up their sleeves and <a href="https://www.nytimes.com/interactive/2020/us/covid-19-vaccine-doses.html">received a dose of a Covid-19 vaccine</a>. And no matter your political affiliation, a new administration and transformed Congress and Cabinet perennially serve as a kind of reset button for America, each unfamiliar face a reminder of how wide open the possibilities are. So we cross our fingers in unison and hope for the best.
|
||||||
|
</p>
|
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="TnFi69">
|
||||||
|
It only made sense that the latest issue of The Highlight look at life in this tenuous transition. From the beautiful and remote communities — the new utopias — where corona-cationers flock to avoid restrictions (and high numbers of Covid-19 cases), to the would-be parents bucking the pandemic “baby bust” trend and getting pregnant anyway, to first-term lawmakers’ inauspicious introduction to Capitol Hill, we confront a world in flux. With so much change afoot, we turned to poets, too, for words of inspiration and provocation at a time when people need a little bit of both. And if that doesn’t move you, perhaps a crystal to bring on positive thinking will.
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="CuSAw6"/>
|
||||||
|
<figure class="e-image">
|
||||||
|
<pre><code> <img alt="Art depicting a human silhouette surrounded by colors and waves." src="https://cdn.vox-cdn.com/thumbor/cps2VM9qa3anZdU5S_wHh5RVnuU=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/22244108/Vox_PoemsForANewYear_Lede_Final.jpg" />
|
||||||
|
<cite>Sarah Gonzales for Vox</cite></code></pre>
|
||||||
|
</figure>
|
||||||
|
<h3 id="3Br2Yn">
|
||||||
|
<a href="https://www.vox.com/the-highlight/22225378/poetry-poems-saeed-jones-richard-blanco-jane-hirshfield">Poems for a new year</a>
|
||||||
|
</h3>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="dlGsQy">
|
||||||
|
7 poets — including Saeed Jones, Alex Dimitrov, and Patty Crane — meditate on the year we’ve had, the one ahead, and our dark, persistent past.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="rcWpd9">
|
||||||
|
By Vox Staff
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="728wgI"/>
|
||||||
|
<figure class="e-image">
|
||||||
|
<pre><code> <img alt="Rep. Mondaire Jones speaks outdoors surrounded by signs that read, “The people have spoken.”" src="https://cdn.vox-cdn.com/thumbor/P6i4nPx12RCUEB2_UTghVlTaxSs=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/22246300/GettyImages_1229685695.jpg" />
|
||||||
|
<cite>Caroline Brehman/CQ-Roll Call Inc. via Getty Images</cite>
|
||||||
|
<figcaption>Rep. Mondaire Jones.</figcaption></code></pre>
|
||||||
|
</figure>
|
||||||
|
<h3 id="CNPza3">
|
||||||
|
<a href="https://www.vox.com/the-highlight/22233575/congress-freshman-insurrection-capitol-riot-mondaire-jones">Class of 2021: Mondaire Jones on his “jarring” start as a first-term lawmaker</a>
|
||||||
|
</h3>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="oPhKZR">
|
||||||
|
The New York Democrat discusses the growing progressive movement in his party, and how the US Capitol riot is shaping his priorities.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="eeIvBP">
|
||||||
|
By Li Zhou
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="xeNANT"/>
|
||||||
|
<figure class="e-image">
|
||||||
|
<pre><code> <img alt=" " src="https://cdn.vox-cdn.com/thumbor/47XS9nV2CajbO3okgkO-xX4f71I=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/22260993/GettyImages_1253641601.jpg" />
|
||||||
|
<cite>Getty Images/iStockphoto</cite></code></pre>
|
||||||
|
</figure>
|
||||||
|
<h3 id="PdYYLp">
|
||||||
|
The new utopia
|
||||||
|
</h3>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4lmw52">
|
||||||
|
<em>Coming Thursday</em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Y6QxDt">
|
||||||
|
For a certain jet-setting sect, wide-open spaces with views, few Covid-19 cases, and the freedom to go maskless are all the rage. But who pays the price?
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Xp64oL">
|
||||||
|
By Sarah Khan
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="iOCMp2"/>
|
||||||
|
<figure class="e-image">
|
||||||
|
<pre><code> <img alt=" " src="https://cdn.vox-cdn.com/thumbor/LxyiG_lZBV1wiIwKDyROXRPXNLA=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/22221608/GettyImages_820874922.jpg" />
|
||||||
|
<cite>Getty Images</cite></code></pre>
|
||||||
|
</figure>
|
||||||
|
<h3 id="SMXx8C">
|
||||||
|
New crystal, new you?
|
||||||
|
</h3>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="iAcNSE">
|
||||||
|
<em>Coming Friday</em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="lJ58FW">
|
||||||
|
As crystals’ soothing popularity continues, one — carnelian — attracts those in search of self-improvement and positivity. Is it too good to be true?
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="sLWhw0">
|
||||||
|
By Jaya Saxena
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="i4UP5q"/>
|
||||||
|
<figure class="e-image">
|
||||||
|
<pre><code> <img alt=" " src="https://cdn.vox-cdn.com/thumbor/_8ifZJR0rc2DQZxv-zLK29imcYw=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/22260992/GettyImages_78392851.jpg" />
|
||||||
|
<cite>Getty Images</cite></code></pre>
|
||||||
|
</figure>
|
||||||
|
<h3 id="XznPlf">
|
||||||
|
What “baby bust”? New and soon-to-be parents on choosing to have kids in dark times.
|
||||||
|
</h3>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="mxWwDv">
|
||||||
|
<em>Coming Monday</em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="a0aMVB">
|
||||||
|
“Maybe it’s like a psychological trick to make yourself feel better, but I don’t regret it.”
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="r3IKKj">
|
||||||
|
By Chris Chafin
|
||||||
|
</p>
|
||||||
|
<ul>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Poems for a new year</strong> -
|
||||||
|
<figure>
|
||||||
|
<img alt="Art depicting a human silhouette surrounded by colors and waves." src="https://cdn.vox-cdn.com/thumbor/pGqUXPEm-2GZtH4bUi3_85z97hc=/360x0:4111x2813/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/68696929/Vox_PoemsForANewYear_Lede_Final.0.jpg"/>
|
||||||
|
<figcaption>
|
||||||
|
Illustrations by Sarah Gonzales for Vox
|
||||||
|
</figcaption>
|
||||||
|
</figure></li>
|
||||||
|
</ul>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
7 poets — including Saeed Jones, Alex Dimitrov, and Patty Crane — meditate on the year we’ve had, the one ahead, and our dark, persistent past.
|
||||||
|
</p>
|
||||||
|
<div class="c-float-left">
|
||||||
|
<figure class="e-image">
|
||||||
|
<pre><code> <img alt=" " src="https://cdn.vox-cdn.com/thumbor/YYgW4HsU995yniG4Y5QuEoQvF0Y=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/21899595/VOX_The_Highlight_Box_Logo_Horizontal.png" /></code></pre>
|
||||||
|
</figure>
|
||||||
|
</div>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="bSeTLe">
|
||||||
|
Part of <a href="https://www.vox.com/e/22014742"><strong>The “New” Issue</strong></a> of <a href="https://www.vox.com/the-highlight"><strong>The Highlight</strong></a>, our home for ambitious stories that explain our world.
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="PPKvPS"/>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="kPiYxy">
|
||||||
|
Good poetry can help us hold two opposing ideas in our minds at once.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="2xdOhD">
|
||||||
|
For instance: A new year is a blank page, waiting for us to write on it. It is a chance to begin all over again. A new presidential administration offers us the same chance. After the year we’ve had, we have to believe in the possibility of a fresh beginning.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="wyrM9q">
|
||||||
|
But also, how can you turn the page on 2020, much less on four years of tumult under Donald Trump? How can you imagine that what was written won’t keep bleeding out into 2021?
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="fIqIeJ">
|
||||||
|
Last year’s police brutality protests turned into this year’s off-duty cops rioting at the Capitol; last year’s hopes for a quick vaccine to quell the<strong> </strong>pandemic turned into this year’s 4,000 people dead in one<strong> </strong>day. And no matter what happens under a new administration, our losses will stay lost. There are no fresh starts, and there are no blank pages, and we have to believe that, too.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="5DoLT5">
|
||||||
|
To try to pull apart this moment, we turned to poets from across the country and asked them to send us poems for a new year. The poets represent the country, including 2014 finalist for the National Book Critics Circle Award for poetry Saeed Jones; 2020 US youth poet laureate Meera Dasgupta; former inaugural poet Richard Blanco; and former Academy of American Poets chancellor Jane Hirshfield.
|
||||||
|
</p>
|
||||||
|
<div class="c-float-right">
|
||||||
|
<div id="3rVB5N">
|
||||||
|
<div>
|
||||||
|
|
||||||
|
</div>
|
||||||
|
</div>
|
||||||
|
</div>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="MX0Wbi">
|
||||||
|
In their work, the ideas of a fresh beginning and lingering wounds live and mingle together. They jostle against each other until both feel clear and vital and inescapable. Each on its own, each at the same time.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XwsxaF">
|
||||||
|
In “Poem of Blood,” Mahogany L. Browne dares us to just try to forget the past — and reminds us of exactly who cleans away the messiness when white people start talking about a fresh clean start. “But i’m an old broad now,” she writes, “& I got plenty of anger to lend / the days have bled from two weeks / ’til forever / & i got blood on my mind.”
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="aXp0YE">
|
||||||
|
But in Dasgupta’s “groceries on the moon,” forgetfulness becomes a vacuum, a blank space in which to inscribe and re-inscribe our old mistakes, and the mistakes of our parents. “i do not remember a great white before,” she tells us. “i do not remember the beginning. i do not / remember floating or saturn saying <em>i do</em>.”
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="kEc0xT">
|
||||||
|
Perhaps most redemptive of all is Hirshfield’s “Counting, New Year’s Morning, What Powers Yet Remain To Me.” This poem does not take place in a world without pain: Here, “the feet of the new sufferings followed the feet of the old,” and “Stone did not become apple. War did not become peace.” And yet, Hirshfield counters, “Joy still stays joy. Sequins stay sequins. Words still bespangle, bewilder.”
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="hYil90">
|
||||||
|
Art exists to help us understand two impossible ideas at the same time. The world is unbearable, but we have to bear it, and that contradiction is why we have art. More specifically, that is why we have poetry, so that what we cannot express in prose can find meaning. So that what we cannot bear in life, we can find a way to bear in verse.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="vm1fMh">
|
||||||
|
These poems for a new year are here to let words bespangle, bewilder. Even as we try for a fresh start and fail, joy still stays joy.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="8OtpXs">
|
||||||
|
<em>—Constance Grady </em>
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="7efr3e"/>
|
||||||
|
<h3 id="0PkJL4">
|
||||||
|
It Isn’t Fair, It Isn’t Right
|
||||||
|
</h3>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="HbSLvk">
|
||||||
|
<em><strong>Saeed Jones </strong></em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="h7huIe">
|
||||||
|
The color of a memory is the difference<br/>between haunted and hunted. In Mississippi, <br/>red white and blue don’t mean “remember<br/>this is America.” They mean “history is a gun<br/>and every bullet in its chamber wants you<br/>to forget.” They mean “we tried our best<br/>not to be America and failed and now we keep <br/>forgetting to forget and, anyway, who did you<br/>vote for? No need to ask us. You already know.” <br/>They mean the white man in the White House<br/>tweeted this morning that he’s being lynched.<br/>Outside my hotel — no, I’m not from around here —<br/>on the street corner, there is a plaque that tells me<br/>where I can find the body of the town’s first white<br/>settler. But it’s almost sundown and I’ve been told<br/>darkness in Mississippi is not a metaphor so I chase<br/>the shadows back into the hotel. At the bar, I beg<br/>the bartender to make me a stronger drink. He tries<br/>and he fails. I’m scared and Black and mostly sober<br/>at the hotel bar and reading an essay about lynching<br/>when some Ole Miss frat boys explode into the room,<br/>cheering in a dead language, and my heart doesn’t<br/>even wait for me to get the check. My heart is already<br/>gone. My heart is cowering in the hallway in front<br/>of my hotel room because I have the key and I just <br/>now got the check and I keep forgetting to forget<br/>that the America I was born in will not be <br/>the America in which I die.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="LIcgs3">
|
||||||
|
<em>Saeed Jones is a poet and author of the Kirkus Prize-winning memoir </em><a href="https://go.redirectingat.com?id=66960X1516588&xs=1&url=https%3A%2F%2Fbookshop.org%2Fbooks%2Fhow-we-fight-for-our-lives-a-memoir%2F9781501132742&referrer=vox.com&sref=https%3A%2F%2Fwww.vox.com%2Fthe-highlight%2F22225378%2Fpoetry-poems-saeed-jones-richard-blanco-jane-hirshfield" rel="sponsored nofollow noopener" target="_blank">How We Fight for Our Lives</a><em> and the poetry collection </em><a href="https://go.redirectingat.com?id=66960X1516588&xs=1&url=https%3A%2F%2Fbookshop.org%2Fbooks%2Fprelude-to-bruise%2F9781566893749&referrer=vox.com&sref=https%3A%2F%2Fwww.vox.com%2Fthe-highlight%2F22225378%2Fpoetry-poems-saeed-jones-richard-blanco-jane-hirshfield" rel="sponsored nofollow noopener" target="_blank">Prelude to Bruise</a><em>. </em>(Copyright 2021 by Saeed Jones.)
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="4kGLTC"/>
|
||||||
|
<h3 id="0ZuNqF">
|
||||||
|
New Year Re-Solutions, 2021
|
||||||
|
</h3>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jOuPBM">
|
||||||
|
<em><strong>Richard Blanco</strong></em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="sAHdLZ">
|
||||||
|
Stop closing the shades, let the sun glow again <br/>like a god who loves and wakes me to me <br/>in the wake of its divine light traveling millions of miles<br/>to ripple mauve and amber into my window, raise <br/>my shut eyes open, done dreaming. Breathe. <br/>Let my coffee’s steamy soul rise and bless me <br/>every day with its aroma before I take my first sip. <br/>Name each day a miracle, linger again in its mystery<br/>of possibilities. Breathe. Set the mime-hands of my watch<br/>back two minutes every day, until time and me disavow <br/>each other’s obligations. Open the newspaper, but read<br/>between the black and white lines for its lies. Breathe. <br/>Stop walking my dog, let him dog-walk me unleashed<br/>through his park. Let his nose compass me toward <br/>the smells of all I’ve stopped taking in: the sweet, ancient dank of mud and mosses, the<br/>incense of pine tree bark. Let his ears point me to listen again<br/>to all I’ve become deaf to: the wind harping through<br/>the strings of leaved branches, the opera of wrens<br/>gossiping about the weather’s secrets. Breathe. Don’t deal<br/>with the mail every day, let bills and notices pile up<br/>like a house of cards until it collapses on the kitchen counter. <br/>Take up cooking again, but add music to my recipes: <br/>sway my hips as I beat eggs to conga beats, tap my feet<br/>as I chop shallots to the staccato of piano keys, sing along<br/>as I strum the sauces slow and tender to the croon of a folk guitar. <br/>Bake all the desserts I deserve, dip my finger into the frosting first, bite into the crust, lick<br/>the plate clean, feast on my life. Breathe. Indulge <br/>myself more often alone in the living room<br/>where I’d forgotten to live. Take down my old photo albums<br/>from the shelves, stare at all the dusty years of myself<br/>in those eyes I had forgotten were mine and still love me. Breathe. Sit on the porch every<br/>night, but stop asking the moon: Who am I? Accept the moon as simply <br/>the moon, and me as simply me, just as bright<br/>and wise, just as scared and delicate as I was<br/>last year, and will be this year, and the next and <br/>the next, perfectly imperfect in the nothing of <br/>my everything, breathing as if each breath<br/>is forever my first and my last.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="HBdb9S">
|
||||||
|
<em>Richard Blanco is an engineer, writer, and award-winning poet. He’s the author of the 2019 book </em><a href="https://go.redirectingat.com?id=66960X1516588&xs=1&url=https%3A%2F%2Fbookshop.org%2Fbooks%2Fhow-to-love-a-country-poems%2F9780807043073&referrer=vox.com&sref=https%3A%2F%2Fwww.vox.com%2Fthe-highlight%2F22225378%2Fpoetry-poems-saeed-jones-richard-blanco-jane-hirshfield" rel="sponsored nofollow noopener" target="_blank">How to Love a Country</a><em> and the </em><a href="https://poets.org/poem/one-today"><em>2013 inaugural poet</em></a><em> of the United States for the inauguration of President Barack Obama; he was the first Latino to hold the role.</em>
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="Ngdizk"/>
|
||||||
|
<h3 id="JVY2gE">
|
||||||
|
Counting, New Year’s Morning, What Powers Yet Remain To Me
|
||||||
|
</h3>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4hgH3v">
|
||||||
|
<em><strong>Jane Hirshfield </strong></em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xlKNu6">
|
||||||
|
The world asks, as it asks daily: <br/><em>And what can you make, can you do, to change my deep-broken, fractured?</em><br/>I count, this first day of another year, what remains. <br/>I have a mountain, a kitchen, two hands. <br/>Can admire with two eyes the mountain, <br/>actual, recalcitrant, shifting its pebbles, sheltering foxes and beetles.<br/>Can make black-eyed peas and collards.<br/>Can make, from last year’s late-ripening persimmons, a pudding.<br/>Can climb a stepladder, change the bulb in a track light.<br/>For four years, I woke each day first to the mountain, <br/>then to the question.<br/>The feet of the new sufferings followed the feet of the old, <br/>and still they surprised.<br/>I brought salt, brought oil, to the question. Brought sweet tea, <br/>brought postcards and stamps. For four years, each day, something.<br/>Stone did not become apple. War did not become peace. <br/>Yet joy still stays joy. Sequins stay sequins. Words still bespangle, bewilder. <br/>Today, I woke without answer. <br/>The day answers, unpockets a thought from a friend—<br/><em>don’t despair of this falling world, not yet didn’t it give you the asking </em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xzNpPT">
|
||||||
|
<em>Jane Hirshfield’s ninth book of poems is </em><a href="https://www.vox.com/2020/3/21/21173809/book-review-poetry-poems-jane-hirshfield-ledger">Ledger</a><em> (</em><a href="https://go.redirectingat.com?id=66960X1516588&xs=1&url=https%3A%2F%2Fbookshop.org%2Fbooks%2Fledger-poems%2F9780525657804&referrer=vox.com&sref=https%3A%2F%2Fwww.vox.com%2Fthe-highlight%2F22225378%2Fpoetry-poems-saeed-jones-richard-blanco-jane-hirshfield" rel="sponsored nofollow noopener" target="_blank"><em>Knopf, 2020</em></a><em>). A former chancellor of the Academy of American Poets and the founder of #PoetsForScience, she was elected in 2019 to the American Academy of Arts & Sciences.</em>
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="NpdvQQ"/>
|
||||||
|
<div class="p-fullbleed-block">
|
||||||
|
<figure class="e-image">
|
||||||
|
<pre><code> <img alt="Art of a moon full and as a crescent." src="https://cdn.vox-cdn.com/thumbor/xXtXKarY6JKO4jceglUKUA5EOq8=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/22245755/Vox_PoemsForANewYear_Spot_Final.jpg" /></code></pre>
|
||||||
|
</figure>
|
||||||
|
</div>
|
||||||
|
<h3 id="Po8adi">
|
||||||
|
groceries on the moon
|
||||||
|
</h3>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="GUE6sf">
|
||||||
|
<em><strong>Meera Dasgupta</strong></em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="rnTVwp">
|
||||||
|
<em>“The emptiness of space is a blank slate, offering us the opportunity to start over, on an endless canvas that can support our continuous cycle of learnings and failings.” </em><br/> ―Aneesh Abraham, <em>Super Dense Crush Load: The Story of Man Redux</em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="a1LCRe">
|
||||||
|
I<em>. </em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="p03BPT">
|
||||||
|
<em>$2.00 - oxygen </em><br/><em>$3.99 - H2O </em><br/><em>$0.99 - space rocks </em><br/><em>$15.00 - daylight </em><br/>and so they bound towards the sun. my <br/>to-do becomes an orbital body amongst <br/>cosmic spaceships. the list lets loose like <br/>an old flag on mars.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="n7mWiR">
|
||||||
|
</p><ol start="2" style="list-style-type: upper-roman">
|
||||||
|
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"></p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jPekss">
|
||||||
|
we like to believe in alternate realities. <br/>that behind every black hole is another boy joyriding <br/>a shopping cart through aisle fifteen. a mother <br/>pulling her son away from the shelves of produce. <br/>how she bargains breath for their safe passage <br/>through a jettison of asteroids. from the ground, <br/>we wish upon them like shooting stars. <br/>there is a strength in numbers. i want to climb orion’s <br/>belt to see if there is a kingdom on the other side. <br/>if there is a god managing the checkout line from behind a <br/>curtain of satellites where thousands of heroes whisper <br/><em>the show must go on</em>. <br/>i wonder if there is an icarus pulling a sort of gravity from the <br/>moon as he falls. a single father against an empire. <br/>born of a half-life and shipwrecks. he leaps off of the edge <br/>of the universe into an ocean. here the heavens call to <br/>him. <em>find me. find us. find you. find you. </em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Hj50ef">
|
||||||
|
</p><ol start="3" style="list-style-type: upper-roman">
|
||||||
|
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"></p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="deueYB">
|
||||||
|
i do not remember a great white before. i do not <br/>remember mother banging the door straight off the<br/>hinges for the neighbor’s potpourri or when she put <br/>her hands on her hips and swore t<em>o turn on the damn </em><br/><em>lights</em>. i do not remember the beginning. i do not <br/>remember floating or saturn saying <em>i do</em>. <br/>somewhere, man bought the moon <br/>and got a supermarket on a pockmarked <br/>plain. a tower of vegetables for a sale price <br/>of 1.99. and an automated speaker system <br/>screeching melodies into a vacuum. <br/>here, silence becomes a microphone <br/>in the dark. the fridges gleam like the <br/>cold comets of space blinking back at each <br/>other in the moments between celestial <br/>explosions. <br/>they become an eye at the center of the <br/>universe. here, we can bargain with the <br/>sky.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="1lYsn5">
|
||||||
|
<em>Meera Dasgupta is the 2020 United States youth poet laureate. Born in Queens, she is a senior at Stuyvesant High School, 2020 United Nations Global Goals ambassador, Climate Speaks winner, and more. </em>
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="jZe9Rx"/>
|
||||||
|
<h3 id="8FpnxM">
|
||||||
|
Poem of Blood
|
||||||
|
</h3>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ItrEtC">
|
||||||
|
<em><strong>Mahogany L. Browne</strong></em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="EUpcLF">
|
||||||
|
The first to go are your breasts<br/>Hanging like sandbags<br/>Sad & remembering who they used to be<br/>The way a wind chime whistle <br/>can sound like a refrain: <em>stay home, daughter</em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="NLybMy">
|
||||||
|
No one wants to talk<br/>About a woman’s body during a disaster<br/>Like she’s the disaster<br/>Walking & moving slow toward the sun
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="2AqB5g">
|
||||||
|
They rather talk about the things they can’t want <br/>to change until it’s voting season, or tax season or killing season
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="qo54wD">
|
||||||
|
<em>Extra Extra!</em><br/>Another black girl is forgotten ’til dust<br/>The poets only remember her boyfriend’s name<br/>Or her brother’s shoe size<br/>they only remember the black girl body <br/>after she is gone
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="v7cap4">
|
||||||
|
The pastor reads from Genesis<br/>we nod<br/>pay tithes<br/>pass the plate <br/>& erase her initials from<br/>the scoreboard
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ey0S00">
|
||||||
|
Even the black feminist forgets she was once a girl child<br/>She closes her eyes & calls her son Prophet
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="TllhkB">
|
||||||
|
Tells Prophet to never trust women<br/>Then twists his dreads w/homemade beeswax<br/>Her fingers cracked like stomped earth<br/>Her scalp tingling w/bad news<br/>& the news say <br/>a disaster is coming <br/>call it Irma, Katrina, Rona
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4a06Pf">
|
||||||
|
America got<br/>a penchant for baby’s breath & blood milk<br/>But the blocks still hot in Brooklyn<br/>& the nannies still push strollers full of babies they ain’t birth<br/>Cause the Governor warns <em>stay home</em><br/>But the landlord echoes <em>rent due</em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="lqkpmh">
|
||||||
|
Go head America<br/>wreak havoc on the plantation <br/>& charge the sharecropper to remove the sewage
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="f7GuGg">
|
||||||
|
Stay safe<br/>Stay home?
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="1xzkL5">
|
||||||
|
Or <br/>watch the next internet sensation <br/>rely on old hip-hop t-shirts<br/>& yoga pants while<br/>Lizzo teaches her how to be human
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="MHcqk8">
|
||||||
|
Yo<br/>even the trees look at black bodies like<br/>Welcome back<br/>& the baby in the stroller ain’t heard this lullaby <br/>since they dreamt Similac <br/>brown organic raw sugar go for double the price <br/>@ whole foods<br/><em>get in line</em><br/><em>6 feet, fam</em><br/><em>don’t sleep, fam</em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="f4t3Rq">
|
||||||
|
paychecks from the government<br/>courtesy of the taxes already paid three times the amount<br/>since the last two runs around this weak ass moon
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="D3EUIC">
|
||||||
|
Gil Scott Heron was right<br/>Here we all smack slapped<br/>against the light of a smudged badge #<br/>Glint my eyes<br/>Flint in my sky<br/>everybody wants my census report<br/>but don’t nobody want to give me healthcare<br/>the water got blood in it<br/>the trees got a memory<br/>my city ain’t on fire<br/>but the fog is heavy<br/>each building swaddled in grey shit<br/>that make us sick<br/>cover your mouth<br/>cover your nose<br/>stay inside<br/>stay home<br/>or be run over<br/>& up on by the white woman who walks her dogs<br/>so close you can hear what she’s thinking<br/>6 feet who?<br/>the neighbors don’t see me<br/>but the broken man on the corner do<br/>my breasts, old with age<br/>they sag like my spirit<br/>he timberland boot & black mask bark<br/>he play brave<br/>stomp his feet<br/>& take up more sidewalk <br/>then there is concrete<br/>he howls at the sky <br/>like it aint 12pm<br/>like we ain’t in a crisis<br/>his eyes dart from my chest to my cheeks<br/>but i’m an old broad now<br/>& I got plenty of anger to lend<br/>the days have bled from two weeks<br/>’til forever<br/>& i got blood on my mind<br/>i dare him one time <br/>kiss my teeth loud<br/>then dare him w/the clearing my throat<br/>it sounds like a funeral<br/>it distracts him from the sound of key rings <br/>turning into knuckle rings<br/>but he knows the different between frail & feral<br/>he replaces his mask <br/>corks his speech <br/>& lets me pass<br/>an unhinged door on tilt<br/>‘O can you hear the wind sing?<br/><em>so close to death, so close to life, </em><br/><em>little water, little daughter, </em><br/><em>come home</em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="6pSrO0">
|
||||||
|
<em>Mahogany L. Browne is a writer, organizer, educator, and the executive director of Bowery Poetry Club and poetry coordinator at St. Francis College. She is the author of several books, including the new novel</em> <a href="https://go.redirectingat.com?id=66960X1516588&xs=1&url=https%3A%2F%2Fbookshop.org%2Fbooks%2Fchlorine-sky-9780593176405%2F9780593176399&referrer=vox.com&sref=https%3A%2F%2Fwww.vox.com%2Fthe-highlight%2F22225378%2Fpoetry-poems-saeed-jones-richard-blanco-jane-hirshfield" rel="sponsored nofollow noopener" target="_blank">Chlorine Sky</a> <em>(Crown Books for Young Readers), published in January</em>. (Copyright 2021 by Mahogany L. Browne.)
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="6hHHoK"/>
|
||||||
|
<h3 id="8wgBU2">
|
||||||
|
Eternity
|
||||||
|
</h3>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="8pvF66">
|
||||||
|
<em><strong>Alex Dimitrov</strong></em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="BYAY4C">
|
||||||
|
The light before noon and what it does to the mind.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="sWWLIF">
|
||||||
|
How you leaned against doors at parties, cried in bodegas,<br/>read bathroom graffiti and did not ask for help.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="O7gnKe">
|
||||||
|
Some nights Second Avenue seemed to go on forever.<br/>Some nights above a bar there was a plane that felt right.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="iiTbYA">
|
||||||
|
When you stood in parking lots, under the moon<br/>you went silent.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ay1d0p">
|
||||||
|
You thought about chance. History.<br/>How cruel it is to be anyone.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="TSrpm0">
|
||||||
|
“You know,” a friend told you,<br/>“we can talk about the past
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4Qo5uK">
|
||||||
|
but it’s another country<br/>without one way to get there.”
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="aXOIIu">
|
||||||
|
Maybe that’s easy.<br/>You’ve seen what fog does to bridges.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="URvKbL">
|
||||||
|
Maybe you forgot you could do anything before death.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="M3I8uD">
|
||||||
|
<em>Alex Dimitrov is the author of three books of poems, including </em><a href="https://go.redirectingat.com?id=66960X1516588&xs=1&url=https%3A%2F%2Fbookshop.org%2Fbooks%2Flove-and-other-poems-9781556595998%2F9781556595998&referrer=vox.com&sref=https%3A%2F%2Fwww.vox.com%2Fthe-highlight%2F22225378%2Fpoetry-poems-saeed-jones-richard-blanco-jane-hirshfield" rel="sponsored nofollow noopener" target="_blank">Love & Other Poems</a><em> (Copper Canyon Press), which will be published in February. He lives in New York. </em>
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="oOwDoU"/>
|
||||||
|
<h3 id="mezniK">
|
||||||
|
Poem for a New Year
|
||||||
|
</h3>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="MF2RFf">
|
||||||
|
<em><strong>Patty Crane</strong></em>
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="dMSFaA">
|
||||||
|
Glinting shards of dropped branch-ice <br/>litter the white ground under the maples,
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="E12X8X">
|
||||||
|
each glassy fragment containing<br/>its unique memory of tree, <br/>that, as the day warms, thins and spreads
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="aSLs3J">
|
||||||
|
into a gleaming tangle of light,<br/>a crazed mirror held up to the future.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XZjnol">
|
||||||
|
Hope isn’t anyone’s to give. <br/>It has to be found.<br/>And I come out here to find it,
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="2gMaqQ">
|
||||||
|
to take each moment as it comes.<br/>A kind of borrowing.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Jxi2xU">
|
||||||
|
A lone mourning dove arrives<br/>in the smoky-blue sky of its feathers, <br/>and lands, slender as a cupped hand,
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="14V95R">
|
||||||
|
among the seeds scattered on the stone walkway,<br/>its faint tracks in the snow-dust—briefly mine.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="dsSyZA">
|
||||||
|
<em>Patty Crane is the author of </em><a href="https://go.redirectingat.com?id=66960X1516588&xs=1&url=https%3A%2F%2Fbookshop.org%2Fbooks%2Fbell-i-wake-to%2F9780990633396&referrer=vox.com&sref=https%3A%2F%2Fwww.vox.com%2Fthe-highlight%2F22225378%2Fpoetry-poems-saeed-jones-richard-blanco-jane-hirshfield" rel="sponsored nofollow noopener" target="_blank">Bell I Wake To</a><em> (Zone 3 Press, 2019), </em><a href="https://go.redirectingat.com?id=66960X1516588&xs=1&url=https%3A%2F%2Fbookshop.org%2Fbooks%2Fsomething-flown%2F9780996475488&referrer=vox.com&sref=https%3A%2F%2Fwww.vox.com%2Fthe-highlight%2F22225378%2Fpoetry-poems-saeed-jones-richard-blanco-jane-hirshfield" rel="sponsored nofollow noopener" target="_blank">something flown</a><em> (Concrete Wolf, 2018), and </em><a href="https://go.redirectingat.com?id=66960X1516588&xs=1&url=https%3A%2F%2Fbookshop.org%2Fbooks%2Fbright-scythe-selected-poems-by-tomas-transtromer%2F9781941411216&referrer=vox.com&sref=https%3A%2F%2Fwww.vox.com%2Fthe-highlight%2F22225378%2Fpoetry-poems-saeed-jones-richard-blanco-jane-hirshfield" rel="sponsored nofollow noopener" target="_blank">Bright Scythe</a><em> (Sarabande Books, 2015), her translation of poems by Swedish Nobel laureate Tomas Tranströmer.</em>
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="g2PENs"/>
|
||||||
|
<div>
|
||||||
|
<div id="NYntTi">
|
||||||
|
<div>
|
||||||
|
|
||||||
|
</div>
|
||||||
|
</div>
|
||||||
|
</div>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="mHNeTO">
|
||||||
|
</p></li>
|
||||||
|
</ol></li>
|
||||||
|
</ol>
|
||||||
|
<ul>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Class of 2021: Mondaire Jones on his “jarring” start as a first-term lawmaker</strong> -
|
||||||
|
<figure>
|
||||||
|
<img alt="Rep. Mondaire Jones speaks outdoors surrounded by signs that read, “The people have spoken.”" src="https://cdn.vox-cdn.com/thumbor/tXP1fyMZC5fRN0HcUcubWk72xvA=/542x0:5098x3417/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/68696835/GettyImages_1229685695.0.jpg"/>
|
||||||
|
<figcaption>
|
||||||
|
Rep. Mondaire Jones (D-NY) was sworn in on January 3 — just three days before a mob stormed the US Capitol. For Jones and other first-term lawmakers, the first 10 days on the job have been extraordinary. | Caroline Brehman/CQ-Roll Call Inc. via Getty Images
|
||||||
|
</figcaption>
|
||||||
|
</figure></li>
|
||||||
|
</ul>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
The New York Democrat discusses the growing progressive movement in his party, and how the US Capitol riot is shaping his priorities.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Xm97aG">
|
||||||
|
</p>
|
||||||
|
<div class="c-float-left">
|
||||||
|
<figure class="e-image">
|
||||||
|
<pre><code> <img alt=" " src="https://cdn.vox-cdn.com/thumbor/YYgW4HsU995yniG4Y5QuEoQvF0Y=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/21899595/VOX_The_Highlight_Box_Logo_Horizontal.png" /></code></pre>
|
||||||
|
</figure>
|
||||||
|
</div>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="bSeTLe">
|
||||||
|
Part of <a href="https://www.vox.com/e/22014742"><strong>The “New” Issue</strong></a> of <a href="https://www.vox.com/the-highlight"><strong>The Highlight</strong></a>, our home for ambitious stories that explain our world.
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="PPKvPS"/>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="zglgpS">
|
||||||
|
Rep. Mondaire Jones (D-NY) was among those on the House floor when rioters stormed the Capitol on January 6. The newly elected Congress member was listening to remarks during the certification of the presidential election results — typically a routine, even somewhat dull proceeding in the transfer of power — when security abruptly announced the building had been breached by a mob. Jones, along with dozens of other new Democratic and Republican members, had been sworn in just three days earlier.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="zQzrtd">
|
||||||
|
“My life literally flashed before my eyes, and I know that’s true for many of the approximately 200 other members of Congress who were [there] at the time,” Jones told Vox.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="nJvfwd">
|
||||||
|
Jones has had a disquieting first few weeks. By their 10th day on the job, he and other new members — including Reps. Cori Bush (D-MO), Jamaal Bowman (D-NY), and Marie Newman (D-IL) — had endured the Capitol attack, helped finally certify election results after two months of baseless objections, and impeached the president for an unprecedented second time.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="YltvxW">
|
||||||
|
It’s been a “jarring” beginning, Jones, 33, told Vox, emphasizing that the riot — and the role some of his colleagues played in inciting it — has only strengthened his resolve to enact serious progressive reforms that “will ensure that members of Congress are sane and responsive to the American people.”
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="fks8Md">
|
||||||
|
Jones, who is one of the first openly gay Black men elected to Congress, is part of <a href="https://www.vox.com/2020/11/4/21538719/cori-bush-ritchie-torres-jamaal-bowman-election-results">a new wave of progressives elected to the House</a>, signaling just how energized the left-leaning wing of the Democratic Party continues to be. Since the election of “the Squad” in 2018, when members including Reps. Alexandria Ocasio-Cortez (D-NY) and Ayanna Pressley (D-MA) upset longtime incumbents — in part by running on policies to the left of more centrist Democrats — this young, diverse group of new lawmakers are bolstering their numbers on the Hill. Jones, campaigning on a progressive platform that won the endorsement of Ocasio-Cortez and Sens. Elizabeth Warren and Bernie Sanders, beat out competitor Adam Schleifer, a pharmaceutical heir, who outspent his campaign <a href="https://www.nytimes.com/2020/07/14/nyregion/mondaire-jones-house-primary.html">five to one</a>.
|
||||||
|
</p>
|
||||||
|
<div class="c-float-right">
|
||||||
|
<div id="enxON6">
|
||||||
|
<div>
|
||||||
|
|
||||||
|
</div>
|
||||||
|
</div>
|
||||||
|
</div>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="IHuEHm">
|
||||||
|
As their ranks continue to grow, “progressives in Congress are more powerful than they have ever been,” Jones says. A former staffer at the Justice Department during the Obama administration, <a href="https://www.nbcnews.com/feature/nbc-out/mondaire-jones-joins-ritchie-torres-first-gay-black-men-elected-n1246693&gt">Jones previously told NBC News</a> that his trajectory has come as a surprise — and that he never thought he’d get elected to Congress “growing up poor, Black and gay,” in the district he now represents.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="orwgdC">
|
||||||
|
Jones, who was elected by his peers to represent the first-term members in Democratic leadership, will also be a key advocate for the new lawmakers, and a spokesperson for their concerns in weekly meetings. As their envoy, Jones makes sure Speaker Nancy Pelosi and others are aware of where the class stands on different subjects, including impeachment.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="B9ny71">
|
||||||
|
Jones spoke with Vox about what it means to be a Capitol Hill newcomer in a strange time, and why he’s so focused on democracy reforms.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="PlBMe7">
|
||||||
|
This interview has been edited and condensed.
|
||||||
|
</p>
|
||||||
|
<h4 id="nkqPCa">
|
||||||
|
Li Zhou
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Q4Nsjl">
|
||||||
|
What has it been like to join Congress and have to process the attack on the Capitol, as well as the impeachment of President Trump, within the first two weeks of being in office?
|
||||||
|
</p>
|
||||||
|
<h4 id="gAdzcy">
|
||||||
|
Rep. Jones
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="QaVo6L">
|
||||||
|
It’s been a jarring experience. I had expected to be giving my first floor speech in connection with the For the People Act, or the Covid-19 relief bill that Joe Biden has unveiled. But instead, my first speech was in connection with the second impeachment of Donald J. Trump, after having nearly died the week before, at the hands of not just the president of the United States but his Republican co-conspirators in the House, who helped to incite last week’s violent insurrection.
|
||||||
|
</p>
|
||||||
|
<h4 id="bcBCNT">
|
||||||
|
Li Zhou
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="wGpe00">
|
||||||
|
Could you talk about your experience the day of the Capitol attack and what was going through your mind that day?
|
||||||
|
</p>
|
||||||
|
<h4 id="ijWmJH">
|
||||||
|
Rep. Jones
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="JgDdPP">
|
||||||
|
I was on the House floor with the Democratic leadership team, listening to debate during what historically has been a routine proceeding: certification of the November presidential election.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="T2EkgK">
|
||||||
|
There was an abrupt announcement by security personnel that Capitol security had been reached by the mob outside, and that we would need to lock the doors to the House chamber from the inside. Minutes later, there was a very loud banging sound at one of the doors behind me from a mob of domestic terrorists. We were told to look under our seats and to pull out gas masks in case tear gas needed to be used. We were also told to prepare to lie down on the ground in the event of gunfire.
|
||||||
|
</p>
|
||||||
|
<h4 id="CLC7YT">
|
||||||
|
Li Zhou
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4Vr5Ej">
|
||||||
|
How has this experience shaped your view of Congress — and how does that compare to expectations you had?
|
||||||
|
</p>
|
||||||
|
<h4 id="o0ptTC">
|
||||||
|
Rep. Jones
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="8eCz0H">
|
||||||
|
It makes me even more committed to enacting critical democracy reforms, including those contained in the <a href="https://thehill.com/homenews/senate/534776-senate-democrats-make-democracy-reform-first-bill-of-new-majority">For the People Act</a>, which would help elect better people to Congress. If you pass automatic voter registration to enfranchise an additional 50 million people nationally, you will get more Democrats elected to the United States Senate who will actually legislate in the best interest of the American people, rather than question the need for $2,000 survival checks, as [outgoing Georgia Republican senator] Kelly Loeffler did, because she has no commitment to helping everyday folks.
|
||||||
|
</p>
|
||||||
|
<h4 id="GEMg9T">
|
||||||
|
Li Zhou
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="zGmk7U">
|
||||||
|
What does accountability look like to you for the attack on the Capitol?
|
||||||
|
</p>
|
||||||
|
<h4 id="5QtvCP">
|
||||||
|
Rep. Jones
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="aoki2N">
|
||||||
|
I am laser-focused on holding Trump’s co-conspirators in Congress accountable both through expulsion and criminal prosecution and public shaming. Because these people need to know that they can never do what they did last week again.
|
||||||
|
</p>
|
||||||
|
<h4 id="POJs0w">
|
||||||
|
Li Zhou
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ox7PIk">
|
||||||
|
Could you talk about the new perspective and ideas you’re most excited to bring to Congress?
|
||||||
|
</p>
|
||||||
|
<h4 id="bOXmWJ">
|
||||||
|
Rep. Jones
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="9mynBS">
|
||||||
|
We need more people in office for whom policy is personal — whose lives are affected by the policies we are enacting in Washington. I’m Black, openly gay, and was raised by a single mother who relied on Section 8 housing and food stamps just to get by. That’s exactly the perspective I’ve already been bringing to our policymaking discussions.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="1ij7YE">
|
||||||
|
For too long, our political system has been designed to serve the wealthy and well-connected, but we have a real opportunity under unified Democratic control to change that and fight for a bold agenda that will improve the lives of working Americans throughout this country.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="oEqtRN">
|
||||||
|
This work clearly has to start by fixing the root of our problems: our broken democracy. The insurrection we saw on January 6 started with the myth of voter fraud, which the GOP is using to lay the foundation for another decade of suppressing the votes of people of color, working people, and young people.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="uMZ4H1">
|
||||||
|
We must pass the For the People Act (or HR 1) to fight back against the ongoing assault on our democracy; that means ending partisan gerrymandering, establishing small-dollar public financing for congressional campaigns, and automatic voter registration. We must also expand the Supreme Court, whose 6-3 hyperpartisan, conservative majority poses an existential threat to democracy itself.
|
||||||
|
</p>
|
||||||
|
<h4 id="FrE1iL">
|
||||||
|
Li Zhou
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="2ZZEUZ">
|
||||||
|
What is the top policy proposal that you plan to focus on as Congress continues to get underway?
|
||||||
|
</p>
|
||||||
|
<h4 id="Oo89Wh">
|
||||||
|
Rep. Jones
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="1D7GI2">
|
||||||
|
COVID-19 relief is the No. 1 priority. And No. 2 has to be democracy reforms. Democracy reforms will ensure that members of Congress are sane and responsive to the American people. And that we get better policies, ones that actually help working people in this country rather than the superrich.
|
||||||
|
</p>
|
||||||
|
<h4 id="dYXKWc">
|
||||||
|
Li Zhou
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4omyA5">
|
||||||
|
When it comes to Covid-19 relief, could you talk a bit about the provisions that you see as most important for the next bill to include?
|
||||||
|
</p>
|
||||||
|
<h4 id="uHz5Kx">
|
||||||
|
Rep. Jones
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="n3LnIO">
|
||||||
|
Definitely $2,000 survival checks and direct aid to states and local governments. You know, I have been supportive of monthly $2,000 checks for every adult, and monthly $1,000 checks for every child since early last spring.
|
||||||
|
</p>
|
||||||
|
<h4 id="ogldL6">
|
||||||
|
Li Zhou
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="GCU8OF">
|
||||||
|
As someone who has been elected to represent the freshman class and be part of Democratic leadership, could you talk a little bit about what that role entails?
|
||||||
|
</p>
|
||||||
|
<h4 id="q95ENO">
|
||||||
|
Rep. Jones
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="HfGgVI">
|
||||||
|
Well, I meet every week with the House Democratic leadership team, and I confirm the needs and concerns and desires of the freshman class, which is a diverse freshman class, both ideologically and in terms of life experience. It gives me an opportunity to advocate for things like the impeachment of this president, when that was still being considered.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xa2Eb9">
|
||||||
|
I was able to say I’ve spoken to every single member of the freshman class, and they’re all supportive of impeachment. It also allows me to advocate for the freshmen by pushing for them to have opportunities to lead and to legislate, so that they can show their districts that they are getting things done.
|
||||||
|
</p>
|
||||||
|
<h4 id="mbaH10">
|
||||||
|
Li Zhou
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="s3QYcm">
|
||||||
|
Given the ideological diversity that you mentioned, within both the freshman class and the Democratic caucus overall, how do you plan to keep on advancing progressive ideas?
|
||||||
|
</p>
|
||||||
|
<h4 id="QCNAo8">
|
||||||
|
Rep. Jones
|
||||||
|
</h4>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="yyCDE0">
|
||||||
|
Progressive policies are broadly popular with the American people. And in many instances, representatives in Congress have not caught up with public opinion. Progressives in Congress are more powerful than they have ever been. Our ranks have grown. And so has popular support for programs like Medicare-for-all and student debt cancellation. So I plan to work with other progressives on leveraging our votes to improve legislation.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="dsSyZA">
|
||||||
|
<em>Li Zhou is a politics and policy reporter for </em>Vox<em>. </em>
|
||||||
|
</p>
|
||||||
|
<hr class="p-entry-hr" id="bvfH9Y"/>
|
||||||
|
<div>
|
||||||
|
<div id="NYntTi">
|
||||||
|
<div>
|
||||||
|
|
||||||
|
</div>
|
||||||
|
</div>
|
||||||
|
</div>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="RbMxUy">
|
||||||
|
</p>
|
||||||
|
<h1 data-aos="fade-right" id="from-the-hindu-sports">From The Hindu: Sports</h1>
|
||||||
|
<ul>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Arsenal signs midfielder Odegaard on loan from Real Madrid</strong> - Odegaard has been at Madrid since 2015 — when he joined at the age of 16</p></li>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Two Russian tennis players banned for life for match-fixing</strong> - The case focused on “multiple incidents,” the ITIA said, including two matches they played together as doubles partners.</p></li>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>ICC ODI rankings | Virat Kohli, Rohit Sharma retain top two spots for batsmen</strong> - Jasprit Bumrah remained at the third spot in the bowler's list</p></li>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Washington Sundar: ‘Too many expectations only add to the pressure. I don’t want that’</strong> - Indian cricketer Washington Sundar seems composed despite accolades pouring his way following his Australia heroics, because he knows the road ahead is tough</p></li>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Sourav Ganguly hospitalised again with discomfort in chest, parameters stable</strong> - The 48-year-old had undergone an angioplasty earlier this month after he was diagnosed with three blocked coronary arteries.</p></li>
|
||||||
|
</ul>
|
||||||
|
<h1 data-aos="fade-right" id="from-the-hindu-national-news">From The Hindu: National News</h1>
|
||||||
|
<ul>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Never said doors for dialogue with farmers shut: Prakash Javadekar</strong> - The Union Minister said whatever decisions with regard to talks with farmers are taken, will be disclosed at the right time.</p></li>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Sivasankar’s bail plea to be heard on Feb. 1</strong> - In foreign currency smuggling case</p></li>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Kerala HC issues notice to Virat Kohli, Tamanna on plea seeking ban on online gambling in Kerala</strong> - The celebrities are the brand ambassadors of online rummy games.</p></li>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Farmers’ protests | Two unions withdraw from agitation citing Republic Day violence</strong> - Deeply pained by whatever happened during the tractor parade, says president of Bharatiya Kisan Union</p></li>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Technical glitches halt supply of food kits</strong> - Second phase of distribution of free food kits had begun on January 23</p></li>
|
||||||
|
</ul>
|
||||||
|
<h1 data-aos="fade-right" id="from-bbc-europe">From BBC: Europe</h1>
|
||||||
|
<ul>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Coronavirus: France's Sanofi to boost Pfizer vaccine supply amid EU shortages</strong> - Sanofi will produce doses of Pfizer/BioNTech which, along with AstraZeneca, has had supply problems.</p></li>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Madrid feminist mural: Councillors thwart effort to remove artwork</strong> - City councillors step in to protect the artwork, which critics argued had a "political message".</p></li>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Covid: Curfew stays despite 'scum' riots in Dutch cities</strong> - Three nights of rioting will not halt night curfews aimed at stopping coronavirus, say Dutch ministers.</p></li>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Biden raises election meddling with Putin in first phone call</strong> - The Russian leader says his first call with the new US president was "business-like and frank".</p></li>
|
||||||
|
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Spanish Armada maps 'saved for the nation'</strong> - The maps depict the famous sea battle in which the English fleet was victorious in 1588.</p></li>
|
||||||
|
</ul>
|
||||||
|
<h1 data-aos="fade-right" id="from-ars-technica">From Ars Technica</h1>
|
||||||
|
<ul>
|
||||||
|
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Basic pandemic safety limits spread in schools</strong> - Infections spread in a school system were far lower than in its surrounding towns. - <a href="https://arstechnica.com/?p=1737612">link</a></p></li>
|
||||||
|
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Warrior princess fights to save humanity in Raya and the Last Dragon trailer</strong> - "I wish to join this fellowship of butt-kickery." - <a href="https://arstechnica.com/?p=1737449">link</a></p></li>
|
||||||
|
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Plex adds game-streaming as paid add-on, completely botches the landing</strong> - $4.99/mo service needs to straighten many issues before meriting the cost. - <a href="https://arstechnica.com/?p=1737498">link</a></p></li>
|
||||||
|
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Sony adds HDMI to last year’s Android phone, charges $2,500</strong> - It's not a foldable. It's not plated in gold. It just has an HDMI port. - <a href="https://arstechnica.com/?p=1737531">link</a></p></li>
|
||||||
|
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>SpaceX adds laser links to Starlink satellites to serve Earth’s polar areas</strong> - Laser links connect Starlink satellites, reducing need for ground stations. - <a href="https://arstechnica.com/?p=1737500">link</a></p></li>
|
||||||
|
</ul>
|
||||||
|
<h1 data-aos="fade-right" id="from-jokes-subreddit">From Jokes Subreddit</h1>
|
||||||
|
<ul>
|
||||||
|
<li><strong>This morning at about 7:45, I was in a long line at a grocery store that opens at 8:00 for senior citizens only.</strong> - <!-- SC_OFF -->
|
||||||
|
<div class="md">
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
A young man came from the parking lot and tried to cut in at the front of the line, but an old lady beat him back into the parking lot with her cane.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
He returned and tried to cut in again but an old man punched him in the gut, then kicked him to the ground and rolled him away.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
As he approached the line for the third time he said, "Look, if you don't let me unlock the damn door you're never going to get in there!”
|
||||||
|
</p>
|
||||||
|
</div>
|
||||||
|
<!-- SC_ON -->
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/ClutchingMyTinkle"> /u/ClutchingMyTinkle </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/l5umjv/this_morning_at_about_745_i_was_in_a_long_line_at/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/l5umjv/this_morning_at_about_745_i_was_in_a_long_line_at/">[comments]</a></span></p></li>
|
||||||
|
<li><strong>Two guys are getting ready for a costume party...</strong> - <!-- SC_OFF -->
|
||||||
|
<div class="md">
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
But there's a catch: The host said they have to get dressed up as 'emotions.'
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
So the first guy goes home and sticks his dick in a pear.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
The second guy goes home and sticks his dick in a big bowl of custard.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
They show up at the party together and knock on the door. The host opens up the door and his mouth falls agape as he sees the two. "What the hell are you doing? What are these costumes!?"
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
The first guy looks at the host and says, "Yo, I'm deep in dis pair."
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
The second guy says, "I'm fuckin' dis custid."
|
||||||
|
</p>
|
||||||
|
</div>
|
||||||
|
<!-- SC_ON -->
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/mikeydel307"> /u/mikeydel307 </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/l5eda8/two_guys_are_getting_ready_for_a_costume_party/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/l5eda8/two_guys_are_getting_ready_for_a_costume_party/">[comments]</a></span></p></li>
|
||||||
|
<li><strong>My wife says if this post gets a 1000 likes, I can get anal on my cake day</strong> - <!-- SC_OFF -->
|
||||||
|
<div class="md">
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
Please upvote because I want this house to be spotless
|
||||||
|
</p>
|
||||||
|
</div>
|
||||||
|
<!-- SC_ON -->
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/OskarW04"> /u/OskarW04 </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/l619vl/my_wife_says_if_this_post_gets_a_1000_likes_i_can/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/l619vl/my_wife_says_if_this_post_gets_a_1000_likes_i_can/">[comments]</a></span></p></li>
|
||||||
|
<li><strong>What’s the Most Stupid Animal in the Jungle?</strong> - <!-- SC_OFF -->
|
||||||
|
<div class="md">
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
The Polar Bear
|
||||||
|
</p>
|
||||||
|
</div>
|
||||||
|
<!-- SC_ON -->
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/PhummyLW"> /u/PhummyLW </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/l5uotm/whats_the_most_stupid_animal_in_the_jungle/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/l5uotm/whats_the_most_stupid_animal_in_the_jungle/">[comments]</a></span></p></li>
|
||||||
|
<li><strong>A man applies for a government job</strong> - <!-- SC_OFF -->
|
||||||
|
<div class="md">
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
A man goes to the Post Office to apply for a job.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
The interviewer asks him, "Are you allergic to anything?"
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
He replies, "Yes, caffeine. I can't drink coffee."
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
"OK, have you ever been in the military service?"
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
"Yes," he says, "I was in Afghanistan for one tour."
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
The interviewer says, "That will give you 5 extra points toward employment."
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
Then he asks, "Are you disabled in any way?"
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
The guy says, "Yes. A bomb exploded near me and I lost both my testicles.
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
The interviewer grimaces and then says, "Okay. You've got enough points for me to hire you right now."
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
"Our normal hours are from 8 am to 4 pm. You can start tomorrow at 10 am and plan on starting at 10 am every day."
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
The guy is puzzled and asks, "If the work hours are from 8 am to 4 pm, why don't you want me here until 10 am?"
|
||||||
|
</p>
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
|
||||||
|
"This is a government job," the interviewer says. "For the first two hours, we just stand around drinking coffee and scratching our balls. So no point in your coming in for that."
|
||||||
|
</p>
|
||||||
|
</div>
|
||||||
|
<!-- SC_ON -->
|
||||||
|
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/Cherbotsky"> /u/Cherbotsky </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/l5pbf7/a_man_applies_for_a_government_job/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/l5pbf7/a_man_applies_for_a_government_job/">[comments]</a></span></p></li>
|
||||||
|
</ul>
|
||||||
|
|
||||||
|
|
||||||
|
<script>AOS.init();</script></body></html>
|
||||||
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Reference in New Issue