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+ + + ++During the COVID-19 pandemic, many countries and regions investigated the potential use of wastewater-based disease surveillance as an early warning system. Initially, methods were created to detect the presence of SARS-CoV-2 RNA in wastewater. Investigators have since conducted extensive studies to examine the link between viral concentration in wastewater and COVID-19 cases in areas served by sewage treatment plants over time. However, only a few reports have attempted to create predictive models for hospitalizations at county-level based on SARS-CoV-2 RNA concentrations in wastewater. This study implemented a linear mixed-effects model that observes the association between levels of virus in wastewater and county-level hospitalizations. The model was then utilized to predict short-term county-level hospitalization trends in 21 counties in California based on data from March 21, 2022, to May 21, 2023. The modeling framework proposed here permits repeated measurements as well as fixed and random effects. The model that assumed wastewater data as an input variable, instead of cases or test positivity rate, showed strong performance and successfully captured trends in hospitalizations. Additionally, the model allows for the prediction of SARS-CoV-2 hospitalizations two weeks ahead. Forecasts of COVID-19 hospitalizations could provide crucial information for hospitals to better allocate resources and prepare for potential surges in patient numbers. +
++Introduction: Model projections of COVID-19 incidence into the future help policy makers about decisions to implement or lift control measures. During 2020, policy makers in the Netherlands were informed on a weekly basis with short-term projections of COVID-19 intensive care unit (ICU) admissions. Here we present the model and the procedure by which it was updated. Methods: the projections were produced using an age-structured transmission model. A consistent, incremental update procedure that integrated all new surveillance and hospital data was conducted weekly. First, up-to-date estimates for most parameter values were obtained through re-analysis of all data sources. Then, estimates were made for changes in the age-specific contact rates in response to policy changes. Finally, a piecewise constant transmission rate was estimated by fitting the model to reported daily ICU admissions, with a change point analysis guided by Akaike9s Information Criterion. Results: The model and update procedure allowed us to make mostly accurate weekly projections, accounting for recent and future policy changes, and to adapt the estimated effectiveness of the policy changes based only on the natural accumulation of incoming data. Discussion: The model incorporates basic epidemiological principles and most model parameters were estimated per data source. Therefore, it had potential to be adapted to a more complex epidemiological situation, as it would develop after 2020. +
+A Randomized Trial Evaluating a mRNA VLP Vaccineās Immunogenicity and Safety for COVID-19 - Conditions: COVID-19; SARS-CoV-2 Infection
Interventions: Biological: AZD9838; Biological: Licensed mRNA vaccine
Sponsors: AstraZeneca
Not yet recruiting
Effect of Metformin in Reducing Fatigue in Long COVID in Adolescents - Conditions: Long COVID
Interventions: Drug: Metformin; Other: Placebo
Sponsors: Trust for Vaccines and Immunization, Pakistan
Not yet recruiting
āThe Effect of Aerobic Exercise and Strength Training on Physical Activity Level, Quality of Life and Anxiety-Stress Disorder in Young Adults With and Without Covid-19ā - Conditions: COVID-19
Interventions: Behavioral: Aerobic Exercise and Strength Training
Sponsors: Pamukkale University
Active, not recruiting
Vale+TĆŗ Salud: Corner-Based Randomized Trial to Test a Latino Day Laborer Program Adapted to Prevent COVID-19 - Conditions: COVID-19
Interventions: Behavioral: COVID-19 Group Problem Solving; Behavioral: Standard of Care; Behavioral: Booster session
Sponsors: The University of Texas Health Science Center, Houston; National Institute on Minority Health and Health Disparities (NIMHD)
Recruiting
Safety Study of SLV213 for the Treatment of COVID-19. - Conditions: COVID-19
Interventions: Other: Placebo for SLV213; Drug: SLV213
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID)
Not yet recruiting
Collection of Additional Biological Samples From Potentially COVID-19 Patients for Monitoring of Biological Parameters Carried Out as Part of the Routine - Conditions: SARS CoV 2 Infection
Interventions: Diagnostic Test: RIPH2
Sponsors: CerbaXpert
Not yet recruiting
Mitigating Mental and Social Health Outcomes of COVID-19: A Counseling Approach - Conditions: Social Determinants of Health; Mental Health Issue; COVID-19
Interventions: Behavioral: Individual counseling; Behavioral: Group counseling; Other: Resources
Sponsors: Idaho State University
Not yet recruiting
Promoting Engagement and COVID-19 Testing for Health - Conditions: COVID-19
Interventions: Behavioral: COVID-19 Test Reporting; Behavioral: Personalized Nudges via Text Messaging; Behavioral: Non-personalized Nudges via Text Messaging
Sponsors: Emory University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Morehouse School of Medicine; Georgia Institute of Technology
Not yet recruiting
Development and Qualification of Methods for Analyzing the Mucosal Immune Response to COVID-19 - Conditions: Certain Disorders Involving the Immune Mechanism
Interventions: Biological: Sampling; Biological: PCR (polymerase chain reaction) SARS-CoV-2
Sponsors: University Hospital, Tours
Not yet recruiting
Water-based Activity to Enhance Recovery in Long COVID - Conditions: Long COVID
Interventions: Behavioral: WATER+CT; Behavioral: Usual Care
Sponsors: VA Office of Research and Development
Not yet recruiting
Efficacy of Two Therapeutic Exercise Modalities for Patients With Persistent COVID - Conditions: Persistent COVID-19
Interventions: Other: exercise programe
Sponsors: Facultat de ciencies de la Salut Universitat Ramon Llull
Recruiting
Performance Evaluation of the Lucira COVID-19 & Flu Test - Conditions: COVID-19; Influenza
Interventions: Device: Lucira COVID-19 & Flu Test
Sponsors: Lucira Health Inc
Completed
Cognitive Rehabilitation in Post-COVID-19 Syndrome - Conditions: Post-COVID-19 Syndrome
Interventions: Behavioral: CO-OP Procedures; Behavioral: Inactive Control Group
Sponsors: University of Missouri-Columbia; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Not yet recruiting
Robotic Assisted Hand Rehabilitation Outcomes in Adults After COVID-19 - Conditions: Robotic Exoskeleton; Post-acute Covid-19 Syndrome; Rehabilitation Outcome; Physical And Rehabilitation Medicine
Interventions: Device: Training with a Robotic Hand Exoskeleton
Sponsors: University of Valladolid; Centro Hospitalario Padre Benito Menni
Completed
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling - Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 has caused millions of deaths since emerging in 2019. Innate immune antagonism by lethal CoVs such as SARS-CoV-2 is crucial for optimal replication and pathogenesis. The conserved nonstructural protein 15 (nsp15) endoribonuclease (EndoU) limits activation of double-stranded (ds)RNA-induced pathways, including interferon (IFN) signaling, protein kinase R (PKR), and oligoadenylate synthetase/ribonuclease L (OAS/RNase L) during diverse CoVā¦
Application of machine learning models to identify serological predictors of COVID-19 severity and outcomes - Critically ill people with COVID-19 have greater antibody titers than those with mild to moderate illness, but their association with recovery or death from COVID-19 has not been characterized. In 178 COVID-19 patients, 73 non-hospitalized and 105 hospitalized patients, mucosal swabs and plasma samples were collected at hospital enrollment and up to 3 months post-enrollment (MPE) to measure virus RNA, cytokines/chemokines, binding antibodies, ACE2 binding inhibition, and Fc effector antibodyā¦
C1 esterase inhibitor-mediated immunosuppression in COVID-19: Friend or foe? - From asymptomatic to severe, SARS-CoV-2, causative agent of COVID-19, elicits varying disease severities. Moreover, understanding innate and adaptive immune responses to SARS-CoV-2 is imperative since variants such as Omicron negatively impact adaptive antibody neutralization. Severe COVID-19 is, in part, associated with aberrant activation of complement and Factor XII (FXIIa), initiator of contact system activation. Paradoxically, a protein that inhibits the three known pathways of complementā¦
The association between BIS/BAS and fear of COVID-19 infection among women - CONCLUSIONS: The BIS weakly, but significantly correlated with womenās fear of their loved ones being infected by COVID-19. This study highlights the possible role of the BIS mechanism in womenās response to COVID-19-related fear, but only when the threat affects loved ones. Comparative studies between men and women are necessary.
Catalytic Antibodies May Contribute to Demyelination in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - Here we report preliminary data demonstrating that some patients with myalgic encephalomyelitis/chronic fatiguesyndrome (ME/CFS) may have catalytic autoantibodies that cause the breakdown of myelin basic protein (MBP). We propose that these MBP-degradative antibodies are important to the pathophysiology of ME/CFS, particularly in the occurrence of white matter disease/demyelination. This is supported by magnetic resonance imagining studies that show these findings in patients with ME/CFS andā¦
Achievement Emotions of Medical Students: Do They Predict Self-regulated Learning and Burnout in an Online Learning Environment? - BACKGROUND: Achievement emotions have been proven as important indicators of studentsā academic performance in traditional classrooms and beyond. In the online learning contexts, previous studies have indicated that achievement emotions would affect studentsā adoption of self-regulated learning strategies and further predict their learning outcomes. However, the pathway regarding how different positive and negative achievement emotions might affect studentsā burnout through self-regulatedā¦
Linoleic acid: a natural feed compound against porcine epidemic diarrhea disease - Porcine epidemic diarrhea virus (PEDV) is a pig coronavirus that causes severe diarrhea and high mortality in piglets, but as no effective drugs are available, this virus threatens the pig industry. Here, we found that the intestinal contents of specific pathogen-free pigs effectively blocked PEDV invasion. Through proteomic and metabolic analyses of the intestinal contents, we screened 10 metabolites to investigate their function and found that linoleic acid (LA) significantly inhibited PEDVā¦
Platelet factor 4(PF4) and its multiple roles in diseases - Platelet factor 4 (PF4) combines with heparin to form an antigen that could produce IgG antibodies and participate in heparin-induced thrombocytopenia (HIT). PF4 has attracted wide attention due to its role in novel coronavirus vaccine-19 (COVID-9)-induced immune thrombotic thrombocytopenia (VITT) and cognitive impairments. The electrostatic interaction between PF4 and negatively charged molecules is vital in the progression of VITT, which is similar to HIT. Emerging evidence suggests itsā¦
Design of MERS-CoV entry inhibitory short peptides based on helix-stabilizing strategies - Interaction between Middle East respiratory syndrome coronavirus (MERS-CoV) spike (S) protein heptad repeat-1 domain (HR1) and heptad repeat-2 domain (HR2) is critical for the MERS-CoV fusion process. This interaction is mediated by the Ī±-helical region from HR2 and the hydrophobic groove in a central HR1 trimeric coiled coil. We sought to develop a short peptidomimetic to act as a MERS-CoV fusion inhibitor by reproducing the key recognition features of HR2 helix. This was achieved by the use ofā¦
A phenothiazine urea derivative broadly inhibits coronavirus replication via viral protease inhibition - Coronavirus (CoV) replication requires efficient cleavage of viral polyproteins into an array of non-structural proteins involved in viral replication, organelle formation, viral RNA synthesis, and host shutoff. Human CoVs (HCoVs) encode two viral cysteine proteases, main protease (M^(pro)) and papain-like protease (PL^(pro)), that mediate polyprotein cleavage. Using a structure-guided approach, a phenothiazine urea derivative that inhibits both SARS-CoV-2 M^(pro) and PL^(pro) protease activityā¦
Inhibition of furin-like enzymatic activities and SARS-CoV-2 infection by osthole and phenolic compounds with aryl side chains - Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread as a pandemic and caused damage to peopleās lives and countriesā economies. The spike (S) protein of SARS-CoV-2 contains a cleavage motif, Arg-X-X-Arg, for furin and furin-like enzymes at the boundary of the S1/S2 subunits. Given that cleavage plays a crucial role in S protein activation and viral entry, the cleavage motif was selected as the target. Our previous fluorogenicā¦
Efficient SARS-CoV-2 infection antagonization by rhACE2 ectodomain multimerized onto the Avidin-Nucleic-Acid-NanoASsembly - Nanodecoy systems based on analogues of viral cellular receptors assembled onto fluid lipid-based membranes of nano/extravescicles are potential new tools to complement classic therapeutic or preventive antiviral approaches. The need for lipid-based membranes for transmembrane receptor anchorage may pose technical challenges along industrial translation, calling for alternative geometries for receptor multimerization. Here we developed a semisynthetic self-assembling SARS-CoV-2 nanodecoy byā¦
Predictions based on inflammatory cytokine profiling of Egyptian COVID-19 with 2 potential therapeutic effects of certain marine-derived compounds - CONCLUSION: The investigated inflammatory biomarkers in Egyptian COVID-19 patients showed a strong correlation between IL6, TNF-Ī±, NF-ĪŗB, CRB, DHL, and ferritin as COVID-19 biomarkers and determined the severity of the infection. Also, the oxidative /antioxidant showed good biomarkers for infection recovery and progression of the patients.
Circularized Nanodiscs for Multivalent Mosaic Display of SARS-CoV-2 Spike Protein Antigens - The emergence of vaccine-evading SARS-CoV-2 variants urges the need for vaccines that elicit broadly neutralizing antibodies (bnAbs). Here, we assess covalently circularized nanodiscs decorated with recombinant SARS-CoV-2 spike glycoproteins from several variants for eliciting bnAbs with vaccination. Cobalt porphyrin-phospholipid (CoPoP) was incorporated into the nanodisc to allow for anchoring and functional orientation of spike trimers on the nanodisc surface through their His-tagā¦.
Comparative Immune Response after Vaccination with SOBERANAĀ® 02 and SOBERANAĀ® plus Heterologous Scheme and Natural Infection in Young Children - (1) Background: In children, SARS-CoV-2 infection is mostly accompanied by mild COVID-19 symptoms. However, multisystem inflammatory syndrome (MIS-C) and long-term sequelae are often severe complications. Therefore, the protection of the pediatric population against SARS-CoV-2 with effective vaccines is particularly important. Here, we compare the humoral and cellular immune responses elicited in children (n = 15, aged 5-11 years) vaccinated with the RBD-based vaccines SOBERANA^(Ā®) 02 andā¦
When Your Own Book Gets Caught Up in the Censorship Wars - I had envisioned book bans as modern morality playsābut the reality was far more complicated. - link
The Death of a Relic Hunter - Bill Erquitt was an unforgettable character among Georgiaās many Civil War enthusiasts. After he died, his secrets came to light. - link
The Road to Dubai - The latest round of international climate negotiations is being held in a petrostate. What could go wrong? - link
Should People Have the Right to Say Awful Things Without Facing Legal Consequences? - Those who want to curtail freedom of speech do not log the debits and credits of censorship, nor do they care about the balance of normsāthey act when they have power. - link
Bradley Cooper: Conducting Is the āScariest Thing Iāve Ever Doneā - Bradley Cooper tells David Remnick that he has spent his life preparing for his role in āMaestroā as the iconic conductor Leonard Bernsteināand it shows. - link
+At the very moment the Supreme Court appears to be moderating on voting rights, GOP judges are going after Americaās most important voting rights law. +
++The Supreme Court, after a long period of hostility toward any claim brought under the federal Voting Rights Act, recently signaled that this hostility has limits. Last June, the Court surprised nearly everyone who follows voting rights litigation by declaring Alabamaās racially gerrymandered maps illegal and ordering the state to draw a second majority-Black congressional district. +
++Yet if the Supreme Courtās June decision in Allen v. Milligan (2023) was supposed to be a signal that the justices intend to keep at least some safeguards against racism in elections in place, several Republican appointees to the lower courts missed the memo. Last week, as most Americans were thinking about their Thanksgiving dinners, a pair of federal appeals courts handed down some of the sharpest attacks on the Voting Rights Act ā the landmark 1965 law prohibiting race discrimination in US elections ā in the lawās history. +
++The first was an opinion from a divided panel of the United States Court of Appeals for the Eighth Circuit that, if affirmed by the Supreme Court, would virtually destroy the Voting Rights Act. +
++The Eighth Circuitās opinion in Arkansas State Conference NAACP v. Arkansas Public Policy Panel, written by Trump Judge David Stras, would strip private parties of their ability to file lawsuits enforcing the Voting Rights Act and establish that all such lawsuits must be brought by the Justice Department. +
++This decision is dead wrong, and it conflicts with decades of precedent. +
++As Judge Lavenski Smith notes in dissent, over the past 40 years litigants have brought 182 successful lawsuits under the Voting Rights Act. Only 15 were brought solely by the DOJ. So, if Strasās unusual reading of the law were correct, nearly 92 percent of all of these victorious lawsuits should have ended in defeat for the plaintiffs. +
++Then, on the day after Thanksgiving, the 11th Circuit handed down its own decision attacking a core principle of the Voting Rights Act. Trump Judge Elizabeth Branchās opinion in Rose v. Secretary isnāt quite as aggressive as Strasās wholesale attack on the landmark law ā while Strasās opinion could potentially neutralize the Voting Rights Act in its entirety, Branchās opinion would only permit states to use one particular method that has historically been used to disenfranchise voters of color. +
++Specifically, Rose asks whether states may elect multi-member bodies such as a legislature using an āat-largeā scheme where every member of the body is elected by the state as a whole. As the Supreme Court warned in Rogers v. Lodge (1982), āat-large voting schemes and multimember districts tend to minimize the voting strength of minority groups by permitting the political majority to elect all representatives of the district.ā Thus, in a state like Georgia, where white people make up nearly 60 percent of the population, white voters can join together to prevent the Black minority from electing anyone to a state board if the state uses an at-large system to elect those board members. +
++Nevertheless, Branchās decision in Rose would make it extraordinarily simple for states to use at-large systems that could not be challenged in court ā even though both the Supreme Court and lower federal courts have repeatedly permitted challenges to at-large systems that lock racial minority groups out of power. Branchās opinion even lists nearly a dozen cases challenging such at-large systems. +
++These decisions, both by Trump judges, should alarm anyone who cares about voting rights. While the Courtās decision in Milligan suggests that, at the very least, Strasās attempt to nuke the Voting Rights Act is likely to be reversed by the current panel of justices, judges like Stras and Branch are hardly outliers among the right-wing advocates and Federalist Society stalwarts that Trump appointed. If anything, their records suggest they are right in the heartland of modern-day Republican appointees to the federal bench. +
++And that means that, even if this Supreme Court resists these new efforts to destroy the one federal law that likely did more than any other to end Jim Crow, there is a serious risk that the entire law could fall if Republicans ā such as Trump himself ā get to appoint more judges to the Supreme Court. +
++The specific question in the Arkansas case is whether Section 2 of the Voting Rights Act, the provision that allows lawsuits challenging racially discriminatory voting practices by states, may be enforced by private parties or if these lawsuits may only be brought by the Justice Department. For decades, courts ā including the Supreme Court ā have allowed private parties to bring such suits. +
++And, as Judge Smith wrote in his dissent, 167 of these private plaintiffs have brought successful lawsuits under Section 2, including the plaintiffs in the Milligan case. +
++To understand why Strasās opinion departing from this longstanding consensus is wrong, itās helpful to understand the Supreme Courtās decisions governing what are known as āimplied rights of action.ā +
++Sometimes, federal laws contain language explicitly stating that private parties have a āright of actionā (meaning a right to sue) against certain defendants. Other times, a legal document may explicitly state that private parties may not file certain lawsuits. It is common, for example, for presidential executive orders to contain language stating that the order does not ācreate any right or benefitā which can be enforced in federal court. +
++But what if a law does not state either way whether it permits private parties to bring lawsuits to enforce that law? In short, the answer to this question has changed over time. In J.I. Case v. Borak (1964), decided the year before the Voting Rights Act became law, the Supreme Court held that courts should read federal statutes generously to allow the parties who benefit from those laws to bring federal lawsuits. +
++āIt is the duty of the courts,ā the Supreme Court held in Borak, āto be alert to provide such remedies as are necessary to make effective the congressional purpose.ā The Supreme Court explained a few years later, in a Voting Rights Act case, that āa federal statute passed to protect a class of citizens, although not specifically authorizing members of the protected class to institute suit, nevertheless implied a private right of action.ā +
++So under the rules that existed when the Voting Rights Act was written in 1965, it clearly should be read to permit private lawsuits. +
++That said, post-1965 decisions, handed down by more conservative courts, have held that the judiciary should be more reluctant to find implied rights of action within a federal statute than the Court was in Borak. The most significant of these decisions is probably Alexander v. Sandoval (2001), which held that āstatutes that focus on the person regulated rather than the individuals protected create āno implication of an intent to confer rights on a particular class of persons.āā +
++So, under Sandoval, if a federal law uses language like āno state shall do Xā instead of āall persons have a right to X,ā courts typically should not permit private lawsuits under that statute. +
++The thrust of Strasās opinion in the Arkansas case is that Sandoval should be read retroactively to neutralize the right of private parties to sue under the Voting Rights Act. This decision is fundamentally unfair to Congress, as Sandoval was handed down nearly four decades after the Voting Rights Act became law. So Congress couldnāt possibly have known that it had to write the law in a particular way if it wanted to authorize private lawsuits. +
++Itās also not entirely clear that Sandoval cuts off private suits under the Voting Rights Act, even if it is applied retroactively. Recall that the inquiry under Sandoval hinges on whether a statute refers to the entity it seeks to regulate, rather than the āindividuals protectedā by that statute. But the Voting Rights Act uses both kinds of language. +
++While the relevant provision starts with the phrase āno voting qualification or prerequisite to voting or standard, practice, or procedure shall be imposed or applied by any State,ā it goes on to forbid any voting practice āwhich results in a denial or abridgement of the right of any citizen of the United States to vote.ā +
++Sandoval, moreover, also states that āthe judicial task is to interpret the statute Congress has passed to determine whether it displays an intent to create not just a private right but also a private remedy,ā and that āstatutory intent on this latter point is determinative.ā And there is overwhelming evidence that Congress intended to create a private right of action when it wrote the Voting Rights Act. +
++Again, Congress wrote the law against the backdrop of decisions like Borak, which emphasized that private parties should generally be allowed to sue to enforce their legal rights. Federal courts have understood the law to permit private suits at least as far back as the 1960s. And Congress has amended the VRA multiple times, but itās never questioned the longstanding assumption that the law permits private lawsuits. +
++Federal civil rights law also includes a catch-all statute, known as āSection 1983,ā which permits state officials to be sued if they deprive someone of āany rights, privileges, or immunities secured by the Constitution and laws.ā +
++The Voting Rights Act law secures a right to be free from race discrimination in elections. That means that, even if the Voting Rights Act itself doesnāt authorize a private cause of action, Section 1983 permits lawsuits seeking to enforce the rights created by the Voting Rights Act. Indeed, the Supreme Court just reaffirmed in Health and Hospital Corporation v. Talevski (2023) that Section 1983 gives private individuals broad authority to sue to enforce their statutory rights. +
++Strasās approach, in other words, isnāt simply wrong, it is obviously wrong. And his Arkansas opinion will lead to disastrous results if it is not reversed. As the Supreme Court warned in Allen v. State Board of Elections (1969), the Voting Rights Act ācould be severely hampered ā¦ if each citizen were required to depend solely on litigation instituted at the discretion of the Attorney General.ā Among other things, āthe Attorney General has a limited staff and often might be unable to uncover quicklyā new state policies that target voters of color. +
++In fact, Strasās approach would likely shut down the Voting Rights Act almost in its entirety whenever Republicans control the White House. During the entire Trump administration, the Justice Departmentās voting section brought only one lawsuit alleging discrimination under the Voting Rights Act ā and that was a fairly minor suit alleging that the method of electing school board members in a South Dakota school district ādilutes the voting strength of American Indian citizens.ā +
++The one good thing that can be said about Judge Branchās opinion in Rose is that, unlike Strasās Arkansas opinion, it doesnāt attempt to destroy the Voting Rights Act almost in its entirety. But the Rose opinion is still wrong, and it betrays a hostility toward federal voting rights that raises serious questions about whether the three judges who decided the Rose case have any familiarity with American civil rights history. +
++As noted above, courts fairly frequently hear, and sometimes strike down, at-large voting systems because of their impact on voters of color. While such systems are not always illegal, they run afoul of the Voting Rights Act when, in the words of the statute, an at-large system āresults in a denial or abridgement of the right of any citizen of the United States to vote on account of race or color.ā +
++Branchās opinion, however, would likely greenlight such systems whenever they are used on a statewide basis, rather than by a county, municipality, or other, smaller governmental body. Though Branch acknowledges many decisions where courts have struck down at-large systems used by city councils, school boards, and the like, she claims that Voting Rights Act lawsuits have ānever been used to invalidate a statewide election system on vote dilution grounds.ā +
++That may well be true, but it is a meaningless distinction. The Voting Rights Actās text applies equally to āany Stateā as well as any āpolitical subdivisionā of a state. So the statute applies with equal force both to statewide practices that violate the law and to similar practices by city councils or other smaller bodies. Branchās opinion is entirely at odds with the lawās text. +
++To this, Branch replies that āgeneral principles of federalismā require her to uphold the state of Georgiaās practice of electing all five members of its Public Service Commission on an at-large basis ā āfederalismā refers to the idea that states retain some degree of sovereignty that cannot be taken from them by a federal law. +
++But the concept of states rights, as anyone who has even the most basic understanding of American civil rights history will understand, has no place whatsoever in a Voting Rights Act lawsuit. The entire purpose of the Voting Rights Act was to prevent Jim Crow states, including Georgia, from running their elections in ways that depart from the federal commitment to racial equality. +
++The Constitution, moreover, is quite clear that Congress ā and not the state of Georgia ā has the final say on how elections will be conducted in that state, at least when race discrimination is an issue. The 15th Amendment prohibits states from denying or abridging the right to vote āon account of race, color, or previous condition of servitude,ā and it provides that āCongress shall have the power to enforce this article by appropriate legislation.ā +
++To justify her decision, Branch relies heavily on the 11th Circuitās decision in Nipper v. Smith (1994), a Voting Rights Act case that challenged Floridaās practice of having all of the voters within a given judicial circuit elect the judges in that circuit ā that is, on an at-large basis. The plaintiffs in Nipper argued that these judicial circuits should be chopped up into sub-districts, with each sub-district electing a subset of the circuitās judges. +
++But Nipper rejected this solution in no small part because it would have undermined the Voting Rights Actās goal of fostering racial equality. If Florida judges were elected by sub-districts, the court warned, that would mean that judges in majority-Black sub-districts would be chosen by Black voters, but judges in majority-white sub-districts would be chosen by white voters. This system, the court feared, would be ādetrimental to ā¦ fair and impartial justiceā because all of these judges would continue to have jurisdiction over the entire circuit ā and thus judges elected solely by white voters would continue to hold authority over Black litigants. +
++Nipper, in other words, rejected a cure that was worse than the disease. It held that federal courts should not break up an at-large system of electing judges if the solution would lead to more judges being elected by insular white majorities who may very well be hostile to the interests of Black voters. Thatās a far cry from Branchās claim that vague appeals to āfederalismā justify weakening a statute whose entire purpose is to strip states of some of their authority over election administration. +
++Moreover, while Branchās opinion, on its face, is limited to Voting Rights Act challenges to statewide at-large systems, her freewheeling appeal to āfederalismā has serious implications for all kinds of voting rights lawsuits by suggesting that states have some ill-defined right to resist voting rights legislation that school boards or city councils do not. +
++If Arkansas and Rose had been handed down a year ago, they would have seemed like an effort by lower courts to move in the same direction the Supreme Court has been moving for several years. +
++Prior to Milligan, the Roberts Courtās record in Voting Rights Act cases was almost unrelentingly hostile. In Shelby County v. Holder (2013), the Courtās Republican appointees simply made up a doctrine ā āthe principle that all States enjoy equal sovereigntyā ā that is never once mentioned in the Constitution in order to justify striking down a key provision of the Voting Rights Act. In Brnovich v. DNC (2021), the Supreme Court similarly made up a bunch of limits on the Voting Rights Act that cannot be found anywhere in any legal text, such as a strong presumption that voting restrictions that were in place in 1982 are lawful. +
++Faced with these precedents ā decisions that, in Justice Elena Kaganās words, āmostly inhabit[ ] a law-free zoneā ā Strasās and Branchās disregard for longstanding law might be understandable. After all, the Roberts Court frequently hands down Voting Rights Act decisions that do not even attempt to ground their holding in constitutional or statutory text. +
++But Milligan suggests that the Supreme Court may be moving away from this hostility. Unlike Shelby County and Brnovich, Milligan hewed closely to longstanding law. As the Court said in Milligan when it affirmed a lower court decision striking down Alabamaās gerrymandered maps, that decision āfaithfully applied our precedents.ā +
++At the very least, Strasās and Branchās opinions are likely to force the Supreme Court to resolve this tension between Milligan and its previous, less justifiable decisions undercutting the Voting Rights Act. Neither lower court judgeās decision is persuasive. But they are entirely consistent with the law-free zone the Supreme Court seemed to erect around the Voting Rights Act in cases like Shelby County and Brnovich. +
+Regular giving, even in small amounts, can save lives. +
++Itās Giving Tuesday, and itās time for me to do what I do on Vox every Giving Tuesday: encourage people to give more money to effective charities. +
++Over years of doing this, Iāve gotten a long and familiar list of objections. I decided this Giving Tuesday to try my best to answer them. +
++I am asking you to give 10 percent of your pretax income to a charity that saves lives. I personally give my 10 percent to GiveWellās top charities fund, which redistributes it to highly effective global health charities like the Malaria Consortium and Helen Keller International. GiveWell estimates that for every $5,000 gift, these charities will save one human life. +
++I think of GiveWell as like the charity version of an index fund: Itās a rigorous, impartial recommender that you can donate to without having to pick and choose individual causes. Itās also, disclosure, an advertiser on Vox podcasts, though Iāve been using it since long before that was true. +
++Itās significant. For the average American household, which has an income of roughly $75,000, itās a $7,500 commitment. Thatās a real bite, but itās also more than enough to save a life. +
++Thatās fair! Can you do 5 percent? +
++I would go as low as 1 percent! +
++Well, every five years you would. And if you want to do more good, we can always go back to 10 percent! +
++For sure: The practice of tithing in many world religions is a key inspiration here. The twist is that Iām suggesting tithing not to religious institutions but to highly effective charities (which could be religious or not ā itās not their beliefs that matter, but their effectiveness). +
++Because thereās a huge, huge difference between what the most and least effective charities can accomplish with donations. You might think that charities are like brands of dish soapā¦ +
++Itās an analogy, give me a second. The absolute best dish soap is probably, at most, a tiny bit better than the average brand, right? I mean itās just soap. Even Wirecutter says āyou probably canāt go wrong with most name-brand dish detergents.ā +
++But really, charities are more like chefās knives. The difference between the best and worst knife is enormous and affects the entire process of cooking, or so it has been explained to me by superior cooks. Itās the difference between an enjoyable time in the kitchen versus pure drudgery (and a heightened chance you inadvertently chop off your fingertip). +
++What it has to do with charity is that the vast majority of nonprofits have no evidence of positive impact at all, and even charities brave enough to agree to rigorous tests of their impact see widely variable effectiveness. In global development, something like 60 to 70 percent of interventions tested show no results at all, which effectively means the money donated could have just been thrown down a hole. +
++And among those that do show results, the size of the impact varies drastically. The researcher Benjamin Todd has looked into these questions a lot, examining nine different databases of program impact, and found that in every context, from US social policy to global health to the UKās National Health Service to estimates of climate policies, the results are āfat-tailed.ā Thatās statistics talk for the conclusion that the best interventions are much, much better than the average interventions. +
++It depends, but here are a couple of examples: The most cost-effective treatments examined by Britainās National Health Service were 120 times more effective than the median treatment. A World Bank study found the most effective interventions in global health were 38 times more effective than the median ones. +
++Because it lets you do a lot more good. Suppose youāre giving $7,500 a year. If you gave that to an average global health program, youād be providing 30 more total years of healthy life to a few people, per the World Bank data. +
++Itās great. But If you put that money toward one of the 2.5 percent most cost-effective interventions, youād save about 1,275 years of life. +
++Quite possibly! These are necessarily rough numbers and you shouldnāt take them too literally. You might merely save hundreds of years of life. But the magnitudes here strongly suggest that you should be careful about choosing where to donate, because the difference between the best and the merely okay is huge. +
++Thereās a reason the philosopher Toby Ord, who originated the ā10 percent of income to effective charitiesā pledge idea, has argued that cost-effectiveness is a moral imperative, on par with the moral imperative to give money at all. +
++Good question. The short answer is the US is a rich country, which means everything tends to cost more than it does abroad ā including the cost of helping people in need. The US still has extreme poverty, in the global, living-on-$2-a-day standard, but itās comparatively rare and hard to target effectively. The poorest Americans also have access to health care and education systems that, while obviously inferior compared to those enjoyed by rich Americans, are still superior to those of very poor countries. +
++To be blunt: People in the US simply are not dying for want of a $1.50 anti-malaria pill. (For one thing, the US managed to essentially eradicate malaria transmission from within its borders.) That means it is much, much more cost-effective to help people abroad. +
++Hereās one example. Years ago, GiveWell actually looked into a number of US charities, like the Nurse-Family Partnership program for infants, the KIPP chain of charter schools, and the HOPE job-training program. It found that all were highly effective but were also far more cost-intensive than the best foreign charities. KIPP and the Nurse-Family Partnership cost more than $9,000 per child served, while a program like the Malaria Consortiumās prevention efforts costs around $4,500 per life saved. +
++Thereās been less work on evaluating US charities in recent years than would be ideal, and Iād love to hear about charities that can save lives here very cost-effectively. But right now, the evidence suggests to me that itās much more expensive to save lives in the US than abroad. +
++Thatās a commendable impulse! I get it, really, and if the most I can convince you to do here is give 10 percent of your income to fight poverty in the US, then you should do that and Iāll take the win. +
++But I would also ask you to consider the idea that people in other, much poorer countries have equal moral weight to those who live in your country. Their lives matter just as much. And if you can help, say, 100 of them for the cost of helping one American, and you choose to do the latter, youāre making an implicit choice to value Americans much more than non-Americans. I think there might be valid reasons to make that choice ā but itās not one I want to make, so thatās not how I donate. +
++Indeed they do. I think the best critique of GiveWellās list ā well, less a critique than an argument not to use it exclusively ā is that you can do even more good, even more efficiently if you try to help animals, especially farm animals bred and raised in extreme suffering just so they can be slaughtered. There are billions of them, and very little is spent trying to help them. If you want to help them, Animal Charity Evaluators has some good suggestions of where to give. Iām partial to the Humane League, which pressures corporations to improve their treatment of farmed animals. +
++It does because it is. Todd and Ord were among the founders of effective altruism, and generally the community and people in it have developed a lot of the ideas you see above, from the focus on cost-effectiveness to the āgive 10 percentā idea to taking animals seriously. +
++A bunch of EAs definitely did a bunch of crimes very recently. Sam Bankman-Fried and several of his colleagues at FTX and Alameda Research identified as EAs and stated that they were only becoming billionaires to donate the proceeds to effective charities. Of course, they turned out to be stealing lots of money in the process and Bankman-Fried has since been convicted in federal court. (Disclosure: In 2022, Bankman-Friedās philanthropic family foundation, Building a Stronger Future, awarded Voxās Future Perfect a grant for a 2023 reporting project. That project is now on pause.) +
++I donāt think we know, but there are some theories. One theory is that Bankman-Fried took the idea that you should make as much money as possible and donate it as efficiently as possible, and ran waaaaaay too far with it, to the point where committing outright fraud to make money to donate made sense to him, on the apparent grounds that the potential good that could be done with it was worth the risk to himself and many others. Other theories hold that he was just lying the whole time, never cared about doing the right thing, and used EA as a cover for his own greed. Either way, it reflects very badly on EA. +
++Because theyāre good ideas and theyāre in danger of being totally discredited because of some effective altruists who didnāt even take the ādonate a lot of your income to normal charities that save livesā part of the philosophy seriously. Look at SBF: He distributed a bunch of money to causes he valued, but they were explicitly not causes involving giving people lifesaving medication right now. They were more speculative ālongtermistā causes ā things like AI safety and preventing global catastrophic risks. Whatever you think of that behavior, itās precisely not what Iām asking you to do right now. +
++Because you have the opportunity to save lives, right now, and you should take it. +
++I donāt think youāre āobligated.ā I just think itās a good thing to do and that you should consider it. If everyone did it, we could end global poverty and then some. And I donāt even think itās purely an altruistic good thing. I think itāll be good for you as a person, too. +
++Thatās honestly a big part of why I do it. +
++Sure. Look, I think itās important to do good for other people, in and of itself. Thatās a major motivator, definitely. +
++But ā¦ you ever wonder if your life has meaning? If it makes any kind of difference to the world? Personally, I want to live a life that means something, that leaves things ever so slightly better than I found them. I want to be pursuing goals that arenāt just material. I donāt want to mark the progression of my life solely through raises and promotions, or fall victim to the subtle pressures that push me to spend more and more of my money on gadgets and furniture that make me progressively less happy. +
++Iām talking about a problem that, for me, giving 10 percent of my income away helps solve. One, it helps establish a baseline meaning or impact from my work ā if nothing else,I know that the money I make through my job contributes to saving peopleās lives. That has to count for something. Thatās a source of real meaning and pride. +
++Two, it provides a powerful counterforce to the treadmill that comes as you age and make more money, a treadmill that pushes you to spend lots of it to keep up with your peers or feel like youāre living better. There are definitely times when I feel like Iām not taking as nice a vacation as my friends are, or where I feel kinda cheap for having mostly Wayfair furniture while my friends have a nice, solid wood dining table. Sometimes I blame the donations for these feelings. +
++But mostly I am thankful for them. The idea that, after you reach a certain level of baseline comfort, additional consumer spending is going to make you dramatically happier is a seductive lie. And one of the few weapons I have against it is the knowledge that I face a very real choice between, say, getting one of those amazing lie-flat business-class airplane seats for my next vacation and saving a human beingās life. That lets me resist the former, and live a life that feels just a tiny bit more meaningful. +
++The group Giving What We Can runs a pledge, which I and thousands of others have signed, for people who commit to donating 10 percent of their income to highly effective charities. You can sign if you want. But the main thing to do is just give. +
+Mondayās extension is good news for anyone concerned about the humanitarian situation, but the bigger questions about the future of the war remain. +
++Israel and Hamas agreed Monday to extend a temporary ceasefire under which dozens of Israeli hostages and Palestinian prisoners have been released from captivity. +
++The deal will continue the initial four-day humanitarian pause in fighting through this coming Thursday morning, with the potential for further extensions. The Qatar-mediated agreement is the longest break in hostilities since Hamas attacked Israel on October 7, killing over 1,200 people, and the Israel Defense Forces launched an air and ground assault that has devastated large parts of northern Gaza and killed more than 13,000 Palestinians, according to Gazaās health ministry. The pause has allowed Palestinian civilians to safely access humanitarian goods like food, water, medical supplies, and other basic necessities amid the critical lack caused by the war. +
++Mondayās extension, then, is good news for anyone concerned about the humanitarian conditions and plight of prisoners and hostages. But the bigger questions about the warās path and the future of Gaza remain as unclear as they were when this pause began. +
++One Israeli American citizen, a 4-year-old girl held hostage by Hamas in Gaza since October 7, was released into Israel Sunday as part of the 50 Israeli hostages released since Friday. In return, 150 Palestinian prisoners previously in Israeli jails ā minors and women ā have been released from detention back to their families. As Voxās Abdallah Fayyad explained, Israel holds āthousands of Palestinians, including hundreds of children ā¦ on murky legal grounds.ā +
++Hamas and Palestine Islamic Jihad are still holding well over 100 hostages in Gaza. Most are Israeli or dual citizens, but a number of other nationalities are included in that group, including laborers from countries like Thailand and the Philippines. More than a dozen of those foreigners were released over the weekend. Over the next two days, both sides will release more hostages and prisoners; while no announcements about the extension specified how many on either side, an Egyptian official indicated Monday that Hamas might release 20 hostages while Israel frees 60 prisoners. +
++At this pace of exchange, the ceasefire could continue for days, given the number of hostages still in Gaza. But there is no agreed-upon framework for a long-term deal, and Israeli Prime Minister Benjamin Netanyahu has insisted that the war will go on after the current ceasefire concludes. While the prisoner exchange could strengthen Hamasās political position, further complicating Israelās goal to eradicate the group, Israel appears undeterred. +
++For weeks, news outlets had been reporting about an impending ceasefire and prisoner exchange, but Qatari and US politicians began speaking openly about such a deal and their role in it only last week as an agreement finally appeared near. (Because Israel and Hamas donāt have direct diplomatic channels, Qatar and Egypt, which maintain communication channels with Hamas, were pivotal in securing the ceasefire and exchange.) +
++According to the Associated Press, discussions about a prisoner and hostage exchange emerged as soon as October 12, with the first proposal suggesting all women and children held in Gaza be released in exchange for freeing all Palestinian women held in Israeli prison. That proposal morphed into the current deal over weeks of negotiations brokered primarily by Qatar. +
++Israelās parliament, the Knesset, voted in favor of the deal last Wednesday, with only the ultranationalist, far-right religious party of National Security Minister Itamar Ben Gvir voting against the proposal, according to the Times of Israel. +
++Though there will still be about 150 hostages in Gaza after this extension, that doesnāt mean Hamas can use them to prolong the ceasefire indefinitely; it can only continue another five days following the first extension. Hamas has also only agreed to release civilians; although the militant group that controls Gaza has taken some Israeli soldiers hostage, guaranteeing their release will require further negotiations, Raphael Cohen, director of the Rand Corporationās Strategy and Doctrine Program, Rand Project Air Force, told Vox. āWhen the Israelis want to get the soldiers back, that will presumably be on different terms. Itās one thing if youāre trading Israeli civilians for a handful of, primarily, women and minors,ā some of whom are alleged to have committed serious crimes, Cohen said. For Hamas to release the soldiers, they may ask for āpeople who Israel believes have actually committed murder and who are more senior Hamas operatives ā thatās a very different political calculus.ā +
++Though the ceasefire and prisoner exchange has gone through with minimal interruption, there was an hours-long delay in Saturdayās exchange when Hamas threatened to call off the deal, saying that Israel had not abided by its part of the agreement. However, the planned exchange went ahead, and as of Monday, all parties had agreed to a continuation of the pause. +
++Qatar has become a major player in global diplomacy and has been an important part of the current negotiations, in part because itās one of two nations that maintains a direct relationship with Hamas. āIt wants to be influential, diplomatically, and it does understand that, obviously, itās not a regional superpower that can dictate things,ā Bessma Momani, a political science professor at the University of Waterloo, told Voxās Jen Kirby. That puts Qatar into a challenging balancing act: +
++++Yet maintaining these delicate ties ā and working those connections ā is a very good way for Qatar to advance its interests, and its security. That approach comes with some risks, but, at least right now, they donāt outweigh the upsides for Qatar. +
+
+Hamas has, in the past, taken hostages as a negotiating tool to get Palestinian prisoners released from detention in Israel, and it has historically been effective ā often asymmetrically so, as in the case of Gilad Shalit, an Israeli soldier who, after being held by Hamas for five years, was traded in 2011 for more than 1,000 Palestinian detainees. +
++The present exchange, though nowhere near that scale, still notches a political win for Hamas. +
++āIt shows that not only is Hamas defying this notion that theyāre going to be destroyed,ā Khaled Elgindy, director of the Middle East Instituteās program on Palestine and Palestinian-Israeli affairs, told Vox. āIsrael is still talking about eradicating Hamas, but theyāre forcing Israel to negotiate with them and to release Palestinian prisoners, even in relatively small numbers.ā +
++As Fayyad wrote, Israeli jails hold thousands of Palestinian prisoners, many of whom are held under administrative detention ā meaning indefinitely and without being charged, for reasons as minor as a social media post or nonviolent protest ā in the name of national security. Those who do get a trial are tried in military courts, where the conviction rate is around 99 percent: +
++++Israel maintains that it detains people because of legitimate security concerns, such as potential participation in violent attacks. But while there is a thin veneer of due process ā¦ āEvidence has shown that [administrative detention] is a pretext to persecute and deprive people of their fundamental rights and freedoms because they challenge the Israeli military occupation,ā said [Elizabeth Rghebi, the Middle East and North Africa advocacy director at Amnesty International USA.] +
+
+Many Palestinians āhave had loved ones who have been arrested, detained, tortured, [or had other] experiences in Israeli prisons,ā Elgindy said. āThe fact that Hamas can deliver that in the midst of the most ferocious bombing campaigns we have ever seen in the Gaza Strip is pretty remarkable.ā +
++The ceasefire will also allow Hamas to rearm, to a degree, although substantial regrouping and rearmament would take longer than the brief period allowed under the ceasefire deal, Cohen said. Israelās defense minister Yoav Gallant promised that the pause in hostilities would be just that, āthen we will continue operating with full military power,ā Reuters reported Friday. +
++āI canāt see the truce lasting more than a week,ā Miri Eisin, managing director of the International Institute for Counter-Terrorism, told the Guardian. āThe IDF wants to dismantle Hamasās terror capability and military capability, and the only way to do that is through a systematic and careful ground operation.ā However, the Biden administration signaled Monday that it hoped for a prolonged pause to release as many hostages as possible. +
++What Hamas is betting could change the dynamics of the conflict is that the longer the pause, the āmore international pressure there will be to make this truce permanent,ā Cohen told Vox. āI think it affects more the political calculus rather than the military calculus.ā +
++The pause comes amid growing congressional calls for conditions on military aid to Israel, a concept President Joe Bidenās national security adviser Jake Sullivan didnāt explicitly dismiss during an interview on Sundayās Meet the Press. +
++Despite that, there is no appetite within Israel to negotiate for a permanent ceasefire right now, Cohen said. +
++āAt the end of the day, none of the structural dynamics here have actually changed ā Hamas has been rooted out of more than half of the Gaza Strip, optimistically. Itās still in control of the southern half; many of the Hamas senior leaders ā¦ are still at large, which means that stopping now functionally just means that youāve bought yourself a couple of years of peace, and youāre going to be in the same place again just in a matter of a couple of years.ā +
BAN vs NZ first Test | Phillips takes 4 wickets after Mahmudul Hasanās good start - Phillipsā haul helped the visitors gain an edge after Bangladesh won the toss and opted to bat first on a pitch ideal for batting.
When Kohliās wicket fell, stadium felt quiet like library: Pat Cummins - Workload management might be in vogue in world cricket for past few years but Cummins believes that words like ārestā and ārotationā are loosely thrown around
SC sets aside stay imposed by Punjab and Haryana HC on WFI elections - A bench of justices Abhay S Oka and Pankaj Mithal said it failed to understand how the entire process of the election could have been set at naught by high court.
Morning Digest | Hopes pinned on rat miners to rescue workers trapped in Uttarkashi tunnel; Israel-Hamas truce in Gaza extended by two days, and more - Here is a select list of stories to start the day
Honda brings in Marini to replace Marquez in MotoGP -
Sonia Gandhi appeals to Telangana voters to bring change in the State - In her emotional appeal, former Congress chief thanks the people for honouring her as āSonia ammaā, says she will always be dedicated to them
IIT Madras sets up integrated centre for career guidance - Unified platform will assist students in placement, internship and career development activities
Tiger census under way in Mudumalai Tiger Reserve -
Mangaluru Police arrest two youths in āmoral policingā case - This is the 12th āmoral policingā incident reported in Dakshina Kannada and Udupi districts during 2023
Vigilance stepped up in Mandya and Mysuru following police investigation on female foeticide racket - Drive to ascertain bonafides of medical practitioners and weed out quacks
Ukraine spy chiefās wife poisoned, local media report - Gen Kyrylo Budanovās wife, Marianna, is now in hospital, Ukraineās news websites say quoting sources.
CrĆ©pol murder: French pledge to tackle ultra-right after teen killing sparks protests - The interior minister wants to ban small extremist groups after a boyās stabbing triggered riots.
Niger coup leaders repeal law against migrant smuggling - The legislation allowed police to take action against smugglers taking migrants to Europe.
Samuel Paty: Six French teenagers on trial over teacherās murder - The suspects are accused of inciting the murder and pointing out the teacher to the killer.
Slovenia Covid: Thousands to get lockdown fine refunds - One man fined ā¬400 (Ā£350) for eating a burek pasty outdoors in 2020 will get his money back.
Google Play keeps banning the same web browser due to vague DMCA notices - Downloader app suspended by DMCA notice that didnāt list any copyrighted works. - link
āMysteryā pneumonia in China is mix of common respiratory germs, WHO says - Reports caused alarm, but experts say it looks like a post-COVID germ comeback. - link
New āStable Video Diffusionā AI model can animate any still image - Given GPU and patience, SVD can turn any image into a 2-second video clip. - link
DOS_deck offers free, all-timer DOS games in a browser, with controller support - Playing Warcraft in a browser, using a controller, somehow feelsā¦ okay? - link
Amazonās $195 thin clients are repurposed Fire TV Cubes - Amazon Workspaces Thin Client is a Fire TV Cube with different software. - link
Son: āDaddy, I fell in love and want to date this awesome girl.ā -
++Son: āDaddy, I fell in love and want to date this awesome girl.ā +
++Father: āThatās great, son! Who is she?ā +
++Son: āItās Sandra, the neighborās daughter.ā +
++Father: āOhhh, I wish you hadnāt said that. I have to tell you something, son, but you must promise not to tell your mother. Sandra is actually your sister.ā +
++The boy is naturally bummed out, but a couple of months later: +
++Son: āDaddy, I fell in love again and she is even hotter!ā +
++Father: āThatās great, son! Who is she?ā +
++Son: āItās Angela, the other neighborās daughter.ā +
++Father: āOhhh, I wish you hadnāt said that. Angela is also your sister.ā +
++This went on a few more times, and finally the son was so mad, he went straight to his mother crying. +
++Son: āMom, I am so mad at dad! I fell in love with six girls and I canāt date any of them because dad is their father!ā +
++The mother hugs him affectionately and says, āYou can date whoever you want. He isnāt your father!ā +
+ submitted by /u/Dry_Career_2304
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Two older women were outside their nursing home, having a smoke, when it started to rain. One of the ladies pulled out a condom, cut off the end, put it over her cigarette, and continued smoking. -
++. First Lady:Whats that? Second Lady: A condom. This way my cigarette doesnt get wet. First Lady: Where did you get it? Second Lady : You can get them at any drugstore. The next day, Lady 1 hobbles herself into the local drugstore and announces to the pharmacist that she wants a box of condoms. The guy, obviously embarrassed, looks at her strangely (she is, after all, over 80 years old), but very delicately asks what brand she prefers. Doesnāt matter son, as long as it fits a Camel. +
+ submitted by /u/YZXFILE
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If you HAD to get rid of one race, which one would you get axe? -
++Personally for me it would be the 200m. It lacks the raw sprinting ability needed for the 100m, and the stamina needed for the 400m. +
+ submitted by /u/Indica_Joe
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You donāt wanna mess with me -
++A guy walks into a fancy club and right past the bouncer. When the bouncer tries to stop him, the guy says ālet me through, Iām fucking rich.ā +
++The bouncer, eager for a tip, lets him through. The guy proceeds right to the VIP section, past the ropes, and sits down at the best table. +
++The bouncer tries to stop him again, but the guy says āI can sit wherever I want, Iām fucking rich.ā Again, the bouncer decides to let the guy sit down, still hoping for a big tip. +
++The guy then walks behind the bar, grabs the most expensive top-shelf bottle, and takes it back to his table. The bouncer, realizing that the owner will fire him for letting a guest grab such an expensive bottle, stops the guy a third time and says āI donāt care how wealthy you are, you canāt have that bottle.ā +
++All the sudden a huge man, dwarfing the bouncer, taps him on the shoulder and tells the bouncer to let the guy keep the bottle. +
++Indignant at the bold statement, the bouncer replies āand who the hell are you?ā +
++āRich.ā +
+ submitted by /u/yvrtrip
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Village Idiot -
++One of the best marksmen in the FBI was passing through a small town. Everywhere he saw evidences of the most amazing shooting. On trees, on walls, and on fences there were numerous bullās-eyes with the bullet hole in dead center. The FBI man asked one of the townsmen if he could meet the person responsible for this wonderful marksmanship. The man turned out to be the village idiot. āThis is the best marksmanship I have ever seen,ā said the FBI man. āHow in the world do you do it?ā āNothing to it,ā said the idiot. āI shoot first and draw the circles afterward.ā +
+ submitted by /u/kickypie
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