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<title>16 October, 2022</title>
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<h1 data-aos="fade-down" id="covid-19-sentry">Covid-19 Sentry</h1>
<h1 data-aos="fade-right" data-aos-anchor-placement="top-bottom" id="contents">Contents</h1>
<ul>
<li><a href="#from-preprints">From Preprints</a></li>
<li><a href="#from-clinical-trials">From Clinical Trials</a></li>
<li><a href="#from-pubmed">From PubMed</a></li>
<li><a href="#from-patent-search">From Patent Search</a></li>
</ul>
<h1 data-aos="fade-right" id="from-preprints">From Preprints</h1>
<ul>
<li><strong>Serology assays used in SARS-CoV-2 seroprevalence surveys worldwide: a systematic review and meta-analysis of assay features, testing algorithms, and performance</strong> -
<div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Background: Many SARS-CoV-2 serological assays were rapidly developed during the COVID-19 pandemic. However, differences in detection mechanism limit the comparability of assay outputs. Methods: As part of the SeroTracker global living systematic review of SARS-CoV-2 seroprevalence studies, we collated serological assays used in serosurveys between January 1, 2020 and November 19, 2021. We mapped performance metrics to the manufacturer, third-party head-to-head, and independent group evaluations, comparing the assay performance data using a mixed-effect beta regression model. Results: Among 1807 serosurveys, 192 distinctive commercial assays and 380 self-developed assays were identified. According to manufacturers, 28.6% of all commercial assays met WHO criteria for emergency use (sensitivity [Sn.] &gt;= 90.0%, specificity [Sp.] &gt;= 97.0%). Third-party and independent evaluations indicated that manufacturers overstated the Sn. of their assays by 5.4% and 2.8%, and Sp. by 6.3% and 1.2%. We found in simulations that inaccurate Sn. and Sp. can substantially bias seroprevalence estimates corrected for assay performance. Conclusions: The Sn. and Sp. of the serological assay are not fixed properties, but varying features depending on testing population. To achieve precise population estimates and to ensure comparability, serosurveys should select assays with strong, independently validated performance and adjust seroprevalence estimates based on assured performance data.
</p>
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.10.13.22280957v1" target="_blank">Serology assays used in SARS-CoV-2 seroprevalence surveys worldwide: a systematic review and meta-analysis of assay features, testing algorithms, and performance</a>
</div></li>
<li><strong>Stability of SARS-CoV-2 spike antigens against mutations</strong> -
<div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Modern health care needs preventive vaccines and therapeutic treatments with stability against pathogen mutations to cope with current and future viral infections. At the beginning of the COVID-19 pandemic, our analytic and predictive tool identified a set of eight short SARS-CoV-2 S-spike protein epitopes that had the potential to persistently avoid mutation. Here a combination of genetic, Systems Biology and protein structure analyses confirm the stability of our identified epitopes against viral mutations. Remarkably, this research spans the whole period of the pandemic, during which 93.9% of the eight peptides remained invariable in the globally predominant 43 circulating variants, including Omicron. Likewise, the selected epitopes are conserved in 97% of all 1,514 known SARS-CoV-2 lineages. Finally, experimental analyses performed with these short peptides showed their specific immunoreactivity. This work opens a new perspective on the design of next-generation vaccines and antibody therapies that will remain reliable against future pathogen mutations.
</p>
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.10.13.22280980v1" target="_blank">Stability of SARS-CoV-2 spike antigens against mutations</a>
</div></li>
<li><strong>The SARS-CoV-2 spike N-terminal domain engages 9-O-acetylated α2-8-linked sialic acids</strong> -
<div>
SARS-CoV-2 viruses engage ACE2 as a functional receptor with their spike protein. The S1 domain of the spike protein contains a C-terminal receptor-binding domain (RBD) and an N-terminal domain (NTD). The NTD of other coronaviruses includes a glycan-binding cleft. However, for the SARS-CoV-2 NTD protein-glycan binding was only observed weakly for sialic acids with highly sensitive methods. Amino acid changes in the NTD of Variants of Concern (VoC) shows antigenic pressure, which can be an indication of NTD-mediated receptor binding. Trimeric NTD proteins of SARS-CoV-2, Alpha, Beta, Delta, and Omicron did not reveal a receptor binding capability. Unexpectedly, the SARS-CoV-2 Beta subvariant strain (501Y.V2-1) NTD binding to Vero E6 cells was sensitive to sialidase pretreatment. Glycan microarray analyses identified a putative 9-O-acetylated sialic acid as a ligand, which was confirmed by catch-and-release ESI-MS, STD-NMR analyses, and a graphene-based electrochemical sensor. The Beta (501Y.V2-1) variant attained an enhanced glycan binding modality in the NTD with specificity towards 9-O-acetylated structures, suggesting a dual-receptor functionality of the SARS-CoV-2 S1 domain, which was quickly selected against. These results indicate that SARS-CoV-2 can probe additional evolutionary space, allowing binding to glycan receptors on the surface of target cells.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2022.09.14.507904v2" target="_blank">The SARS-CoV-2 spike N-terminal domain engages 9-O-acetylated α2-8-linked sialic acids</a>
</div></li>
<li><strong>Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single cell resolution</strong> -
<div>
Synthetic glucocorticoids, such as dexamethasone, have been used as treatment for many immune conditions, such as asthma and more recently severe COVID-19. Single cell data can capture more fine-grained details on transcriptional variability and dynamics to gain a better understanding of the molecular underpinnings of inter-individual variation in drug response. Here, we used single cell RNA-seq to study the dynamics of the transcriptional response to glucocorticoids in activated Peripheral Blood Mononuclear Cells from 96 African American children. We employed novel statistical approaches to calculate a mean-independent measure of gene expression variability and a measure of transcriptional response pseudotime. Using these approaches, we demonstrated that glucocorticoids reverse the effects of immune stimulation on both gene expression mean and variability. Our novel measure of gene expression response dynamics, based on the diagonal linear discriminant analysis, separated individual cells by response status on the basis of their transcriptional profiles and allowed us to identify different dynamic patterns of gene expression along the response pseudotime. We identified genetic variants regulating gene expression mean and variability, including treatment-specific effects, and demonstrated widespread genetic regulation of the transcriptional dynamics of the gene expression response.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.09.30.462672v3" target="_blank">Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single cell resolution</a>
</div></li>
<li><strong>TECHNOLOGY BASED LEARNING MODEL DURING THE COVID-19 PANDEMIC</strong> -
<div>
The Covid-19 pandemic has not been completely handled in almost every country in the world up until the end of 2020, its impact was felt by Indonesia. The major changes that continue to occur in all aspects of human life are also targeting the education system. Changes in the education system in Indonesia have a very significant effect on learning and students, where students experience difficulties in following the learning process, especially students at the elementary level. It can be ascertained that the cause is due to the fact that learning is usually carried out conventionally, dominance is still centralized on the educators, and the models used do not vary much. Within a short time period and without preparation, learning must be adapted to the needs, situations and conditions, so that learning can still be carried out. Distance learning process (Pembelajaran Jarak Jauh) using online modes is expected to bridge the relationship and communication between educators and students so that the learning process does not experience obstacles. To make Distance Education implemented optimally, Distance Education cannot be separated from the utilization of Information Technology. This article aims to examine further how the implementation of Distance Education relies on technology, as well as the use of appropriate learning models for students during the Covid-19 pandemic, using descriptive-analytical literature methods. The results and conclusions in this paper indicate that technology-based learning has an important role in the implementation of learning, especially during the Covid-19 pandemic. The management and implementation of technology-based learning is very dependent on Information Technology, facilitating educators so that the continuity of interaction between educators and students does not face any problems. It is hoped that the competence of educators in managing Distance Education using online modes is expected to be continually developed by utilizing various learning models, so that the learning process can be optimized. Although in its implementation there are still several obstacles related to academic culture, including values, attitudes, knowledge, skills, and readiness of technology-related facilities and infrastructure, education management by utilizing various learning models and supporting technology can be one of the solutions in facing challenges of Distance Education during the current Covid-19 pandemic.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/kwe59/" target="_blank">TECHNOLOGY BASED LEARNING MODEL DURING THE COVID-19 PANDEMIC</a>
</div></li>
<li><strong>Examining the influence of user engagement on tourist virtual reality behavioral response from the human-computer interaction perspective: A PLSSEM-IMP-NN hybrid machine learning approach</strong> -
<div>
Due to the impact of the COVID-19 pandemic, new attraction ways are tended to be adapted by compelling sites to provide tours product and services, such as virtual reality (VR) to visitors. Based on human-computer interaction (HCI) user engagement and domain segmentation innovativeness theory, we develop and test a theoretical framework using a hybrid partial least squares structural equation model (PLSSEM) with Importance Performance Matrix (IMP) and neural network machine learning approach (PLSSEM-IMP-NN) that examines key user engagement drivers of visitors’ attitude toward VR (ATT) and in-person tour intentions (ITI) during COVID-19. According to a sample of visitors’ response, the results demonstrate that a) user engagement including aesthetic appeal, focused attention, perceived usability, and reward experience, raise attitude toward VR; b) product-possessing innovativeness positively moderates the relationships between ATT and ITI; c) information-possessing innovativeness negatively moderates the relationships between ATT and ITI; d) ATT exert the mediating effect between user engagement and ITI. The proposed new PLSSEM-IMP-NN approach has been examined and denotes its efficient and effective in HCI and behavioral response assessment. Other contributions to theories and practical implications are discussed accordingly.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/hp259/" target="_blank">Examining the influence of user engagement on tourist virtual reality behavioral response from the human-computer interaction perspective: A PLSSEM-IMP-NN hybrid machine learning approach</a>
</div></li>
<li><strong>Private sector involvement in social and affordable housing</strong> -
<div>
This research investigates models for engaging private sector investors and developers in financing or delivering social and affordable housing, across different market segments and tenures in Australia and internationally. It also identifies key existing and potential players, and financial, regulatory, or development barriers to wider participation. Prior to the COVID-19 pandemic, around 3,000 social and affordable dwellings were being produced per year, against an estimated annual need of around 36,000 homes. To meet the forecast demand, it is clear ‘hybridity’ of the housing system is essential, whereby social and affordable housing is increasingly financed, developed and managed by a combination of government, community-based and market providers, and cross-sector partnerships; no one sector can address the need alone. This study highlighted that a range of established and emerging affordable housing product types can be supported through collaboration with private not-for-profit and for-profit partners. These strategies include public private partnerships, mixed tenure developments, tax subsidies for affordable supply, home ownership schemes, build to rent and inclusionary planning mechanisms. These depend on different combinations of government subsidy, policy settings, and regulation, and are suitable for delivery across a variety of different development contexts.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/preprints/socarxiv/9h6qj/" target="_blank">Private sector involvement in social and affordable housing</a>
</div></li>
<li><strong>Misleading Beyond Visual Tricks: How People Actually Lie with Charts</strong> -
<div>
Data visualizations can empower an audience to make informed decisions. At the same time, deceptive representations of data can lead to inaccurate interpretations while still providing an illusion of data-driven insights. Existing research on misleading visualizations primarily focuses on examples of charts and techniques previously reported to be deceptive. These approaches do not necessarily describe how charts mislead the general population in practice. We instead present an analysis of data visualizations found in a real-world discourse of a significant global event—Twitter posts with visualizations related to the COVID-19 pandemic. Our work shows that, contrary to conventional wisdom, violations of visualization design guidelines are not the dominant way people mislead with charts. Specifically, they do not disproportionately lead to reasoning errors in posters’ arguments. Through a series of examples, we present common reasoning errors and discuss how even faithfully plotted data visualizations can be used to support misinformation online.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/ky6th/" target="_blank">Misleading Beyond Visual Tricks: How People Actually Lie with Charts</a>
</div></li>
<li><strong>Joko Widodo Views on Women’s Interests Before and During the Pandemic Based on Social-Media</strong> -
<div>
The COVID-19 Pandemic has had many impacts on Indonesian women. As one of the pilot countries for the HeForShe project campaigned by UN Women, it is interesting to analyze how the President of Indonesia responds to this phenomenon. Many studies focus on the impact of the COVID-19 Pandemic on women. But, there is a lack of research on how the government responds to women’s interests during the Pandemic compared to the situation before the Pandemic. Using a qualitative approach, this study analyses how the President of Indonesia views women’s interests before and during the COVID-19 Pandemic. Two official social-media of the President of Republic Indonesia Joko Widodo: The Official Twitter Account of the President of Indonesia @jokowi and The Official Facebook Account of The President of Indonesia @Jokowi · Minat are used as the primary data sources. The findings indicate that before the COVID-19 Pandemic, President Joko Widodo gave significant attention to strategic women’s interests such as subordination and gender equality. But the situation changed during the Pandemic. The President views the fulfillment of daily needs such as food and health as more urgent for women in the COVID-19 Pandemic than strategic interests. This study highlights that in a crisis, the focus of the government policy is safe for the people first (women and men) to fulfill their basic needs. The gender equality agenda is becoming marginalized.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/p5kfu/" target="_blank">Joko Widodo Views on Women’s Interests Before and During the Pandemic Based on Social-Media</a>
</div></li>
<li><strong>The Effect of Chairobic Dance Program on Cardiorespiratory Endurance in Faculty of Education Staff, Thaksin University</strong> -
<div>
The COVID-19 pandemic has impacted all aspects of daily life, especially exercise, where restrictions on location, time, and work can make exercise even more difficult. Hence, this study aims to create a Chairobic dance program dancing with a chair that uses few spaces, able to sit and dance in your chair. It was developed from the aerobics dance. In addition, to compare the effect of the Chairobic dance program on Cardiorespiratory endurance before and after training. The target group is 24 staff of the Faculty of Education at Thaksin University. The participants were trained through a Chairobic dance program created by the researcher for eight weeks (3 days/week, i.e., Monday, Wednesday, and Friday). They have to practice 45 minutes a day after work. The Cardiorespiratory endurance was tested using a 3-minute knee-up and down test and compared before and after eight weeks of training by the Pair t-test statistics. The results showed that in the Chairobic dance program created by the researcher, there is an IOC (Index of Item-Objective Congruence) in the range of 0.6 -1.00, which is acceptable and usable. In addition, the target group had better Cardiorespiratory endurance than before training. Therefore, It will be helpful for anyone interested in an alternative to exercise. This is because it takes up less space, is convenient to exercise, fun, and can develop Cardiorespiratory endurance.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/5g8wu/" target="_blank">The Effect of Chairobic Dance Program on Cardiorespiratory Endurance in Faculty of Education Staff, Thaksin University</a>
</div></li>
<li><strong>Did the pandemic increase social media-induced appearance pressures? A longitudinal analysis of social media caused appearance-related pressures before and during the Covid-19 pandemic</strong> -
<div>
Has the use of social media intensified and increased appearance-related pressures during the Covid-19 pandemic? A growing body of research has suggested that body image concerns and disordered eating have increased during the Covid-19 pandemic. One of the potential pathways includes an increase in social media use. However, examinations of this pathway have been limited because of the lack of longitudinal data. Drawing on a four-wave population-based survey, we demonstrate that social media-based appearance pressures did not increase at the beginning of the pandemic, but rather at the later stage, and among women only. However, the changes in social media use do not explain this subtle increase. These findings suggest that other pathways than intensified use of social media might be more useful in explaining increased appearance-related pressures during the Covid-19 pandemic.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/preprints/socarxiv/9q7xj/" target="_blank">Did the pandemic increase social media-induced appearance pressures? A longitudinal analysis of social media caused appearance-related pressures before and during the Covid-19 pandemic</a>
</div></li>
<li><strong>Coping with Covid 19 lockdown: Optimism and Intolerance of Uncertainty in India</strong> -
<div>
Background: Kerala state in India has been hailed as an exceptional model in containing the Covid 19 pandemic within a low resource setting Insights from such a setting are valuable for mental health research during an epidemic situation, especially for resource poor countries. Aims:The study examined the relationship between optimism intolerance of uncertainty (IU), and socio- demographic factors among participants from Kerala, India. Methods: An observational design was used and data was collected using online survey. Snowball sampling method was employed. Sample consisted of 121 adults belonging to Kerala. Standardised tools and customised questionnaire were used for data collection. Descriptive and inferential statistics were employed. Results: A strong relationship existed between inhibitory anxiety and optimism. Socio-demographic factors did not determine either intolerance of uncertainty or optimism. The unprecedented uncertainty brought about by the pandemic needs further exploration. Conclusions: The present pandemic has presented an unprecedented situation regarding well being of individuals. Further studies on anxiety and related issues, and protective factors during situations of uncertainty are needed for policy and practice related to community level disaster preparedness.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/bzfp7/" target="_blank">Coping with Covid 19 lockdown: Optimism and Intolerance of Uncertainty in India</a>
</div></li>
<li><strong>Broad SARS-CoV-2 Neutralization by Monoclonal and Bispecific Antibodies Derived from a Gamma-infected Individual</strong> -
<div>
The worldwide pandemic caused by SARS-CoV-2 has remained a human medical threat due to the continued evolution of multiple variants that acquire resistance to vaccines and prior infection. Therefore, it is imperative to discover monoclonal antibodies (mAbs) that neutralize a broad range of SARS-CoV-2 variants for therapeutic and prophylactic use. A stabilized autologous SARS-CoV-2 spike glycoprotein was used to enrich antigen-specific B cells from an individual with a primary Gamma variant infection. Five mAbs selected from those B cells showed considerable neutralizing potency against multiple variants of concern, with COVA309-35 being the most potent against the autologous virus, as well as against Omicron BA.1 and BA.2. When combining the COVA309 mAbs as cocktails or bispecific antibody formats, the breadth and potency was significantly improved against all tested variants. In addition, the mechanism of cross-neutralization of the COVA309 mAbs was elucidated by structural analysis. Altogether these data indicate that a Gamma-infected individual can develop broadly neutralizing antibodies.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2022.10.14.512216v1" target="_blank">Broad SARS-CoV-2 Neutralization by Monoclonal and Bispecific Antibodies Derived from a Gamma-infected Individual</a>
</div></li>
<li><strong>Computational Prediction of Binding Affinities of Human Angiotensin Converting Enzyme-2 with SARS-CoV-2 Spike Protein Variants: Omicron Variants and Potentially Deleterious Mutations</strong> -
<div>
The Omicron variant (BA.1) and its sub-variants of the SARS-CoV-2 virus which causes the COVID-19 disease continues to spread across the United States and the World at large. As new sub-variants of SARS-CoV-2 continue to proliferate, a reliable computational method of quickly determining the potential infectivity of these new variants is needed to assess their potential threat. In the present study, we have tested and validated an efficient computational protocol, which includes an efficient energy minimization and subsequent molecular mechanics/Poisson Boltzmann surface area (MM-PBSA) calculation of the binding free energy between the SARS-CoV-2 spike protein and human angiotensin converting enzyme-2 (ACE2), to predict the binding affinities of these spike/ACE2 complexes based upon the calculated binding free energies and a previously calibrated linear correlation relationship. The predicted binding affinities are in good agreement with available experimental data including those for Omicron variants, suggesting that the predictions based on this protocol should be reasonable. Further, we have investigated several hundred potential mutations of both the wildtype and Omicron variants of the SARS-CoV-2 spike protein. Based on the predicted binding affinity data, we have identified several mutations that have the potential to vastly increase the binding affinity of the spike protein to ACE2 within both the wildtype and Omicron variants.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2022.10.14.512203v1" target="_blank">Computational Prediction of Binding Affinities of Human Angiotensin Converting Enzyme-2 with SARS-CoV-2 Spike Protein Variants: Omicron Variants and Potentially Deleterious Mutations</a>
</div></li>
<li><strong>TCID50 Measurements of anti-viral efficacy on metal printed masks and plastic surfaces</strong> -
<div>
The SARS-CoV-2 pandemic has created a need for effective personal protective equipment (PPE) to prevent viral spread. PPE like face masks contain the spread of virus-filled droplets and thus reduce infection rates, has been a critical tool in stopping the spread of SARS-CoV-2. PET plastic barriers have also been used in public settings to reduce face to face viral transmission. However, in some cases, they have provided additional contact with the virus due to contamination. In order study, we evaluated the effectiveness of face masks and PET plastics coated in different metals in reducing viral load. We compared PPE printed with silver, copper, or zinc for their ability to inactivate live human coronavirus HCoV 229E. Our results show that silver and copper have significant anti-viral efficacy when printed on nonwoven fabric compared to the controls. The metal-printed PET showed around 70% anti-viral efficacy with any formulations, with copper performing the best. This work builds more data to support the development of metal printed materials for enhanced protection against coronaviruses.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2022.10.13.512105v1" target="_blank">TCID50 Measurements of anti-viral efficacy on metal printed masks and plastic surfaces</a>
</div></li>
</ul>
<h1 data-aos="fade-right" id="from-clinical-trials">From Clinical Trials</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Study to Learn About a Repeat 5-Day Treatment With the Study Medicines (Called Nirmatrelvir/Ritonavir) in People 12 Years Old or Older With Return of COVID-19 Symptoms and SARS-CoV-2 Positivity After Finishing Treatment With Nirmatrelvir/Ritonavir</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Drug: nirmatrelvir;   Drug: ritonavir;   Drug: placebo for nirmatrelvir<br/><b>Sponsor</b>:   Pfizer<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Recombinant Omicron-Delta COVID-19 Vaccine (CHO Cell)</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Biological: Recombinant Omicron-Delta COVID-19 Vaccine (CHO Cell);   Biological: Inactivated COVID-19 vaccine (Vero Cell)<br/><b>Sponsors</b>:   Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.;   First Affiliated Hospital Bengbu Medical College<br/><b>Active, not recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Phase III Study to Evaluate Immunogenicity and Safety of COVID-19 Vaccine EuCorVac-19 in Healthy Adults</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Biological: EuCorVac-19;   Biological: ChAdOx1<br/><b>Sponsor</b>:   EuBiologics Co.,Ltd<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Study Evaluating Diltiazem in Combination With Standard Treatment in the Management of Patients Hospitalized With COVID-19 Pneumonia</strong> - <b>Condition</b>:   COVID-19<br/><b>Intervention</b>:   Drug: DILTIAZEM TEVA 60 mg or placebo<br/><b>Sponsors</b>:   Hospices Civils de Lyon;   Signia Therapeutics<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>VAX-MOM COVID-19: Increasing Maternal COVID-19 Vaccination</strong> - <b>Conditions</b>:   Immunization; Infection;   Pregnancy Related;   COVID-19<br/><b>Interventions</b>:   Behavioral: VAX-MOM COVID-19 Intervention;   Other: Standard of Care<br/><b>Sponsors</b>:   University of Rochester;   Centers for Disease Control and Prevention;   University of California, Los Angeles<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>COVID-19 Simulation Education on Nursing Students</strong> - <b>Conditions</b>:   COVID-19 Pandemic;   Simulation of Physical Illness<br/><b>Interventions</b>:   Behavioral: Simulation training;   Other: Control Group<br/><b>Sponsor</b>:   Mehmet Akif Ersoy University<br/><b>Completed</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>COVID-19 Booster Dose Reminder/Recall for Adolescents</strong> - <b>Condition</b>:   COVID-19 Vaccines<br/><b>Intervention</b>:   Behavioral: Reminder/Recall Sent Via Preferred Method of Communication<br/><b>Sponsor</b>:   Marshfield Clinic Research Foundation<br/><b>Active, not recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Safety and Immunogenicity of AdCLD-CoV19-1 OMI as a Booster: A SARS-CoV-2 (COVID-19) Preventive Vaccine</strong> - <b>Conditions</b>:   COVID-19;   Vaccines<br/><b>Interventions</b>:   Biological: AdCLD-CoV19-1 OMI (Part A);   Biological: AdCLD-CoV19-1 OMI (Part B);   Other: Placebo (Part B)<br/><b>Sponsor</b>:   Cellid Co., Ltd.<br/><b>Active, not recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Effect of Different Masks Used by Pregnant Women on Vital Signs and Non Stress Test During The COVID-19</strong> - <b>Conditions</b>:   Covid-19;   Pregnant;   Fetus;   Mask<br/><b>Intervention</b>:   Behavioral: Single surgical mask group, Double surgical mask group, N95 mask group<br/><b>Sponsor</b>:   Bozok University<br/><b>Completed</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Personalized Computerized Training Program for Cognitive Dysfunction After COVID-19</strong> - <b>Conditions</b>:   Post-Acute COVID-19;   Long COVID<br/><b>Intervention</b>:   Device: CogniFit’s CCT Post COVID-19<br/><b>Sponsor</b>:   Universidad Antonio de Nebrija<br/><b>Completed</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Understanding the Impact of Death Conditions Linked to the COVID-19 Crisis on the Grieving Process in Bereaved Families</strong> - <b>Condition</b>:   Psychological Disorder<br/><b>Intervention</b>:   Other: Qualitative research interview<br/><b>Sponsor</b>:   Assistance Publique - Hôpitaux de Paris<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) in People With Post Covid-19 Condition.</strong> - <b>Conditions</b>:   Emotional Disorder;   Post COVID-19 Condition;   Anxiety Disorders;   Depressive Disorder<br/><b>Intervention</b>:   Behavioral: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders<br/><b>Sponsor</b>:   Instituto de Investigación Sanitaria Aragón<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Sequential Enhanced Safety Study of a Novel Coronavirus Messenger RNA (mRNA) Vaccine in Adults Aged 18 Years and Older.</strong> - <b>Condition</b>:   Corona Virus Disease 2019(COVID-19)<br/><b>Intervention</b>:   Biological: 0.3ml of mRNA vaccine<br/><b>Sponsor</b>:   Yu Qin<br/><b>Enrolling by invitation</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Impact of Teeth Brushing in Ventilated COVID-19 Patients.</strong> - <b>Conditions</b>:   Microbial Colonization;   COVID-19 Respiratory Infection;   Dysbiosis;   VAP - Ventilator Associated Pneumonia;   HAI<br/><b>Intervention</b>:   Procedure: Oral Procedure<br/><b>Sponsor</b>:   University Hospital in Krakow<br/><b>Completed</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Physiology of Long COVID and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity</strong> - <b>Condition</b>:   Post-acute Sequelae of SARS-CoV-2 Infection<br/><b>Intervention</b>:   Behavioral: Exercise<br/><b>Sponsor</b>:   University of Colorado, Denver<br/><b>Not yet recruiting</b></p></li>
</ul>
<h1 data-aos="fade-right" id="from-pubmed">From PubMed</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Developing PI3K Inhibitors for Respiratory Diseases</strong> - A number of different experimental models using both non-selective and selective PI3K inhibitors have shown that many pathogenic steps of respiratory disorders, such as bronchial asthma, Chronic Obstructive Pulmonary Disease (COPD), Idiopathic Pulmonary Fibrosis (IPF), Acute Respiratory Distress Syndrome (ARDS) and Lung Cancer (LC) are, at least in part, regulated by the PI3K signaling pathway, suggesting that the inhibition of PI3K could represent an ideal therapeutic target for the treatment…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Glucocorticoids and COVID-19</strong> - Coronavirus Disease 19 (COVID-19) is associated with high morbidity and mortality rates globally, representing the greatest health and economic challenge today. Several drugs are currently approved for the treatment of COVID-19. Among these, glucocorticoids (GCs) have received particular attention due to their anti-inflammatory and immunosuppressive effects. In fact, GC are widely used in current clinical practice to treat inflammatory, allergic and autoimmune diseases. Major mechanisms of GC…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Thrombopoietin participates in platelet activation in COVID-19 patients</strong> - BACKGROUND: The pathogenesis of coronavirus disease 2019 (COVID-19) is characterized by enhanced platelet activation and diffuse hemostatic alterations, which may contribute to immunothrombosis/thromboinflammation and subsequent development of target-organ damage. Thrombopoietin (THPO), a growth factor essential to megakariocyte proliferation, is known to prime platelet activation and leukocyte-platelet interaction. In addition, THPO concentrations increase in several critical diseases, such as…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Bioactive compounds of Jingfang Granules against SARS-CoV-2 virus proteases 3CL<sup>pro</sup> and PL<sup>pro</sup></strong> - CONCLUSION: Prim-O-glucosylcimifugin, neohesperidin, and naringin as the major compounds from Jingfang Granules could inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus proteases 3CL^(pro) and PL^(pro). The results are valuable for rational clinical use of Jingfang Granules.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Synergistic action of organophosphates and COVID-19 on inflammation, oxidative stress, and renin-angiotensin system can amplify the risk of cardiovascular maladies</strong> - Organophosphates (OPs) are ubiquitous environmental contaminants, widely used as pesticides in agricultural fields. In addition, they serve as flame-retardants, plasticizers, antifoaming or antiwear agents in lacquers, hydraulic fluids, and floor polishing agents. Therefore, world-wide and massive applications of these compounds have increased the risk of unintentional exposure to non-targets including the human beings. OPs are neurotoxic agents as they inhibit the activity of acetylcholine…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Immune-Related Adverse Events Among COVID-19-Vaccinated Patients With Cancer Receiving Immune Checkpoint Blockade</strong> - CONCLUSIONS: These findings should reassure providers that COVID-19 vaccination during ICI therapy is safe and efficacious.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Computational molecular interaction between SARS-CoV-2 main protease and theaflavin digallate using free energy perturbation and molecular dynamics</strong> - Our objective was to identify the molecule which can inhibit SARS-CoV-2 main protease and can be easily procured. Natural products may provide such molecules and can supplement the current custom chemical synthesis-based drug discovery for this objective. A combination of docking approaches, scoring functions, classical molecular dynamic simulation, binding pose metadynamics, and free energy perturbation calculations have been employed in this study. Theaflavin digallate has been observed in…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Acriflavine and proflavine hemisulfate as potential antivirals by targeting M<sup>pro</sup></strong> - The evolving SARS-CoV-2 epidemic buffets the world, and the concerted efforts are needed to explore effective drugs. M^(pro) is an intriguing antiviral target for interfering with viral RNA replication and transcription. In order to get potential anti-SARS-CoV-2 agents, we established an enzymatic assay using a fluorogenic substrate to screen the inhibitors of M^(pro). Fortunately, Acriflavine (ACF) and Proflavine Hemisulfate (PRF) with the same acridine scaffold were picked out for their good…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Intradermal Testing With COVID-19 mRNA Vaccines Predicts Tolerance</strong> - CONCLUSION: Sensitization to SARS-CoV-2 mRNA vaccines can be detected with intradermal testing. Significantly more individuals were sensitized to mRNA vaccines in the post-vaccination cohort. A two-step 10-90%-vaccination protocol can be safely administered upon negative skin testing.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution</strong> - The genome of SARS-CoV-2 encodes for a helicase called nsp13 that is essential for viral replication and highly conserved across related viruses, making it an attractive antiviral target. Here we use nanopore tweezers, a high-resolution single-molecule technique, to gain detailed insight into how nsp13 turns ATP-hydrolysis into directed motion along nucleic acid strands. We measured nsp13 both as it translocates along single-stranded DNA or unwinds short DNA duplexes. Our data confirm that nsp13…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Prophylactic treatment of <em>Glycyrrhiza glabra</em> mitigates COVID-19 pathology through inhibition of pro-inflammatory cytokines in the hamster model and NETosis</strong> - Severe coronavirus disease (COVID-19) is accompanied by acute respiratory distress syndrome and pulmonary pathology, and is presented mostly with an inflammatory cytokine release, a dysregulated immune response, a skewed neutrophil/lymphocyte ratio, and a hypercoagulable state. Though vaccinations have proved effective in reducing the COVID-19-related mortality, the limitation of the use of vaccine against immunocompromised individuals, those with comorbidity, and emerging variants remains a…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>3’UTR of SARS-CoV-2 spike gene hijack host miR-296 or miR-520h to disturb cell proliferation and cytokine signaling</strong> - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has becoming globally public health threat. Recently studies were focus on SARS-CoV-2 RNA to design vaccine and drugs. It was demonstrated that virus RNA could play as sponge to host noncoding RNAs to regulate cellular processes. Bioinformatic research predicted a series of motif on SARS-CoV-2 genome where are targets of human miRNAs. In this study, we used dual-luciferase reporter assays to validate the interaction between 3’UTR of…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Synthesis and Evaluation of a Silver Nanoparticle/Polyurethane Composite That Exhibits Antiviral Activity against SARS-CoV-2</strong> - In this proof-of-concept study, we aim to produce a polyurethane (PU)-based composite that can reduce the amount of viable SARS-CoV-2 virus in contact with the surface of the polymeric film without further interventions such as manual cleaning. Current protocols for maintaining the hygiene of commonly used touchpoints (door handles, light switches, shop counters) typically rely on repeated washing with antimicrobial products. Since the start of the SARS-CoV-2 pandemic, frequent and costly…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Antibacterial, Antifungal and Antiviral Polymeric Food Packaging in Post-COVID-19 Era</strong> - Consumers are now more concerned about food safety and hygiene following the COVID-19 pandemic. Antimicrobial packaging has attracted increased interest by reducing contamination of food surfaces to deliver quality and safe food while maintaining shelf life. Active packaging materials to reduce contamination or inhibit viral activity in packaged foods and on packaging surfaces are mostly prepared using solvent casting, but very few materials demonstrate antiviral activity on foods of animal…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Mulberrofuran G, a Mulberry Component, Prevents SARS-CoV-2 Infection by Blocking the Interaction between SARS-CoV-2 Spike Protein S1 Receptor-Binding Domain and Human Angiotensin-Converting Enzyme 2 Receptor</strong> - Despite the recent development of RNA replication-targeted COVID-19 drugs by global pharmaceutical companies, their prescription in clinical practice is limited by certain factors, including drug interaction, reproductive toxicity, and drug resistance. COVID-19 drugs with multiple targets for the SARS-CoV-2 life cycle may lead to a successful reduction in drug resistance as well as enhanced therapeutic efficacy, and natural products are a potential source of molecules with therapeutic effects…</p></li>
</ul>
<h1 data-aos="fade-right" id="from-patent-search">From Patent Search</h1>
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<h1 data-aos="fade-down" id="daily-dose">Daily-Dose</h1>
<h1 data-aos="fade-right" data-aos-anchor-placement="top-bottom" id="contents">Contents</h1>
<ul>
<li><a href="#from-new-yorker">From New Yorker</a></li>
<li><a href="#from-vox">From Vox</a></li>
<li><a href="#from-the-hindu-sports">From The Hindu: Sports</a></li>
<li><a href="#from-the-hindu-national-news">From The Hindu: National News</a></li>
<li><a href="#from-bbc-europe">From BBC: Europe</a></li>
<li><a href="#from-ars-technica">From Ars Technica</a></li>
<li><a href="#from-jokes-subreddit">From Jokes Subreddit</a></li>
</ul>
<h1 data-aos="fade-right" id="from-new-yorker">From New Yorker</h1>
<ul>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Donald Trump, January 6th, and the Elusive Search for Accountability</strong> - Susan B. Glasser writes about the final hearing of the House select committee investigating the January 6, 2021, insurrection, and asks whether all of the panel’s work will result in Donald Trump facing any accountability. - <a href="https://www.newyorker.com/news/letter-from-bidens-washington/donald-trump-january-6th-and-the-elusive-search-for-accountability">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Why Is High Inflation Proving So Persistent?</strong> - The final Consumer Price Index before the midterms came in higher than expected, but price rises are likely to moderate in the months ahead. - <a href="https://www.newyorker.com/news/our-columnists/why-is-high-inflation-proving-so-persistent">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>North Carolina’s Overlooked Senate Race</strong> - Democrats have a chance to flip a Republican seat. Meanwhile, the state legislature is fighting to reduce judicial oversight in federal elections. - <a href="https://www.newyorker.com/news/q-and-a/north-carolinas-overlooked-senate-race">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Extreme Economic Pain of Running a Restaurant in the U.K.</strong> - In a country where eating out is seen as more of a luxury than a necessity, it is one of the first expenses that people forgo in hard times. - <a href="https://www.newyorker.com/news/dispatch/the-extreme-economic-pain-of-running-a-restaurant-in-the-uk">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Supreme Court, for Now, Is Playing a Central Role in Discrediting Donald Trump</strong> - But the former President will continue to search relentlessly for friendly judges nationwide between now and 2024. - <a href="https://www.newyorker.com/news/daily-comment/the-supreme-court-for-now-is-playing-a-central-role-in-discrediting-donald-trump">link</a></p></li>
</ul>
<h1 data-aos="fade-right" id="from-vox">From Vox</h1>
<ul>
<li><strong>The skills you should know before moving out on your own</strong> -
<figure>
<img alt="A cartoon of a person looking through blinds into a room filled with tax forms, garbage, and cooking utensils." src="https://cdn.vox-cdn.com/thumbor/oeHeTT9HwYHPmQMHZ8zwAQKXlOA=/600x0:4200x2700/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/71502140/V2_PaigeVickers_VoxFinal_10_12.0.jpg"/>
<figcaption>
Paige Vickers for Vox
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
How to budget, make a phone call, and other important life skills you should know.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="nMXF3E">
When Genevieve Bellaire graduated from law school in 2015 at 26 years old, she had acquired ample knowledge of case law, but didn’t really understand the deal with health insurance, taxes, or how to find an apartment. What were all these forms she was being asked to complete at her new job? How do you set up a 401(k)? “I found that I just really didn’t have the answer,” Bellaire says, “and oftentimes, didn’t even know the question to ask to make smart decisions.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="sRkyin">
Bellaire realized many young people were similarly ill-equipped to deal with the realities of adulthood. According to <a href="https://swnsdigital.com/us/2021/07/eighty-one-percent-of-recent-college-graduates-wish-they-were-taught-more-life-skills-before-graduating/">a 2021 survey</a> of recent US college grads, 81 percent wished they were taught more life skills before they graduated. After years of following a syllabus, there are few instructions for how to get your act together outside the confines of a classroom or your parents’ home, she thought. In 2021, Bellaire launched Realworld, an app designed to answer those same adulting questions for its user base of over 100,000.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="cEAJRZ">
The responsibilities newly independent adults face are vast, and range from hard skills, like budgeting, to soft skills, like relationship deftness. Everyone’s experience on the road to adulthood won’t mirror Bellaire’s exactly — maybe you’ve been working full time since before leaving home; maybe you didn’t pursue higher education; maybe you’re the primary caregiver for your parents, siblings, or children. Regardless of your situation, there are common responsibilities and skills that can be mystifying if you’ve never heard of them before or were never taught. You don’t need to be an expert in all aspects of adulting (and many of these topics are expansive and complicated), but experts say having some baseline knowledge about key subjects will help make the transition into self-reliance a little smoother.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="oXn61B">
These tips are meant as a general framework rather than a purely prescriptive guide, since so much of how you approach finances and relationships depends on your situation — so come up with systems that work for you.
</p>
<h3 id="Z3A5MM">
Budgeting and finances
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="NwBdts">
Realworld users are consistently most concerned about budgeting, Bellaire says. Surveys show Gen Z Americans are <a href="https://www.nerdwallet.com/blog/generation-z-money-survey/">anxious about their finances</a> yet <a href="https://mint.intuit.com/blog/budgeting/spending-knowledge-survey/">don’t know how much they spend in a given month</a>.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="DL1MuO">
Budgeting doesn’t need to be complicated. First, determine how much money you take home every month. This is the amount of money you earn after taxes, social security, health insurance, and retirement are taken from your paycheck. This is easier to calculate if you have a salary or work a set amount of hours each week, and your employer already removes these deductions. If you’re a freelancer or contract employee, <a href="https://www.keepertax.com/self-employment-tax-rate-calculator">set aside</a> <a href="https://www.thebalancemoney.com/how-much-do-i-budget-for-taxes-as-a-freelancer-453676">20 to 30 percent</a> of your earnings for taxes.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="A3P7O3">
Next, tally up your expenses. This includes rent or mortgage, utility bills, student loans, health insurance premiums (if you pay for health insurance independently), food, transportation, car insurance, child care, and any other bills.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="LRcwfw">
From there, you’ll need to figure out how you’re going to allocate your income to cover your expenses and beyond. Bellaire is a proponent of the <a href="https://www.nerdwallet.com/article/finance/nerdwallet-budget-calculator">50/30/20 budget</a>, in which 50 percent of your income goes to needs (housing, food, transportation, child care, utilities), 30 percent goes to wants (streaming subscriptions, dining out, concerts, entertainment), and 20 percent goes to yourself (savings account, retirement account, paying off debt). These breakdowns won’t work for everyone’s circumstances, especially if you financially support other people, but you should have a general idea of how much you’re spending versus bringing in.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="79KRcO">
It’s also worth incorporating some buffer money, says Alyssa Mairanz, founder of the online platform and e-course <a href="https://adultingintherealworld.com/">Adulting In The Real World</a>. “Not every month is going to be the exact same expenses,” she says. “Things come out of the blue.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ajb0fu">
You can track your budget in a spreadsheet, a <a href="https://www.businessinsider.com/personal-finance/best-budgeting-apps">budgeting app</a> or go old-school with a notebook.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="zB2jyF">
If you can, start saving for retirement, Bellaire says. Read through any materials given to you by your employer if you’re enrolling in their 401(k) plan. Mairanz suggests seeking out a <a href="https://www.investopedia.com/articles/personal-finance/050815/what-do-financial-advisers-do.asp">financial adviser</a> who can offer financial advice and can help with retirement planning. (Just be aware of <a href="https://money.usnews.com/financial-advisors/articles/financial-advisor-fees-and-costs">how they get paid</a>: through a fee or commission.)
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="NZmKGr">
Young adults should also know their credit score, Bellaire says. Your <a href="https://www.consumerfinance.gov/ask-cfpb/what-is-a-credit-score-en-315/">credit score</a> measures your trustworthiness as a consumer and the likelihood of you paying back a loan. “We like to call it the GPA of the real world,” Bellaire says. “It’s the most important three-digit number that can have a big impact on your ability to rent an apartment, to buy a house, buy a car, even get a job.” Yes, the calculation for determining a credit score is <a href="https://www.vox.com/the-goods/22736387/how-credit-scores-work-equifax-experian-transunion">discriminatory and arbitrary</a>, but it’s still a figure worth having in your back pocket. You can check <a href="https://www.usa.gov/credit-reports/">your credit report online</a> to keep tabs on your credit score.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="hDnB7q">
Young people may not have credit and will need to build it in order to get a loan or rent an apartment. You can <a href="https://www.bankrate.com/personal-finance/credit/how-to-build-credit/">build credit</a> by <a href="https://www.nerdwallet.com/article/finance/how-to-build-credit">getting a credit card</a>, or becoming an authorized user on your parents’ card, and setting up automatic payments. Sometimes, putting a major expense, like a medical bill, on a credit card is unavoidable, but if you can, try to avoid making major purchases on a credit card. Try to pay back your credit card bills in full if you can; interest will accrue quickly and you don’t want to struggle for years with paying off credit card debt.
</p>
<h3 id="efyweK">
Health insurance
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="rOe9on">
Young people can stay on their parents’ health insurance until they’re 26, but may choose to get their own insurance if their parents are not insured, they prefer to join their company plan, or they purchase their own insurance through <a href="http://HealthCare.gov">HealthCare.gov</a>, the health insurance marketplace. (<a href="https://www.healthcare.gov/quick-guide/dates-and-deadlines/">Open enrollment through the marketplace</a> is November 1, 2022, through January 15, 2023.)
</p>
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If you’re covered under your workplace plan, double check the dates for open enrollment and if you need to reelect coverage each year. If you lost coverage, got married, or had a baby and need to change your coverage during the year, you qualify for a <a href="https://www.healthcare.gov/glossary/special-enrollment-period/">special enrollment period</a> and can make those changes.
</p>
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When you’re shopping for plans or making selections on your company plan, you’re going to need to learn some lingo. “People need to understand deductibles,” Mairanz says. A deductible is what you pay when you see a doctor who is covered by your insurance before your insurance starts to pay. If your <a href="https://www.healthcare.gov/glossary/deductible/#:~:text=The%20amount%20you%20pay%20for,insurance%20plan%20starts%20to%20pay.">deductible</a> is $2,000, you’ll need to pay for $2,000 worth of services by an in-network provider. After you hit your deductible, you’ll pay a copay or coinsurance for covered services and the insurance company will pay the rest. Most health insurance plans cover <a href="https://www.healthcare.gov/coverage/preventive-care-benefits/">preventive services</a>, like shots and screenings, for free before you’ve met your deductible.
</p>
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If you’ve met your deductible and have continued paying copayments until you’ve reached your <a href="https://www.healthcare.gov/glossary/premium/">out-of-pocket maximum</a>, you won’t have to pay for anything else after that; your insurance plan will. Another term worth knowing is <a href="https://www.healthcare.gov/glossary/premium/">premium</a>, the amount you pay every month for health insurance coverage.
</p>
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Always remember to check if a doctor is covered by your insurance before you make an appointment. If you go to an out-of-network provider <a href="https://www.patientadvocate.org/explore-our-resources/understanding-health-insurance/out-of-network-costs-and-how-to-handle-them-2/">you may be responsible</a> for paying the full amount of the service <a href="https://help.ihealthagents.com/hc/en-us/articles/223661067-What-Happens-if-I-Go-To-an-Out-of-Network-Provider-">or other costs</a>. Should you receive a massive medical bill by surprise, Elise, co-host of the podcast <a href="https://www.instagram.com/kindaadultingpod/?hl=en"><em>Kinda Adulting</em></a>, suggests calling your medical provider and requesting a payment plan instead of paying the large sum at once — or worse, not paying it at all. “Because it will get to collections,” says Elise, who, along with her co-hosts, Jordan and Simone, asked that their last names not be used in order to avoid conflicts with their employers. Also, she says, make sure you have your health insurance card ready when dealing with doctors’ offices and billing departments.
</p>
<h3 id="KEYMgF">
Cooking basics
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ab2Qjp">
A major part of living away from your parents is knowing how to feed yourself. Mairanz suggests always keeping your kitchen stocked with the basics of your typical diet. (Meaning, if you’re gluten-intolerant or dairy-free, you won’t want to stock up on bread or milk even if they are considered staples.) This can include eggs, pasta, chicken, and frozen veggies. Make sure you have the appropriate tools to make these foods, too: frying pan, pots, microwave, baking tray.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="rsUhJb">
Beyond having the necessary equipment, think about your lifestyle and what kind of cooking habits you’ll have. If you work two jobs and only have time to pick up a bite on the go, you might be better suited allocating your food budget for takeout, premade meals, or kits. If you genuinely enjoy cooking and food shopping, your dollars will go further at the grocery store. “A lot of it gets back to budgeting to where you’re putting your dollar and your time budget as well,” Bellaire says.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="YH1pgs">
Accustomed to grocery shopping with her family, Jordan, of the <em>Kinda Adulting</em> podcast, had to learn to shop and cook for one once she moved out on her own. Buying in bulk and storing copious leftovers occupies precious space in what may be a small apartment and refrigerator, so only buy what you need to feed yourself for the week. “Look on YouTube so you can see how people are preparing things if you don’t have somebody that you can learn from in person,” Jordan says. Elise frequently uses <a href="https://www.hellofresh.com/recipes">HelloFresh recipes</a> for inspiration, since they’re often portioned for a single diner, and then purchases the ingredients on her own.
</p>
<h3 id="hPFeOa">
Making a phone call
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="S6qLMN">
A popular topic in Mairanz’s adulting course is how to make a phone call. “We’re in more of a digital age and with online booking and texting, people talk on the phone less,” she says, “but there are times that this is something that has to be done.” From doctors’ appointments to customer service requests, feeling comfortable talking to another human on the phone is a must.
</p>
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Mairanz suggests writing down the main points you want to discuss in the call ahead of time and to be prepared for either talking to another person or leaving a voicemail. Your script can be as simple as “Hi, I’m a customer and I just received a bill that I think is incorrect. Could I speak to someone who can review and explain my bill?” Be prepared with your account information and questions about next steps.
</p>
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For voicemails, Elise suggests leaving your full name, repeating your phone number twice, your email address, and the reason for your call.
</p>
<h3 id="2yL0o7">
Build new structure
</h3>
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If you’ve been living at home for a significant chunk of time, you’ve developed set patterns and dynamics. Maybe your parents always bought the groceries and did your laundry; there were expectations and standards. On your own, you’re going to need to rebuild these frameworks.
</p>
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Regardless if you’re living with roommates, a partner, or solo, have a discussion both with your housemates and with yourself about how your home is going to operate, says clinical psychologist <a href="https://www.drjamiegoldstein.com/">Jamie Goldstein</a>, author of <a href="https://bookshop.org/books/how-to-adult-a-practical-guide-advice-on-living-loving-working-and-spending-like-a-grown-up/9781647397210"><em>How to Adult, A Practical Guide: Advice on Living, Loving, Working, and Spending Like a Grown-Up</em>.</a> When are cleaning days? When will you go food shopping? What day are you doing laundry? What guests are able to visit and how long are you comfortable with them staying? “That structure can then follow you out into the world of other dynamics that you’re navigating,” she says.
</p>
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<a href="https://www.vox.com/even-better/23310442/vox-conversations-boundaries-nedra-glover-tawwab-even-better">Setting these home boundaries</a> with yourself and others lays the foundation for maintaining limits in other relationships, like work and romance.
</p>
<h3 id="RWO8Pj">
Interpersonal skills
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="mBV1eU">
Early adulthood comes with many new faces and responsibilities. For those first moving out of their parents’ house, they’re <a href="https://www.vox.com/even-better/23279320/roommate-tips-getting-along-chores">navigating living with new people</a>. Professional environments place people of different ages, experience levels, and backgrounds in one place. <a href="https://www.vox.com/23184875/dating-pandemic-tips-better-dater">Dating as an adult</a> is rife with interpersonal misfires. One of the greatest skills young people can have is learning how to navigate these relationships, Goldstein says.
</p>
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Two keys to navigating the murky waters of real-world conversations, Goldstein says, are to engage with curiosity and learning to deal with discomfort. Some conversations will be hard, but she advises entering them not by accusing another person, but by hearing them out and learning from their experience. “The world of ‘adulting’ can be a really uncomfortable place to be, and you’re navigating all of these relationships and situations that bring you a heck of a lot of discomfort,” she says. “Discomfort of figuring out your budget, discomfort of how am I going to split groceries with roommates, discomfort of these <a href="https://www.vox.com/even-better/23161444/splitting-home-chores-unfair-equitable">dishes have to get done</a>, but they’re not my dishes, and how do we deal with that and talk about that?”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="n15UJ2">
Goldstein is also a proponent of running your errands in person instead of shopping online, to get the benefit of interacting with others. There’s value in feeling confident approaching an employee at a store to ask if they have a shirt in your size or if there’s a restroom available. You’re practicing asking questions and potentially hearing “no” and troubleshooting from there.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Puf73J">
When you’re engaging with store employees or customer service reps, maintain your composure even if you’re frustrated and feel like your requests are not being met, says Simone, another co-host of <em>Kinda Adulting</em>. “My mom always tells me to ignore attitudes,” Simone says. “I just keep going on with what I have to do. That’s a part of adulting: you’re dealing with [customer] service all the time, and a lot of times it’s not the best and you have something to accomplish.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="1iiUiN">
These skills aren’t as easily Google-able as budgeting spreadsheets, but are equally as important to living a successful adult life. Because these conversations and relationships are so difficult, you might stumble and say something you regret, or act in a way that exacerbates the problem. Be kind to yourself and others when these missteps occur (because they will). Another thing they don’t teach you in school: even in adulthood, everyone’s still learning.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="yGUi9y">
<a href="http://www.vox.com/even-better"><em>Even Better</em></a><em> is here to offer deeply sourced, actionable advice for helping you live a better life. Do you have a question on money and work; friends, family, and community; or personal growth and health? Send us your question by filling out this </em><a href="https://docs.google.com/forms/d/e/1FAIpQLSfiStGSlsWDBmglim7Dh1Y9Hy386rkeKGpfwF6BCjmgnZdqfQ/viewform"><em>form</em></a><em>. We might turn it into a story.</em>
</p></li>
<li><strong>What Xi Jinping’s third term means for China and the world</strong> -
<figure>
<img alt="" src="https://cdn.vox-cdn.com/thumbor/bYpqWmErXwfJv1ifzn9tmlFC5UI=/336x0:3796x2595/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/71501783/GettyImages_1242937078a.0.jpg"/>
<figcaption>
People stand in front of a display of images of Chinese President Xi Jinping at the Museum of the Communist Party of China in Beijing on September 4. | Noel Celis/AFP via Getty Images
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
6 questions about the biggest political event of the year.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="2DHVPU">
The biggest political event of the year is happening this weekend — and it’s not an election.
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="cT0gBN">
Beginning on October 16, some 2,300 delegates from around China will assemble in Tiananmen Square’s Great Hall of the People for the Chinese Communist Party’s <a href="https://www.bbc.com/news/world-asia-62970531">week-long</a> Party Congress. After much <a href="https://macropolo.org/analysis/most-consequential-political-event-of-the-year/">behind-the-scenes deliberations among party elites</a>, the choices for China’s <a href="https://thediplomat.com/2022/10/what-to-watch-for-at-the-20th-party-congress-the-leadership-shuffle/">top leadership</a> for the next five years will be presented to the country. The party will also review last term’s progress and set out its domestic and foreign policy goals for the next one. Decisions on both policy and personnel will be finalized officially in the spring.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="lVGuJ5">
The stakes of what happens during this Congress for China and the rest of the world will probably be the most momentous in decades. President <a href="https://www.bbc.com/news/world-asia-pacific-11551399">Xi Jinping</a>, who has <a href="https://www.reuters.com/world/china/ways-chinas-xi-jinping-amassed-power-over-decade-2022-10-10/">more personal power</a> over China than any leader since Mao Zedong, is expected to be confirmed to serve an <a href="https://www.reuters.com/world/china/ways-chinas-xi-jinping-amassed-power-over-decade-2022-10-10/">unprecedented third term</a>.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="qXmZeJ">
“The question is: How elevated will Xi Jinping be?” said <a href="https://quincyinst.org/author/mswaine/">Michael Swaine</a>, the director of the East Asia program and an expert on Chinese defense and foreign policy at the Quincy Institute for Responsible Statecraft. “There’s going to be a lot of continuity with a probable strengthening of his position.”
</p>
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China has changed dramatically under Xi’s now <a href="https://www.bloomberg.com/features/2022-xi-jinping-chongqing-ccp/?sref=qYiz2hd0">decade-long rule</a>. Xi will likely laud his administration’s success on <a href="https://thediplomat.com/2021/09/how-successful-was-chinas-poverty-alleviation-drive/">ending extreme poverty</a>, <a href="https://www.vox.com/future-perfect/2022/9/29/23375616/china-climate-adaptation-heat-wave-future">tackling climate change</a>, <a href="https://thediplomat.com/2022/05/chinas-anti-corruption-campaign-tigers-flies-and-everything-in-between/">curbing corruption</a>, and, at least <a href="https://www.nbcnews.com/news/world/china-2nd-quarter-gdp-covid-lockdowns-rcna38352">until recently</a>, <a href="https://www.theguardian.com/commentisfree/2019/dec/31/decade-china-west-china-ascent">growing the economy</a>. Despite its <a href="https://thediplomat.com/2020/04/chinas-early-covid-19-struggles-have-an-all-too-mundane-explanation/">initial missteps</a> in containing the virus, China’s <a href="https://www.vox.com/future-perfect/23057000/beijing-covid-zero-lockdown-china-pandemic">zero-Covid guidelines</a> succeeded at limiting mortality from Covid-19 compared to many other countries, though that success has come with <a href="https://www.nytimes.com/2022/10/01/world/asia/china-covid-zero.html">serious economic and political side effects</a>. China also transformed its foreign policy and became the world’s largest creditor with <a href="https://www.vox.com/future-perfect/23279714/biden-global-infrastructure-development-g7-china-belt-road-explained">the Belt and Road Initiative</a>, a massive global infrastructure and development program.
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During Xi’s time in power, however, China has also become more nationalist, authoritarian, and repressive. The government has engaged in what many critics, including the United States, have called <a href="https://www.vox.com/future-perfect/2022/9/14/23351153/china-uyghur-muslim-genocide-xinjiang-united-nations">genocide</a> toward the Uyghurs and other Muslim ethnic minority groups in Western China and crushed any semblance of autonomy <a href="https://www.vox.com/2022/7/2/23192550/xi-hong-kong-john-lee-china">in Hong Kong</a>. Abroad, China has become more assertive of territorial claims in the <a href="https://www.cfr.org/global-conflict-tracker/conflict/tensions-east-china-sea">East</a> and <a href="https://www.cfr.org/global-conflict-tracker/conflict/territorial-disputes-south-china-sea">South China Seas</a>, engaged in <a href="https://www.washingtonpost.com/world/asia_pacific/india-china-clash-sikkim/2021/01/25/7d82883c-5edb-11eb-a177-7765f29a9524_story.html">border skirmishes with India</a>, and most notably, ratcheted up military action and <a href="https://www.aljazeera.com/news/2022/8/10/china-reaffirms-threat-of-military-force-to-take-taiwan">threatening to use force</a> to bring Taiwan under its control.
</p>
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Given that all of the major policy and personnel decisions have already been made behind the scenes, the best way to think about the Party Congress is as a weather forecast for China and the world. Internally, China is dealing with significant <a href="https://www.bbc.com/news/world-asia-china-62830775">economic issues</a>, partly as a consequence of its strict zero-Covid policies and a <a href="https://www.ft.com/content/e9e8c879-5536-4fbc-8ec2-f2a274b823b4">real estate crisis</a>. It’s also facing more <a href="https://www.vox.com/future-perfect/2022/9/29/23375616/china-climate-adaptation-heat-wave-future">climate catastrophes</a> and a looming demographic collapse as <a href="https://www.weforum.org/agenda/2022/07/china-population-shrink-60-years-world/">its population appears to have begun to decline</a>. Externally, China finds itself with frostier relations with the US and European Union — its largest trading partners — while the Global North’s <a href="https://www.pewresearch.org/global/2022/09/28/how-global-public-opinion-of-china-has-shifted-in-the-xi-era/">public opinion of China has soured</a> because of its pandemic response.
</p>
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This year’s Party Congress will begin to make clear whether and how Xi and the Chinese government will reframe their approach to a world that has hugely changed since the last Party Congress five years ago. Xi “still recognizes that China must remain an international player in many, many different ways in order to succeed,” Swaine said. “He cannot isolate China and turn it into a sort of self-contained entity.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="BBk76N">
To learn more about the future of China, I spoke with Swaine about what to expect and how Xi views the current geopolitical moment. Our conversation has been edited for length and clarity.
</p>
<h4 id="5mPhdt">
Muizz Akhtar
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ZLSHvn">
What does a third term for Xi Jinping mean? Why is it such a big deal?
</p>
<h4 id="zxG0Kn">
Michael Swaine
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Ik94kX">
Under normal circumstances, at least in recent decades, Xi Jinping would be stepping down, but of course, he will not. What this means is that Xi Jinping is truly a very powerful, dominant figure within the Chinese Communist Party. He will likely continue to exercise that dominance over the next five years, at least. He may <a href="https://asia.nikkei.com/Editor-s-Picks/China-up-close/Xi-Jinping-sends-shock-waves-with-his-2035-manifesto">even stay in power until 2035</a>, which is one big milestone or benchmark that the party has put in its development plans. What that really does suggest is that he’s continuing to make and remake the party in some ways in his own image, but also put his supporters in positions of power. That’s really the critical other issue: to what extent will people seen as very loyal and beholden to him be put even more so in positions of power through the Party Congress?
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="3iXvUn">
This is not just a question of Xi Jinping having removed any possible opponents to himself and put in his own supporters. Large numbers of the party leadership support the general thrust of Xi Jinping’s direction and his governance. His whole role has been to strengthen party leadership and party control within China to correct the corruption, the backsliding, and the confusion that emerged over recent decades as to what the party’s role is in society, the economy, in politics, and foreign policy. His whole tenure has really been focused on strengthening the party and leading China into the 21st century.
</p>
<h4 id="wjHMKA">
Muizz Akhtar
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="6AKqnM">
So it sounds pretty much like we know what’s going to happen — at least the top line. Can we expect any surprises? Is there anything we should be watching out for?
</p>
<h4 id="Uej9pV">
Michael Swaine
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="s9ecBJ">
There aren’t really any individuals in the leadership who you can say are opposing factions. He has essentially eliminated those kinds of potential leaders, like <a href="https://madeinchinajournal.com/2021/01/11/the-chongqing-model-one-decade-on/">Bo Xilai</a> and other people from the past, who might have been able to challenge him in any really significant way.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jOCb9C">
What people look for in terms of changes are individuals who are perhaps not so closely tied to Xi Jinping, who are more in the realm of technocrats or reformers, who are interested in [the question of]: “How do we really try to maintain market incentives and China’s role in the global trading system while we’re sort of increasing party control?”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="S8uS4p">
Today, it’s really all about your stance toward specific policy questions, issues of economic reform, how much success you’re having in your policies at home and overseas. So Xi Jinping’s future rests more with his policy failure or success than it does with his power relationships with other factions.
</p>
<h4 id="qIqy2n">
Muizz Akhtar
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="PWPPbN">
How has Xi maintained his support in the CCP in spite of the domestic crises that have come about? I’m thinking about the economic problems, real estate bubble, and fallout from the zero-Covid policies.
</p>
<h4 id="mM5bUA">
Michael Swaine
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Xjmcpz">
I wouldn’t go so far as to say that everybody moves in lockstep, and nobody’s unhappy and there’s no grumbling going on in the ranks or among some fairly high leaders. China is encountering increasing numbers of both domestic and foreign problems, in part because of Xi Jinping’s policies. Over time, if these continue and they worsen — say, zero-Covid, which I think the Party Congress will continue to back, continues to grate a lot of people in the country, and it expands in nature — these things could rebound against Xi Jinping over time. But I would not say that at this point in time, that there is a movement afoot, let’s say, to sort of challenge Xi Jinping on policy issues.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="5leSwz">
It’s a qualified leadership. His leadership is strong, and is likely to get stronger in many ways if the policies don’t fall apart. And there’s all sorts of arguments as to whether the economy is going to tank or whether relations with the West are becoming so strained that it creates problems for China domestically. But if that doesn’t happen, you’re still probably going to get Xi Jinping ruling, but the policy questions will remain.
</p>
<h4 id="9fzFmr">
Muizz Akhtar
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="1PPkP1">
Why does what happens at this Party Congress matter to China’s broader population? What will tell us about China’s domestic trajectory under Xi?
</p>
<h4 id="SJXsOE">
Michael Swaine
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="62QHTb">
There are several issues. The first one is that Xi Jinping is connected to very specific types of policies and visions for China’s future. Like <a href="https://www.cfr.org/excerpt-third-revolution">the grand rejuvenation of China</a>, which he hopes to achieve by 2049, the elimination of inequality so that you have a more just society, corruption, etc. All of those things are going to be continued under Xi Jinping. And those have important consequences for Chinese society.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xXrWyl">
It also involves a very strong role for the party. There’s greater effort to try to control the activities of interest groups in China and the activities of institutions. All of this is something that does grate up against what some people regard as the importance of some level of free communication and some level of market-based activity.
</p>
<h4 id="TdXgMv">
Muizz Akhtar
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="CGftK8">
What does this mean for China’s relationship with the United States and the world more broadly?
</p>
<h4 id="BC9EwM">
Michael Swaine
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="osPclY">
You’ll see continuity with what’s been established under Xi Jinping already, which is that China is fully committed to engaging the world, and pursuing “<a href="https://www.fmprc.gov.cn/mfa_eng/zxxx_662805/202209/t20220924_10771028.html">win-win</a>” outcomes. It wants to invest more in the world and be a part of the world community. At the same time, it wants to see changes in some of the norms and standards that have governed in certain areas in the direction of greater justice as defined by the Chinese, which means justice for developing societies and developing countries, and justice for China’s own influence — in other words, giving China greater say at the seat of the table.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="V8KkCD">
Alongside that, you’ll have the desire to preserve and protect China against what is seen now as efforts by the United States to contain the development of the People’s Republic of China. The Communist Party will define US policy as not just anti-party but anti-China.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="gZjRi4">
So the Chinese government under Xi Jinping will continue to try to guard against greater levels of US pressure because they see the US struggling with its own problems internally, and in other ways, China’s leadership sees the United States as potentially more dangerous. Which is exactly the same kind of argument that people [in the US] project against China’s leadership. I think both of those arguments are overblown, but they do get some traction within the leaderships of both of these governments. And so the competition between the US and China will deepen and the danger of continuing down this route is that it really does pose some serious dangers, particularly over Taiwan.
</p>
<h4 id="22Pvpf">
Muizz Akhtar
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="btxFGQ">
What do you think the media gets wrong about the 20th Party Congress and political succession in China?
</p>
<h4 id="m7ahlx">
Michael Swaine
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="vFSSC3">
The media often tends to take a very sort of one-dimensional and simplistic look at the way the party exists and how it operates in China. Yes, the Party Congress is kind of a showcase more than it is a deliberative body. But the party in China is nearly 100 million people. This is not a small elite group of power-hungry people at the top of the system who are keeping everybody down; it is deeply infused in Chinese society in many ways that are in some respects seen by ordinary Chinese as good and beneficial. This is no doubt a one-party dictatorship — there’s no question about it. They do not tolerate dissent, either in words or inactions.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="tlcKPA">
However, the policies of the party, that representation at local levels, how they interact with this Chinese society at the root level, is much more complex than that simple narrative of a dictatorial one-party, top-down system. The media needs to appreciate that complexity more and understand that the party is, in many ways, serving the interests of Chinese society, while at the same time in some ways threatening the future of China because of this heavy-handedness that is exercised under Xi Jinping.
</p></li>
<li><strong>What we learned from the Walker-Warnock debate</strong> -
<figure>
<img alt="Herschel Walker Campaigns For Senator Of Georgia With Nikki Haley" src="https://cdn.vox-cdn.com/thumbor/FCeXcA6jNrzLfJ6amXwCyWRG0W8=/334x0:5667x4000/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/71500587/1243073901.0.jpg"/>
<figcaption>
Herschel Walker speaks at a campaign event on September 9, 2022 in Gwinnett, Georgia. | Megan Varner/Getty Images
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Despite his antics, Walker outperformed low expectations.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4omQD7">
In a debate punctuated as much by theatrics as real issues, Sen. Raphael Warnock (D-GA) faced off against first-time senate candidate and former professional football player Herschel Walker, highlighting the crucial role Georgia plays in the struggle over control in the Senate — which seems to be slipping out of Democrats’ grasp.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="tTscYO">
For months leading up to the debate, it was unclear whether Walker, a frequently nonsensical public speaker prone to promoting lies related to the 2020 election, <a href="https://apnews.com/article/lifestyle-sports-nfl-college-football-coronavirus-pandemic-5e2875eec11e93f9a3bf1fc859137ff8">his business ventures</a>, and on Friday night, his connections with law enforcement agencies would even debate Warnock, the Savannah-born pastor of Atlanta’s historic Ebenezer Baptist Church, as <a href="https://www.politico.com/news/2022/10/14/walker-warnock-georgia-abortion-00061971">Politico’s Natalie Allison reported</a>.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="vdqCBb">
However, Walker outperformed low expectations on the debate stage in Savannah, mainly opting to repeatedly tie Warnock to President Joe Biden by emphasizing Warnock’s voting record, and by attempting to call into question Warnock’s spiritual bona fides. Warnock focused on Walker’s repeated lies, about everything from whether he had asked a former girlfriend to have an abortion to <a href="https://www.forbes.com/sites/nicholasreimann/2022/10/15/herschel-walker-prop-badge-candidate-has-long-record-of-claiming-to-be-a-cop-hes-not/?sh=25cbb4e211fa">Walker’s claims that he was an FBI agent and worked for the Cobb County Police Department</a>, despite there being no record of him working there.
</p>
<div id="GZ1QoP">
<blockquote class="twitter-tweet">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" dir="ltr" lang="en">
Raphael Warnock: “One thing I have not done — I have never pretended to be a police officer. And I’ve never threatened a shootout with the police.”<br/><br/>Herschel Walker: [pulling out a badge prop, in violation of debate rules] “I am work with many police officers.”<a href="https://twitter.com/hashtag/GASenDebate?src=hash&amp;ref_src=twsrc%5Etfw">#GASenDebate</a> <a href="https://t.co/pyUzXkw7yT">pic.twitter.com/pyUzXkw7yT</a>
</p>
— Keith Boykin (<span class="citation" data-cites="keithboykin">@keithboykin</span>) <a href="https://twitter.com/keithboykin/status/1581068149599875072?ref_src=twsrc%5Etfw">October 14, 2022</a>
</blockquote></div></li>
</ul>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="lSIu6w">
Walker’s law enforcement claims led to the viral moment of the night; in response to Warnock’s point that he himself had never falsely claimed to be a member of law enforcement, Walker whipped out what his campaign later <a href="https://www.nytimes.com/2022/10/15/us/walker-warnock-debate-police-badge.html">told the New York Times</a> was an honorary sheriff’s badge, given in appreciation of community service Walker performed for one of Cobb County, Georgia’s law enforcement offices. Though he claimed it was proof that he worked with police, the debate moderators <a href="https://www.washingtonpost.com/politics/walker-warnock-meet-for-only-debate-in-georgia-senate-race/2022/10/14/9a021cc6-4bd2-11ed-8153-96ee97b218d2_story.html">admonished him to put the badge away</a>, reminding him of the rules against props.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4c84sx">
“If anything, it’s good that we at least got a debate in this race — in a lot of other key races across the country, it’s hard to get candidates to sit and debate anymore,” Miles Coleman, who works for Sabato’s Crystal Ball, which provides nonpartisan political analysis through the University of Virginia’s Center for Politics, told Vox.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="l412oM">
Georgia’s senate race is one of three close midterm elections that could deliver a stronger Democratic majority — or put the chamber in Republican control. Though typically the midterm elections swing Congress to the opposite party of the current president, that’s not necessarily a given in this contest; factors including the Supreme Court’s decision to overturn <em>Roe v. Wade,</em> the impact of former President Donald Trump’s influence in the Republican party, and the Republican candidates themselves have made the contests in Georgia, Pennsylvania, and Nevada in particular difficult to predict.
</p>
<h3 id="jBIXUv">
Democrats are facing tough races, despite unappealing GOP candidates
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="f9HIMy">
Walker, the one-time high school all-American and current Trump ally, has struggled with terrible press coverage in recent weeks, primarily over allegations that he requested a former girlfriend have an abortion in 2009, and paid for the procedure when she agreed. Walker has denied the incident, originally reported <a href="https://www.thedailybeast.com/pro-life-herschel-walker-paid-for-girlfriends-abortion-georgia-senate">by the Daily Beast</a>, in Friday’s debate; since the original allegations came out, the same<strong> </strong>woman has also said that Walker asked her to have a second abortion in 2011. When she refused, they ended their relationship, and she told the <a href="https://www.nytimes.com/live/2022/10/07/us/elections-midterms">New York Times</a> earlier this month that Walker has barely been involved in their child’s life other than paying child support and sending occasional gifts. One of his other children, <a href="https://www.instagram.com/christianwalk1r/?hl=en">Christian Walker</a>, who is a conservative internet celebrity, <a href="https://twitter.com/christianwalk1r/status/1577104266543497216">also claimed that Walker threatened his son and ex-wife with violence and engaged in extramarital affairs</a>.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Ax6bW7">
That’s in contrast with Walker’s support of what his website calls “<a href="https://www.teamherschel.com/issues/stand-for-conservative-family-values/">conservative family values</a>” and <a href="https://www.nytimes.com/2022/10/14/us/politics/georgia-debate-badge-key-moments.html">his previous position</a> that abortion should be banned without exception. During the debate, he seemed to soften his previous stance to be more in line with what the Georgia legislature has passed — <a href="https://www.nytimes.com/2022/07/20/us/georgia-abortion-ban.html">a six-week abortion ban</a> with exceptions for the life of the pregnant person, or in cases of rape or incest.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="6j3yzQ">
Though Walker’s personal life is rife with baggage — the abortion and abuse allegations, his struggles with <a href="https://apnews.com/article/lifestyle-sports-nfl-college-football-coronavirus-pandemic-5e2875eec11e93f9a3bf1fc859137ff8">dissociative identity disorder</a>, and his dubious business claims — he widely professes his Christian faith and has the backing of Trump and <a href="https://www.nytimes.com/2022/10/10/us/herschel-walker-evangelical-christians-georgia.html">conservative organizations like the Family Research Council</a>.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xkGITF">
Walker’s <a href="https://nymag.com/intelligencer/2022/10/herschel-walkers-desperate-religious-counterattack.html">profession of faith and his narrative of redemption</a> seem to offer cover for his past indiscretions; furthermore, as with Trump, the politically prominent <a href="https://www.nytimes.com/2022/10/10/us/herschel-walker-evangelical-christians-georgia.html">Christian Evangelical community has proved itself willing to overlook otherwise disqualifying flaws for the sake of consolidating power</a>. The GOP overall <a href="https://www.nytimes.com/live/2022/10/04/us/elections-midterms#herschel-walker-abortion-allegation-georgia-senate">quickly mobilized to stand behind Walker</a> despite the allegations, and the <a href="https://www.nytimes.com/2022/10/13/us/politics/senate-republicans-fundraising.html">Senate Leadership Fund</a>, a super PAC associated with Senate Majority Leader Mitch McConnell, has already booked $34 million in ad buys in Georgia, according to<a href="https://www.nytimes.com/live/2022/10/04/us/elections-midterms#herschel-walker-abortion-allegation-georgia-senate"> the New York Times.</a>
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="uEQaYQ">
“One of the key stories that has emerged this cycle is the quote-unquote low candidate quality on the Republican side. I think, of the Republicans who fall into that category, I think Walker might be the most palatable — I think Blake Masters, for example, he comes across as a 4chan guy,” Coleman said of the Trump-backed Arizona Republican candidate. “He seemed very apocalyptic and distant. Dr. Oz as well, there’s something that comes up with him every week, and he doesn’t seem genuine.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="sg1vxS">
Oz, who is competing against current Lt. Gov. John Fetterman (D) for one of Pennsylvania’s senate seats, likely can’t win that race, according to Sabato’s Crystal Ball, but the Nevada seat is considered a toss-up, Coleman said. “Nevada tends to be a very straight-ticket race, it’s a race where getting out your base is important.” But this contest is the first after the death of former Senate Majority Leader Harry Reid (D), and his signature get-out-the-vote operation may not be enough to keep Sen. Catherine Cortez Masto’s seat <a href="https://www.washingtonpost.com/elections/2022/10/12/nevada-midterms-democrats-republicans/">in the face of high inflation and Republican gains with Latinx voters in the state</a>.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="aAxwQn">
Whether Walker’s many failings as a candidate, as well as his latest scandals, can appreciably move the needle in Warnock’s direction remains to be seen, although recent polling indicates Warnock has a slight lead over Walker <a href="https://www.nytimes.com/2022/10/14/briefing/herschel-walkers-senate-midterms.html">due at least in part to Walker’s recent media attention</a>. In fact, Sabato’s Crystal Ball, has the Georgia race as a toss-up as of Saturday, Coleman said.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="izn98o">
However, there are weeks to go until the elections, and <a href="https://www.ft.com/content/c6608a00-d705-4fb1-a5f6-b6e842b56385">economic issues like inflation have begun to affect voters more</a>; the consumer price index, or CPI, which measures inflation on consumer goods like groceries and fuel, <a href="https://www.nytimes.com/live/2022/10/13/business/inflation-cpi-report">showed that prices rose 8.2 percent this year through the end of September</a>. Grocery, rent, and fuel costs will likely remain high as winter settles in, and the cost of borrowing money is set to increase as well <a href="https://www.wsj.com/articles/inflation-report-seals-case-for-0-75-point-fed-rate-rise-in-november-11665667815">if the Federal Reserve raises interest rates again in November</a>. Furthermore, Walker’s numbers haven’t dipped too badly, Coleman pointed out; “He hasn’t plunged, he’s maybe lost two or three points over the last week.”
</p>
<h3 id="q5rYnr">
Georgia politics are shifting
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="T5zGbS">
Georgia, which has a Republican governor and went for Trump in 2016, went Democratic in the 2020 election; a Biden victory, as well as the elections of Warnock and Sen. Jon Ossoff (D-GA) to replace Republicans Kelly Loeffler and David Perdue, turned the state solidly purple. Although Gov. Brian Kemp is likely to defeat challenger Stacy Abrams, it’s quite possible that Georgia voters will again split their ballots as they did in 2020, Coleman told Vox.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="HvDlYL">
“Something you have to keep in mind, I think is in the Atlanta suburbs, counties like Cobb, Gwinnett, there are Democratic voters there who used to be Republicans,” Coleman said. “I think what might help Warnock there is, unlike Abrams, he’s running against a Trump-backed opponent.” Kemp, meanwhile, isn’t as closely tied with the Trump brand, which works to his advantage among this group, Coleman said. “I’m really interested to see, the voters who are excited about Kemp, who are deciding whether they’re going to have to hold their nose and vote for Herschel Walker.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="wqt2PJ">
Walker’s scandals “probably will make it harder for him to win outright,” Coleman told Vox, but Georgia’s election laws require state candidates to win a majority of the vote, or face a runoff as both Warnock and Ossoff did in 2020. If Warnock fails to capture that 50 percent during the November contest, Walker could conceivably gain ground before a runoff.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="PQ68Yf">
<a href="https://www.forbes.com/sites/brucelee/2022/10/15/herschel-walker-asked-about-insulin-costs-says-you-got-to-eat-right/?sh=18e45e51dff5">Walker’s appeal as a candidate is extremely limited</a>, but, Coleman said, “He has some goodwill from his time as a football star, and that might play with older Georgians.” It’s also possible that he’ll pick up support among Black voters in rural Georgia, a group that backed Warnock in 2020. Walker’s attempt to “chip away at Warnock’s image as a preacher” was important because these areas, stretching from Columbus to Macon and up to Augusta, went stronger for Warnock than they did for Ossoff or Biden, and collecting some of those votes could be important.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="HvGZ5s">
Indeed, some Black voters — mostly men, as Leah Wright Rigueur, an associate research professor at Johns Hopkins University <a href="https://www.theatlantic.com/culture/archive/2020/11/why-black-men-and-women-vote-so-differently/617134/">explained in a piece for the Atlantic in 2020</a> — have drifted to the GOP in recent years. That’s due, according to Wright Rigueur’s research, to disillusionment with a Democratic party that has failed to achieve anything resembling equality for Black people, despite its promises and reliance on the Black community to win elections. Republicans, at least, encourage an appealing, if illusory, vision of achievable hypercapitalist wealth and independence.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="TE80aN">
Among the factors that could shift the tide in Georgia’s race — new Walker scandals, a changing voter demographic — Friday’s debate isn’t likely to be one of them, Coleman said. “Not a lot of people watch these — I think in this case, they were planning it at the same time as a Braves game.”
</p>
<h1 data-aos="fade-right" id="from-the-hindu-sports">From The Hindu: Sports</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>T20 World Cup | 11-year-old bowls to Rohit Sharma at nets</strong> - India will take on Australia and New Zealand on October 17 and 19 in the two official warm-ups ahead of tournament</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>India’s marksmen will make a mark at Paris 2024, says Jeppesen</strong> - Norwegian ace all praise for Narang’s Gun For Glory trainees’ dedication to the sport</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Sindhu waxes eloquent on Jwala’s ‘excellent academy’</strong> - International-standard facilities, coaching staff, ambience come in for high praise from champion shuttler</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Twenty20 World Cup | ‘Historic day’ as Namibia stuns Sri Lanka in opening game</strong> - The African minnows are on course for a second straight Super 12 place</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Regasa, Cheptai win elite races at Delhi Half Marathon</strong> - Regasa won the race with a time of 1 hour 30 seconds, while Cheptai came up with a personal best of 1:06:42 to top the women's event.</p></li>
</ul>
<h1 data-aos="fade-right" id="from-the-hindu-national-news">From The Hindu: National News</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Health Ministry not to procure fresh COVID-19 vaccines; surrenders ₹4,237 crore from vaccination budget</strong> - The Health Ministry is surrendering nearly 85% of the 2022-23 budget allocation for inoculation purposes to the Finance Ministry</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Tri-junction in Wayanad forest turns to be a major gateway of drugs</strong> - Drug mafia is reportedly using various routes on the State’s border to smuggle in drugs from other States</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>BJP puts out animation video of Rahul Gandhi on ‘Bharat Jodo Yatra’</strong> - Congress slams video as frustration, desperation of BJP</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Surgical tool in body cavity: panel formed to inquire into suspected medical negligence</strong> - Woman had undergone Caesarean section surgery at Kozhikode Government Medical College Hospital five years ago</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>BJP leader Arun Singh mocks Bharat Jodo Yatra as Rahul Gandhi’s ‘morning and evening walk’</strong> - BJP General Secretary and Karnataka-in-charge Arun Singh said Congress was facing a wave of defeat while BJP was riding the wave of victory</p></li>
</ul>
<h1 data-aos="fade-right" id="from-bbc-europe">From BBC: Europe</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>How Ukraine is winning the social media war</strong> - Despite civilian and military bloodshed, Ukraine’s online information war keeps a sense of humour.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Ukraine war: Russian’s exhausting ordeal to escape conscription</strong> - This young man calls the Ukraine invasion a ‘war against our own people’.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Belgorod shooting: Gunmen kill 11 in attack on Russian trainee soldiers</strong> - Two attackers opened fire on recruits who had volunteered to fight in Ukraine, local media report.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Kyiv told to save electricity after Russian missile strike</strong> - A power installation near Ukraine’s capital was heavily damaged by another Russian missile strike.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Greece: Vehicles dragged into the sea as flash floods hit Crete</strong> - At least one person is killed as heavy rains hit the Greek island.</p></li>
</ul>
<h1 data-aos="fade-right" id="from-ars-technica">From Ars Technica</h1>
<ul>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>“The hell with it”—Elon Musk to keep funding Ukrainian Starlink service [Updated]</strong> - “we’ll just keep funding Ukraine govt for free” - <a href="https://arstechnica.com/?p=1890216">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>New, transparent AI tool may help detect blood poisoning</strong> - The algorithm scans electronic records and may reduce sepsis deaths. - <a href="https://arstechnica.com/?p=1889636">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Removing notes from Mendelssohn overture shows plight of humpback whales</strong> - <em>Hebrides Redacted</em> is meant to show “how human activities have silenced nature.” - <a href="https://arstechnica.com/?p=1890094">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Since Crew Dragon’s debut, SpaceX has flown more astronauts than anyone</strong> - “Thank you for an incredible ride up to orbit and an incredible ride home.” - <a href="https://arstechnica.com/?p=1890316">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Apple’s AR/VR headset will scan your iris when you put it on</strong> - Apple’s headset will also scan users’ legs for inclusion in virtual space. - <a href="https://arstechnica.com/?p=1890235">link</a></p></li>
</ul>
<h1 data-aos="fade-right" id="from-jokes-subreddit">From Jokes Subreddit</h1>
<ul>
<li><strong>Where can you still get gas for $1.39?</strong> - <!-- SC_OFF -->
<div class="md">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Taco Bell
</p>
</div>
<!-- SC_ON -->
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/laugh_at_this_user"> /u/laugh_at_this_user </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/y55imp/where_can_you_still_get_gas_for_139/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/y55imp/where_can_you_still_get_gas_for_139/">[comments]</a></span></p></li>
<li><strong>I’m not having much luck with jobs lately.</strong> - <!-- SC_OFF -->
<div class="md">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
I wasn’t suited to be a tailor.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
The muffler factory was just exhausting.
</p>
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I couldn’t cut it as a barber.
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I didn’t have the patience to be a doctor.
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I wasn’t a good fit in the shoe factory even though I put my soul into it.
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The paper shop folded. Pool maintenance was too draining.
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I got fired from the cannon factory.
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And I just couldn’t see any future as a historian.
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/vect77"> /u/vect77 </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/y4ska6/im_not_having_much_luck_with_jobs_lately/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/y4ska6/im_not_having_much_luck_with_jobs_lately/">[comments]</a></span></p></li>
<li><strong>What does a robot do after sex</strong> - <!-- SC_OFF -->
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He nuts and bolts…
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/Opening-Archer9830"> /u/Opening-Archer9830 </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/y57jur/what_does_a_robot_do_after_sex/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/y57jur/what_does_a_robot_do_after_sex/">[comments]</a></span></p></li>
<li><strong>A man dies one day and finds himself in Hell, much to his surprise.</strong> - <!-- SC_OFF -->
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The man has never sinned, he has attended church somewhat regularly and often gives to charity.
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He asks at the gate if there has been a mistake to which the ferryman gives no answer.
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He figures there is little hope for him, but somehow he will make the best of his situation.
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He greets every demon with a smile, learns all of their names, he finds ways to keep himself somehow entertained as he is tortured, like counting every tile in the wall (yes, hell has masonry)
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He’s been there a while, it’s hard to measure eternity until one day he spots The Devil himself.
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He goes up and introduces himself, saying that despite everything it’s an honour to meet him.
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The devil returns the greeting and they make some idle small talk, until the man asks: “In all of Eternity, what is the one thing you are most proud of accomplishing?”
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The devil smiles and replies simply “I convinced humanity that there was an alternative to this”.
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/Affectionate_Crow327"> /u/Affectionate_Crow327 </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/y59akk/a_man_dies_one_day_and_finds_himself_in_hell_much/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/y59akk/a_man_dies_one_day_and_finds_himself_in_hell_much/">[comments]</a></span></p></li>
<li><strong>A cook gets married and the bride is a virgin.</strong> - <!-- SC_OFF -->
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On the wedding night, she cowers under the bed sheets as her husband undresses. He climbs in bed and tries to gently reassure her.
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“Darling,” he says, “I know this is your first time and you are very frightened but I promise you, I’ll give you anyting you want, I’ll do anyting you want. What you want?”
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“I would like number 69,” she replies shyly.
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He says, “You want beef with broccolli?”
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/vect77"> /u/vect77 </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/y4vn1h/a_cook_gets_married_and_the_bride_is_a_virgin/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/y4vn1h/a_cook_gets_married_and_the_bride_is_a_virgin/">[comments]</a></span></p></li>
</ul>
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