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<title>16 March, 2021</title>
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<title>Covid-19 Sentry</title><meta content="width=device-width, initial-scale=1.0" name="viewport"/><link href="styles/simple.css" rel="stylesheet"/><link href="../styles/simple.css" rel="stylesheet"/><link href="https://unpkg.com/aos@2.3.1/dist/aos.css" rel="stylesheet"/><script src="https://unpkg.com/aos@2.3.1/dist/aos.js"></script></head>
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<h1 data-aos="fade-down" id="covid-19-sentry">Covid-19 Sentry</h1>
<h1 data-aos="fade-right" data-aos-anchor-placement="top-bottom" id="contents">Contents</h1>
<ul>
<li><a href="#from-preprints">From Preprints</a></li>
<li><a href="#from-clinical-trials">From Clinical Trials</a></li>
<li><a href="#from-pubmed">From PubMed</a></li>
<li><a href="#from-patent-search">From Patent Search</a></li>
</ul>
<h1 data-aos="fade-right" id="from-preprints">From Preprints</h1>
<ul>
<li><strong>Absence of evidence or methodological issues? Commentary on “Stay-at-home policy is a case of exception fallacy: an internet-based ecological study”</strong> -
<div>
We read with interest the paper written by Savaris et al. entitled “Stay-at-home policy is a case of exceptional fallacy: an internet-based ecological study”[1]. We believe that the topic of whether non-pharmaceutical interventions (NPIs) have an impact on COVID-19 mortality is a key metric that is important to measure, and applaud the authors for attempting to do so. However, we believe that several key deficiencies within the methodology make the conclusions – that the authors found no evidence that COVID-19 deaths were reduced by staying at home – largely meaningless. In this letter we explain the deficiencies in the analysis, and why the methodology may be inadequate to detect an effect even if it were to exist.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/63efj/" target="_blank">Absence of evidence or methodological issues? Commentary on “Stay-at-home policy is a case of exception fallacy: an internet-based ecological study”</a>
</div></li>
<li><strong>Social isolation during COVID-19 lockdown impairs cognitive function</strong> -
<div>
Studies examining the effect of social isolation on cognitive function typically involve older adults and/or specialist groups (e.g., expeditions). We considered the effects of COVID-19-induced social isolation on cognitive function within a representative sample of the general population. We additionally considered how participants ‘shielding’ due to underlying health complications, or living alone, performed. We predicted that performance would be poorest under strictest, most-isolating conditions. At five timepoints over 13 weeks, participants (N=342; aged 18-72 years) completed online tasks measuring attention, memory, decision-making, time-estimation, and learning. Participants indicated their mood as ‘lockdown’ was eased. Performance typically improved as opportunities for social contact increased. Interactions between participant sub-groups and timepoint demonstrated that performance was shaped by individuals’ social isolation levels. Social isolation is linked to cognitive decline in the absence of ageing covariates. The impact of social isolation on cognitive function should be considered when implementing prolonged pandemic-related restrictive conditions.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/wh3gt/" target="_blank">Social isolation during COVID-19 lockdown impairs cognitive function</a>
</div></li>
<li><strong>Effects of COVID-19 Public Health Safety Measures on Births in Scotland between March and May 2020</strong> -
<div>
Objective: To combat the wide-spread transmission of COVID-19, many countries, including the United Kingdom, have imposed nationwide lockdowns. Little is known about how these public health safety measures affect pregnant mothers and their offspring. This study aimed to explore the impact of COVID-19 public health safety measures on births in Scotland. Study Design: Cohort Study Methods: Using routinely collected health data on pregnancy and birth in Scotland, this study compares all births (N = 11220) between March and May 2020 to births in the same period in 2018 (N = 12428) to investigate the potential negative effects of public health safety measures introduced in Scotland in spring 2020. Birth outcomes were compared using Mann-Whitney-U tests and chi-square tests. Results: Mothers giving birth during the pandemic tended to combine breastfeeding and formula-feeding rather than exclusively breastfeed or exclusively formula-feed, stayed in hospital for fewer days and more often had an epidural or a spinal anaesthetic compared to women giving birth in 2018. Conclusion: Overall, results suggest little impact of public health safety measures on birth outcomes. Further research is needed to explore the longer-term impacts of being born in the pandemic on both maternal mental health and child development.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://psyarxiv.com/7c5nf/" target="_blank">Effects of COVID-19 Public Health Safety Measures on Births in Scotland between March and May 2020</a>
</div></li>
<li><strong>Pituitary insufficiency as a complication of COVID-19</strong> -
<div>
We here report a case of multiple endocrine disorders—hypopituitarism with multiple hormone insufficiency and primary hypogonadism—that developed after recovery from respiratory failure in an individual with COVID-19.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/6ycrf/" target="_blank">Pituitary insufficiency as a complication of COVID-19</a>
</div></li>
<li><strong>A map of direct SARS-CoV-2 protein interactions implicates specific human host processes</strong> -
<div>
Key steps in viral propagation, immune suppression and pathology are mediated by direct, binary physical interactions between viral and host proteins. To understand the biology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, we generated an unbiased systematic map of binary physical interactions between viral and host interactions, complementing previous co-complex association maps by conveying more direct mechanistic understanding and enabling targeted disruption of direct interactions. To this end, we deployed two parallel strategies, identifying 205 virus-host and 27 intraviral binary interactions amongst 171 host and 19 viral proteins, with orthogonal validation by an internally benchmarked NanoLuc two-hybrid system to ensure high data quality. Host proteins interacting with SARS-CoV-2 proteins were enriched in various cellular processes, including immune signaling and inflammation, protein ubiquitination, and membrane trafficking. Specific subnetworks provide new hypotheses related to viral modulation of host protein homeostasis and T-cell regulation. The direct virus-host protein interactions we identified can now be prioritized as targets for therapeutic intervention. More generally, we provide a resource of systematic maps describing which SARS-CoV-2 and human proteins interact directly.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.03.15.433877v1" target="_blank">A map of direct SARS-CoV-2 protein interactions implicates specific human host processes</a>
</div></li>
<li><strong>Structure, Mechanism and Crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase</strong> -
<div>
The global COVID-19 pandemic is caused by the SARS-CoV-2 virus and has infected over 100 million and caused over 2 million fatalities worldwide at the point of writing. There is currently a lack of effective drugs to treat people infected with SARS-CoV-2. The SARS-CoV-2 Non-structural protein 13 (NSP13) is a superfamily1B helicase that has been identified as a possible target for anti-viral drugs due to its high sequence conservation and essential role in viral replication. In this study we present crystal structures of SARS-CoV-2 NSP13 solved in the APO form and in the presence of both phosphate and the non-hydrolysable ATP analogue (AMP-PNP). Comparisons of these structures reveal details of global and local conformational changes that are induced by nucleotide binding and hydrolysis and provide insights into the helicase mechanism and possible modes of inhibition. Structural analysis reveals two pockets on NSP13 that are classified as “druggable” and include one of the most conserved sites in the entire SARS-CoV-2 proteome. To identify possible starting points for anti-viral drug development we have performed a crystallographic fragment screen against SARS-CoV-2 NSP13 helicase. The fragment screen reveals 65 fragment hits across 52 datasets, with hot spots in pockets predicted to be of functional importance, including the druggable nucleotide and nucleic acid binding sites, opening the way to structure guided development of novel antiviral agents.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2021.03.15.435326v1" target="_blank">Structure, Mechanism and Crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase</a>
</div></li>
<li><strong>Sleeping for Two Structured Study Protocol</strong> -
<div>
Insomnia and sleep disturbances are common in pregnancy and have potentially significant consequences for both maternal and infant health. There is limited research examining the effectiveness of cognitive behavioural therapy for insomnia (CBT-I) during pregnancy. With increased distress and limited access to services during the COVID-19 pandemic, there is also an unprecedented need for telehealth delivery of treatment programs for pregnant women. The primary aim of the trial is to evaluate the impact of in-person or telehealth cognitive behavioural therapy for insomnia (CBT-I) versus a treatment as usual (TAU) control group in reducing symptoms of insomnia experienced in pregnancy. We hypothesize that participants who receive CBT-I delivered in person or via telehealth will report fewer insomnia symptoms. The secondary aims are to investigate if CBT-I versus TAU increases gestational length and reduces symptoms of depression. We hypothesize that receiving CBT-I will be associated with longer gestational length (as confirmed by public health records) and lower depressive symptoms.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://psyarxiv.com/xdzrv/" target="_blank">Sleeping for Two Structured Study Protocol</a>
</div></li>
<li><strong>Developing an accuracy-prompt toolkit to reduce COVID-19 misinformation online</strong> -
<div>
Recent research suggests that shifting users’ attention to accuracy increases the quality of news they subsequently share online. Here we help develop this initial observation into a suite of deployable interventions for practitioners. We ask (i) how prior results generalize to other approaches for prompting users to consider accuracy, and (ii) for whom these prompts are more versus less effective. In a large survey experiment examining participants’ intentions to share true and false headlines about COVID-19, we identify a variety of different accuracy prompts that successfully increase sharing discernment across a wide range of demographic subgroups while maintaining user autonomy. Research questions: * There is mounting evidence that inattention to accuracy plays an important role in the spread of misinformation online. Here we examine the utility of a suite of different accuracy prompts aimed at increasing the quality of news shared by social media users. * Which approaches to shifting attention towards accuracy are most effective? * Does the effectiveness of the accuracy prompts vary based on social media user characteristics? Summary: Using survey experiments with N=9,070 American social media users (quota-matched to the national distribution on age, gender, ethnicity, and geographic region), we compared the effect of different treatments designed to induce people to think about accuracy when deciding what news to share. Participants received one of the treatments (or were assigned to a control condition), and then indicated how likely they would be to share a series of true and false news posts about COVID-19. We identified three lightweight, easily-implementable approaches that each increased sharing discernment (the quality of news shared, measured as the difference in sharing probability of true versus false headlines) by roughly 50%, and a slightly more lengthy approach that increased sharing discernment by close to 100%. We also found that another approach that seemed promising ex ante (descriptive norms) was ineffective. Furthermore, gender, race, partisanship, and concern about COVID-19 did not moderate the effectiveness of the accuracy prompts, while the prompts were more effective for participants who were more attentive, reflective, engaged with COVID-related news, concerned about accuracy, college-educated, and middle-aged. From a practical perspective, our results suggest a menu of accuracy prompts that are effective in our experimental setting and that technology companies could consider testing on their own services.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://psyarxiv.com/sjfbn/" target="_blank">Developing an accuracy-prompt toolkit to reduce COVID-19 misinformation online</a>
</div></li>
<li><strong>Enhancing qualities of consciousness during online learning via multisensory interactions</strong> -
<div>
Online-learning is a feasible alternative to the physical classroom during this current global COVID-19 pandemic. In this time, Information Technologies have allowed sharing experiences but has also highlighted some limitations compared to the traditional way of learning. Learning is strongly sustained by some qualities of consciousness such as flow (intended as the optimal state of absorption and engagement in activity) and sense of presence (feeling of exerting control, interacting with and getting immersed into real/virtual environments), together with the need for social interaction. During online learning, feelings of disconnection, social isolation, distractions, lack of control exert a detrimental effect on the ability to reach the state of flow, the feeling of presence, the feeling of social involvement. Since online environments could prevent the rising of these learning-supporting variables, this article aims at describing the role of flow, presence and social interactions during online sessions and characterizing multi sensory stimulations as a driver to cope with these issues. We argue that the use of augmented, mixed or virtual reality can support abovementioned domains of consciousness and thus counteract the detrimental effects of physical distance. Such support could be further increased by enhancing multisensory stimulation modalities within augmented and virtual environments.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://psyarxiv.com/h6c8y/" target="_blank">Enhancing qualities of consciousness during online learning via multisensory interactions</a>
</div></li>
<li><strong>Culture, COVID-19, and Collectivism: A Paradox of American Exceptionalism?</strong> -
<div>
Do geographic differences in collectivism relate to COVID-19 case and death rates? And if so, would they also replicate across states within arguably the most individualistic country in the world—the United States? Further still, what role might the U.S.’s history of ethnic strife and race-based health disparities play in either reinforcing or undermining state-level relations between collectivism and COVID-19 rates? To answer these questions, we examined archival data from 98 countries (Study 1) and the 48 contiguous United States (Study 2) on country/state-level collectivism, COVID-19 case/death rates, relevant covariates (per-capita GDP, population density, spatial dependence), and in the U.S., percent of non-Whites. In Study 1, country-level collectivism negatively related to both cases (r = -.28) and deaths (r = -.40) in simple regressions; however, after controlling for covariates, the former became non-significant (rp = -.07), but the latter remained significant (rp = -.20). In Study 2, state-level collectivism positively related to both cases (r = .56) and deaths (r = .41) in simple regressions, and these relationships persisted after controlling for all covariates except race, where a state’s non-White population dominated all other predictors of COVID-19 cases (rp = .35) and deaths (rp = .31). We discuss the strong link between race and collectivism in U.S. culture, and its implications for understanding COVID-19 responses.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://psyarxiv.com/hqcs6/" target="_blank">Culture, COVID-19, and Collectivism: A Paradox of American Exceptionalism?</a>
</div></li>
<li><strong>Modelling the complexity of pandemic-related lifestyle quality change and mental health: An analysis of a nationally representative UK general population sample</strong> -
<div>
Purpose: The COVID-19 pandemic has affected the way many individuals go about their daily lives. This study attempted to model the complexity of change in lifestyle quality as a result of the COVID-19 pandemic and its context within the UK adult population. Methods: Data from the COVID-19 Psychological Research Consortium Study (Wave 3, July 2020; N=1166) were utilised. A measure of COVID-19-related lifestyle change captured how individuals’ lifestyle quality had been altered as a consequence of the pandemic. Exploratory factor analysis and latent profile analysis were used to identify distinct lifestyle quality change subgroups, while multinomial logistic regression analysis was employed to describe class membership. Results: Five lifestyle dimensions, reflecting partner relationships, health, family and friend relations, personal and social activities, and work life were identified by the EFA, while seven classes characterised by distinct patterns of change across these dimensions emerged from the LPA: (1) Better overall (3.3%), (2) Worse except partner relations (6.0%), (3) Worse overall (2.5%), (4) Better relationships (9.5%), (5) Better except partner relations (4.3%), (6) No different (67.9%), and (7) Worse partner relations only (6.5%). Predictor variables differentiated membership of classes. Notably, classes 3 and 7 were associated with poorer mental health (COVID-19 related PTSD and suicidal ideation). Conclusions: Four months into the pandemic, most individuals’ lifestyle quality remained largely unaffected by the crisis. Concerningly however, a substantial minority (15%) experienced worsened lifestyles compared to before the pandemic. In particular, a pronounced deterioration in partner relations seemed to constitute the more severe pandemic-related lifestyle change.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://psyarxiv.com/2vw7d/" target="_blank">Modelling the complexity of pandemic-related lifestyle quality change and mental health: An analysis of a nationally representative UK general population sample</a>
</div></li>
<li><strong>Non-uniform UV-C dose across N95 facepieces can cause 2.9-log variation in SARS-CoV-2 inactivation</strong> -
<div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
During public health crises like the COVID-19 pandemic, ultraviolet-C (UV-C) decontamination of N95 respirators for emergency reuse has been implemented to mitigate shortages. However, decontamination efficacy across N95s is poorly understood, due to the dependence on received UV-C dose, which varies across the complex three-dimensional N95 shape. Robust quantification of UV-C dose across N95 facepieces presents challenges, as few UV-C measurement tools have sufficient 1) small, flexible form factor, and 2) angular response. To address this gap, we combine optical modeling and quantitative photochromic indicator (PCI) dosimetry with viral inactivation assays to generate high-resolution maps of “on-N95” UV-C dose and concomitant SARS-CoV-2 viral inactivation across N95 facepieces within a commercial decontamination chamber. Using modeling to rapidly identify on-N95 locations of interest, in-situ measurements report a 17.4 ± 5.0-fold dose difference across N95 facepieces, yielding 2.9 ± 0.2-log variation in SARS-CoV-2 inactivation. UV-C dose at several on-N95 locations was lower than the lowest-dose locations on the chamber floor, highlighting the importance of on-N95 dose validation. Overall, we couple optical simulation with in-situ PCI dosimetry to relate UV-C dose and viral inactivation at specific on-N95 locations to inform the design of safe and effective decontamination protocols.
</p>
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.03.05.21253022v2" target="_blank">Non-uniform UV-C dose across N95 facepieces can cause 2.9-log variation in SARS-CoV-2 inactivation</a>
</div></li>
<li><strong>Paired SARS-CoV-2 Spike Protein Mutations Observed During Ongoing SARS-CoV-2 Viral Transfer from Humans to Minks and Back to Humans</strong> -
<div>
A mutation analysis of a collection of SARS-CoV-2 genomes around the world via sequence, date, geographic location, and species has revealed a large number of variants from the initial reference sequence in Wuhan. It also reveals that humans infected with SARS-CoV-2 have infected mink populations in the Netherlands, Denmark, United States, and Canada. In these animals, a small set of mutations often in combination, in the spike protein receptor binding domain (RBD) has apparently transferred back into humans. The viral genomic mutations in minks observed in the Netherlands and Denmark show the potential for new mutations on the SARS-CoV-2 spike protein RBD to be introduced into humans by zoonotic transfer. Our data suggests that close attention to viral transfer from humans to farm animals and pets will be required to prevent build-up of a viral reservoir for future zoonotic transfer.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2020.12.22.424003v2" target="_blank">Paired SARS-CoV-2 Spike Protein Mutations Observed During Ongoing SARS-CoV-2 Viral Transfer from Humans to Minks and Back to Humans</a>
</div></li>
<li><strong>Cetylpyridinium chloride-containing mouthwashes reduce the infectivity of SARS-CoV-2 variants in vitro</strong> -
<div>
Oral mouthwashes decrease the infectivity of several respiratory viruses including SARS-CoV-2. However, the precise agents with antiviral activity present in these oral rinses and their exact mechanism of action remain unknown. Here we show that Cetylpyridinium chloride (CPC), a quaternary ammonium compound present in many oral mouthwashes, reduces SARS-CoV-2 infectivity by inhibiting the viral fusion step with target cells after disrupting the integrity of the viral envelope. We also found that CPC-containing mouth rinses decreased more than a thousand times the infectivity of SARS-CoV-2 in vitro, while the corresponding vehicles had no effect. This activity was effective for different SARS-CoV-2 variants, including the B.1.1.7 variant, predominant in UK, also in the presence of sterilized saliva. CPC-containing mouth rinses could therefore represent a cost-effective measure to reduce SARS-CoV-2 infectivity in saliva, aiding to reduce viral transmission from infected individuals regardless of the variants they are infected with.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2020.12.21.423779v2" target="_blank">Cetylpyridinium chloride-containing mouthwashes reduce the infectivity of SARS-CoV-2 variants in vitro</a>
</div></li>
<li><strong>Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV</strong> -
<div>
The global emergence of SARS-CoV-2 urgently requires an in-depth understanding of molecular functions of viral proteins and their interactions with the host proteome. Several individual omics studies have extended our knowledge of COVID-19 pathophysiology. Integration of such datasets to obtain a holistic view of virus-host interactions and to define the pathogenic properties of SARS-CoV-2 is limited by the heterogeneity of the experimental systems. We therefore conducted a concurrent multi-omics study of SARS-CoV-2 and SARS-CoV. Using state-of-the-art proteomics, we profiled the interactome of both viruses, as well as their influence on transcriptome, proteome, ubiquitinome and phosphoproteome in a lung-derived human cell line. Projecting these data onto the global network of cellular interactions revealed crosstalk between the perturbations taking place upon SARS-CoV-2 and SARS-CoV infections at different layers and identified unique and common molecular mechanisms of these closely related coronaviruses. The TGF-{beta} pathway, known for its involvement in tissue fibrosis, was specifically dysregulated by SARS-CoV-2 ORF8 and autophagy by SARS-CoV-2 ORF3. The extensive dataset (available at https://covinet.innatelab.org) highlights many hotspots that can be targeted by existing drugs and it can guide rational design of virus- and host-directed therapies, which we exemplify by identifying kinase and MMPs inhibitors with potent antiviral effects against SARS-CoV-2.
</div>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.biorxiv.org/content/10.1101/2020.06.17.156455v2" target="_blank">Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV</a>
</div></li>
</ul>
<h1 data-aos="fade-right" id="from-clinical-trials">From Clinical Trials</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Clinical Study in the Treatment of Patients With COVID-19</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Drug: Molixan;   Drug: Placebo<br/><b>Sponsor</b>:   Pharma VAM<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Diagnostic Performance of the ID Now™ COVID-19 Screening Test Versus Simplexa™ COVID-19 Direct Assay</strong> - <b>Condition</b>:   Covid19<br/><b>Intervention</b>:   Diagnostic Test: ID Now™ COVID-19 Screening Test<br/><b>Sponsor</b>:   Groupe Hospitalier Paris Saint Joseph<br/><b>Active, not recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Dose-Ranging Study to Assess the Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Drug: Melatonin;   Drug: Placebo<br/><b>Sponsors</b>:   State University of New York at Buffalo;   National Center for Advancing Translational Science (NCATS)<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Study to Evaluate the Efficacy and Safety of Brilacidin in Hospitalized Participants With COVID-19</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Drug: Brilacidin;   Drug: Placebo;   Drug: Standard of Care (SoC)<br/><b>Sponsor</b>:   Innovation Pharmaceuticals, Inc.<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Safety, Tolerability and Pharmacokinetics of Second Generation VIR-7831 Material in Non-hospitalized Participants With Mild to Moderate COVID-19</strong> - <b>Condition</b>:   Covid19<br/><b>Interventions</b>:   Biological: VIR-7831 (Gen1);   Biological: VIR-7831 (Gen2)<br/><b>Sponsors</b>:   Vir Biotechnology, Inc.;   GlaxoSmithKline<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>DCI COVID-19 Surveillance Project</strong> - <b>Condition</b>:   Covid19<br/><b>Intervention</b>:   Diagnostic Test: SARS-CoV-2 RT-PCR Assay for Detection of COVID-19 Infection<br/><b>Sponsors</b>:   Temple University;   Dialysis Clinic, Inc.<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Off-the-shelf NK Cells (KDS-1000) as Immunotherapy for COVID-19</strong> - <b>Condition</b>:   Covid19<br/><b>Interventions</b>:   Biological: KDS-1000;   Other: Placebo<br/><b>Sponsor</b>:   Kiadis Pharma<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Study to Assess if a Medicine Called Bamlanivimab is Safe and Effective in Reducing Hospitalization Due to COVID-19</strong> - <b>Condition</b>:   Covid19<br/><b>Interventions</b>:   Biological: Bamlanivimab;   Other: Standard of Care<br/><b>Sponsors</b>:   Fraser Health;   Fraser Health Authrority Department of Evaluation and Research Services;   Surrey Memorial Hospital Foundation;   University of British Columbia;   Centre for Health Evaluation and Outcome Sciences;   BC Support Unit;   Abcellera;   Surrey Memorial Hospital Clinical Research Unit<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Effects of Telerehabilitation After Discharge in COVID-19 Survivors</strong> - <b>Condition</b>:   Covid19<br/><b>Intervention</b>:   Other: Telerehabilitation<br/><b>Sponsor</b>:   Hacettepe University<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Corticosteroids for COVID-19</strong> - <b>Condition</b>:   Covid19<br/><b>Interventions</b>:   Drug: Prednisone;   Device: Point of Care testing device for C-reactive protein<br/><b>Sponsor</b>:   University of Alberta<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Efficacy of Adaptogens in Patients With Long COVID-19</strong> - <b>Condition</b>:   Covid19<br/><b>Interventions</b>:   Dietary Supplement: ADAPT-232 oral solution;   Other: Placebo oral solution<br/><b>Sponsors</b>:   Swedish Herbal Institute AB;   National Family Medicine Training Centre, Georgia;   Tbilisi State Medical University;   Phytomed AB<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Effectiveness of the Adsorbed Vaccine COVID-19 (Coronavac) Among Education and Law Enforcement Professionals With Risk Factors for Severity</strong> - <b>Condition</b>:   Covid19<br/><b>Intervention</b>:   Biological: Adsorbed SARS-CoV-2 (inactivated) vaccine<br/><b>Sponsors</b>:   Fundação de Medicina Tropical Dr. Heitor Vieira Dourado;   Butantan Institute<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Improved Oxygen Therapy in Covid-19</strong> - <b>Condition</b>:   Covid19<br/><b>Intervention</b>:   Other: oxygen mask<br/><b>Sponsor</b>:   Region Skane<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>COVID-19 Self-Testing Through Rapid Network Distribution</strong> - <b>Condition</b>:   Covid19<br/><b>Interventions</b>:   Behavioral: COVID-19 self-test;   Behavioral: COVID-19 test referral<br/><b>Sponsors</b>:   University of Pennsylvania;   Public Health Management Corporation<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Vitamin D3 Levels in COVID-19 Outpatients From Western Mexico</strong> - <b>Condition</b>:   Covid19<br/><b>Intervention</b>:   Dietary Supplement: Vitamin D3<br/><b>Sponsor</b>:   University of Guadalajara<br/><b>Completed</b></p></li>
</ul>
<h1 data-aos="fade-right" id="from-pubmed">From PubMed</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2 in human lung tissue</strong> - To circumvent time-consuming clinical trials, testing whether existing drugs are effective inhibitors of SARS-CoV-2, has led to the discovery of Remdesivir. We decided to follow this path and screened approved medications “off-label” against SARS-CoV-2. Fluoxetine inhibited SARS-CoV-2 at a concentration of 0.8 µg/ml significantly in these screenings, and the EC50 was determined with 387 ng/ml. Furthermore, Fluoxetine reduced viral infectivity in precision-cut human lung slices showing its…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Unique and complementary suppression of cGAS-STING and RNA sensing- triggered innate immune responses by SARS-CoV-2 proteins</strong> - The emergence of SARS-CoV-2 has resulted in the COVID-19 pandemic, leading to millions of infections and hundreds of thousands of human deaths. The efficient replication and population spread of SARS-CoV-2 indicates an effective evasion of human innate immune responses, although the viral proteins responsible for this immune evasion are not clear. In this study, we identified SARS-CoV-2 structural proteins, accessory proteins, and the main viral protease as potent inhibitors of host innate…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Resveratrol-mediated Attenuation of Superantigen-driven Acute Respiratory Distress Syndrome is Mediated by Microbiota in the Lungs and Gut</strong> - Acute Respiratory Distress Syndrome (ARDS) is triggered by a variety of agents, including Staphylococcal Enterotoxin B (SEB). Interestingly, a significant proportion of patients with COVID-19, also develop ARDS. In the absence of effective treatments, ARDS results in almost 40% mortality. Previous studies from our laboratory demonstrated that resveratrol (RES), a stilbenoid, with potent anti-inflammatory properties can attenuate SEB-induced ARDS. In the current study, we investigated the role of…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Inhibition of interferon-stimulated gene 15 and lysine 48-linked ubiquitin binding to the SARS-CoV-2 papain-like protease by small molecules: In silico studies</strong> - The SARS-CoV-2 papain-like protease (PL^(pro)) is a suitable target for drug development, and its deubiquitinating and deISGylating activities have also been reported. In this study, molecular docking was used to investigate the binding properties of a selection of dietary compounds and naphthalene-based inhibitors to the previously characterised binding site of GRL-0617. The structures of the SARS-CoV-2 and SARS-CoV PL^(pro) in complex with interferon-stimulated gene 15 (ISG15) and lysine 48…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Antiviral activity of oleandrin and a defined extract of Nerium oleander against SARS-CoV-2</strong> - With continued expansion of the coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome 2 (SARS-CoV-2), both antiviral drugs as well as effective vaccines are desperately needed to treat patients at high risk of life-threatening disease. Here, we present in vitro evidence for significant inhibition of SARS-CoV-2 by oleandrin and a defined extract of N. oleander (designated as PBI-06150). Using Vero cells, we found that prophylactic (pre-infection) oleandrin (as…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Umifenovir and coronavirus infections: a review of research results and clinical practice</strong> - Coronaviruses are known to cause acute respiratory infections. Antiviral therapy, including for COVID-19, is based on clinical practice, experimental data and trial results. The purpose of this review is to: provide and systematize actual preclinical data, clinical trials results and clinical practice for antiviral agent umifenovir (Arbidol). Databases Scopus, Web of Science, RSCI and medRxiv were used for publication searching from 2004. A meta-analysis of clinical trials results was performed….</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Tocilizumab: From Rheumatic Diseases to Covid-19</strong> - Tocilizumab is a humanised interleukin-6 receptor-inhibiting monoclonal antibody that is currently approved for the treatment of rheumatoid arthritis and other immune-related conditions. Recently, tocilizumab has been investigated as a possible treatment for severe coronavirus-induced disease 2019 (COVID-19). Despite the lack of direct antiviral effects, tocilizumab could reduce the immune-induced organ damage caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV2) infection. Until…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Cinnamon and Hop Extracts as Potential Immunomodulators for Severe COVID-19 Cases</strong> - No abstract</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Identification of the absorbed ingredients and metabolites in rats after an intravenous administration of Tanreqing injection using high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry</strong> - The metabolic profiles of Tanreqing injection, which is a traditional Chinese medicine recommended for complementary administration to treat a novel coronavirus, have remained unclear, which inhibits the understanding of the effective chemical compounds of Tanreqing injection. In this study, a sensitive high-performance liquid chromatography quadrupole time-of-flight mass spectrometry method was used to identify the compounds and metabolites in various biosamples, including plasma, bile, liver,…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>SARS-CoV-2, SARS-CoV-1, and HIV-1 derived ssRNA sequences activate the NLRP3 inflammasome in human macrophages through a non-classical pathway</strong> - Macrophages promote an early host response to infection by releasing pro-inflammatory cytokines such as interleukin-1β (IL-1β), TNF, and IL-6. The bioactivity of interleukin-1β is classically dependent upon NLRP3 inflammasome activation which culminates in caspase-1 activation and pyroptosis. Recent studies suggest a role for NLRP3 inflammasome activation in lung inflammation and fibrosis in both COVID-19 and SARS, and there is evidence of NLRP3 involvement in HIV-1 disease. Here, we show that…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Discovering Potential RNA Dependent RNA Polymerase Inhibitors as Prospective Drugs Against COVID-19: An in silico Approach</strong> - COVID-19, caused by Severe Acute Respiratory Syndrome Corona Virus 2, is declared a Global Pandemic by WHO in early 2020. In the present situation, though more than 180 vaccine candidates with some already approved for emergency use, are currently in development against SARS-CoV-2, their safety and efficacy data is still in a very preliminary stage to recognize them as a new treatment, which demands an utmost emergency for the development of an alternative anti-COVID-19 drug sine qua non for a…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Potential Therapeutic Effect of RNA Interference and Natural Products on COVID-19: A Review of the Coronaviruses Infection</strong> - The SARS-CoV-2 virus was reported for the first time in Wuhan, Hubei Province, China, and causes respiratory infection. This pandemic pneumonia killed about 1,437,835 people out of 61,308,161cases up to November 27, 2020. The disease’s main clinical complications include fever, recurrent coughing, shortness of breath, acute respiratory syndrome, and failure of vital organs that could lead to death. It has been shown that natural compounds with antioxidant, anticancer, and antiviral activities…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Artemisia annua L. extracts inhibit the in vitro replication of SARS-CoV-2 and two of its variants</strong> - CONCLUSIONS: A. annua extracts inhibit SARS-CoV-2 infection, and the active component(s) in the extracts is likely something besides artemisinin or a combination of components that block virus infection at a step downstream of virus entry. Further studies will determine in vivo efficacy to assess whether A. annua might provide a cost-effective therapeutic to treat SARS-CoV-2 infections.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The SARS-CoV-2 Y453F mink variant displays a pronounced increase in ACE-2 affinity but does not challenge antibody neutralization</strong> - SARS-CoV-2 transmission from humans to animals has been reported for many domesticated species, including farmed minks. The identification of novel spike gene mutations appearing in minks has raised major concerns about potential immune evasion and challenges for the global vaccine strategy. One genetic variant, known as “cluster-five”, arose among farmed minks in Denmark and resulted in a complete shutdown of the world’s largest mink production. However, the functional properties of this new…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Research Progress of Mesenchymal Stem Cell Therapy for Severe COVID-19</strong> - Corona Virus Disease 2019 (COVID-19) refers to a type of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. 60 million confirmed cases have been reported worldwide until November 29, 2020. Unfortunately, the novel coronavirus is so extremely contagious that the mortality rate of severe and critically ill patients was high. Thus, there is no definite and effective treatment in clinic except for antiviral therapy and supportive therapy. Mesenchymal stem…</p></li>
</ul>
<h1 data-aos="fade-right" id="from-patent-search">From Patent Search</h1>
<ul>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Peptides and their use in diagnosis of SARS-CoV-2 infection</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU319943278">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A PROCESS FOR SUCCESSFUL MANAGEMENT OF COVID 19 POSITIVE PATIENTS</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU319942709">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Sars-CoV-2 vaccine antigens</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU318283136">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>SARS-COV-2 BINDING PROTEINS</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU318004130">link</a></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Gerät zur Unterstützung und Verstärkung natürlicher Lüftung</strong> -
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
</p><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">Lüftungssystem für einen mit öffnbaren Fenstern (16) ausgestatteten Gebäuderaum, gekennzeichnet dadurch, dass es ein Gehäuse (18) und einen Ventilator (20) aufweist, wobei durch das Gehäuse eine vom Ventilator erzeugte Luftströmung strömen kann, wobei das Gehäuse dafür eine Einströmöffnung (24) für Luft und eine Ausströmöffnung (22) für Luft enthält, wobei eine der beiden Öffnungen der Form eines Öffnungsspalts (26) zwischen einem Fensterflügel (12) und einem Blendrahmen (14) des Fensters (16) angepasst ist.</p></li>
</ul>
<img alt="embedded image" id="EMI-D00000"/>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"></p>
<ul>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=DE319927546">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Compositions and methods for detecting SARS-CoV-2 spike protein</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU317343760">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>靶向SARS-CoV-2的抗体及其制备方法和应用</strong> - 本发明提供了靶向SARS‑CoV‑2的抗体及其制备方法和应用，该抗体包含VH和VL，所述VH包含以下CDR：氨基酸序列如SEQ ID NO:1、2、3所示的VH CDR1、VH CDR2、VH CDR3；所述VL包含以下的CDR：氨基酸序列如SEQ ID NO:4、5、6所示的VL CDR1、VL CDR2、VL CDR3。该抗体能够高亲和且特异地结合SARS‑CoV‑2的S蛋白的RBD，抑制RBD蛋白与受体ACE2蛋白的结合，高效地抑制SARS‑CoV‑2感染细胞，同时对潜在的免疫逃逸突变的假病毒具有很好的中和活性，从而可有效应用于SARS‑CoV‑2病毒及相关疾病的诊断、预防和治疗中。 - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=CN319687581">link</a></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>UV-Desinfektion von interaktiven Oberflächen</strong> -
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
</p><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">Desinfektionsvorrichtung (100, 200A, 200B, 300) zum Desinfizieren einer berührungsintensiven Oberfläche, umfassend: eine EWE-Vorrichtung (110) zum Emittieren von elektromagnetischen Wellen, die dafür konfiguriert ist, elektromagnetische Strahlung innerhalb des ultravioletten Spektrums (UV-Strahlung, 115) zu emittieren; und einer als Lichtleiter dienenden, mindestens teilweise für sichtbares Licht zwischen der vorderen Oberfläche (121) und der hinteren Oberfläche (122, 222) durchlässigen Scheibe (120, 220A, 220B) mit einer vorderen Oberfläche (121) und einer hinteren Oberfläche (122, 222), wobei die EWE-Vorrichtung (110) positioniert ist, um UV-Strahlung (115) in die Scheibe (120, 220A, 220B) zu emittieren, wobei die Scheibe dafür konfiguriert ist, einen Teil der von der EWE-Vorrichtung (110) empfangenen UV-Strahlung (115) in einer verteilten Art und Weise über die vordere Oberfläche (121) zu reflektieren und zu zerstreuen; und die UV-Strahlung, die von der Scheibe (120, 220A, 220B) empfangen und über die vordere Oberfläche (121) verteilt wird, zur Desinfektion der vorderen Oberfläche dient.</p></li>
</ul>
<img alt="embedded image" id="EMI-D00000"/>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"></p>
<ul>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=DE319927526">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>一种SARS-CoV-2中和抗体的检测方法、检测试剂盒</strong> - 本发明公开了一种SARS‑CoV‑2中和抗体的检测方法、检测试剂盒，属于生物医学检测技术领域。本发明公开的SARS‑CoV‑2中和抗体的检测方法是基于hACE2‑RBD放大的胶乳增强免疫比浊检测法，检测试剂盒包括SARS‑CoV‑2的S蛋白受体结合域RBD标记的第一胶乳微球和人hACE2标记的第二胶乳微球。本发明通过在胶乳微球上标记抗原，放大了检测信号，增加了检测的灵敏度，拓宽了检测范围。本发明不仅能够确定被检测者是否为感染者，还能获知被检测者感染风险。本发明对中和抗体的检测还可用于评价接种SARS‑CoV‑2疫苗后临床效果，对SARS‑CoV‑2疫苗的研发与接种，具有重大意义。 - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=CN319687385">link</a></p></li>
<li><strong>Aronia-Mundspray</strong> -
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Anordnung zum Versprühen einer Substanz in die menschliche Mundhöhle und/oder in den Rachen, dadurch gekennzeichnet, dass die Anordnung eine Sprühflasche mit einer Substanz aufweist, die wenigstens Aroniasaft und eine Alkoholkomponente aufweist.
</p>
<ul>
<li><a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=DE319581893">link</a></li>
</ul></li>
</ul>
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<h1 data-aos="fade-down" id="daily-dose">Daily-Dose</h1>
<h1 data-aos="fade-right" data-aos-anchor-placement="top-bottom" id="contents">Contents</h1>
<ul>
<li><a href="#from-new-yorker">From New Yorker</a></li>
<li><a href="#from-vox">From Vox</a></li>
<li><a href="#from-the-hindu-sports">From The Hindu: Sports</a></li>
<li><a href="#from-the-hindu-national-news">From The Hindu: National News</a></li>
<li><a href="#from-bbc-europe">From BBC: Europe</a></li>
<li><a href="#from-ars-technica">From Ars Technica</a></li>
<li><a href="#from-jokes-subreddit">From Jokes Subreddit</a></li>
</ul>
<h1 data-aos="fade-right" id="from-new-yorker">From New Yorker</h1>
<ul>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Trump and the Trapped Country</strong> - For years, we debated whether Donald Trump would topple democracy. But the threat continues to come from the system itself. - <a href="https://www.newyorker.com/news/our-columnists/trump-and-the-trapped-country">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Stimulus Bill Is the Most Economically Liberal Legislation in Decades</strong> - Biden’s bill is a sign that our democracy isn’t completely broken, and may convince Americans that government can solve problems. - <a href="https://www.newyorker.com/magazine/2021/03/22/the-stimulus-bill-is-the-most-economically-liberal-legislation-in-decades">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Why Learning Pods Might Outlast the Pandemic</strong> - It’s possible to imagine home schools becoming like sidewalk dining—an experiment that sticks. - <a href="https://www.newyorker.com/news/annals-of-education/why-learning-pods-might-outlast-the-pandemic">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Flowers for Sarah Everard</strong> - In the aftermath of a horrific kidnapping and murder, the U.K. reckons with the omnipresence of misogyny. - <a href="https://www.newyorker.com/news/letter-from-the-uk/flowers-for-sarah-everard">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Story of the Comfort Women, in Korean and Japanese</strong> - Why The New Yorker translated its recent report on a battle over history, accountability, and the legacy of the Second World War. - <a href="https://www.newyorker.com/news/news-desk/the-story-of-the-comfort-women-in-korean-and-japanese">link</a></p></li>
</ul>
<h1 data-aos="fade-right" id="from-vox">From Vox</h1>
<ul>
<li><strong>How zero-sum thinking about race hurts all Americans</strong> -
<figure>
<img alt="A black-and-white photo of a black man in swim trunks with a towel around his shoulders walking along the edge of an indoor pool." src="https://cdn.vox-cdn.com/thumbor/rozLLlnnyH5HWQf5zfVYyNwnK3I=/0x0:2492x1869/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/68973844/GettyImages_514907186.0.jpg"/>
<figcaption>
In 1958, David Isom, 19, broke the color line by using a segregated public pool, which resulted in officials promptly closing the facility. | Bettmann Archive via Getty Images
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
A conversation with Heather McGhee about the costs of America’s racial bargain.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="3a0b2D">
Black Americans are typically cast as the victims of racism. And indeed, they are victims of America’s long history of racial oppression.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Jbd4TW">
But according to Heather McGhee, that fact can obscure an important truth: White Americans also pay a tremendous price for the country’s racial hierarchy — and many don’t even realize it. It’s a self-inflicted wound that will never heal unless Americans change the way they think about race and the national project.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="sroMZ6">
McGhee is the former president of the think tank Demos and the author of a terrific new book called <a href="https://go.redirectingat.com?id=66960X1516588&amp;xs=1&amp;url=https%3A%2F%2Fwww.penguinrandomhouse.com%2Fbooks%2F564989%2Fthe-sum-of-us-by-heather-mcghee%2F&amp;referrer=vox.com&amp;sref=https%3A%2F%2Fwww.vox.com%2Fpolicy-and-politics%2F22301484%2Famerica-racism-the-sum-of-us-heather-mcghee" rel="sponsored nofollow noopener" target="_blank"><em>The Sum of Us</em></a>. The story McGhee tells orbits around a depressing metaphor: the drained swimming pool. For a good chunk of the 20th century, American towns offered grand community swimming pools as symbols of leisure and civic pride. They were testaments to public investment.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Ib9NHn">
But then desegregation happened and the pools had to be integrated. Rather than open them up to everyone, town after town simply shut them down. And not only did they close the pools, they nuked their parks departments and effectively abandoned public investment altogether. So in the end, Black Americans didn’t get to enjoy the pools, but neither did white people who were motivated by self-destructive racial ideologies.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="0Qg2bO">
This, McGhee argues, is the story of American politics in microcosm. The entire country is now one giant drained pool. Too many Americans have too easily accepted the lie animating so much of our history, namely that politics is a zero-sum contest in which one group’s gain must be another group’s loss.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="9lMVLK">
I wanted to talk through the consequences of all this with McGhee. If she’s right that “We can’t have nice things” because of this lie at the center of our shared story, then how do we transcend that lie? What story must replace it? And how can the left do a better job at persuading the white<strong> </strong>victims of this lie to let it go?
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="H593Vq">
You can hear our entire conversation in the week’s episode of<em> </em><a href="https://podcasts.apple.com/us/podcast/vox-conversations/id1081584611"><em>Vox Conversations</em></a>. A transcript, edited for length and clarity, follows.
</p>
<div id="zYZkTw">
</div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="wQKDPy">
Subscribe to <em>Vox Conversations</em> on <a href="https://apps.apple.com/us/app/vox-conversations/id1215557536">Apple Podcasts</a>, <a href="https://podcasts.google.com/search/vox%20conversations">Google Podcasts</a>, <a href="https://open.spotify.com/show/6NOJ6IkTb2GWMj1RpmtnxP">Spotify</a>, <a href="https://www.stitcher.com/show/vox-conversations">Stitcher</a>, or wherever you listen to podcasts.
</p>
<hr class="p-entry-hr" id="wjEcXG"/>
<h4 id="gvacMC">
Sean Illing
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4AivLf">
How did you come to write this book?
</p>
<h4 id="U7ngsL">
Heather McGhee
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="QKBC3x">
One of the first stops on my book journey to write <em>The Sum of Us</em> was Montgomery, Alabama, which is one of many places where there is a beautiful central park in the city. I walked the grounds, this big, wide flat expanse that used to have one of the nearly 2,000 publicly funded grand-resort-style swimming pools in America. And this was something that was a big feature of American life under the New Deal in the 1930s and ’40s and ’50s. It was just one of the many examples of a commitment to the public good by our government that was really supported by white public opinion at the time.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="T8crMV">
But like so much of the New Deal, so much of that public commitment to public goods, there was an asterisk. Public pools in many parts of the country were segregated or for whites only. Certainly this one in Montgomery, Alabama, was. And so in the 1950s and ’60s, when Black families began to win court cases saying, “Hey, those are our tax dollars too. Our families should be able to swim too,” instead of integrating the pools, many cities across the country drained their public pools rather than integrate them.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="86vMKp">
That’s what happened in Montgomery, Alabama. In fact, they drained the pool, filled it with dirt, and closed Oak Park. They sold off the animals in the zoo, shut down the entire parks and recreation department of the city, and kept it closed for a decade. They were almost to 1970 before the good people of Montgomery even got to enjoy a public park again, all because of racism.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="4vK7t9">
And to me, that’s such an example of the zero-sum thinking creating costs for everyone, turning what was a public good into a private luxury, expressing the limits of white support for public goods once those public goods were extended and available to people that they did not perceive to be good, that they had been taught for generations to disdain and distrust.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="p2ufeG">
In many ways, that’s what’s happened to our entire economy, as the majority of white voters went from supporting a job guarantee and a minimum income in the country in the late ’50s and early ’60s, to that support cratering once the civil rights movement made clear that those kinds of economic guarantees would go to Black people as well.
</p>
<h4 id="UJYixn">
Sean Illing
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="NPwi10">
That’s got to be one of the greatest and most consequential political tantrums in history.
</p>
<h4 id="8PgJTo">
Heather McGhee
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="r2RoTm">
It is. But throughout the book, I really try to put myself in the shoes of people who might, because of the stories they’d been told, because of what they believe, fit that into their moral understanding. And the more you do that, the more you recognize that in many ways, we’re still there.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="u1fguw">
Those beliefs about the inherent goodness or deservingness of people at the bottom of the economic ladder are still pretty stubborn. And they’re reflected in the majority of white people’s opinions about what a minimum-wage worker should be paid, for example. Or who should pay taxes. Or what kinds of floors we should have under the human misery of our fellow American.
</p>
<h4 id="hGT6gl">
Sean Illing
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="PB1KDj">
Your book opens with a familiar question: Why can’t we have nice things? What nice things can’t we have?
</p>
<h4 id="cFxRPA">
Heather McGhee
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="twvEej">
I don’t mean self-driving cars or laundry that does itself. I mean things like truly universal affordable health care, or world-class, or even just reliable, modern infrastructure. I mean a public health system to tackle pandemics with efficiency and scale. I mean a well-funded school in every neighborhood. I mean a representative functioning democracy that allows majoritarian views on big public questions to prevail and not get stymied in arcane Senate rules.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="8L9HxN">
These are the kinds of things that a wealthy, modern government should be able to provide for its people. And they are the types of things that this country has really failed to deliver on for all of my lifetime, and certainly for the past few generations.
</p>
<h4 id="HbFhsy">
Sean Illing
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Slot5y">
A big reason — maybe the biggest reason — for this is that Americans have internalized a story about how politics works and who deserves the privileges of citizenship. You call it a “zero-sum” story. What does that mean?
</p>
<h4 id="4fdx8e">
Heather McGhee
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="fEry3x">
The zero-sum story is the idea that there’s this massive dividing line between Black people and white people, that they’re on opposite teams, and that progress for people of color has to come at white people’s expense. It’s a story that’s still with us because it’s very profitable. Because the upshot of selling this story is that white voters cheer the destruction of supports that could benefit them if it will keep the people on the opposite team from having something that they don’t think they deserve.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="LMqDj7">
So what that has meant in practical politics has been the kind of zero-sum rhetoric that we hear from the right wing: the makers and takers, the taxpayers and freeloaders, the free stuff, the handouts, us versus them.
</p>
<h4 id="J1KenS">
Sean Illing
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ybxS6w">
We’re all products of deep cultural forces that shape us in ways we don’t understand and our identities are getting pushed and activated in ways we don’t recognize. How do you make someone aware of the illusoriness of their own identity, of their own story, without also offending who they think they are?
</p>
<h4 id="tEv6qx">
Heather McGhee
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="FZPbRm">
I think politics has a role. It’s really important that we do political messaging like the <a href="https://www.demos.org/campaign/race-class-narrative-project">Race Class Narrative project</a> that I co-developed and we housed at Demos, which was aimed at better messages for organizers and activists and candidates to beat the zero-sum scapegoating story. That’s really important.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jMYNVR">
But I met lots of white people over the course of working on this book who had actually rejected the zero-sum after growing up being steeped in it. It wasn’t because they heard the magic words in a campaign ad. It was because they had rolled up their sleeves in organizing. They had actually experienced what it’s like to trust someone who also needed the same change in their own lives.
</p>
<h4 id="PS6H4Y">
Sean Illing
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="v0iG6Z">
If I was among the richest and most powerful people in this country and I wanted to construct a pair of competing ideologies that would ensure my interests are never threatened, what we have now is what it would be: conventional white racism on the one side and what you see in some corners of the left now, which is a blanket condemnation of white privilege, or an obsession with various symbolic battles.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="w1lejT">
As you know better than anyone, if these are the terms, solidarity is unachievable and the whole plutocratic system keeps spinning.
</p>
<h4 id="U16XYz">
Heather McGhee
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="h1UnWl">
I definitely think there’s a disconnect here between the way progressive actors with microphones elevate issues on Twitter and in news coverage, and the real concerns of, say, a Black family in St. Louis. So there’s a distortion of the causes of racial justice because of the white predominance in the chattering class on the left. It’s almost like white supremacy within the activist movement is hurting the activist movement’s cause.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="mAZRPD">
My eyes were really opened to this when it comes to the role of race and racism in the environmental movement. If you’re just a casual observer, you might think that your typical environmentalist is a white guy with a fleece and a backpack, right? That’s Sierra Club, that’s the REI version of the environmentalist. It’s the upper-class family that recycles a lot and composts. That’s who’s most active on environmental issues — or at least that’s the stereotype. And it’s also because those groups are the best funded and also influential in policymaking.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ivRb65">
But when I dug into it, it turns out that white people are much less worried about climate change and supportive of taking action than Black and brown people are. So your average environmentalist, as in someone who really cares about the environment and is really supportive of taking pretty aggressive action to address this existential threat, is a Black or brown person, not an upper-class white person. So that kind of white privileging within the ranks of the movement is actually cutting off the leadership’s connection to the people who are the natural base.
</p>
<h4 id="fkSItY">
Sean Illing
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="UUSHSO">
Your book makes the incredibly important argument that racism hurts everyone, and yet what I hear over and over again from white people I engage with where I live (in the Deep South) is resentment over the notion that they’re “privileged” or tools of white supremacy. Just setting aside the merits of any of those arguments and why they’re elevated (which you just explained), the practical issue here is that these narratives function like conversation-stoppers and it’s the kind of thing I know you bump up against all the time.
</p>
<h4 id="l1hy3t">
Heather McGhee
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="CCj6g2">
You know, it’s funny because the white share of the vote to the right wing has been pretty consistent ever since Lyndon Johnson signed the Civil Rights and Voting Rights Act. So this new tendency to blame white allegiance to the GOP on the recent resurgence of racial justice in the national conversation feels a little hollow to me. Because it’s not like there were all these white people who were Democrats until <a href="https://www.vox.com/2015/5/31/17937764/ferguson-missouri-protests-2014-michael-brown-police-shooting">the protests in Ferguson</a> happened in 2014. It’s definitely made the dog whistles into bull horns, and it’s given a lot of fodder to Fox News and right-wing radio to harp on racial grievances.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="cniQi2">
But the long-term data is pretty consistent on this stuff. The majority of white moderates and conservatives say that Black people take more from society than we give. That’s not necessarily about Dr. Seuss books. This is a<strong> </strong>deeper and older projection that feels very necessary to justify the racial hierarchy.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="YOfUt5">
The kinder, gentler version of this is the old “socially liberal, fiscally conservative” line that says poverty is about culture and effort and not about wages and benefits. So this spectrum has existed for a long time now in our politics. I think it’s easier in some ways for progressives to think about what we have the power to change, which again is the discourse that’s coming from the elite, very online, mostly white progressives.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="c26ftf">
But I don’t think this is the real issue.
</p>
<h4 id="N6GFHR">
Sean Illing
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="oHJYbl">
Yeah, I don’t think it is either, it’s just particularly salient right now for lots of reasons. But it’s important to say that there’s a flip side to some of these arguments about how the left frames these issues. As you point out in the book, Obama went out of his way to deemphasize race and appeal to the best of us — and what did he get? He got a Tea Party that used the language of fiscal responsibility to organize white resentment and undermine his presidency, so there’s that.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="DeFAOD">
I’m curious if you think Obama’s story speaks to the limits of progressive nationalism?
</p>
<h4 id="ldaJhR">
Heather McGhee
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="8qGHZX">
I think it speaks to the limits of colorblind triumphalism and to our ability to have a conversation about this country within this ecosystem. I think Barack Obama understands race and always has. But I think that the Democratic Party leadership, and the mostly white people around Obama’s campaign, were so close to somebody who gave the lie to all of it. In my experience from having conversations with people who were in Obama’s circle, they really didn’t realize the extent of racism in our politics and our policymaking. They just didn’t get it.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="7RCoNf">
And they hadn’t done the work to understand just how central race and racism was, and what the tools looked like, and how they’re deployed. But they were also white and they actually had a gut-level caution around talking about race explicitly. I think there was the assumption that by not talking about it explicitly, they could avoid the mines. And that was wrong.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="pJiAfK">
That I think was the big insight that we gleaned from the Race Class Narrative project. We realized that there’s a way, and really an imperative, to engage on racism that isn’t feeding into the reactionary right-wing message but, in fact, gives white people and people of color a way to see that we’re all in this country together.
</p>
<h4 id="raQWFD">
Sean Illing
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="NIUstD">
That feels like a good place to pivot toward the solution, or the story you think we need to tell moving forward. What does that look like?
</p>
<h4 id="HvBOwR">
Heather McGhee
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ghifvc">
I think we have to tell a certain story and that story has to be heard through action. This is a point I feel I need to keep making. Because of the economics of democratic activism, there’s a lot of emphasis on getting the right message. It’s important, but it’s necessary, not sufficient.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="qCw6zy">
We need to include in our worldview the story of the drained public pool. A way of understanding that this country had hit on the formula for creating middle-class security for working-class people — and walked away from it because of racism. And that the nostalgia of the Trump message to “Make America Great Again” contains some truth that the economic data really does bear out. Economic life really was better and easier in the past. But the people who destroyed that weren’t Black or brown people or women who wanted a seat at the table. It was the white elites who used racial and gender fears and distrust to convince the majority of white voters to turn their back on that formula. So I think that is really important.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XH2phE">
We’re also in this resurgence of organizing and we have to double down. Ordinary people have experienced a rebirth of civic life. Whether they’re doing it for their own survival, or because they’re making minimum wage, or because their moral sense of self has been violated by America’s inequalities, people have decided that a part of being an American and a human being right now is to organize. And that is the space that has always changed lives and changed history. And we are in that space right now. And that’s what’s exciting and hopeful to me. It’s why I say in the book that there are solidarity dividends to be had, but only through cross-racial organizing.
</p></li>
<li><strong>The Bachelor finally had a direct conversation about racism</strong> -
<figure>
<img alt="Rachael Kirkconnell and Matt James on The Bachelor’s After the Final Rose special." src="https://cdn.vox-cdn.com/thumbor/xZ4QzxhS-HDWNjB0VT5vpaBEgN8=/160x138:2643x2000/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/68972947/158737_6932.0.jpg"/>
<figcaption>
ABC
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Confronting the show’s recent controversies was the bare minimum, but still significant.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XVONwF">
On Monday night, <a href="https://www.vox.com/2021/3/12/22308108/the-bachelor-racism-chris-harrison-rachael-kirkconnell-matt-james"><em>The Bachelor</em></a> — following a tumultuous season finale and weeks of controversy over racism — had one of its most direct conversations about race ever as the show continues to grapple with its own problems navigating this topic.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ttGrCC">
In an emotional <em>After the Final Rose</em> special, which aired live after the finale, Matt James — the first Black Bachelor in the show’s 19-year history — spoke about the unique pressures he experienced in this role as well as his reaction to the scrutiny of Rachael Kirkconnell, the winner of his season who’s <a href="https://www.vulture.com/2021/02/the-bachelors-rachael-kirkconnell-apologizes-for-racism.html">faced criticism over racist actions</a> that have surfaced from her past.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="5DU40F">
“It’s a lot of pressure,” said James, of the overwhelming expectations placed on him as the first Black Bachelor. “For a lot of people, that was the first time having someone like myself in their home. … The position I stepped into was to take on the weight of everything going on in the country in that time frame surrounding social justice and within the franchise surrounding diversity and inclusion.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="GgZqp5">
Following the revelations about Kirkconnell’s past behavior, which included attending an “Old South” antebellum party in 2018 and “liking” a social media photo of friends posing in front of a Confederate flag, James has been at the center of a firestorm that’s called attention not only to these specific allegations, but to much deeper issues around race within the <em>Bachelor</em> franchise. In particular, longtime host Chris Harrison made himself synonymous with such issues when he gave an explosive interview in February defending Kirkconnell and arguing that her actions may have been more acceptable three years ago, when she was a student.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="qvqKaW">
“Is it a good look in 2018 or is it not a good look in 2021?” Harrison asked during <a href="https://www.vulture.com/2021/02/rachel-lindsay-chris-harrison-podcast.html">a tense interview with Rachel Lindsay</a>, who in 2017 became the first Black Bachelorette and has since become a commentator about the events of the entire franchise, including its shortcomings. “It’s not a good look, ever,” Lindsay replied.
</p>
<aside id="YqCfWy">
<div>
</div>
</aside>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="M2ijFi">
In the wake of that interview, Harrison has stepped back from his hosting duties. Not only has it been announced that <a href="https://www.vulture.com/2021/03/chris-harrison-wont-return-for-the-bachelorette-next-season.html">Harrison will not be helming the next season of <em>The Bachelorette</em></a>, but he was replaced by author and former football player Emmanuel Acho on Monday’s <em>After the Final Rose</em> special. “This might just be the most uncomfortable conversation in <em>Bachelor</em> history,” Acho said as the special began, teasing his interviews with James and Kirkconnell. Acho laid out specifically, too, what exactly Kirkconnell had done by attending the “Old South” party, noting that “antebellum” translates directly to “before the war” in Latin, and refers to a time prior to the Civil War, when slavery still existed.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="GUR5vl">
James, in his comments, stressed that Kirkconnell’s actions were just as bad in 2018 as in 2021, and said he believed that she needed time and space to do the “work” and reflect on why they were harmful. “As someone who grew up in the South, it takes me to a place that I don’t often like to think about. I wasn’t okay,” James explained, adding that the two have since broken up and that he felt Kirkconnell had to reckon with her actions on her own.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="czvC9h">
“The most disappointing thing for me was having to explain to you why what I saw was problematic and why I was so upset. … And so when I questioned our relationship, it was in the context of you not fully understanding my Blackness,” James said, while speaking with Kirkconnell on <em>After the Final Rose</em>. “I don’t want to be emotionally responsible for those tears, because it’s like, the work and the reconciliation that needs to be done is one thing I can’t do for you.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="NXFcMg">
Harrison and Kirkconnell have both apologized for their actions, and Kirkconnell emphasized on Monday that she is confronting her ignorance and behavior. “I see someone who was living in this ignorance without thinking who it would be hurting,” Kirkconnell said of her attendance at the “Old South” party. “I never asked myself, ‘What is the history behind this?’” Kirkconnell reiterated that there is no excuse for her actions and rebuffed earlier comments from viewers who’ve sought to defend her by arguing that such parties have long been commonplace in the south.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="TLOJ0w">
This conversation was significant for <em>The Bachelor</em>, largely because of how much the franchise has long avoided confronting its problems with race. Those problems include casting racist contestants, amplifying stereotypes and playing into harmful tropes in storylines about contestants of color, and staying quiet on issues of discrimination and inequality.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="bc7nqz">
Just two years ago, <a href="https://www.vox.com/2020/3/10/21152628/the-bachelor-season-finale-peter-weber-madison-hannah-ann">the show aired a segment</a> about racism that never once used the word: Instead, it focused on contestants of color saying how the “hate” they received was uncomfortable.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="F8QVhP">
Monday’s <em>After the Final Rose</em> conversation was the least <em>The Bachelor</em> could have done to demonstrate that it wants to have explicit and thoughtful conversations about racism within the franchise moving forward. As the show promises to take steps to reckon with its deeper issues around race — including<a href="https://www.instagram.com/p/CMWDcDbgBCS/"> expanding the BIPOC representation among its executive producers</a> — this discussion marked a long overdue start.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="qpU7fZ">
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="KdyOge">
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="bTCbFq">
</p></li>
<li><strong>North Korea is giving Biden the silent treatment</strong> -
<figure>
<img alt="" src="https://cdn.vox-cdn.com/thumbor/qhcZoZjh3nUqJVtpWUJx0kX3TGE=/0x61:3425x2630/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/68969490/1291575359.0.jpg"/>
<figcaption>
North Korean leader Kim Jong Un in Pyongyang on March 17, 2020. | API/Gamma-Rapho/Getty Images
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
The Biden administration is calling North Korea. No one is answering.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="XVv7ms">
The Biden administration may have newly rejoined the global village, but the usually rowdy North Korean neighbors so far have greeted the Americans’ move-in with nothing but silence.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="bf3uYI">
Pyongyang has yet to acknowledge that President Joe Biden is, well, the president of the United States. And <a href="https://www.reuters.com/article/us-usa-northkorea-idUSKBN2B50P1">Reuters</a> on Saturday reported that multiple efforts by the US to directly interact with North Korea since mid-February, including through a United Nations channel, have yielded no reply.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="6txgxq">
“To date, we have not received any response from Pyongyang,” a senior administration official told me on Monday. “This follows over a year without active dialogue with North Korea, despite multiple attempts by the US to engage,” which means the Biden administration says North Korea didn’t interact with President Trump’s team for a while, either.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="wvANXt">
White House press secretary <a href="https://twitter.com/jseldin/status/1371506431824953344?s=20">Jen Psaki</a> confirmed that later in the day during her daily press conference, adding that “diplomacy continues to be our first priority.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="USdhdq">
Experts aren’t entirely sure what’s driving the quiet. One potential reason is that the North Korean regime isn’t a Biden fan — for example, a 2019 state-run news commentary called the then-presidential candidate an “imbecile” and “<a href="https://www.vox.com/2019/5/22/18635370/north-korea-joe-biden-imbecile-trump">fool of low IQ.</a>”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xXVqA0">
That came after Biden called North Korean leader Kim Jong Un a “<a href="https://www.businessinsider.com/north-korea-joe-biden-fool-kim-jong-un-tyrant-2019-5">tyrant</a>” and then, afterward, <a href="https://www.stripes.com/news/pacific/biden-calls-north-korean-leader-a-thug-but-says-he-d-meet-kim-if-denuclearization-is-agreed-1.649630">trashed his personal diplomacy with Trump</a>, which may have cooled any ideas in Pyongyang about interacting with the US right now.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="UJKiYb">
Another is that the country is in a <a href="https://www.wired.com/story/truth-about-north-koreas-ultra-lockdown-covid-19/">severe lockdown</a> to quash the coronavirus pandemic, a move that also precipitated a <a href="https://thediplomat.com/2021/01/what-is-the-truth-about-covid-19-in-north-korea/">harsh economic downturn</a>. If that’s the case, Pyongyang may prefer dealing with its domestic problems right now to engaging in complex diplomacy with Washington.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ijSpju">
“They are focused on getting through this hard period,” said Joshua Pollack, an expert on North Korea’s nuclear program at the Middlebury Institute of International Studies.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="iBABVM">
But North Korea’s silence extends beyond just rebuffing America’s entreaties.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="LAwjg3">
North Korean leader Kim Jong Un has yet to authorize a ballistic missile or nuclear test this year as a way to darkly welcome the new administration, even though <a href="https://www.vox.com/21726445/iran-north-korea-russia-afghanistan-joe-biden-foreign-policy">many experts suspected he might do so early in Biden’s tenure</a>. There’s still time for that, though, since Pyongyang sometimes waits a few months before launching its weapons in defiance.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="k68BQ5">
However, Kim’s sister, <a href="https://kcnawatch.org/newstream/1615842122-277969450/kim-yo-jong-deputy-department-director-of-cc-wpk-gives-statement-to-media/">Kim Yo Jong</a>, who holds a powerful position in the regime, did offer an oblique comment Monday aimed at the new US administration.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="pZJ783">
At the end of a lengthy media statement railing at the South Korean government for participating in annual joint military exercises with the US this month, she threw this in: “Availing myself of this opportunity, I’d like to advise the new US Administration that wants to give off powder smell in Korea across the ocean. If they want to have a good sleep for coming four years, it would be good for them not to seek something to do unseemly that may not make them sleep properly.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="3fbsi2">
This is the first of a comment directed at the president and his team since they came into office.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="nkWuPa">
It’s possible the Biden administration may not mind the general silence directed at the US, at least for now. After all, they’re also dealing with the <a href="https://www.vox.com/coronavirus-covid19">coronavirus pandemic</a>, as well as an <a href="https://www.vox.com/2021/3/1/22307070/iran-nuclear-deal-rejection-wsj-usa-european-union">intransigent Iran</a>, a looming decision over whether to <a href="https://www.vox.com/2021/3/8/22319420/afghanistan-blinken-letter-leak-peace-plan">keep US troops in Afghanistan</a>, and the <a href="https://www.vox.com/22325328/biden-quad-japan-australia-india-vaccine-rare-earth">challenge from China</a>. A dramatic North Korean provocation would just add to the president’s growing inbox.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="0LMidu">
But it’s likelier than not that Pyongyang will eventually respond. And when it does, the message likely won’t be a welcoming one.
</p>
<h3 id="7agXM5">
Biden’s team has already sent a strong signal that North Korea won’t like
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="fNufcD">
Since <a href="https://twitter.com/nktpnd/status/1363904232143880194?s=20">1992</a>, America’s policy toward North Korea has been mostly consistent: It would seek the “denuclearization of the Korean Peninsula.” Simply put, that means the US won’t station nuclear-capable warplanes in South Korea and Seoul won’t seek the bomb, all so North Korea feels comfortable enough to verifiably dismantle its nuclear arsenal.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="tNWgk2">
When Kim and former President Donald Trump met in Singapore in 2018, they signed a <a href="https://www.vox.com/world/2018/6/12/17452464/trump-kim-meeting-north-korea-agreement-denuclearization">declaration</a> in which North Korea promised to work toward such an outcome.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="GMapIJ">
But three times now the Biden administration has offered a harder-line stance than that, potentially reversing even that limited progress.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="pbVfGe">
In February, Secretary of State <a href="https://geneva.usmission.gov/2021/02/22/secretary-blinken-cd/">Antony Blinken</a> told the UN’s Conference on Disarmament that the US “remains focused on denuclearization of North Korea.” By phrasing it that way — the denuclearization of North Korea instead of the Korean Peninsula — he seemed to be suggesting that only North Korea needs to give up its nuclear weapons, while the US can still maintain its nuclear defense of South Korea.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="qSbz0s">
Last week, the US — along with its “<a href="https://www.vox.com/22325328/biden-quad-japan-australia-india-vaccine-rare-earth">Quad</a>” partners Japan, India, and Australia — released a <a href="https://www.whitehouse.gov/briefing-room/statements-releases/2021/03/12/quad-leaders-joint-statement-the-spirit-of-the-quad/">statement</a> saying, “We reaffirm our commitment to the complete denuclearization of North Korea.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="krV3eu">
And then on Sunday, a State Department press briefing about <a href="https://www.state.gov/reaffirming-the-unbreakable-u-s-japan-alliance/">Blinken and Defense Secretary Lloyd Austin’s trip to Japan</a> this week noted they would “reinvigorate trilateral cooperation on a broad range of global issues, including the denuclearization of North Korea.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ZVIeSy">
Even though Biden’s team has said its North Korea policy remains under review for a few more weeks, those statements indicate the administration has made up its mind. The goal now, it seems, is to let Pyongyang know it alone must agree to a non-nuclear future. For now at least, it looks like the Biden administration is taking a harder line than the Trump team did.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="hQ3y7i">
That might please some US allies like Japan, which prefers a tougher stance against North Korea. But Seoul, which wants to keep diplomatic channels with Pyongyang open, certainly won’t like it, and neither will Kim.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ydB6KZ">
In 2018, for example, the state-run <a href="https://kcnawatch.org/newstream/297579/it-would-be-better-to-search-for-new-way-rather-than-facing-barrier-on-old-way/?t=1573529946659">Korean Central News Agency</a> blasted the Trump administration for even suggesting that only North Korea had to give up its bombs. “When we refer to the denuclearization of the Korean peninsula, it, therefore, means removing all elements of nuclear threats from the areas of both the north and the south of Korea and also from surrounding areas from where the Korean peninsula is targeted,” the commentary read. “This should be clearly understood.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="W7fdQ7">
Thus the Biden administration’s stance, should it remain in place, could ratchet up tensions with North Korea even further.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ivBN69">
Almost no experts believe Pyongyang will ever give up its nuclear arsenal, especially since it sees those weapons as its best defense against an improbable US-led invasion. Plus, few nations voluntarily give up their nuclear weapons after spending decades to acquire and build them.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="NgydLi">
The North Korea-focused formulation “doesn’t help any, and it’s not clear why they’ve chosen this language,” said Middlebury’s Pollack. “It plays straight to [North Korea’s] complaint that the US just wants to demand their unilateral disarmament.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="GXsOnH">
The Biden administration has promised to keep conversations going with allies about its North Korea policy until it finalizes its plans. “Throughout the review process, we have and will continue to engage with our Japanese and South Korean allies to solicit input and explore fresh approaches. We have listened carefully to their ideas, including through trilateral consultations,” the senior administration official told me.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="LSXUst">
Even so, the repeated American position worries experts that a decision may have already been made by default — with potentially disastrous results.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="euHT0E">
“If this is the new formulation, I would not expect the North Koreans to reciprocate any overtures,” said Ankit Panda, an expert on North Korea’s nuclear program at the Carnegie Endowment for International Peace. “There are very few incentives to take a first step until they see a positive sign from the US.”
</p></li>
</ul>
<h1 data-aos="fade-right" id="from-the-hindu-sports">From The Hindu: Sports</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>ICC Women’s ICC ODI rankings: Punam Raut breaks into top 20 among batters</strong> - Opener Smirit Mandhana remains the top ranked Indian batter, at the seventh spot, followed by her skipper Mithali Raj, who is placed ninth</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>ICC bans UAE players Mohammad Naveed and Shaiman Anwar for eight years on match-fixing charges</strong> - The bans are related to their alleged role in trying to fix matches in the T20 World Cup qualifier in 2019</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Sri Lanka fined for slow over-rate in third ODI against West Indies</strong> - Sri Lanka have been fined 40% of their match fees for maintaining a slow over-rate against the West Indies in the third ODI in Antigua, the ICC said</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Michael Holding awarded Best pundit at British Sports Journalism Award</strong> - Holding had delivered a powerful message against racism during last year’s England-West Indies series, saying that blacks have been dehumanised and their accomplishments wiped off from a history “written by people who do the harm.”</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Messi ties Xavi’s record as Barcelona cuts Atlético’s lead</strong> - This was Messi’s 767th match.</p></li>
</ul>
<h1 data-aos="fade-right" id="from-the-hindu-national-news">From The Hindu: National News</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Yenepoya closes medical, paramedical colleges</strong> - The Yenepoya (Deemed to be University) on Monday announced that it was closing9 medical and paramedical colleges with immediate effect till further or</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>RTC employees to go on indefinite strike from April 7</strong> - KSRTC Employees League accuses State govt. of not fulfilling demands within deadline of three months</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>COVID-19: Highest losses in labour income, education, says U.N. report</strong> - It flags migrant deaths and disappearances, air quality in region India is part of</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>No move for UT of Marathi-speaking areas in Karnataka: MHA</strong> - Despite demands, no such proposal under consideration, LS told</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>From printed masks to LED symbols, activists spoilt for choice</strong> - On the bright side, all campaign materials are plastic-free</p></li>
</ul>
<h1 data-aos="fade-right" id="from-bbc-europe">From BBC: Europe</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Covid-19: Continue using AstraZeneca vaccine, says WHO</strong> - It says there is no evidence of a link to blood clots, as major EU countries pause use of the vaccine.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Dutch head to polls as Covid crisis looms large</strong> - The election comes after a government crisis and during the country’s strictest lockdown to date.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Coronavirus: St Patrick’s Day celebrations move online</strong> - There may be no parades or fanfare but events are still taking place to celebrate Ireland’s patron saint.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Stripe plots European expansion after $95bn valuation</strong> - The online payments firm, the most valuable US start-up, was founded by two Irish brothers.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>France to return Klimt painting sold under duress during Nazi era</strong> - A Jewish family was forced to sell Rosiers sous les Arbres after the Nazis annexed Austria in 1938.</p></li>
</ul>
<h1 data-aos="fade-right" id="from-ars-technica">From Ars Technica</h1>
<ul>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Many Republicans are refusing COVID vaccines. Experts are trying to change that</strong> - Straight facts and no politics are what’s needed to increase vaccination. - <a href="https://arstechnica.com/?p=1749872">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>In-kernel WireGuard is on its way to FreeBSD and the pfSense router</strong> - WireGuard probably won’t make it into 13.0-RELEASE, but 13.1 seems very likely. - <a href="https://arstechnica.com/?p=1749817">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>NASA has begun a study of the SLS rocket’s affordability [Updated]</strong> - One issue up for grabs: Should work on the Exploration Upper Stage continue? - <a href="https://arstechnica.com/?p=1749541">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>“Please someone help me.” FaceTime users bombarded with group call spam</strong> - Apple doesn’t provide tools that effectively ease a major headache for FaceTime users. - <a href="https://arstechnica.com/?p=1749815">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Report: Indian government is planning outright ban on cryptocurrency</strong> - The proposed bill would ban trading, mining, and even holding cryptocurrencies. - <a href="https://arstechnica.com/?p=1749805">link</a></p></li>
</ul>
<h1 data-aos="fade-right" id="from-jokes-subreddit">From Jokes Subreddit</h1>
<ul>
<li><strong>In a freak accident today, a photographer was killed when a huge lump of cheddar landed in him</strong> - <!-- SC_OFF -->
<div class="md">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
To be fair though, the people who were being photographed did try to warn him
</p>
</div>
<!-- SC_ON -->
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/bob9109"> /u/bob9109 </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/m5xnxw/in_a_freak_accident_today_a_photographer_was/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/m5xnxw/in_a_freak_accident_today_a_photographer_was/">[comments]</a></span></p></li>
<li><strong>I always thought that Steve Jobs would make a better president than Donald Trump</strong> - <!-- SC_OFF -->
<div class="md">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
but then I realized that I’m comparing apples to oranges
</p>
</div>
<!-- SC_ON -->
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/AntiHeroLBC"> /u/AntiHeroLBC </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/m60m7x/i_always_thought_that_steve_jobs_would_make_a/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/m60m7x/i_always_thought_that_steve_jobs_would_make_a/">[comments]</a></span></p></li>
<li><strong>Son: “Mom, Dad, I’m gay.”</strong> - <!-- SC_OFF -->
<div class="md">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Mom: <em>Stares at Dad</em>
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Dad: <em>Clenches fist</em>
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Mom: “Don’t!”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Dad: <em>Sweats Profusely</em>
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Mom: “…”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Dad: “HI GAY, I’M DAD”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Son: “No dad, I’m serious!”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Dad: “You’re serious? I thought you were Gay!”
</p>
</div>
<!-- SC_ON -->
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/Pyrross"> /u/Pyrross </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/m5v4tn/son_mom_dad_im_gay/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/m5v4tn/son_mom_dad_im_gay/">[comments]</a></span></p></li>
<li><strong>I brought my girlfriend home to meet my family.</strong> - <!-- SC_OFF -->
<div class="md">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
They criticized everything she did, mocked her heritage and gave her a psychiatric disorder.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
I guess I shouldn’t have insisted on the royal treatment.
</p>
</div>
<!-- SC_ON -->
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/slimeslug"> /u/slimeslug </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/m5op3q/i_brought_my_girlfriend_home_to_meet_my_family/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/m5op3q/i_brought_my_girlfriend_home_to_meet_my_family/">[comments]</a></span></p></li>
<li><strong>My wife bet me that I wouldn’t dare give our daughter a silly name.</strong> - <!-- SC_OFF -->
<div class="md">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
So I decided to call her Bluff.
</p>
</div>
<!-- SC_ON -->
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/YZXFILE"> /u/YZXFILE </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/m5z5p2/my_wife_bet_me_that_i_wouldnt_dare_give_our/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/m5z5p2/my_wife_bet_me_that_i_wouldnt_dare_give_our/">[comments]</a></span></p></li>
</ul>
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