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<h1 data-aos="fade-down" id="covid-19-sentry">Covid-19 Sentry</h1>
<h1 data-aos="fade-right" data-aos-anchor-placement="top-bottom" id="contents">Contents</h1>
<ul>
<li><a href="#from-preprints">From Preprints</a></li>
<li><a href="#from-clinical-trials">From Clinical Trials</a></li>
<li><a href="#from-pubmed">From PubMed</a></li>
<li><a href="#from-patent-search">From Patent Search</a></li>
</ul>
<h1 data-aos="fade-right" id="from-preprints">From Preprints</h1>
<ul>
<li><strong>The Indonesian Government’s Defense Economic Program for the Small Business Economy During the Covid-19 Pandemic for Economic Resilience</strong> -
<div>
The Indonesian government always pays attention and focuses on the context of economic recovery during the Covid-19 Pandemic to MSMEs so that they are able to rise from adversity and be able to reabsorb workers who have lost their jobs during the COVID-19 pandemic. Many businesses, especially Micro, Small and Medium Enterprises, went bankrupt and closed their businesses due to demand from consumers who fell free. This study uses the strategy theory of Lykke, 1989 which includes 3 (three) aspects of Ends, Ways and Means, with descriptive qualitative methods. various strategies. This paper aims to discuss the importance of the Government’s Strategy in helping Micro, Small and Medium Enterprises during the COVID-19 pandemic in order to survive and continue to increase their business in supporting Indonesia’s economic resilience. The results achieved are the need to improve strategies on Ways, including the right strategy starting with a regulatory framework and incentives in the form of policies in legislation, government regulations that are comprehensive and sustainable in helping the MSME sector to survive and get out of difficulties during the Covid pandemic. -19 so that it can support the economic resilience of the Indonesian people and nation.
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<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/dbvmq/" target="_blank">The Indonesian Government’s Defense Economic Program for the Small Business Economy During the Covid-19 Pandemic for Economic Resilience</a>
</div></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>One wave or another in the pandemic: Psychological well-being during the third COVID-19 wave</strong> -
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After a year from the emergence of the Coronavirus disease (COVID-19) on February 2020, between March and May 2021 Italy faced its third wave of infections. Previous studies have shown that in the first phases of the pandemic certain factors had a protective role against distress. However, as the months in the pandemic went by, people’s feelings and experiences significantly changed and little is known regarding the role of possible protective variables after prolonged pandemic situations. In the present study we aimed to investigate the impact of several behavioral variables on individuals’ mental states and emotions experienced during the third COVID-19 wave in Italy. 454 Italian adults were asked questions regarding the intensity of mental states and emotions experienced, the perceived usefulness of lockdown, the feeling of living a normal life, and the coping strategies implemented to face the pandemic. Using a data driven approach, we calculated the best model on the participation of each factor in explaining participants’ emotions and mental states. Our findings indicate that the presence of acceptance attitudes toward restrictive measures and the implementation of recreational activities helped participants face a prolonged pandemic with positive emotions.
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</ul>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://psyarxiv.com/tbcx7/" target="_blank">One wave or another in the pandemic: Psychological well-being during the third COVID-19 wave</a>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The statistical analysis of daily data associated with different parameters of the New Coronavirus COVID-19 pandemic in Georgia and their monthly interval prediction from September 1, 2021 to December 31, 2021</strong> -
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The lockdown introduced in Georgia on November 28, 2020 contributed to positive trends in the spread of COVID-19 until February - the first half of March 2021. Then, in April-May 2021, the epidemiological situation worsened significantly, and from June to the end of December COVID - situation in Georgia was very difficult. In this work results of the next statistical analysis of the daily data associated with New Coronavirus COVID-19 infection of confirmed (C), recovered (R), deaths (D) and infection rate (I) cases of the population of Georgia in the period from September 01, 2021 to December 31, 2021 are presented. It also presents the results of the analysis of monthly forecasting of the values of C, D and I. As earlier, the information was regularly sent to the National Center for Disease Control &amp; Public Health of Georgia and posted on the Facebook page https://www.facebook.com/Avtandil1948/. The analysis of data is carried out with the use of the standard statistical analysis methods of random events and methods of mathematical statistics for the non-accidental time-series of observations. In particular, the following results were obtained. Georgia9s ranking in the world for Covid-19 monthly mean values of infection and deaths cases in investigation period (per 1 million population) was determined. Among 157 countries with population ≥ 1 million inhabitants in October 2021 Georgia was in the 4 place on new infection cases, and in September - in the 1 place on death. Georgia took the best place in terms of confirmed cases of diseases (thirteenth) in December, and in mortality (fifth) - in October. A comparison between the daily mortality from Covid-19 in Georgia from September 01, 2021 to December 31, 2021with the average daily mortality rate in 2015-2019 shows, that the largest share value of D from mean death in 2015-2019 was 76.8 % (September 03, 2021), the smallest 18.7 % (November 10, 2021). As in previous work [9,10] the statistical analysis of the daily and decade data associated with coronavirus COVID-19 pandemic of confirmed, recovered, deaths cases and infection rate of the population of Georgia are carried out. Maximum daily values of investigation parameters are following: C = 6024 (November 3, 2021), R = 6017 (November 15, 2021), D = 86 (September 3, 2021), I = 12.04 % (November 24, 2021). Maximum mean decade values of investigation parameters are following: C = 4757 (1 Decade of November 2021), R = 4427 (3 Decade of November 2021), D = 76 (2 Decade of November 2021), I = 10.55 % (1 Decade of November 2021). It was found that as in spring and summer 2021 [9,10], from September to December 2021 the regression equations for the time variability of the daily values of C, R, D and I have the form of a tenth order polynomial. Mean values of speed of change of confirmed -V(C), recovered - V(R), deaths - V(D) and infection rate V(I) coronavirus-related cases in different decades of months for the indicated period of time were determined. Maximum mean decade values of investigation parameters are following: V(C) = +139 cases/day (1 Decade of October 2021), V(R) = +124 cases/day (3 Decade of October 2021), V(D) = +1.7 cases/day (3 Decade of October 2021), V(I) = + 0.20 %/ day (1 decades of October 2021). Cross-correlations analysis between confirmed COVID-19 cases with recovered and deaths cases shows, that from September 1, 2021 to November 30, 2021 the maximum effect of recovery is observed on 12 and 14 days after infection (CR=0.77 and 0.78 respectively), and deaths</p></div></li>
<li>after 7, 9, 11, 13 and 14 days (0.70≤CR≤0.72); from October 1, 2021 to December 31, 2021 - the maximum effect of recovery is observed on 14 days after infection (RC=0.71), and deaths - after 9 days (CR=0.43). In Georgia from September 1, 2021 to November 30, 2021 the duration of the impact of the delta variant of the coronavirus on people (recovery, mortality) could be up to 28 and 35 days respectively; from October 1, 2021 to December 31, 2021 - up to 21 and 29 days respectively. Comparison of daily real and calculated monthly predictions data of C, D and I in Georgia are carried out. It was found that in investigation period of time daily and mean monthly real values of C, D and I practically fall into the 67% - 99.99% confidence interval of these predicted values. Traditionally, the comparison of data about C and D in Georgia (GEO) with similar data in Armenia (ARM), Azerbaijan (AZE), Russia (RUS), Turkey (TUR) and in the World (WRL) is also carried out.
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"></p>
<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.01.16.22269373v1" target="_blank">The statistical analysis of daily data associated with different parameters of the New Coronavirus COVID-19 pandemic in Georgia and their monthly interval prediction from September 1, 2021 to December 31, 2021</a>
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<li><strong>Background incidence rates of adverse events of special interest related to COVID-19 vaccines in Ontario, Canada, 2015 to 2020, to inform COVID-19 vaccine safety surveillance</strong> -
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Background: Background incidence rates are critical in pharmacovigilance to facilitate identification of vaccine safety signals. We estimated background incidence rates of nine adverse events of special interest related to COVID-19 vaccines in Ontario, Canada. Methods: We conducted a population-based retrospective observational study using linked health administrative databases for hospitalizations and emergency department visits among Ontario residents. We estimated incidence rates of Bells palsy, idiopathic thrombocytopenia, febrile convulsions, acute disseminated encephalomyelitis, myocarditis, pericarditis, Kawasaki disease, Guillain-Barre syndrome, and transverse myelitis during five pre-pandemic years (2015-2019) and 2020. Results: The average annual population was 14 million across all age groups with 51% female. The pre-pandemic mean annual rates per 100,000 population during 2015-2019 were 43.9 for idiopathic thrombocytopenia, 27.8 for Bells palsy, 25.0 for febrile convulsions, 22.8 for acute disseminated encephalomyelitis, 11.3 for myocarditis/pericarditis, 8.6 for pericarditis, 2.9 for myocarditis, 1.9 for Guillain-Barre syndrome, 1.7 for transverse myelitis, and 1.6 for Kawasaki disease. Females had higher rates of acute disseminated encephalomyelitis and transverse myelitis while males had higher rates of myocarditis, pericarditis, and Guillain-Barre syndrome. Bells palsy, acute disseminated encephalomyelitis, and Guillain-Barre syndrome increased with age. The mean rates of myocarditis and/or pericarditis increased with age up to 79 years; males had higher rates than females: from 12-59 years for myocarditis and 12 years and older for pericarditis. Febrile convulsions and Kawasaki disease were predominantly childhood diseases and generally decreased with age. Conclusions: Our estimated background rates will permit estimating numbers of expected events for these conditions and facilitate detection of potential safety signals following COVID-19 vaccination.
</p>
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<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.01.12.22269169v1" target="_blank">Background incidence rates of adverse events of special interest related to COVID-19 vaccines in Ontario, Canada, 2015 to 2020, to inform COVID-19 vaccine safety surveillance</a>
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<li><strong>Waning Effectiveness of SARS-CoV-2 mRNA Vaccines in Older Adults: A Rapid Review</strong> -
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The U.S. Centers for Disease Control and Prevention (CDC) and other health agencies have recently recommended a booster dose of COVID-19 vaccines for specific vulnerable groups including adults 65 years and older. There is limited evidence whether vaccine effectiveness in older adults decreases over time, especially against severe COVID-19. We performed a rapid review of published studies available through 04 November 2021 that provide effectiveness data on mRNA vaccines approved/licensed in the United States and identified eight eligible studies which evaluated vaccine effectiveness in older adults. There is evidence of a decline in vaccine effectiveness against both SARS-CoV-2 infection and severe COVID-19 in older adults among studies which analyzed data up to July-October 2021. Our findings suggest that vaccine effectiveness diminishes in older adults, which supports the current recommendation for a booster dose in this population.
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<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.01.15.22269364v1" target="_blank">Waning Effectiveness of SARS-CoV-2 mRNA Vaccines in Older Adults: A Rapid Review</a>
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<li><strong>Distinct Vaccine Efficacy Rates Among Health Care Workers During a COVID-19 Outbreak in Jordan</strong> -
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BACKGROUND: We aimed to assess the efficacy of 3 COVID-19 vaccines in a population of health care workers at a tertiary cancer center in Amman, Jordan. METHODS: We evaluated the records of 2855 employees who were fully vaccinated with 1 of 3 different vaccines and those of 140 employees who were not vaccinated. We measured the number of SARS-CoV-2 infections that occurred at least 14 days after the second vaccine dose. RESULTS The 100-day cumulative incidence of PCR-confirmed SARS-CoV-2 infections was 19.3% +/- 3.3% for unvaccinated employees and 1.7% +/- 0.27% for fully vaccinated employees. The 100-day cumulative infection rates were 0.7% +/- 0.22% in BNT162b2 vaccine recipients (n = 1714), 3.6% +/- 0.77% in BBIBP-CorV recipients (n = 680), and 2.3% +/- 0.73% in ChAdOx1 recipients (n = 456). We used Cox regression analyses to compare the risks of SARS-CoV-2 infection among the different vaccine recipient groups and found a significantly higher infection risk in BBIBP-CorV (hazard ratio [HR] = 2.9 +/- 0.31) and ChAdOx1 recipients (HR = 3.0 +/- 0.41) compared to BNT162b2 recipients (P = .00039 and .0074, respectively). Vaccinated employees who had no previously confirmed SARS-CoV-2 infections were at a markedly higher risk for breakthrough infections than those who experienced prior infections (HR = 5.7 +/- 0.73, P = .0178). CONCLUSIONS: Our study offers a real-world example of differential vaccine efficacy among a high-risk population during a national outbreak. We also show the important synergism between a previous SARS-CoV-2 infection and vaccination.
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<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.01.15.22269356v1" target="_blank">Distinct Vaccine Efficacy Rates Among Health Care Workers During a COVID-19 Outbreak in Jordan</a>
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<li><strong>Waning COVID-19 Vaccine Effectiveness for BNT162b2 and CoronaVac in Malaysia: An Observational Study</strong> -
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Evaluation of vaccine effectiveness over time against severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) infection or coronavirus disease 2019 (COVID-19) is important. Evidence on effectiveness over time for the CoronaVac vaccine is lacking despite its widespread use globally. In Malaysia, a diverse set-up of COVID-19 vaccines was rolled out nationwide, and the waning of vaccine protection is a concern. We aimed to investigate and compare waning vaccine effectiveness against COVID-19 infections, COVID-19 related ICU admission and COVID-19 related deaths for BNT162b2 and CoronaVac vaccines. In this observational study, we consolidated nationally representative data on COVID-19 vaccination and patients′ outcomes. Data on all confirmed COVID-19 cases from 1 to 30 September 2021 were used to compare vaccine effectiveness between the ′early′ group (fully vaccinated in April to June 2021) and the ′late′ group (fully vaccinated in Jul to Aug 2021). We used a negative binomial regression model to estimate vaccine effectiveness against COVID-19 infections for both ′early′ and ′late′ groups, by comparing the rates of infection for individuals vaccinated in the two different periods relative to the unvaccinated. Among confirmed COVID-19 cases, we used logistic regression to estimate and compare vaccine effectiveness against ICU admission and deaths between the two different periods. For BNT162b2, vaccine effectiveness against COVID-19 infections declined from 90.8% (95% CI 89.4, 92.0) in the late group to 79.1% (95% CI 75.8, 81.9) in the late group. Vaccine effectiveness for BNT162b2 against ICU admission and deaths were comparable between the two different periods. For CoronaVac, vaccine effectiveness waned against COVID-19 infections from 74.4% in the late group (95% CI 209 70.4, 77.8) to 30.0% (95% CI 18.4, 39.9) in the early group. It also declined significantly against ICU admission, dropping from 56.1% (95% CI 51.4, 60.2) to 29.9% (95% CI 13.9, 43.0). For deaths, however, CoronaVac′s effectiveness did not wane after three to five months of full vaccination. Vaccine effectiveness against COVID-19 infections waned after three to five months of full vaccination for both BNT162b2 and CoronaVac in Malaysia. Additionally, for CoronaVac, protection against ICU admission declined as well. Evidence on vaccine effectiveness over time informs evolving policy decisions on vaccination.
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<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.01.15.22269326v1" target="_blank">Waning COVID-19 Vaccine Effectiveness for BNT162b2 and CoronaVac in Malaysia: An Observational Study</a>
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<li><strong>Using Mobile Phone-based Text Message to Recruit Representative Samples: Assessment of a Cross-Sectional Survey about the COVID-19 Vaccine Hesitation.</strong> -
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Background: Limited research has examined mobile phone-based platforms for survey recruitment, especially during the COVID-19 pandemic in Brazil. Our objective was to investigate the feasibility and representativeness of mobile phone-based advertisement during a preliminary study about COVID-19 vaccine hesitation in Brazil. Moreover, we evaluate whether the older population can be reached through mobile phone-based platforms of the survey. Methods: We conducted a study in December 2021 based on a preliminary survey about the COVID-19 vaccine hesitation in Assis, Brazil, Sao Paulo state. From a list of the adult population hesitant for the second dose of the COVID-19 vaccine, we sent a mobile phone- based advertisement inviting the participants to answer the survey for one week. The respondent9s data were collected in a Google form platform. The comparison between the target population and the respondents was made using the Chi-squared test and the Welch9s test, using a P-value of .05 as significative. Results: The response rate was 9.99% after one week. The mean age of the respondent group was 33.97 (SD 14.99) and 35.05 (SD 14.19) of the population, with a P-value of .192 and a Cohen9s d coefficient of 0.0754, corresponding to a small effect size between groups. We demonstrate that the mobile phone-based survey is a feasible and representative strategy during the pandemics in Brazil. Moreover, the older population respondent was representative. Conclusion: We achieved a representative sample of respondents using the mobile phone-based survey in Brazil. Furthermore, it was representative in all sociodemographic and health characteristics assessed. Finally, these findings suggest the method is a highly feasible and economical means of recruiting for survey research.
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<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.01.15.22269259v1" target="_blank">Using Mobile Phone-based Text Message to Recruit Representative Samples: Assessment of a Cross-Sectional Survey about the COVID-19 Vaccine Hesitation.</a>
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<li><strong>Development of an effective immune response in adults with Down Syndrome after SARS-CoV-2 vaccination</strong> -
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Immune dysregulation in individuals with Down syndrome (DS) leads to an increased risk for hospitalization and death due to COVID-19 and may impair the generation of protective immunity after vaccine administration. The cellular and humoral responses of 55 DS patients who received a complete SARS-CoV-2 vaccination regime at one to three (V1) and six (V2) months were characterised. SARS-CoV-2-reactive CD4+ and CD8+ T lymphocytes with a predominant Th1 phenotype were observed at V1, and increased at V2. Likewise, a sustained increase of SARS-CoV-2-specific circulating Tfh (cTfh) cells was observed one to three months after vaccine administration. Specific IgG antibodies against SARS- CoV-2 S protein were detected in 96% and 98% of subjects at V1 and V2, respectively, though IgG titers decreased significantly between both timepoints.
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🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.01.14.22269303v1" target="_blank">Development of an effective immune response in adults with Down Syndrome after SARS-CoV-2 vaccination</a>
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<li><strong>Associations Between Physical Activity, Affect Regulation Difficulties, and Mental Health Among Canadian Adolescents at Two Different Points of the COVID-19 Pandemic</strong> -
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Although physical activity declined with social distancing measures and stay-at-home orders during the COVID-19 pandemic, youth who engaged in more physical activity experienced fewer mental health problems. If and how physical activity maintained its protective role throughout the ongoing pandemic remains unclear. This study models associations between three types of physical activity (indoor, outdoor, with parents), affect regulation, and anxious and depressive symptoms in two adolescent samples (W1: Summer 2020; W2: Winter 2020/21).
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🖺 Full Text HTML: <a href="https://psyarxiv.com/y2b4k/" target="_blank">Associations Between Physical Activity, Affect Regulation Difficulties, and Mental Health Among Canadian Adolescents at Two Different Points of the COVID-19 Pandemic</a>
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<li><strong>Resilient T cell responses to B.1.1.529 (Omicron) SARS-CoV-2 variant</strong> -
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Emergence of the SARS-CoV-2 variant-of-concern (VOC) B.1.1.529 (Omicron) in late 2021 has raised alarm among scientific and health care communities due to a surprisingly large number of mutations in its spike protein. Public health surveillance indicates that the Omicron variant is significantly more contagious than the previously dominant VOC, B.1.617.2 (Delta). Several early reports demonstrated that Omicron exhibits a higher degree (~10-30-fold) of escape from antibody neutralization compared to earlier lineage variants. Therefore, it is critical to determine how well the second line of adaptive immunity, T cell memory, performs against Omicron in people following COVID-19 infection and/or vaccination. To that purpose, we analyzed a cohort (n=345 subjects) of two- or three- dose messenger RNA (mRNA) vaccine recipients and COVID-19 post infection subjects (including those receiving 2 doses of mRNA vaccine after infection), recruited to the CDC-sponsored AZ HEROES research study, alongside 32 pre-pandemic control samples. We report that T cell responses against Omicron spike peptides were largely preserved in all cohorts with established immune memory. IFN-gamma producing T cell responses remained equivalent to the response against the ancestral strain (WA1/2020), with some (&lt;20%) loss in IL-2 single- or IL-2+IFN-gamma+ poly-functional responses. Three-dose vaccinated participants had similar responses to Omicron relative to convalescent or convalescent plus two-dose vaccinated groups and exhibited responses significantly higher than those receiving two mRNA vaccine doses. These results provide further evidence that a three-dose vaccine regimen benefits the induction of optimal functional T cell immune memory.
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🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.01.16.22269361v1" target="_blank">Resilient T cell responses to B.1.1.529 (Omicron) SARS-CoV-2 variant</a>
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<li><strong>A prospective, single-center study to evaluate the clinical performance of Meril ABFind in individuals vaccinated against COVID-19</strong> -
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Background: Accurate rapid antibody detection kits requiring minimum infrastructure are beneficial in detecting post-vaccination antibodies in large populations. ChAdOx1-nCOV (COVISHIELD) and BBV-152 (Covaxin) vaccines are primarily used in India. Methods: In this single-centre prospective study, performance of Meril ABFind was investigated by comparing with Abbott SARS-CoV-2 IgG II Quant (Abbott Quant), GenScript cPass SARS-CoV-2 neutralization antibody detection kit (GenScript cPass), and COVID Kawach MERILISA (MERILISA) in 62 vaccinated health care workers (HCW) and 40 pre-pandemic samples. Results: In the vaccinated subjects, Meril ABFind kit displayed high sensitivity of 93.3% (CI, 89.83%-96.77%), 94.92% (CI, 91.88%-97.96%), and 90.3% (CI, 86.20%-94.4%) in comparison to Abbott Quant, MERILISA, and GenScript cPass respectively. The results of the Meril ABFind in the COVISHIELD-vaccinated group were excellent with 100% sensitivity in comparison to the other three kits. In the Covaxin-vaccinated group, Meril ABFind displayed sensitivity ranging from 80% to 88.9%. In control samples, there were no false positives detected by Meril ABFind, while Abbott Quant, MERILISA, and GenScript cPass reported 2.5%, 10.0%, and 12.5% false positives, respectively. In the pre- pandemic controls, specificity of Meril ABFind was 100%, Abbott Quant 97.5%, MERILISA 90%, and GenScript cPass 87.5%. Conclusion: The Meril ABFind kit demonstrated satisfactory performance when compared with the three commercially available kits and was the only kit without false positives in the pre-pandemic samples. This makes it a viable option for rapid diagnosis of post vaccination antibodies.
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🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2022.01.15.22269231v1" target="_blank">A prospective, single- center study to evaluate the clinical performance of Meril ABFind in individuals vaccinated against COVID-19</a>
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<li><strong>On serendipity and innovations in public health</strong> -
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I briefly discuss about serendipity in the cases of penicillin discovery and Covid-19 vaccine research.
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🖺 Full Text HTML: <a href="https://osf.io/ey7k3/" target="_blank">On serendipity and innovations in public health</a>
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<li><strong>The impact of the COVID-19 pandemic on hospital services for patients with cardiac diseases: a scoping review</strong> -
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Background: The repercussions of the COVID-19 pandemic concern care in many clinical areas, including cardiology. We aim to assess the impact of the COVID-19 pandemic on hospital care for cardiac patients. Methods: Scoping review. Performance indicators were extracted and collated to inform on changes in the use of health services and care provided during January - June 2020. Results: Database searches yielded 6277 articles, of which 838 articles met the inclusion criteria during initial screening. After full-text screening, 94 articles were considered for data extraction. In total, 1637 indicators were retrieved, showing large variation in the indicators and their definitions. Most of the indicators that provided information on changes in number of admissions (n=118, 88%) signalled a decrease in admissions; 88% (n=15) of the indicators showed patients delayed presentation and 40% (n=54) showed patients in a worse clinical condition. A reduction in diagnostic and treatment procedures was signalled by 95% (n=18) and 81% (n=64) of the indicators reporting on cardiac procedures, respectively. Length of stay decreased in 58% (n=21) of the indicators and acute coronary syndromes treatment times increased in 61% (n=65) of the indicators. Outpatient activity decreased in 94% (n=17) of the indicators related with outpatient care, whereas telehealth utilization increased in 100% (n=6). Outcomes worsened in 40% (n=35) of the indicators, and mortality rates increased in 52% (n=31). Conclusion: All phases of the hospital cardiac care pathway were affected. This information could support the planning of care during the ongoing pandemic and in future events.
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<div class="article-link article-html- link">
🖺 Full Text HTML: <a href="https://www.medrxiv.org/content/10.1101/2021.12.01.21267100v2" target="_blank">The impact of the COVID-19 pandemic on hospital services for patients with cardiac diseases: a scoping review</a>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Can lifestyle factors be the key in deciding the COVID-19 outcome?</strong> -
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The COVID-19 recovery rate of 97.3% and the death per million of 345 in India are better than the corresponding values in the USA and most of Europe despite better health infrastructure in these countries. The mean COVID fatality rate of Europe and a few countries in America is seven times that of India. This warrants a systematic study of the factors behind this conspicuous disparity. It is time to study lifestyle and other factors that may be related to recovery with minimal medical intervention or serious complications, leading to belated recovery and sometimes mortality. Obesity and excessive consumption of soft drinks, red meat and processed food may have a role to play in the European and American countries. On the other hand, the use of turmeric, black pepper, ginger in daily cooking, consumption of Indian gooseberry, Tulasi, different decoctions (Kashaya) and practice of various immune-boosting breathing exercises including yoga might have had a role in India. A detailed study involving a sizable number of cases of recovery and death in India, USA and some European countries will throw light on these factors behind the significant differences. The results shall provide crucial learning to the world for managing future waves and pandemics.
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<div class="article-link article-html-link">
🖺 Full Text HTML: <a href="https://osf.io/qhupm/" target="_blank">Can lifestyle factors be the key in deciding the COVID-19 outcome?</a>
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<h1 data-aos="fade-right" id="from-clinical-trials">From Clinical Trials</h1>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Evaluation of Safety &amp; Efficacy of MIR 19 ® Inhalation Solution in Patients With Moderate COVID-19</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Drug: MIR 19 ®;   Combination Product: Standard COVID-19 therapy<br/><b>Sponsors</b>:   National Research Center - Institute of Immunology Federal Medical-Biological Agency of Russia;   St. Petersburg Research Institute of Vaccines and Sera<br/><b>Completed</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A Telemedicine Brief Mindfulness Intervention in Post-COVID-19</strong> - <b>Condition</b>:   Post COVID-19<br/><b>Intervention</b>:   Other: Mindfulness<br/><b>Sponsors</b>:  <br/>
Fondazione Don Carlo Gnocchi Onlus;   Catholic University of the Sacred Heart<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Immunogenicity and Safety of a Booster Dose of the SpikoGen COVID-19 Vaccine</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Biological: SARS-CoV-2 recombinant spike protein + Advax-SM adjuvant;   Biological: Saline placebo<br/><b>Sponsors</b>:   Cinnagen;   Vaxine Pty Ltd<br/><b>Active, not recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Plasma Exchange in Covid-19 Patients With Anti-interferon Autoantibodies</strong> - <b>Condition</b>:   COVID-19<br/><b>Intervention</b>:   Drug: Therapeutic plasma exchange<br/><b>Sponsor</b>:  <br/>
Centre Hospitalier St Anne<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Randomized Multicenter Study on the Efficacy and Safety of Favipiravir for Parenteral Administration Compared to Standard of Care in Hospitalized Patients With COVID-19</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Drug: Favipiravir;   Drug: Remdesivir<br/><b>Sponsors</b>:   Promomed, LLC;   Solyur Pharmaceuticals Group<br/><b>Completed</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Inhaled Heparin for Hospitalised Patients With Coronavirus Disease 2019 (COVID-19)</strong> - <b>Condition</b>:   COVID-19<br/><b>Intervention</b>:   Drug: unfractionated Heparin<br/><b>Sponsors</b>:  <br/>
Australian National University;   The George Institute;   St George Hospital, Australia;   St Vincent’s Hospital Melbourne;   John Hunter Hospital;   Royal North Shore Hospital<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>PTX-COVID19-B, an mRNA Humoral Vaccine, Intended for Prevention of COVID-19 in a General Population. This Study is Designed to Demonstrate the Safety, Tolerability, and Immunogenicity of PTX-COVID19-B in Comparison to the Pfizer- BioNTech COVID-19 Vaccine.</strong> - <b>Condition</b>:   Covid19 Vaccine<br/><b>Interventions</b>:   Biological: PTX-COVID19-B;   Biological: Pfizer- BioNTech COVID-19 vaccine;   Biological: Placebo<br/><b>Sponsor</b>:   Providence Therapeutics Holdings Inc.<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Immunogenicity and Safety Study of a SCB-2019 Vaccine Booster Dose to Adults Who Previously Received Primary Series of Selected COVID-19 Vaccines</strong> - <b>Condition</b>:   COVID-19<br/><b>Intervention</b>:   Biological: Candidate vaccine, SCB-2019<br/><b>Sponsor</b>:   Clover Biopharmaceuticals AUS Pty Ltd<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>COVID-19 Messaging for Vaccination</strong> - <b>Conditions</b>:   Vaccination Refusal;   COVID-19 Pandemic<br/><b>Interventions</b>:   Behavioral: Doctor Videos;   Behavioral: Sharing Videos;   Behavioral: Sharing Videos (Influencers);   Behavioral: Vaccine Ambassador;   Behavioral: Video framing;   Behavioral: Video order<br/><b>Sponsors</b>:   Massachusetts Institute of Technology;   Facebook, Inc.;   Code3;   Stanford University;   Harvard University;   Yale University;   Johns Hopkins University;   Massachusetts General Hospital;   Ludwig-Maximilians - University of Munich;   National Institutes of Health (NIH)<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>IMPACT OF THERAPEUTIC PLASMA EXCHANGE ON ACQUIRED VACCINAL ANTI-SARS-CoV-2 ANTIBODIES.</strong> - <b>Condition</b>:   COVID-19<br/><b>Intervention</b>:   Diagnostic Test: Evolution of antibodies titre<br/><b>Sponsor</b>:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Spa Rehabilitation, Antioxidant and Bioenergetic Supportive Treatment of Patients With Post-Covid-19 Syndrome</strong> - <b>Condition</b>:   COVID-19 Respiratory Infection<br/><b>Interventions</b>:   Dietary Supplement: ubiquinol (reduced coenzyme Q10);   Other: mountain spa rehabilitation;   Diagnostic Test: 2x14 ml of peripheral blood collected in a tube with anticoagulant<br/><b>Sponsors</b>:   Comenius University;   Sanatórium of Dr. Guhr, n.o.<br/><b>Completed</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Effect of Dietary Intervation on Endothelial Glycocalyx in COVID-19 Patients.</strong> - <b>Conditions</b>:   COVID-19;   Endothelial Dysfunction<br/><b>Interventions</b>:  <br/>
Dietary Supplement: Food supplement Endocalyx;   Dietary Supplement: Placebo<br/><b>Sponsor</b>:  <br/>
University of Athens<br/><b>Not yet recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Public Support for COVID-19 Test Allocation</strong> - <b>Conditions</b>:   Health Equity;   COVID-19<br/><b>Interventions</b>:   Behavioral: First Come, First Served;   Behavioral: Random;   Behavioral: Disadvantaged Priority &amp; Random<br/><b>Sponsor</b>:   University of Pennsylvania<br/><b>Completed</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Randomized Study of Efficacy of Different Treatment Regimens of Olokizumab</strong> - <b>Condition</b>:   COVID-19<br/><b>Interventions</b>:   Drug: Olokizumab;   Drug: Standard therapy<br/><b>Sponsors</b>:   R-Pharm;   Federal Budget Institution of Science “Central Research Institute of Epidemiology” of the Rospotrebnadzor;   Group of companies Medsi, JSС<br/><b>Recruiting</b></p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Study to Assess the Safety, Tolerability and Explore the Immunogenicity of EG-COVID in Healthy Adult Volunteers</strong> - <b>Condition</b>:   COVID-19 Vaccine<br/><b>Interventions</b>:   Drug: EG-COVID-003;   Drug: EG-COVID-001<br/><b>Sponsors</b>:   EyeGene Inc.;   Novotech (Australia) Pty Limited<br/><b>Not yet recruiting</b></p></li>
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<h1 data-aos="fade-right" id="from-pubmed">From PubMed</h1>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Impact of Warhead Modulations on the Covalent Inhibition of SARS-CoV-2 M(pro) Explored by QM/MM Simulations</strong> - The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus-2, SARS-CoV-2, shows the need for effective antiviral treatments. Here, we present a simulation study of the inhibition of the SARS-CoV-2 main protease (M^(pro)), a cysteine hydrolase essential for the life cycle of the virus. The free energy landscape for the mechanism of the inhibition process is explored by QM/MM umbrella sampling and free energy perturbation simulations at the M06-2X/MM level of theory for two…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Validation of a Saliva-Based Test for the Molecular Diagnosis of SARS-CoV-2 Infection</strong> - CONCLUSIONS: RT-PCR assays conducted on a stored saliva sample achieved similar performance to those on NP swabs, and this may provide a very effective tool for population screening and diagnosis. Collection of saliva in a stabilizing solution makes the test more convenient and widely available; furthermore, the denaturing properties of the solution reduce the infective risks belonging to sample manipulation.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Sustained generation of peroxide from the air by carbon nano onion under visible light to combat RNA virus</strong> - Carbon nano onion (CNO) from dried grass has been synthesized by carbonization in the size range, 20 to 100 nm. This shows catalytic property to transform aerial oxygen under visible light to generate reactive oxygen species (ROS). A concept has been presented herein to show that this CNO even under room light generates hydrogen peroxide which inhibits WSN influenza virus (H1N1). The advantage of introducing CNO, synthesized from a cheap source to cater to the global need, is to sterilize…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Local practices and production confer resilience to rural Pacific food systems during the COVID-19 pandemic</strong> - Resilience of food systems is key to ensuring food security through crisis. The COVID-19 pandemic presents an unprecedented shock that reveals varying levels of resilience of increasingly interconnected food systems across the globe. We contribute to the ongoing debate about whether increased connectivity reduces or enhances resilience in the context of rural Pacific food systems, while examining how communities have adapted to the global shocks associated with the pandemic to ensure food…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Potential of phytocompounds from Brassica oleracea targeting S2-domain of SARS-CoV-2 spike glycoproteins: Structural and molecular insights</strong> - By 24th Sep. 2021, there are more than 229 million COVID-19 cases worldwide, the researchers are tirelessly working to discover and develop an efficient drug molecule against this devastative viral infection. This study aims to evaluate the inhibitory efficiency of the organic acids and phenolic compounds present in Brassica oleracea (Tronchuda Cabbage) against spike glycoprotein in SARS-CoV-2. Thirty-seven phytocompounds are screened on the basis of their molecular weight (&lt;500 g/mol) and 14…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Naturally occurring anthraquinones as potential inhibitors of SARS-CoV-2 main protease: an integrated computational study</strong> - The novel coronavirus disease (COVID-19) has spread throughout the globe, affecting millions of people. The World Health Organization (WHO) has declared this infectious disease a pandemic. At present, several clinical trials are going on to identify possible drugs for treating this infection. SARS-CoV-2 M^(pro) is one of the most critical drug targets for the blockage of viral replication. The aim of this study was to identify potential natural anthraquinones that could bind to the active site…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Xuanfei Baidu Decoction reduces acute lung injury by regulating infiltration of neutrophils and macrophages via PD-1/IL17A pathway</strong> - The pathogenic hyper-inflammatory response has been revealed as the major cause of the severity and death of the Corona Virus Disease 2019 (COVID-19). Xuanfei Baidu Decoction (XFBD) as one of the “three medicines and three prescriptions” for the clinically effective treatment of COVID-19 in China, shows unique advantages in the control of symptomatic transition from moderate to severe disease states. However, the roles of XFBD to against hyper-inflammatory response and its mechanism remain…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>K63 ubiquitination in immune signaling</strong> - Ubc13-catalyzed K63 ubiquitination is a major control point for immune signaling. Recent evidence has shown that the control of multiple immune functions, including chronic inflammation, pathogen responses, lymphocyte activation, and regulatory signaling, is altered by K63 ubiquitination. In this review, we detail the novel cellular sensors that are dependent on K63 ubiquitination for their function in the immune signaling network. Many pathogens, including severe acute respiratory syndrome…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle</strong> - The advent and persistence of the Severe Acute Respiratory Syndrome Coronavirus - 2 (SARS-CoV-2)-induced Coronavirus Disease (COVID-19) pandemic since December 2019 has created the largest public health emergency in over a century. Despite the administration of multiple vaccines across the globe, there continues to be a lack of approved efficacious non-prophylactic interventions for the disease. Flavonoids are a class of phytochemicals with historically established antiviral, anti-inflammatory…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Inhibition of RNA Viruses by Amaryllidaceae Alkaloids: Opportunities for the Development of Broad-Spectrum Anti- Coronavirus Drugs</strong> - The global COVID-19 pandemic has claimed the lives of millions and disrupted nearly every aspect of human society. Currently, vaccines remain the only widely available medical means to address the cause of the pandemic, the SARS-CoV-2 virus. Unfortunately, current scientific consensus deems the emergence of vaccine-resistant SARS-CoV-2 variants highly likely. In this context, the design and development of broad-spectrum, small-molecule based antiviral drugs has been described as a potentially…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Comparative investigation of toxicity induced by UV-A and UV-C radiation using Allium test</strong> - Organisms are increasingly exposed to ultraviolet (UV) rays of sunlight, due to the thinning of the ozone layer and its widespread use in sterilization processes, especially against the SARS-CoV-2 virus. The present study was conducted with the purpose of evaluating the damages of UV-A and UV-C radiations in Allium cepa L. roots. The effects of two different types of UV on some physiological, biochemical, cytogenotoxic, and anatomical parameters were investigated in a multifaceted study. Three…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Clinical Application of Antibody Immunity Against SARS-CoV-2: Comprehensive Review on Immunoassay and Immunotherapy</strong> - The current COVID-19 global pandemic poses immense challenges to global health, largely due to the difficulty to detect infection in the early stages of the disease, as well as the current lack of effective antiviral therapy. Research and understanding of the human immune system can provide important theoretical and technical support for the clinical diagnosis and treatment of COVID-19, the clinical implementations of which include immunoassays and immunotherapy, which play a crucial role in the…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The anti-C5a antibody vilobelimab efficiently inhibits C5a in patients with severe COVID-19</strong> - Recently, we reported the phase II portion of the adaptive phase II/III PANAMO trial exploring potential benefit and safety of selectively blocking C5a with the monoclonal antibody vilobelimab (IFX-1) in patients with severe coronavirus disease 2019 (COVID-19). The potent anaphylatoxin C5a attracts neutrophils and monocytes to the infection site, causes tissue damage by oxidative radical formation and enzyme releases, and leads to activation of the coagulation system. Results demonstrated that…</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Synthesis of low-molecular weight fucoidan derivatives and their binding abilities to SARS-CoV-2 spike proteins</strong> - Fucoidan derivatives 10-13, whose basic sugar chains are composed of repeating α(1,4)-linked l-fucopyranosyl residues with different sulfation patterns, were designed and systematically synthesized. A structure-activity relationship (SAR) study examined competitive inhibition by thirteen fucoidan derivatives against heparin binding to the SARS-CoV-2 spike</li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">protein. The results showed for the first time that 10 exhibited the highest inhibitory activity of the fucoidan derivatives used. The…</li>
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<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2</strong> - SARS-CoV-2 infection of human cells is initiated by the binding of the viral Spike protein to its cell-surface receptor ACE2. We conducted a targeted CRISPRi screen to uncover druggable pathways controlling Spike protein binding to human cells. Here we show that the protein BRD2 is required for ACE2 transcription in human lung epithelial cells and cardiomyocytes, and BRD2 inhibitors currently evaluated in clinical trials potently block endogenous ACE2 expression and SARS-CoV-2 infection of human…</li>
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<h1 data-aos="fade-right" id="from-patent-search">From Patent Search</h1>
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<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>IDENTIFICATION AND ALARM SYSTEM FOR FACIAL CORONA MASK USING CNN BASED IMAGE PROCESSING</strong> - tThe covid-19 epidemic is the world’s largest wake-up call for people to pay attention to their own and society’s health. One thing to keep in mind is that there is a segment of the population that has been exposed to the covid-19 virus and has generated antibodies without developing any significant illnesses and is continuing to be healthy. This indicates that a significant section of the population, even excluding the elderly, lacks the necessary bodily immunity to combat a Viral infection. As terrible as covid-19 is on a global scale, developing personal health standards and preventative measures for any pathogenic virus as a community would have spared many lives. In’this work, a camera is combined with an image processing system to recognise facial masks, which may be improved in a variety of ways. First and foremost, this method is meant to identify masks on a single person’s face. While this method is efficient in identifying someone has a mask, it does not ensure that they will wear it all of the time. The most effective update for this task is to install a camera with a wide field of view so that many individuals can be seen in the frame, and the faces of those who aren’t wearing markings can be identified, as well as the number of people and the timing. - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=IN346889253">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>ANTIMICROBIAL SANITIZING FORMULATION</strong> - An antimicrobial sanitizing formulation, comprising, i) isopropyl alcohol in the range of 0.1%- 80% w/w, ii) an emollient in the range of 0.1%-15% w/w, iii) hydrogen peroxide in the range of 0.1 0.13% w/w, iv) citric acid in the range of 0.1% to 2.0% w/w, v) silver nitrate in the range of 0.1% to 0.5% w/w, and vi) a fragrance imparting agent in the range of 0.1% to 2.0% w/w. - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=IN346888094">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A HEALTH BAND WITH A BIOMETRIC MODULE AND WORKING METHOD THEREOF</strong> - The present invention discloses a health band with a biometric module and method thereof. The assembly includes, but not limited to, a plurality of sensors configured to gather health data associated with a predefined symptom of a medical condition of a user; a memory unit configured to store the data and an interface, which is configured to determine the medical condition using the data;a processing unit configured to execute the application; and a notification facility configured to provide a notification upon receiving from the interface an instruction associated with the notification, wherein the notification is associated with a drug reminder and the like. - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=IN346889061">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>RNA 검출 방법</strong> - 본 발명은 RNA의 분석 및 검출 방법에 관한 것이다. 특히, 본 발명은 특히, 본 발명은 짧은 염기서열의 RNA까지 분석이 가능하면서도 높은 민감도 및 정확도로 정량적 검출까지 가능하여 감염증, 암 등 여러 질환의 진단 용도로도 널리 활용될 수 있다. - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=KR346026620">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>REUNION OF PHOTOTHERMAL THERAPY WITH MXENE ADSORBED UREMIC TOXINS AND CYTOKINES: A SHILED FOR COVID-19 PATENTS</strong> - The COVID-19 pandemic has created havoc throughout the world. The disease has proved to be more fatalfor patients having comorbidities like diabetics, lungs and kidney infections, etc. In the case of COVID-19 patientsI having kidney injury, the. removal of uremic toxins from the blood is hindered and there is a rapid surge in the levelj of cytokine hormone resulting in the death of the patient in a short interval of time. To resolve this issue,iI; researchers have examined that the immediate removal of these toxins can improve the condition of the patient to a |greater extent. Studies have also found the presence of SARS CoV-2 viral RNAs in the blood of COVID-19patients, which risks their life as well as impacts the blood transfusion process, especially in the case ofasymptomatic patients. Hence it is required to control the surge of cytokines and uremic toxins as well as disinfectthe blood of the patient from the virus. MXenes, having a foam-like porous structure and hydrophilic negativesurface functionalization have greater adsorption efficiency as well as superior photothermal activity. Utilizingthese properties of MXenes, the MXene membranes can be used in the dialyzer that can help in the efficient andBiuick removal of the uremic toxins, cytokines, and other impurities from the blood. Along with this the greaterTJAdsorption efficiency of MXenes to amino acids result in the trapping of the SARS CoV-2 viruses on the surface J)3&gt;f the MXene. Many researchers as well as the WHO have proved the efficient reduction of the viral copy numbersjjvith the increase of temperature. Hence, followed by the trapping of the viruses, the implementation of"Zphotothermal Therapy can result in the inactivation and denaturation of the viruses and their respective viral RNAsBJlby the produced heat. The same process can be repeated several times to get better results. This whole process canr&gt;oQ-esult in impurity-free and infection-free blood, that can be returned back to the body of the patient or can be!— I Sitilized for the blood transfusion process without any risk of infection.IM - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=IN346889224">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>REDUCING AND STOPPING OXYGEN WASTAGE IN HOSPITAL</strong> - In an aspect, the present invention discloses a system (200) for prevention and reduction of oxygen wastage from oxygen mask (202). The system (200) includes the oxygen mask (202) having straps; a tension sensor (204), the tension sensor being sensitive towards tension produced in the straps as the oxygen gets leakage through sides of the mask (202); a processor configured in alignment with the tension sensor (204); and a buzzer (206) in alignment with processor. - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=IN346042219">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Hung Thanh Phan COVID-19 NEW SOLUTION</strong> - - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=AU344983394">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>A METHOD TO REVEAL MOTIF PATTERNS OF COVID-19 USING MULTIPLE SEQUENCE ALIGNMENT</strong> - This present invention consists of different levels of computation and work in a pipeline manner i.e., input of one will be output of another and it is sequential process. Input data given in form of nucleotide sequence (DNA) of different COVID-19 patients (1). Using these nucleotide sequence perform mutation if possible and arrange them in a sequential order (2). Arrange number of nucleotide sequences of different patients in row wise and also compute number of characters in each row. (3). Compute frequency of occurrence of character in column wise and create a matrix having 4 rows and maximum sequence length will be the column size (4). Find the character like A, T, C, and G which one has maximum score and similarly find for each column to produce a final sequence (5). - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=IN346039750">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>REUSABILITY OF ANTIMICROBIAL MULTILAYER NANOFIBER MASK WITH HIGH PROTECTIVE</strong> - According to the present Invention, an antimicrobial multi-layer protective mask has a body section including at least first and second fabric layers having random fiber configuration; a middle layer including nanofiber membrane; and third and fourth fabric layers. There are two layers of fabric sandwiched between the nanofiber membrane and the third fabric layer. Fabric layers 1 through 4 each include a synergistic mixture of at least two metal oxide powders that exhibit synergistic antibacterial capabilities, such as the first metal’s mixed-oxidation state oxide and a second metal’s single-oxidation-state oxide. - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=IN346039053">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>用于检测新型冠状病毒的引物、探针及其应用</strong> - 本发明属于医学检测领域，具体涉及用于检测新型冠状病毒的引物、探针及其应用。本发明设计了四组引物探针，采用常用的TaqMan‑MGB探针法对新型冠状病毒进行检测，可用于检测新型冠状病毒野生型、新型冠状病毒变异株、新型冠状病毒B.1.617亚型变异株以及新型冠状病毒B.1.617.2亚型变异株。假病毒测试结果表明，试剂灵敏度可达到500copies/mL。10份健康志愿者和4份常见其他呼吸道病原体检测均没有非特异性扩增，引物探针组合及试剂特异性较好。 - <a href="https://patentscope.wipo.int/search/en/detail.jsf?docId=CN346990286">link</a></p></li>
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<h1 data-aos="fade-down" id="daily-dose">Daily-Dose</h1>
<h1 data-aos="fade-right" data-aos-anchor-placement="top-bottom" id="contents">Contents</h1>
<ul>
<li><a href="#from-new-yorker">From New Yorker</a></li>
<li><a href="#from-vox">From Vox</a></li>
<li><a href="#from-the-hindu-sports">From The Hindu: Sports</a></li>
<li><a href="#from-the-hindu-national-news">From The Hindu: National News</a></li>
<li><a href="#from-bbc-europe">From BBC: Europe</a></li>
<li><a href="#from-ars-technica">From Ars Technica</a></li>
<li><a href="#from-jokes-subreddit">From Jokes Subreddit</a></li>
</ul>
<h1 data-aos="fade-right" id="from-new-yorker">From New Yorker</h1>
<ul>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Prince Andrew’s Very Bad Week</strong> - A ruling in a New York legal case, in which Andrew is accused of sexual abuse, led to the Duke of York being stripped of his military titles. - <a href="https://www.newyorker.com/news/letter-from-the-uk/prince-andrews-very-bad-week">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Supreme Court’s Vexing Mixed Message on Vaccine Mandates</strong> - Two rulings reveal just how hard-conservative the core of the Court is. - <a href="https://www.newyorker.com/news/daily-comment/the-supreme-courts-vexing-mixed-message-on-vaccine-mandates">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Latinx Community and COVID-Disinformation Campaigns</strong> - Researchers debate how best to counter false narratives—and racial stereotypes. - <a href="https://www.newyorker.com/news/daily-comment/the-latinx-community-and-covid-disinformation-campaigns">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Sunday Reading: Honoring Martin Luther King, Jr.</strong> - From the magazine’s archive: a selection of pieces about the significance of Dr. King’s extraordinary work and devotion to principle. - <a href="https://www.newyorker.com/books/double-take/sunday-reading-honoring-martin-luther-king-jr">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The Rival Shows of “Yellowjackets”</strong> - On watching girls—and genres—devour one another. - <a href="https://www.newyorker.com/culture/on-television/the-rival-shows-of-yellowjackets">link</a></p></li>
</ul>
<h1 data-aos="fade-right" id="from-vox">From Vox</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>TV’s buzziest shows aren’t trying to trick viewers anymore</strong> -
<figure>
<img alt="Melanie Lynskey stars in Yellowjackets, Jeremy Strong stars in Succession, Himesh Patel stars
in Station Eleven, and Kevin Costner stars in Yellowstone." src="https://cdn.vox-
cdn.com/thumbor/WawMNuzPcULvTSMHtGdGz10bOTg=/134x0:1734x1200/1310x983/cdn.vox-
cdn.com/uploads/chorus_image/image/70399316/headshots_1642195275626.0.jpg"/></figure></li>
</ul>
<figcaption>
<em>Yellowjackets</em>, <em>Succession</em>, <em>Station Eleven</em>, and <em>Yellowstone</em> have all skewed away from the mystery box in their storytelling. | Showtime/HBO/HBO Max/Paramount
</figcaption>
<pre><code>&lt;/figure&gt;</code></pre>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Succession, Yellowjackets, and other critically acclaimed shows are leaving the mystery box behind. That’s a good thing.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xvckw0">
Somewhere in the middle of “Doomcoming,” the penultimate episode of <a href="https://www.vox.com/culture/22868432/yellowjackets-pretty-little-liars-teen-girl-horror"><em>Yellowjackets</em>’ first season</a>, I had the pleasantly discombobulating feeling of realizing I wasn’t watching the TV show I thought I was.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="FnCYih">
The buzzy (haha) Showtime series about a soccer team of teenage girls struggling to survive in the wilderness, contrasted with their adult selves 25 years later, has drawn comparisons to <em>Lost</em> from many, <a href="https://www.vox.com/culture/22771675/yellowjackets-review-pilot-recap-showtime-crash-cannibals">including me</a>. Both shows, after all, feature dueling timelines, an eerie wilderness that might be supernatural in nature, and a plane crash.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ztpfRf">
I also drew <em>Lost</em> comparisons, though, because I thought <em>Yellowjackets</em> was what is typically known as a mystery-box show. On a mystery-box show, big questions unfurl into smaller questions, which unfurl into even smaller questions, which often loop back to the bigger questions. Ideally, those questions lead into each other. For instance, on <em>Lost</em>, the question of, “What’s in this mysterious hatch we found on the island?” had an answer (“some guy named Desmond”) that led into a host of other questions. (“Who does he work for?” “How did he wind up on the Island?” “How do the people he works for know about the island?”)
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jJkkWJ">
And <em>Yellowjackets</em> certainly has elements of the mystery-box show in its DNA. Core to the show is the question of how its main characters escaped the wilderness to begin with. Since we’re also seeing those characters as adults, we know they escaped after 19 months in the middle of nowhere and that the show will inevitably have to explain how that happened. But crucially, this is a question the audience<em> </em>has that the characters don’t. The adult versions of these women know how they got home. We’re the ones who don’t.
</p>
<aside id="X54POO">
<div>
</div>
</aside>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="3sCmTQ">
The longer you watch <em>Yellowjackets</em>, the more you realize that’s true of most of its mysteries. A character in the show usually knows the answer, and even if we don’t, what happened to them is informing how they act. Almost all of the mysteries established by the show’s pilot, mysteries I thought would last for several seasons, are largely answered by the end of the first season.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="wcm6hZ">
Who was the mysterious Antler Queen, the head of the cannibal society briefly teased in the show’s pilot? At the end of the finale, we more or less know. What happened to team captain Jackie out in the woods? We know that too. Could the show swerve away from these reveals? Sure. But why would it? Dealing with what happened next is so much more compelling than trying to somehow outsmart an audience that is literally crowdsourcing answers to your mysteries on Twitter and Reddit.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="mBNRmU">
It’s a different rhythm than TV fans are currently used to, but it’s part of a larger trend within TV drama at the moment, one where living with the implications of an answer bears richer drama than wrestling with the thorniness of a question.
</p>
<h3 id="Ptibpd">
Even if more shows are tamping down on their mystery-box qualities, we’re still discussing them like they’re keeping huge secrets
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="gq6U0z">
As an example of <em>Yellowjackets</em>’ interest in subverting your mystery- box expectations, look at a mystery within the show that turned out to be exactly what it seemed to be. Early in the season, the adult Shauna (one of the crash survivors, played by Melanie Lynskey) rear-ends a hot guy named Adam (Peter Gadiot). The two spark with each other and start sleeping together. But who is Adam?
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="rTVHdL">
The obvious answer here is: Adam is a man Shauna just happened to be in a car accident with. Because she’s the one who rear-ended him, rather than the other way around, it would strain credulity for him to be anything other than who he says he is. But the series’ fandom spent much of the season <a href="https://www.reddit.com/r/Yellowjackets/comments/rromzz/who_is_adam/">obsessing over who Adam might be</a>. Was he one of the other crash survivors? Was he working on a scam to get Shauna to tell all? Was he (my favorite goofy theory) a trans man who was also Shauna’s former best friend?
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="IzW26N">
The show did lean in the general direction of the speculation about Adam’s identity. Shauna’s daughter (who learned of her mother’s affair) was unable to find an online presence for the guy, which felt suspicious considering he was an artist, and Shauna caught him in a lie about his past.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="EaRLbl">
But in the end, Adam was … some guy Shauna rear-ended whom she sparked with. The show got its audience to so successfully internalize Shauna’s paranoia, driven by her past, that it became easy to miss how unlikely it was that he would be anybody but who he said he was.
</p>
<figure class="e-image">
<img alt="Shauna
stands in her kitchen, talking on the phone." src="https://cdn.vox-cdn.com/thumbor/sKNf-
DPAaPQ0Tn8eBhFdlPHNDok=/800x0/filters:no_upscale()/cdn.vox-
cdn.com/uploads/chorus_asset/file/23006459/Yellowjackets_102_0446_R__1_.jpg"/> <cite>Kailey Schwerman/Showtime</cite>
<figcaption>
Shauna made a new friend, and maybe he had a secret identity?? (He didn’t.)
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="HmltCj">
The rise of TV discussion online closely paralleled the rise of the mystery-box show. One of the earliest shows to inspire wide conversation and debate online was <em>The X-Files</em>, which ran (in its initial incarnation) from 1993 to 2002. That show’s massive alien conspiracy plotline all but begged audience members to sit down and try to connect the dots among its many elements.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="qIELwM">
And the ultimate resolution of that conspiracy led to a common pattern for mystery-box shows: If you really want to do the work, you can figure out exactly what the conspiracy was up to, but it’s so complicated and obscured that you’re unlikely to do the work. I’ve watched <em>The X-Files</em> many times (<a href="https://bookshop.org/books/monsters-of-the-week-the-
complete-critical-companion-to-the-x-files/9781419738036">I literally wrote a book on it</a>), and I can more or less tell you what the conspiracy was up to. But if I did this, I guarantee you your eyes would glaze over. It’s so needlessly complicated that you’ll simply bounce off it at some point.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="cIVggr">
But <em>The X-Files</em>’ popularity on the internet established a rough pattern for how we talk about TV online: We try to guess what the show is up to, even if the show isn’t being particularly unclear. And the closer that show gets to fantasy, sci-fi, or horror, the more we’ll keep trying to guess. <em>Yellowjackets</em>, as a horror show where certain elements are kept hidden from the audience, knows exactly what TV traditions it’s playing in. It uses those traditions to subvert our expectations in interesting ways.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="uvnJ7L">
An alien conspiracy isn’t a prerequisite for this kind of argument, though; even series grounded in reality attract this kind of thinking. <em>Succession</em>, for instance, has proved across three seasons that it doesn’t do big twists or surprising reveals, yet it continues to be talked about as though it does. Time after time, the show will present something that is more or less straightforward on a storytelling level, but its audience will argue about it endlessly, as though some big reveal is right around the corner. It’s what we’ve been trained to do, and <em>Succession</em> knows that.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="7cHvqX">
The mystery-box tradition is simply a heightened version of something in TV discussion that predates the internet. The secret sauce of a big and buzzy TV show since the late 1970s has often been giving the audience something to speculate and argue about from week to week, and internet discussion turns that up to a fever pitch. If <em>Dallas</em>’s famed “Who shot J.R.?” mystery from 1980 had aired in 2022, we would have worked ourselves into a collective tizzy on Twitter arguing over it.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="cG1Z8n">
But with this much online speculation, these mysteries are inevitably solved by the audience before the show can reveal what’s up. So when <em>Yellowstone</em> season three ended with most of the major characters in peril, season four started by revealing across its first two episodes that, nah, everybody was fine without a ton of unnecessary drama. Audiences already knew to expect that, because <em>Yellowstone</em> is not a show that kills off major characters (it’s had ample opportunity to do so and has never taken the bait), but the show seemed to almost deliberately subvert expectations anyway.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="tOgu6E">
Streaming shows that drop all at once can sometimes get away with leaning into the mystery box of it all, but even there, things are changing slowly but surely. The first season of Netflix’s <em>The Witcher</em> offered up a complicated tripartite timeline that viewers had to puzzle out, but its second season was much more straightforward. Granted, that series is based on books, and the second season seemed to inspire a lot less online chatter than the first, but it still played into this larger trend.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="9hh1QH">
Similarly, HBO Max’s <em>Station Eleven</em> (also based on a book) teased out several things that felt like mysteries but which had mostly clear answers that audiences could figure out ahead of time. The drama didn’t come from the answers being provided but from watching the characters wrestle with what those answers meant for their lives. A lesser show would have kept the secret history of the show’s main villain from the audience until the end of the season. <em>Station Eleven</em> told us pretty much right after we met him.
</p>
<h3 id="j2d9Mm">
Why the mystery-box show rings false in 2022
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="fr7h0l">
As audiences in 2022, we’re burnt out on the mystery box. Too many shows with mystery-box elements ended up with the<em> X-Files </em>problem: The amount of dedication you had to have to unpeel all of their elements was simply too heavy a lift for many viewers. I love <em>Lost</em>’s finale and its gutsy choice to accept that any answer to “What is this mysterious island?” was bound to disappoint. But I understand why many found that enervating.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="EhrGbv">
What’s more, we live in a reality where too many people try to turn the world into an elaborate conspiracy-driven hellhole, where everybody is trying to keep the truth from you and the villains are hidden in shadow. And that mentality cuts against something we know to be true, which is mostly that the villains are right out there in the open. Conspiracy theories in the real world have too often become a coping mechanism for those who feel powerless in the face of problems that seem insurmountable. If the truth is hidden in shadow, that’s an easier reality to approach than one where you know the truth but can’t do anything about it.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="mosp6s">
When I wrote my <em>X-Files</em> book (<a href="https://bookshop.org/books/monsters-of-the-week-the-complete-critical-companion-to-the-x-files/9781419738036">yes I’m going to link to it again</a>), creator Chris Carter was most obviously troubled in my interviews with him by the show’s legacy as ground zero for a lot of conspiratorial thinking in the American subconscious. <em>The X-Files</em> laundered conspiracy theories in some ways. It made them sexy and fun, and it pushed them into the mainstream. That choice was great for storytelling in the 1990s, but when the show came back for two revival seasons in the 2010s, it spent a lot of time worrying about figures like Alex Jones and Donald Trump, whose conspiratorial ramblings didn’t sound all that dissimilar from various <em>X-Files</em> characters.
</p>
<figure class="e-image">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><img alt="David
Duchovny on The X-Files." src="https://cdn.vox-cdn.com/thumbor/uI2tTAD031VKQPAjZkZa-
PwOnIQ=/800x0/filters:no_upscale()/cdn.vox-cdn.com/uploads/chorus_asset/file/6008099/XF_sc8_0058_hires1.jpg"/></p>
<cite>Fox</cite>
<figcaption>
Fox Mulder was a very popular TV character who believed in some pretty bonkers conspiracy theories.
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ESCdDi">
So what’s the other option here? Well, the other option is a show where what’s happening is clear and where the show tells you, multiple times, what’s up, and then the most obvious answer is the one that ultimately pays off. Sometimes, the hunk you rear-end with your car is just a hot guy, not part of a massive conspiracy.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="zAJOUI">
I was struck by this recent quote from <em>Station Eleven</em> showrunner <a href="https://www.rollingstone.com/tv/tv-features/station-eleven-finale-interview-1279145/">Patrick Somerville’s interview</a> with Rolling Stone’s Alan Sepinwall. In it, Somerville recounts a piece of advice he got from Damon Lindelof, who happens to be the co-creator of famed mystery-box show <em>Lost</em>.
</p>
<blockquote>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="RyUSr1">
People don’t want twists. What they want is to be told four times that it’s coming, and then for it to come. Because then different kinds of watchers are prepped. Some people can get out ahead of it and know it’s coming. Some are still surprised, but subconsciously, it’s a warmer embrace of a turn. It’s not quite a surprise, but it’s a hope that you are falling towards, just like water over a waterfall.
</p>
</blockquote>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="VoXbRs">
Not every show has you falling toward hope. <em>Succession</em> has you falling toward the inevitability of destruction, while <em>Yellowstone</em> has you falling toward the inevitability of the status quo. And <em>Yellowjackets</em> keeps you plummeting toward the terrifying dread of those girls in the woods starting to cannibalize each other. All of these shows tell you where they’re going, again and again, and dare you to say otherwise.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="mJWQ7l">
The problems we have to face in 2022 are not hidden from us, and the people keeping us from fixing them aren’t either. Income inequality continues to spiral out of control, and Covid-19 exposed endless faults in various governmental structures the world over. America is gripped by political dysfunction. And I don’t know if you’ve heard, but the climate is kind of a mess right now.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="MRdJPq">
To pretend that we don’t know what needs fixing is to willfully ignore what we know about the world. The shadows mostly hide faces and problems we already know well. Maybe that’s why so many of our best TV shows right now feature something we know is just around the corner. We’re powerless to stop it from coming, but we’re not yet powerless to stop it entirely.
</p>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Could a 54-year-old civil rights law be revived?</strong> -
<figure>
<img alt="" src="https://cdn.vox-
cdn.com/thumbor/GAHiJJRJzSEereRt9ilQLAAnLk0=/0x0:6912x5184/1310x983/cdn.vox-
cdn.com/uploads/chorus_image/image/70399261/GettyImages_1237720415.0.jpg"/>
<figcaption>
The Stone of Hope, a granite statue of civil rights leader Martin Luther King Jr., stands at his memorial in Washington, DC, on January 14,</figcaption></figure></li>
</ul>
<ol start="2022" type="1">
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">| Mandel Ngan/Getty Images
<pre><code>&lt;/figure&gt;</code></pre></li>
</ol>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Decades after Martin Luther King Jr.’s fight, American cities still segregate communities by race and class.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="2p9JZ0">
Rev. Martin Luther King Jr.’s assassination on April 4, 1968, helped usher in the passage of the Fair Housing Act (FHA), a law that promised to not only stop unjust discrimination but also reverse decades of government-created segregation.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="58QMY5">
The FHA, which made discrimination on the basis of race, color, national origin, religion, sex, familial status, and disability illegal in the process of buying and selling homes, had already failed to pass Congress in two earlier versions. As Michelle Adams <a href="https://www.newyorker.com/news/news-desk/the-unfulfilled-promise-of-the-fair-housing-act">wrote for the New Yorker</a><em>,</em> the 1968 version would likely have met the same end if not for the political impact of the assassination.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jHTF8K">
But just a few months after the act’s passage, Richard Nixon was elected, and,<strong> </strong>as Nikole Hannah-Jones explained, <a href="https://www.propublica.org/article/living-apart-how-
the-government-betrayed-a-landmark-civil-rights-law">the federal government’s “betrayal”</a> of the FHA’s promise began. Nixon’s Department of Housing and Urban Development Secretary George Romney did<strong> </strong>attempt to use the FHA to meet its goal and<strong> </strong>actually desegregate white communities, telling “HUD officials to <a href="https://www.propublica.org/article/living-apart-how-the-government-betrayed-a-landmark-civil-rights-law">reject applications</a> for water, sewer, and highway projects from cities and states where local policies fostered segregated housing.” But<strong> </strong>Nixon put a quick stop to this policy. And as Hannah-Jones documents, he wasn’t the last; since then, “a succession of presidents — Democrat and Republican alike — followed Nixon’s lead.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="aGVjJz">
In the 21st century, segregated communities are kept that way not through laws that explicitly attempt to keep certain areas white but through a more insidious method — <a href="https://www.youtube.com/watch?v=0Flsg_mzG-M">exclusionary zoning and land-use regulations</a> that make it illegal to build affordable types of housing, laws that allow wealthy Americans to <a href="https://www.vox.com/22534714/rail-roads-infrastructure-costs-america">block things from being built</a>, and a failure to consistently use <a href="https://www.vox.com/22252625/america-racist-housing-rules-how-to-
fix">federal civil rights laws to desegregate</a>.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="bf3Qi6">
All of this has resulted in the <a href="https://www.vox.com/22264268/covid-19-housing-insecurity-housing-prices-mortgage-rates-pandemic-zoning-supply-
demand">prices of housing and rent skyrocketing</a>. Over the last year, diminished supply as a result of these laws has pushed the <a href="https://www.vox.com/22264268/covid-19-housing-insecurity-housing-prices-mortgage-rates-pandemic-
zoning-supply-demand">cost of shelter</a> higher than ever, straining the pockets of working-class, middle-class, and even some high-income Americans.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ETeuXD">
To attack these regulations with the FHA, plaintiffs would have to prove that these laws have a “disparate impact” on a protected group — for instance, proving that a community <a href="https://www.relmanlaw.com/media/cases/23_10_CoxsackieComplaint-Filed%20_2_.pdf">blocking 300 units of moderately priced housing</a> was discriminating on race, national origin, or family status.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="TkYVTV">
But Richard Kahlenberg, a senior fellow at the Century Foundation and a leading thinker on economic integration, has an idea: Amend the Fair Housing Act to include economic discrimination as a legally prohibited form of discrimination.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="amGRHY">
No longer would litigators have to jump through hoops to prove that banning new affordable housing construction hurts people of color disproportionately. Instead, plaintiffs would just have to show that towns that blocked these developments were discriminating against poor people — regardless of their race, national origin, or family status.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="kCKb6z">
“It’s immoral for governments to erect barriers that exclude and discriminate based on income and, as a matter of basic human dignity, economic discrimination belongs in the Fair Housing Act,” Kahlenberg explained.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="vgrohC">
While Democrats have often talked eloquently about the importance of fair housing, they have never seriously attempted to take on exclusionary zoning at the federal level. Left in limbo is George Romney’s idea that the federal government should <a href="https://www.vox.com/2021/11/11/22774773/inflation-housing-market-home-
prices-biden-build-back-better">withhold funds</a> from localities still actively engaged in exclusionary zoning practices and thereby <a href="https://www.econlib.org/a-correction-on-housing-regulation/">undermining the economic wellbeing</a> of the entire country. Even now, as billions of infrastructure dollars are heading to states and local governments, it’s barely up for discussion.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="BgTkn2">
(Perhaps it has something to do with the fact that economically segregationist communities are often ones led by Democrats — in wealthy cities and suburbs, economic discrimination is a normal facet of life.)
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="N9Azjp">
Enacting an Economic Fair Housing Act wouldn’t be as sweeping as Romney’s idea from the 1970s, and any new protections would still need to be enforced. Kahlenberg has been advising Rep. Emanuel Cleaver (D-MO) as the latter has begun drafting a bill to amend the FHA to include economic discrimination in the housing market.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="J1rmwA">
“I think one of the greatest tributes that we can make to Dr.  King’s legacy is for us, this year, to pass an Economic Fair Housing Act,” Cleaver told me over the phone.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="NGBOP4">
I spoke with Kahlenberg about the potential for an Economic Fair Housing Act and whether this would really push the ball on increasing affordable housing. Our conversation has been edited for length and clarity.
</p>
<h4 id="CFvdok">
Jerusalem Demsas
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="OYJ0yq">
You’ve <a href="https://www.nytimes.com/2021/04/19/opinion/biden-
zoning-social-justice.html">written a lot</a> about exclusionary zoning built explicitly on the attempt to segregate based on race. Has that all morphed into economic discrimination?
</p>
<h4 id="ekmiXu">
Richard Kahlenberg
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="x0K7nO">
In certain communities, there is still an intent to segregate by race, so I don’t want to downplay that, but having said that, there’s certainly evidence that the issue of exclusionary zoning is not only about race.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="V4r16L">
We know in predominantly white communities that wealthy whites will use zoning to exclude lower-income whites. We also know, for example, in Prince George’s County, Maryland, a predominantly Black community, that there are efforts by wealthier Black people to exclude lower-income Black people through exclusionary zoning.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xE0jyk">
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="FZntD4">
In some white, liberal communities, you will hear people say they are delighted to have a Black doctor or lawyer move in next door. And so they feel virtuous for no longer excluding directly based on race, without acknowledging that they’d be highly uncomfortable with working-class Black people or white people moving into the neighborhood.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xoQCco">
So I think it’s important that we recognize that there’s exclusion going on by both race and class, which is why we need some new tools to beef up the existing laws.
</p>
<h4 id="N7Gd8z">
Jerusalem Demsas
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="nsaNb3">
I think one of the most interesting parts of when you look at Supreme Court history in this space is the entrenching of the idea that apartments and multi-family housing are inherently a nuisance. In <em>Euclid v. Ambler </em>(1926) the Court wrote:
</p>
<blockquote>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="m2WNI9">
“depriving children of the privilege of quiet and open spaces for play, enjoyed by those in more favored localities — until, finally, the residential character of the neighborhood and its desirability as a place of detached residences are utterly destroyed. Under these circumstances, apartment houses … come very near to being nuisances.”
</p>
</blockquote>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="o50XX2">
And in the American context, thinking of multi-family housing as inherently a nuisance is pretty normalized. Can you talk a little bit about how this idea has played an important role in perpetuating economic segregation?
</p>
<h4 id="Th7psJ">
Richard Kahlenberg
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="JV0y9h">
The <em>Euclid</em> decision that you mentioned is fascinating because while the Supreme Court ultimately upheld economically discriminatory zoning, citing this idea that apartments are a nuisance, the lower court recognized that this is clear class discrimination.
</p>
<div class="c-float-right">
<aside id="113V5u">
<q>“The notion that an apartment is a nuisance is a class-laden concept”</q>
</aside>
</div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="DM0NWe">
And that is what’s going on — the notion that an apartment is a nuisance is a class-laden concept connected to the idea that there is a negative effect on wealthier people when lower-income people are in proximity.
</p>
<h4 id="GwTDtZ">
Jerusalem Demsas
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="9GgAIs">
So what is your solution here? You’re proposing an Economic Fair Housing Act, what is that?
</p>
<h4 id="DUMSdy">
Richard Kahlenberg
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="5EE4k5">
So the idea of the Economic Fair Housing Act would extend the 1968 Fair Housing Act protection against racial discrimination to include protection against income discrimination by the government.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="U0pEpK">
When local governments adopt <a href="https://www.washingtonpost.com/news/wonk/wp/2017/09/25/snob-zoning-is-
racial-housing-segregation-by-another-name/">“snob zoning” laws</a>, they’re effectively saying we don’t want lower- income people in our community, and that’s a form of economic discrimination. The Economic Fair Housing Act would allow plaintiffs who are harmed by government-sponsored income discrimination to sue in federal court the way one currently can under the Fair Housing Act for racial discrimination.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="wpL358">
The new law would draw upon the concept of “disparate impact,” which is used in the Fair Housing Act. So a plaintiff wouldn’t have to show that the government’s <em>intent</em> is to discriminate based on income, but only that exclusionary zoning has the <em>effect</em> of discriminating based on income. As with racial disparate impact suits, the burden would shift to the local government to prove that its policy is necessary to achieve a valid interest.
</p>
<h4 id="3v7j91">
Jerusalem Demsas
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ExBLPO">
There are a lot of judges who might say that there is a valid interest in upholding exclusionary zoning, building on the established idea that apartments — and by extension working-class and middle-class people — are nuisances.
</p>
<h4 id="xfqZ50">
Richard Kahlenberg
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Q7uOUr">
I think many judges will see through the pretexts offered by local governments. If, say, governments indicate they want to minimize traffic and parking congestion, a reasonable court is likely to press them: Is it really “necessary” to ban all duplexes and triplexes?
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="KleLZn">
But to guard against conservative judges watering down the standard, it would be possible to include some process-oriented and results-oriented guardrails in the legislation. In<a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__tcf.org_content_report_tearing-2Dwalls-2Dbiden-2Dadministration-2Dcongress-2Dcan-2Dreduce-2Dexclusionary-2Dzoning_&amp;d=DwMFaQ&amp;c=7MSjEE-
cVgLCRHxk1P5PWg&amp;r=nLZhJpbveNo4l8b2bVcMMF_TZgU6MrKE3mDknTHXlCY&amp;m=2L037RYLXcwf0sRmwue5QMYZqyqRjlUTL4lyQfjQIPs3gg0o4npALRRRYxgLQNKL&amp;s=_ZQlR_N8PAZBLxroD2TAj6seJBXnNjANl9kH2pd3_S8&amp;e="> this report</a>, I suggested a ban on duplexes and triplexes could make a zoning policy presumptively illegitimate as a matter of process, and zoning policies in a community that had a very small share of affordable housing might be presumptively illegitimate as a matter of outcomes.
</p>
<h4 id="Fl3UUw">
Jerusalem Demsas
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="R1Asu2">
My understanding with the Fair Housing Act is that the difficulty of enforcement happens in a couple of places.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="C0TLSJ">
One is that the “disparate impact” standard is actually quite difficult to reach, and there are many judges that are hostile to that analysis. And secondly that it requires just a ton of resources to suss out the disparate impact.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="1zLrbj">
You often have to determine the counterfactual of what would have happened if a different legal system existed or what type of people would have lived in a development if it had not been blocked. It sometimes requires a mix of statisticians, economists, and sociologists in addition to lawyers to do that analysis.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Yv7v1O">
So, how does adding economic discrimination help solve that core issue?
</p>
<h4 id="bPv2py">
Richard Kahlenberg
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="dAj8s6">
I think it would make a big dent. The criticisms you cite of the Fair Housing Act are legitimate. Having said that, when the law was passed in 1968, I think it had two big impacts.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="U7xSSt">
One is the impact on culture. If you go back to <a href="https://www.washingtonpost.com/news/wonk/wp/2015/07/09/white-views-
on-desegregation-have-long-lagged-behind-the-law/">polling</a> in the 1960s, a majority of white people said that whites should have the right to keep Black people out of neighborhoods. Today, virtually no one would say that, and so having a law on the books can change culture and delegitimize discrimination. I think it did a good job of delegitimizing racial discrimination, and the aim is that the Economic Fair Housing Act would play a similar role.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Xwpiit">
In terms of the consequences, if we look at levels of racial segregation in this country, they remain far too high, but they have declined about 30 percent since 1970.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="9cf21M">
Black-white segregation is often measured with a <a href="https://www.brookings.edu/blog/the-avenue/2018/12/17/black-white-segregation-edges-downward-
since-2000-census-shows/">dissimilarity index</a>, and it stood at 79 in 1970, and it’s at 55 in 2020. Meanwhile, income segregation has been headed in the opposite direction. It’s basically doubled since 1970. And so, while the Fair Housing Act is imperfect, it has had a positive impact on issues of racial discrimination in housing. And I think an Economic Fair Housing Act could have similar effects.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="oOTQzV">
In terms of the statistical analysis required, one of the arguments for an Economic Fair Housing Act is that it would be easier to show that exclusionary zoning policies have a disparate economic impact.
</p>
<h4 id="srrmW4">
Jerusalem Demsas
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="YCEA0T">
Oh, interesting. Why is that?
</p>
<h4 id="5AUXFm">
Richard Kahlenberg
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="kHDlwk">
Well, right now it’s a bit of a bank shot. These laws are effectively aimed at excluding based on income and then you have to show how race and income interact. So it just removes one step in the process.
</p>
<h4 id="pLwS3y">
Jerusalem Demsas
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="pWD4um">
When the federal government has attempted to impose desegregation on communities, particularly with school desegregation, we see a ton of backlash, much of which is successful at maintaining segregation.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="425o7e">
Are you worried that legislation like this will just result in states and localities getting more wily at getting around this new law and not solve the underlying problems in the long run?
</p>
<h4 id="jhhitl">
Richard Kahlenberg
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="h81RoO">
So I would say a couple of things.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="7x87QY">
One, if you look at the history of school desegregation, there was enormous backlash to federal efforts to desegregate. But, at the end of the day, school desegregation in the South worked. That is to say, although there was political resistance, over time the South went from being the most segregated part of the country in terms of their schools, to the most integrated part of the country, and we saw the achievement gap between Black and white students fall considerably during the era of desegregation.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="CKNc9A">
So, although it took a long time — there was enormous inaction between Brown in 1954 and when federal government efforts to desegregate actually took off in the late 1960s — it was enormously effective for an important group of students who benefited from the policy.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="76aWXA">
More to the point, the Fair Housing Act was very controversial at the time. There were US senators who <a href="https://washingtonmonthly.com/2021/05/20/the-limits-of-the-fair-housing-act/">lost their jobs over supporting [fair housing</a>]. But today, the concept is broadly accepted, and you wouldn’t gain political traction from saying you want to repeal the federal Fair Housing Act.
</p>
<h4 id="qoAPc6">
Jerusalem Demsas
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="0Lv9Zj">
Contrasting this with other attempts by the federal government to address this problem — for instance, the grants the White House has proposed to provide planning and technical grants for localities that want to willingly re-zone — it seems like the winds are turning toward offering carrots (and very small carrots at that) rather than engaging in anything that could appear punitive.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="UbfjtW">
Do you think the political winds are shifting away from being able to enact policies like the Economic Fair Housing Act?
</p>
<h4 id="T0QGMr">
Richard Kahlenberg
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="HKxLuM">
Well, let me answer that in a couple of ways. I’m very supportive of efforts to either essentially bribe localities into doing the right thing through a Race to the Top program if you don’t reduce exclusionary zoning. I think that’s a good effort, but I think that the Economic Fair Housing Act offers something both substantively and politically that’s better.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="dFgPWK">
I think part of the problem with the existing federal proposals is that they suggest that exclusionary zoning is bad policy because it blocks opportunity and makes housing less affordable and damages the planet. All of those things are true, but what I think the Economic Fair Housing Act tries to do is say it’s not just bad policy, it’s immoral for governments to erect barriers that exclude and discriminate based on income … because it’s shameful what’s going on.
</p>
<div class="c-float-right">
<aside id="12ssXB">
<q>“People’s eyes glaze over when you talk about zoning. People understand that when white people were throwing rocks at buses carrying Black children to school … that’s wrong.”</q>
</aside>
</div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="6CnZks">
I also think the Economic Fair Housing Act framing will do a better job of raising awareness of the issue. I’m working on a book now called <em>The Walls We Don’t See</em> because people’s eyes glaze over when you talk about zoning.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="TFy45W">
People understand that when white people were throwing rocks at buses carrying Black children to school in order to desegregate, that’s wrong. It’s dramatic. The Economic Fair Housing Act does a better job than those other efforts to make people see what’s going on. It’s also more comprehensive than Build Back Better’s Unlocking Possibilities Program, which would reach a small number of places that are incentivized to make reforms. But this is comprehensive, it’s everywhere.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="WfcqTq">
So, I think this would be more effective than all those other approaches. But going back to the point I was making earlier, I think the economic framing is absolutely essential. I’ve been reading Heather McGhee’s book, <a href="https://www.penguinrandomhouse.com/books/564989/the-sum-of-us-by-heather-mcghee/"><em>The Sum of Us</em></a><em>, </em>which I think is just brilliant.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="PaRqvU">
One of her points is that if you want to make progress in society, you have to show white people how racism hurts them, and this is a classic example of where zoning began as racial in character and shifted to economic in order to exclude by race and ended up pulling in a lot of working-class whites as well.
</p>
<h4 id="g8Kmbg">
Jerusalem Demsas
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="sAVm21">
Can you speak more to the political coalition- building benefits of the economic framing approach?
</p>
<h4 id="m0KP1Y">
Richard Kahlenberg
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="GBM94m">
If you look at what drove Donald Trump, a lot of it was what Michael Sandel called the <a href="https://www.theguardian.com/books/2020/sep/06/michael-sandel-the-populist-backlash-has-been-a-revolt-against-the-
tyranny-of-merit">politics of humiliation</a>. And it <em>is</em> humiliating for working-class white people with less education to feel as though cultural elites are looking down on them — as they do.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="pREFrI">
I would never say it’s as bad as racism, but there is a way that economic framing helps unite these two groups that have been at war with each other for decades — working-class white people and people of color. In a common sense, they are being looked down upon for different reasons by well-to-do white people. So I think the politics are powerful here.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="IFMV6I">
We’ve seen that in Oregon and California where there are these fascinating political coalitions of conservative rural white legislators and urban liberal legislators of color who, not always, but in large measure have come together to defeat wealthier white suburban legislative interests in making the case for reform.
</p>
<h4 id="CPPfzo">
Jerusalem Demsas
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="sOjV8O">
The Economic Fair Housing Act which you have been fighting for for years is now getting legislative attention.
</p>
<h4 id="ELLzxj">
Richard Kahlenberg
</h4>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="YcXuKy">
I’m excited that there’s interest on Capitol Hill and that Rep. Emanuel Cleaver, who is chair of the subcommittee on housing in the House, is working on draft legislation to create an Economic Fair Housing Act.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="UyIu09">
He held hearings back in October on exclusionary zoning, and there’s a comment that he made at the beginning of the hearing which I found to be very profound. He said he was in Kansas City, he worked on zoning matters as a local official, and he said you just learn a lot about human nature and what people are really like when issues of zoning come up.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="k5hDRf">
I think someone like him, who understands the importance of zoning and the way it affects disadvantaged people, working- class people, middle-class people who are excluded from higher-opportunity neighborhoods — I’m excited that someone like him is interested in moving forward with this type of legislation.
</p>
<ul>
<li><strong>How seditious conspiracy charges change the January 6 narrative</strong> -
<figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><img alt="Stewart Rhodes, the recently indicted founder of the Oath Keepers, in a photo by the Washington
Post via Getty Images on February 28, 2021, in Fort Worth, Texas." src="https://cdn.vox-cdn.com/thumbor/EwAR-
LKFTybV0Sb8A0On8gI0dSg=/0x0:4032x3024/1310x983/cdn.vox-cdn.com/uploads/chorus_image/image/70397503/1231796848.0.jpg"/></p>
<figcaption>
Stewart Rhodes, the recently indicted founder of the Oath Keepers, on February 28, 2021, in Fort Worth, Texas. | Aaron C. Davis/The Washington Post via Getty Images
</figcaption>
</figure>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Stewart Rhodes is facing the most serious charges yet in connection with January 6.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="SEgO95">
On Thursday, federal prosecutors <a href="https://www.justice.gov/opa/pr/leader-oath-keepers-and-10-other-individuals-indicted-federal-court-seditious-
conspiracy-and">charged</a> Oath Keepers leader Stewart Rhodes and 10 others with seditious conspiracy for their role in the January 6 attacks on the US Capitol.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="LvpWH9">
That charge — the most serious yet to come out of the investigation — is one of several in <a href="https://www.justice.gov/opa/press-release/file/1462481/download">the indictment</a> unsealed Thursday, which alleges Rhodes and his co-defendants brought small arms to the Washington, DC, area; engaged in combat training to prepare for the attacks; and made plans to stage quick-reaction forces to support insurrectionists.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="H5Q6y5">
Rhodes was <a href="https://apnews.com/article/stewart-rhodes-arrested-oath-
keepers-jan-6-insurrection-70019e1007132e8df786aaf77215a110">taken into custody Thursday</a> in Texas and is among the highest-profile arrests made in the investigation into last year’s attacks on the Capitol, although <a href="https://www.washingtonpost.com/politics/2021/12/31/capitol-deadly-attack-insurrection-arrested-convicted/">more than 700 people</a> have thus far been arrested and charged in connection with January 6.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="78T6TD">
Rhodes’s group, the <a href="https://www.theatlantic.com/magazine/archive/2020/11/right-wing-militias-civil-war/616473/">Oath Keepers</a>, is “one of the largest far-right antigovernment groups in the US today,” <a href="https://www.splcenter.org/fighting-hate/extremist-files/group/oath-keepers">according to the Southern Poverty Law Center</a>. Founded in 2009, the group’s members have a history of attending protests while heavily armed, clashing with law enforcement, and <a href="https://www.vox.com/policy-and-politics/2016/11/7/13489640/oath-keepers-donald-trump-
voter-fraud-intimidation-rigged">supporting former President Donald Trump’s baseless election fraud claims</a>.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="WEZ8JQ">
Thursday’s indictments are also the first seditious conspiracy charges in the investigation so far, and the first the Justice Department has brought in more than a decade. <a href="https://apnews.com/article/riots-
conspiracy-9d22bdd4e2d4d786531ebe0fb8095de4">Seditious conspiracy</a> isn’t the same as treason, but it’s also not terribly far off; as former federal prosecutor Laurence Tribe <a href="https://www.nbcnews.com/think/opinion/stewart-
rhodes-oath-keepers-indictment-puts-january-6-plotters-notice-ncna1287540">wrote for NBC News on Saturday</a>, the “crime is, in effect, treason’s sibling.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="sEAHhY">
Specifically, <a href="https://www.law.cornell.edu/uscode/text/18/2384">seditious conspiracy</a> occurs when two or more people work together to plan to overthrow the government or prevent the execution of its laws.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="8yuC9m">
In the <a href="https://www.justice.gov/opa/press-release/file/1462481/download">case against Rhodes</a> and his alleged co- conspirators, the government presented evidence in the charging documents that shortly after the November 3, 2020, election Rhodes told his followers to, “Prepare your mind, body, and spirit” because, “We aren’t getting through this without a civil war.” In December, Rhodes promised a “bloody, massively bloody revolution” should a peaceful transfer of power occur, and in the lead-up to the attacks purchased thousands of dollars’ worth of weapons, ammunition, and related tactical gear.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="eSP8I9">
Other defendants in the case are alleged to have set up paramilitary training groups, and created private Signal groups to discuss their operations, including procuring weapons and establishing a <a href="https://twitter.com/oneunderscore__/status/1481726769606520832?s=20">quick reaction force</a> outside the DC area to bring in additional insurrectionists and weapons.
</p>
<div id="Z2ucM1">
<blockquote class="twitter-tweet">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" dir="ltr" lang="en">
Reading this Oath Keepers indictment.<br/><br/>These posts on TheDonald from January 5th make a lot more sense now.<br/><br/>The plan was to go all night and transport in the guns later, once they felt they had control over the Capitol. <a href="https://t.co/5Nq2tXHm8j">pic.twitter.com/5Nq2tXHm8j</a>
</p>
— Ben Collins</blockquote></div></li>
</ul>
<ol class="example" type="1">
<li><a href="https://twitter.com/oneunderscore__/status/1481726769606520832?ref_src=twsrc%5Etfw">January 13, 2022</a>
</li>
</ol>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="UraacX">
The new indictments are a significant step up from previous charges in the case, which range in seriousness from <a href="https://www.nytimes.com/2021/11/17/us/politics/qanon-shaman-
jan-6-sentenced.html">disorderly conduct to obstructing an official proceeding before Congress</a>, and have so far resulted in sentences up to 41 months in prison. In comparison, seditious conspiracy carries a potential sentence of <a href="https://www.nbcnews.com/think/opinion/stewart-rhodes-oath-keepers-indictment-puts-january-6-plotters-notice-
ncna1287540">20 years in prison</a>.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="RErYFG">
The indictment is “major news in [the] effort to hold extremists accountable for their role in #Jan6 insurrection,” the <a href="https://www.splcenter.org/fighting-hate/extremist-
files/ideology/antigovernment">Southern Poverty Law Center’s anti-government desk</a> told Vox via email. “January 6th was a culmination of years of poor behavior on Rhodes [sic] part. It felt like this was always where he and Oath Keepers were headed, but many of us had hoped that we could have prevented it.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="3VEDg0">
The new charges also refute the argument that narratives about the January 6 attack are overblown because no participants had yet been charged with sedition. As the Washington Post’s <a href="https://www.washingtonpost.com/politics/2022/01/13/fox-news-right-pitched-
no-sedition-charges-proof-jan-6-wasnt-an-insurrection-now-what/">Aaron Blake</a> pointed out on Thursday, Fox News’ Brit Hume had tweeted just hours before Rhodes’s arrest, “Let’s base our view on whether 1/6 was an ‘insurrection’ on whether those arrested are charged with insurrection. So far, none has been.”
</p>
<div id="ZDkCZz">
<blockquote class="twitter-tweet">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" dir="ltr" lang="en">
Here’s a thought. Let’s base our view on whether 1/6 was an “insurrection” on whether those arrested are charged with insurrection. So far, none has been. <a href="https://t.co/szsAGU3bz0">https://t.co/szsAGU3bz0</a>
</p>
— Brit Hume (<span class="citation" data-cites="brithume">@brithume</span>) <a href="https://twitter.com/brithume/status/1481649782841962500?ref_src=twsrc%5Etfw">January 13, 2022</a>
</blockquote>
</div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="mxobUb">
Hume’s tweet echoes months of Fox News hosts’ and guests’ attempts, along with <a href="https://thefederalist.com/2022/01/10/americas-justice-system-says-jan-6-was-neither-a-terrorist-attack-nor-an-
insurrection/">other conservatives</a>, to downplay the idea that the attacks on January 6 rise to the level of insurrection.
</p>
<h3 id="Rq4y1h">
Historically, seditious conspiracy prosecutions are rare and difficult
</h3>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="uPO8ia">
Seditious conspiracy charges are rare — so rare that, as the SPLC points out, this is just the fourth time in the past 80 years that the statute has been used against right-wing extremists in the US.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="z4Gq6x">
Previously, in 2010, members of a small Christian militia group in Michigan called <a href="https://www.npr.org/templates/story/story.php?storyId=125856761">the Hutaree</a> were indicted on seditious conspiracy charges, and before that, in the late 1980s, white supremacist militia members in Arkansas were charged with the same crime. In both cases, they were acquitted.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="5Oe6Ey">
That means the stakes for the Justice Department’s prosecution of Rhodes and his cohort are high, even as lawmakers in Congress continue to seek accountability for January 6 along different avenues. “It’s that significant of a moment,” the SPLC told Vox.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="ZroTJ6">
<a href="https://www.lawfareblog.com/last-time-justice-department-prosecuted-seditious-conspiracy-
case">According to a 1993 case</a>, <em>United States v. Lee</em>, proof of a conspiracy rests on establishing that everyone in the conspiracy shares “a ‘unity of purpose,’ the intent to achieve a common goal, and an agreement to work toward that goal”; previous seditious conspiracy cases have failed in part because the government failed to prove that unity, or to establish exactly what defendants were planning to do.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="gCh8CZ">
Even when cases are more clear- cut, there are barriers; as historian Kathleen Belew <a href="https://twitter.com/kathleen_belew/status/1481700975882776579?s=20">described on Twitter</a> Thursday, cultural and circumstantial factors may have contributed to the 1988 acquittal of the extremists in Arkansas, despite a surfeit of apparent evidence.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="EtItM3">
“Seditious conspiracy charges against Oath Keepers will seek to show that Jan 6 was not just a ‘protest’ … but an organized and pre-planned [attack] on American democracy,” <a href="https://twitter.com/kathleen_belew/status/1481702563531702276?s=20">Belew tweeted</a>. “The stakes are high, but there are a lot more tools today than existed in 1987-88: an FBI aware of and willing to confront white power and militant right violence; a DOD aware of the problem and taking action; hundreds of journalists telling better and more complete stories.”
</p>
<div id="olt2dJ">
<blockquote class="twitter-tweet">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" dir="ltr" lang="en">
The stakes are high, but there are a lot more tools today than existed in 1987-88: an FBI aware of and willing to confront white power and militant right violence; a DOD aware of the problem and taking action; hundreds of journalists telling better and more complete stories (20)
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">— Kathleen Belew (<span class="citation" data-cites="kathleen_belew">@kathleen_belew</span>) <a href="https://twitter.com/kathleen_belew/status/1481702834257248261?ref_src=twsrc%5Etfw">January 13, 2022</a></p>
</blockquote>
</div>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="3orhcJ">
In fact — and perhaps in foreshadowing of Thursday’s indictments — the DOJ <a href="https://apnews.com/article/united-states-national-security-
terrorism-899caf47624dd8741d04f73e65659e68">announced</a> last week it was establishing a unit dedicated to investigating and prosecuting domestic terrorism, shortly after the one-year anniversary of the January 6 attack.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="jwpvy6">
“We have seen a growing threat from those who are motivated by racial animus, as well as those who ascribe to extremist anti-government and anti-authority ideologies,” Assistant Attorney General Matthew Olsen told lawmakers.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="fKtn5f">
Thursday’s indictment, however, could help combat that threat. Jonathon Moseley, an attorney for Stewart Rhodes and his co-defendant Kelly Meggs, told Vox in a phone interview that “the Oath Keepers in general have been pretty much stalled in any of their operations during this whole year.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="lfUvE8">
“So a lot is going to depend on how the trial goes, what the outcome is. If they’re found guilty, they’re going to be sort of a pariah … so I think a lot is at stake in terms of the viability of the organization and its movement,” Moseley said.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="xPVVjs">
The indictment could also affect the ability of extremist groups to plan attacks like the one on January 6, Michael Edison Hayden, a SPLC spokesperson and senior investigative reporter, told Vox.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="NWH8sj">
“Extremists are also paying close attention to the use of Signal” — an <a href="https://www.vox.com/recode/22226618/what-is-signal-whatsapp-telegram-download-encrypted-messaging">encrypted messaging app</a> — “in making this arrest,” Hayden said. “So many far-right figures are perpetually chasing an online space to plan in secret and Signal’s presence in Rhodes’ indictment is a very clear warning sign that they don’t have any great options left. It’s an arrest that will likely inspire quite a bit of paranoia.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="kRmME0">
Rhodes himself maintained his innocence during an interview with the FBI last year and in a subsequent appearance in Texas early last year, <a href="https://www.theguardian.com/world/2022/jan/14/stewart-rhodes-oath-keepers-january-6-us-
capitol-attack">the Guardian reports</a>. “I may go to jail soon, not for anything I actually did, but for made-up crimes,” Rhodes said at the time.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="HhfWJG">
Rhodes has <a href="https://www.nytimes.com/2021/07/09/us/politics/stewart-rhodes-oath-keepers-fbi.html">denied in FBI interviews</a> that he ordered members of his group to breach the Capitol building, saying that anyone who did went in only to give medical aid after they heard someone had been shot, and he did not personally breach the Capitol.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="Z11mDI">
Even beyond the futures of Rhodes and the Oath Keepers, the implications for Thursday’s indictments could be far-reaching. More than a year after January 6, 2021, both the DOJ and Congress continue to probe the attack, but the DOJ has far more staying power: If Republicans win back the House in the midterm elections, DOJ’s seditious conspiracy case will continue, but the same can’t be said for the January 6 select committee, which could be hamstrung or dismantled if the balance of power changes in the House next year.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom" id="t8n869">
Despite the improved resources and focus on domestic extremism in 2022, the government’s case isn’t necessarily a slam-dunk. It’s still momentous, however: As <a href="https://twitter.com/kathleen_belew/status/1481702563531702276?s=20">Belew tweeted</a>, “the outcome of this prosecution will be enormously important if we hope to curb further violent attacks on people, institutions, and democracy itself.”
</p>
<h1 data-aos="fade-right" id="from-the-hindu-sports">From The Hindu: Sports</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Hyderabad bids to host Formula E World championship</strong> - The race will be held on the 2.37 km track in and around the Secretariat Complex encompassing the Lumbini Park Road.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Australian Open | Osaka finding joy again as she kicks off Melbourne Park defence</strong> - “It always feels special to come back here,” said the 13th seed, who will next face American Madison Brengle</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Root “sacrifices” opportunity to enter IPL mega auction</strong> - The wait to see the 31-year-old feature in lucrative league increased further as he has decided to prioritise the English Test team, which just succumbed to an embarrassing 0-4 Ashes defeat</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Australian Open | Nadal launches Grand Slam record bid by steamrolling Giron</strong> - With Djokovic sent packing by Australian authorities and Roger Federer absent, the Spaniard can snatch the men’s all- time Slam record outright by claiming the title at Melbourne Park.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>U-19 WC | England register seven-wicket win over Bangladesh</strong> - Bangladesh’s struggle from the onset can be gauged from the fact that only four of their batters managed double digit scores, with last man Mondal top-scoring with a 41-ball unbeaten knock which</p></li>
</ul>
<h1 data-aos="fade-right" id="from-the-hindu-national-news">From The Hindu: National News</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Applications invited for best teacher award</strong> - St. Berchmans College, Changanassery, has invited nominations/applications for the Berchmans Best Teacher Award. Teachers serving in colleges affiliat</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>27% seats for OBC in local body polls: Maharashtra moves SC urging recall of direction</strong> - Court had passed order on finding that State had not complied with ‘triple test’ requirement before reserving local body seats for OBC</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Bharatiya Mazdoor Sangh plans protests for universal pension scheme</strong> - RSS-affiliated trade union to picket EPFO offices</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Vaccination for students at 967 schools: Minister</strong> - No major change in functioning of schools for Classes 10 to 12.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Veteran Maharashtra leader N.D. Patil no more</strong> - Maharashtra’s senior most political leader, a towering figure in state’s social reform and left movement and a Marxist whose unwavering loyalty to the</p></li>
</ul>
<h1 data-aos="fade-right" id="from-bbc-europe">From BBC: Europe</h1>
<ul>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Djokovic back in Serbia after Australia deportation over visa row</strong> - The tennis star arrives in Belgrade after being deported from Australia over his Covid vaccination status.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Credit Suisse boss Horta-Osorio resigns over Covid breaches</strong> - Antonio Horta-Osorio leaves the bank after breaking UK quarantine rules to watch tennis at Wimbledon.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Anne Frank betrayal suspect identified after 77 years</strong> - A new investigation identifies a suspect who may have told the Nazis about the Jewish diarist’s hideout.</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Nino Cerruti: Italian fashion great dies aged 91</strong> - The celebrated designer and businessman once said: “I have always dressed the same person, myself.”</p></li>
<li data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Russia-Ukraine: US warns of ‘false-flag’ operation</strong> - Russia is plotting to stage acts of provocation to create a pretext to invade Ukraine, a US official says.</p></li>
</ul>
<h1 data-aos="fade-right" id="from-ars-technica">From Ars Technica</h1>
<ul>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>North Korean hackers stole nearly $400 million in crypto last year</strong> - “Banner year” thanks to skyrocketing cryptocurrency values, vulnerable startups. - <a href="https://arstechnica.com/?p=1825925">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Logitech Signature M650: A quiet wireless mouse for big, small, or left hands</strong> - A mid-priced, cable-free option strikes the right balance. - <a href="https://arstechnica.com/?p=1824831">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Pregnant people are still not getting vaccinated against COVID</strong> - Misinformation and muddled public health messaging have failed expectant parents. - <a href="https://arstechnica.com/?p=1826019">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>The weekend’s best deals: HBO Max, new AirPods, Apple Watch Series 7, and more</strong> - Dealmaster also includes Bluetooth speakers, gaming headsets, and the Mac Mini. - <a href="https://arstechnica.com/?p=1825888">link</a></p></li>
<li><p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"><strong>Backdoor RAT for Windows, macOS, and Linux went undetected until now</strong> - Never-before-seen, cross-platform SysJoker came from an “advanced threat actor.” - <a href="https://arstechnica.com/?p=1826079">link</a></p></li>
</ul>
<h1 data-aos="fade-right" id="from-jokes-subreddit">From Jokes Subreddit</h1>
<ul>
<li><strong>A guy walked into a bar with a monkey</strong> - <!-- SC_OFF -->
<div class="md">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
A guy walked into a bar with a monkey.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
The monkey grabbed some olives off the bar and ate them.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Then he grabbed some sliced limes and ate them. He then jumped onto the pool table and grabbed one of the balls.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
To everyone’s amazement, he stuck it in his mouth and somehow swallowed it whole.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
The bartender looked at the guy and said, “Did you see what your monkey just did?”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“No, what?”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“He just ate the cue ball off my pool table – whole!”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Yeah, that doesn’t surprise me,” replied the guy, “he eats everything in sight, don’t worry, I’ll pay for the cue ball.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
The guy finished his drink, paid his bill, paid for the stuff the monkey ate and left.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Two weeks later the guy came back and had his monkey with him.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
He ordered a drink and the monkey started running around the bar.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
The monkey found a cherry on the bar.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
He grabbed it, stuck it up his butt, pulled it out and then ate it.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Then the monkey found a peanut and again stuck it up his butt, pulled it out and ate it.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
The bartender asked, “Did you see what that filthy ape just did?”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“No, what?” asked the man.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Well, he stuck both a cherry and a peanut up his arse, then he pulled them out and ate them.”
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“Yeah, that doesn’t surprise me,” replied the guy.
</p>
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
“He’ll eat anything, but ever since he had to sh!t out that cue ball, he measures everything first.”
</p>
</div>
<!-- SC_ON -->
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/WorldlyReplacement63"> /u/WorldlyReplacement63 </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/s5sxlk/a_guy_walked_into_a_bar_with_a_monkey/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/s5sxlk/a_guy_walked_into_a_bar_with_a_monkey/">[comments]</a></span></p></li>
<li><strong>Why don’t you ever see elephants hiding in trees?</strong> - <!-- SC_OFF -->
<div class="md">
<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom">
Because they’re really good at it.
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Why do elephants paint their balls red?
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So they can hide in cherry trees.
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What is the loudest sound in the jungle?
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Giraffes eating cherries.
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/hot_duk"> /u/hot_duk </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/s5x780/why_dont_you_ever_see_elephants_hiding_in_trees/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/s5x780/why_dont_you_ever_see_elephants_hiding_in_trees/">[comments]</a></span></p></li>
<li><strong>A policeman is driving past a roadside apple stand when he notices the sign: “Apple seeds, guaranteed to make you smarter, $20 per seed.”</strong> - <!-- SC_OFF -->
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He pulls over and informs the vendor that it is fraud and false advertising to make absurd claims like this.
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“No, no, no,” the vendor tells the cop, “my apples are a special variety. A scientific miracle. Buy just one seed, eat it, and you will notice an increase in intelligence. If not, I promise to refund your 20 dollars.”
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“Alright,” says the cop. “But, if this doesn’t work, I’m shutting your operation down.” He hands over a 20 dollar bill, takes the seed, chews it up, and waits for it to kick in.
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After a few moments, he says, “You know, even if you’re not lying, I could have bought a whole bag of your apples and had enough seeds to last me months.”
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“Ah, yes!” says the vendor. “It’s working already!”
</p>
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/PlayFree_Bird"> /u/PlayFree_Bird </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/s5va8e/a_policeman_is_driving_past_a_roadside_apple/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/s5va8e/a_policeman_is_driving_past_a_roadside_apple/">[comments]</a></span></p></li>
<li><strong>A police officer is sitting in his cruiser watching for speeding cars.</strong> - <!-- SC_OFF -->
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He sees a car puttering along at 10 km/hr and thinks “this car is almost as dangerous as a speeder” and pulls them over.
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As he walks up to the car and little of lady driving rolls down the window and asks “is there something wrong officer?”
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“Well, yes” says the cop “why are you driving so slowly?”"
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“I’m going the limit” says the little old lady, very confused “the sign back there says 10.”
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“You’re mistaken ma’am, that sign was to tell you that this is route 10, the limit here 60.”
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“Oh, my” says the woman very embarrassed, “I am so sorry, I will pay closer attention to the signs.”
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At this point the police officer notices the other passengers in the car: three more elderly women, all very pale and wide-eyed, clutching the armrests with white-knucked hands.
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“Ma’am” he asks “are your passengers alright? They look quite shaken.”
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“Oh, they’ll be fine, dear” says the elderly woman “we just turned off of route 250.”
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/Nervous_Chipmunk7002"> /u/Nervous_Chipmunk7002 </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/s5s7yw/a_police_officer_is_sitting_in_his_cruiser/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/s5s7yw/a_police_officer_is_sitting_in_his_cruiser/">[comments]</a></span></p></li>
<li><strong>Guy has a tapeworm in his intestine and tries many doctors but everybody fails to remove.Finally he tries an alternative doctor whom everybody recommended heavily and visits him.</strong> - <!-- SC_OFF -->
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The doctor says: Come back tomorrow with two bananas and a Snickers bar. The patient is confused but does as he’s told.
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The next day he shows up with two bananas and a Snickers bar. The doctor proceeds to insert both bananas and the Snickers bar up the man’s ass.
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The doctor then says to him: Come back tomorrow with two bananas and a Snickers bar. The man is very confused but does as he’s told.
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The patient and the doctor repeat this process for 5 days. On the sixth day, the doctor tells the patient: Tomorrow bring two bananas but instead of a Snickers bar, bring a mallet. The patient is again confused but does as he’s told.
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The next day the doctor inserts both bananas up the guy’s butt and quickly grabs the mallet and waits.
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All of the sudden, the tapeworm pops out saying : Hey! Where’s my Snickers bar?
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WHAM!!!!
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<p data-aos="fade-left" data-aos-anchor-placement="bottom-bottom"> submitted by <a href="https://www.reddit.com/user/xerxes_dandy"> /u/xerxes_dandy </a> <br/> <span><a href="https://www.reddit.com/r/Jokes/comments/s5gzb0/guy_has_a_tapeworm_in_his_intestine_and_tries/">[link]</a></span> <span><a href="https://www.reddit.com/r/Jokes/comments/s5gzb0/guy_has_a_tapeworm_in_his_intestine_and_tries/">[comments]</a></span></p></li>
</ul>
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