diff --git a/archive-covid-19/14 June, 2021.html b/archive-covid-19/14 June, 2021.html new file mode 100644 index 0000000..acbc265 --- /dev/null +++ b/archive-covid-19/14 June, 2021.html @@ -0,0 +1,233 @@ + +
+ + + ++Background The safety and immunogenicity profile of COVID-19 vaccines when administered concomitantly with seasonal influenza vaccines has not yet been reported. Methods A sub-study on influenza vaccine co-administration was conducted as part of the phase 3 randomized trial of the safety and efficacy of NVX-CoV2373. The first ~400 participants meeting main study entry criteria and with no contraindications to influenza vaccination were invited to join the sub-study. After randomization in a 1:1 ratio to receive NVX-CoV2373 (n=217) or placebo (n=214), sub-study participants received an age-appropriate, licensed, open-label influenza vaccine with dose 1 of NVX-CoV2373. Reactogenicity was evaluated via electronic diary for 7 days post-vaccination in addition to monitoring for unsolicited adverse events (AEs), medically-attended AEs (MAAEs), and serious AEs (SAEs). Influenza haemagglutination inhibition and SARS-CoV-2 anti-spike IgG assays were performed. Vaccine efficacy against PCR-confirmed, symptomatic COVID-19 was assessed. Comparisons were made between sub-study and main study participants. Findings Sub-study participants were younger, more racially diverse, and had fewer comorbid conditions than main study participants. Reactogenicity events more common in the co-administration group included tenderness (70.1% vs 57.6%) or pain (39.7% vs 29.3%) at injection site, fatigue (27.7% vs 19.4%), and muscle pain (28.3% vs 21.4%). Rates of unsolicited AEs, MAAEs, and SAEs were low and balanced between the two groups. Co-administration resulted in no change to influenza vaccine immune response, while a reduction in antibody responses to the NVX-CoV2373 vaccine was noted. Vaccine efficacy in the sub-study was 87.5% (95% CI: -0.2, 98.4) while efficacy in the main study was 89.8% (95% CI: 79.7, 95.5). Interpretation This is the first study to demonstrate the safety, immunogenicity, and efficacy profile of a COVID-19 vaccine when co-administered with seasonal influenza vaccines. The results suggest concomitant vaccination may be a viable immunisation strategy. Funding This study was funded by Novavax, Inc. +
++In March 2021, Japan is facing a 4th wave of SARS-CoV-2 infection. To prevent further spread of infection, sera cross-neutralizing activity of patients previously infected with conventional SARS-CoV-2 against novel variants is important but is not firmly established. We investigated the neutralizing potency of 81 COVID-19 patients9 sera from 4 waves of pandemic against SARS-CoV-2 variants using their authentic viruses. Most sera had neutralizing activity against all variants, showing similar activity against B.1.1.7 and D614G, but lower activity especially against B.1.351. In the 4th wave, sera-neutralizing activity against B.1.1.7 was significantly higher than that against any other variants, including D614G. The cross-neutralizing activity of convalescent sera was effective against all variants but was potentially weaker for B.1.351. +
++Objectives: To assess the association between self-reported disability and deaths involving COVID-19 among adults in England. Design: Cohort study of >29 million adults using data from the Office for National Statistics Public Health Data Asset. Setting: People living in private households or communal establishments (including care homes) in England. Participants: 29,293,845 adults (47% male) aged 30-100 years (mean age = 56) present at the 2011 Census who were alive on 24 January 2020. The main exposure was self-reported disability from the 2011 Census. Main outcome measures: Death involving COVID-19, occurring between 24 January 2020 and 28 February 2021. We estimated the age-standardised mortality rate per 100,000 person-years at-risk, stratified by sex, disability status, and wave of the pandemic. We calculated hazard ratios (HRs) for disabled people compared with non-disabled people, adjusted for geographical factors, socio-demographic characteristics, and pre-pandemic health conditions. Results: Disabled people made up 17% of the study population, including 7% who were 9more-disabled9 and 10% 9less-disabled9. From 24 January 2020 to 28 February 2021, 105,213 people died from causes involving COVID-19 in England, 58% of whom were disabled. Age-adjusted analyses showed that, compared to non-disabled people, mortality involving COVID-19 was higher among both more-disabled people (HR=3.05, 95% CI: 2.98 to 3.11 in males; 3.48, 3.41 to 3.56 in females) and less-disabled people (HR=1.88, 95% CI: 1.84 to 1.92 in males; 2.03, 1.98 to 2.08 in females). Among people aged 30-69, HRs reached 8.47 (8.01 to 8.95) among more-disabled females and 5.42 (5.18 to 5.68) for more-disabled males. Sequential adjustment for residence type, geography, socio-demographics, and health conditions partly explained the associations, indicating that a combination of these factors contributed towards the increased risk. Conclusion: Disabled people in England had markedly increased risk of mortality involving COVID-19 compared to non-disabled people and should be prioritised within the pandemic response. +
++Background: To develop and validate an early-warning model to predict in-hospital mortality on admission of COVID-19 patients at an emergency department (ED).<br /> Methods: In total, 2782 patients were enrolled between March 2020 and December 2020, including 2106 patients (first wave) and 676 patients (second wave) in the COVID-19 outbreak in Italy. The first wave patients were divided into two groups with 1474 patients used to train the model, and 632 to validate it. The 676 patients in the second wave were used to test the model. Age, 17 blood analytes and Brescia chest X-ray score were the variables processed using a Random Forests classification algorithm to build and validate the model. ROC analysis was used to assess the model performances. A web-based death-risk calculator was implemented and integrated within the Laboratory Information System of the hospital. Results: The final score was constructed by age (the most powerful predictor), blood analytes (the strongest predictors were lactate dehydrogenase, D-dimer, Neutrophil/Lymphocyte ratio, C-reactive protein, Lymphocyte %, Ferritin std and Monocyte %), and Brescia chest X-ray score. The areas under the receiver operating characteristic curve obtained for the three groups (training, validating and testing) were 0.98, 0.83 and 0.78, respectively.<br />Conclusions: The model predicts in-hospital mortality on the basis of data that can be obtained in a short time, directly at the ED on admission. It functions as a web-based calculator, providing a risk score which is easy to interpret. It can be used in the triage process to support the decision on patient allocation. +
++The COVID-19 pandemic has lead to a worldwide effort to characterize its evolution through the mapping of mutations in the genome of the coronavirus SARS-CoV-2. As the virus spreads and evolves it acquires new mutations that could have important public health consequences, including higher transmissibility, morbidity, mortality, and immune evasion, among others. Ideally, we would like to quickly identify new mutations that could confer adaptive advantages to the evolving virus by leveraging the large number of SARS-CoV-2 genomes. One way of identifying adaptive mutations is by looking at convergent mutations, mutations in the same genomic position that occur independently. The large number of currently available genomes, more than a million at this moment, however precludes the efficient use of phylogeny-based techniques. Here, we establish a fast and scalable Topological Data Analysis approach for the early warning and surveillance of emerging adaptive mutations of the coronavirus SARS-CoV-2 in the ongoing COVID-19 pandemic. Our method relies on a novel topological tool for the analysis of viral genome datasets based on persistent homology. It systematically identifies convergent events in viral evolution merely by their topological footprint and thus overcomes limitations of current phylogenetic inference techniques. This allows for an unbiased and rapid analysis of large viral datasets. We introduce a new topological measure for convergent evolution and apply it to the complete GISAID dataset as of February 2021, comprising 303,651 high-quality SARS-CoV-2 isolates taken from patients all over the world since the beginning of the pandemic. A complete list of mutations showing topological signals of convergence is compiled. We find that topologically salient mutations on the receptor-binding domain appear in several variants of concern and are linked with an increase in infectivity and immune escape. Moreover, for many adaptive mutations the topological signal precedes an increase in prevalence. We demonstrate the capability of our method to effectively identify emerging adaptive mutations at an early stage. By localizing topological signals in the dataset, we are able to extract geo-temporal information about the early occurrence of emerging adaptive mutations. The identification of these mutations can help to develop an alert system to monitor mutations of concern and guide experimentalists to focus the study of specific circulating variants. +
++Introduction: The objective of this study is to analyse the specific immune response against SARS-CoV-2 in those affected by Long Covid (LC), attributable to T cells (cell-mediated immunity) and to carry out a parallel analysis of the humoral response and lymphocyte typing. Methodology: Descriptive cross-sectional study of 74 patients with LC for at least 4 months since diagnosis. The collected data were: information on the COVID-19 episode and the persistent symptoms, medical history and a specific cell-mediated immunity to SARS-CoV-2 through flow cytometry, assessing the release of interferon-gamma (IFN-Ɣ) by T4 lymphocytes, T8 lymphocytes and NK cells. Descriptive and comparative analyses were carried out. Results: Patients with LC had negative serology for Covid-19 in 89% of cases but 96% showed specific cellular immunity to SARS-CoV-2 an average of 9.5 months after infection: 89% of this response corresponded to T8 lymphocytes, 58% to NK cells, and 51% to T4 lymphocyte (20% negligibly positive). Most of them had altered immune cell typing and we found that T4 lymphocyte counts were low in 34% of cases and NK cell high in 64%. Macrophage populations were detected in the peripheral blood of 7% of them. Patients displayed a higher percentage of illnesses related to ″abnormal″ immune responses, either preceding SARS-CoV-2 infection (43%) or following it in 23% of cases. Conclusion: The immune system appears to have an important involvement in the development of LC and viral persistence could be the cause or consequence of it. Further analysis with a control group should be performed. +
++Objective: Key to slowing the spread of SARS-Cov-2 is adherence to preventive behaviours promoted through government policies, which may be influenced by policy awareness, attitudes and concerns about the virus and its impacts. This study assessed determinants of adherence to major coronavirus preventive behaviours, including demographics, attitudes and concerns, among Canadians during the first pandemic wave. Methods: As part of the iCARE study (www.iCAREstudy.com), we weighted data from two population-based, online surveys (April and June, 2020) of Canadian adults. Questions tapped into behaviour change constructs. Multivariate regression models identified determinants of adherence. Results: Data from 6,008 respondents (51% female) were weighted for age, sex, and province. Awareness of government policies was high at both time points (80-99%), and adherence to prevention behaviours was high in April (87.5%-93.5%) but decreased over time, particularly for avoiding social gatherings (68.1%). Adherence was worse among men, those aged 25 and under, and those currently working. Aligned with the Health Beliefs Model, perceptions of the importance of prevention behaviours and the nature of peoples COVID-19-related concerns were highly predictive of adherence. Interestingly, health and social/economic concerns predicted better adherence, but having greater personal financial concerns predicted worse adherence at both time points. Conclusion: Adherence to COVID-19 prevention behaviours was worse among men, younger adults, and workers, and deteriorated over time. Perceived importance of prevention behaviours measures and health and social/economic concerns predicted better adherence, but personal financial concerns predicted worse adherence. Results have implications for tailoring policy and communication strategies during subsequent pandemic waves. +
++Antigen tests for severe acute respiratory coronavirus 2 sometimes show positive lines earlier than their specified read time, although the implication of getting the results at earlier time is not well understood. This study aimed to evaluate the clinical utility of an antigen test by evaluating the time period to get positive results and by comparing the test sensitivity with that of a digital immunoassay (DIA) test. We prospectively collected additional nasopharyngeal samples from patients who had already tested positive for SARS-CoV-2 by reverse transcription PCR. The additional swab was used for an antigen test, QuickNavi™-COVID19 Ag, and the time periods to get positive results were measured. The sensitivity of QuickNavi™-COVID19 Ag was also compared with that of a DIA. In 84 of 96 (87.5%) analyzed cases, the results of QuickNavi™-COVID19 Ag were positive. The time to obtain positive results was 15.0 seconds in median (inter quartile range: 12.0-33.3, range 11-736), and was extended in samples with higher cycle thresholds (Ct) (p<0.001). Positive lines appeared within a minute in 85.7% of cases and within 5 minutes in 96.4%. The sensitivities of QuickNavi™-COVID19 Ag and the DIA were 87.5% (95% confident interval [CI]: 79.2%-93.4%) and 88.6% (95%CI: 75.4%-96.2%), respectively. Their results were concordant in 90.9% of cases, with discrepancies present only in cases with Ct values >32. QuickNavi™-COVID19 Ag immediately showed positive results in most cases, and the time to a positive reaction may have indicated the viral load. In addition, the sensitivity of the test was comparable to the DIA. +
+Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells to Treat Post COVID-19 “Long Haul” Pulmonary Compromise - Condition: Covid19
Intervention: Biological: COVI-MSC
Sponsor: Sorrento Therapeutics, Inc.
Not yet recruiting
Intramuscular VIR-7831 (Sotrovimab) for Mild/Moderate COVID-19 - Condition: Covid19
Intervention: Biological: VIR-7831
Sponsors: Vir Biotechnology, Inc.; GlaxoSmithKline
Not yet recruiting
Collecting Respiratory Sound Samples From Corona Patients to Extend the Diagnostic Capability of VOQX Electronic Stethoscope to Diagnose COVID-19 Patients - Condition: COVID-19
Intervention: Diagnostic Test: Electronic stethoscope
Sponsor: Sanolla
Recruiting
The Burden of COVID-19 Survivorship - Condition: Covid19
Intervention: Other: Exercise Training
Sponsor: Mayo Clinic
Not yet recruiting
Community-based Post-exposure Prophylaxis for COVID-19 - Condition: Covid19
Interventions: Other: Guduchi Ghanvati; Other: Standard guidelines
Sponsors: NMP Medical Research Institute; Aarogyam UK; Dr. Sarvepalli Radhakrishnan Rajasthan Ayurved University; Samta Ayurveda Prakoshtha, India; Padmanabhama Ayurveda Hospital and Research Centre
Completed
Detection of SARS-CoV-2 RNA in Coughed Droplets From Patients With COVID-19 - Condition: Covid19
Intervention: Device: PneumoniaCheck
Sponsors: Emory University; Georgia Tech Foundation
Recruiting
Favipiravir +/- Nitazoxanide: Early Antivirals Combination Therapy in COVID-19 - Condition: Covid19
Interventions: Drug: Favipiravir; Drug: Nitazoxanide; Other: Nitazoxanide Placebo
Sponsors: Coordinación de Investigación en Salud, Mexico; University College, London; Centro de Investigacion y Estudios Avanzados del Instituto Politecnico Nacional (CINVESTAV); Universidad Autonoma de Guadalajara; Siegfried Rhein S.A. de C.V.; Strides Pharma Science Limited; Hakken Enterprise
Not yet recruiting
Epidemiologic Intelligence Network (EpI-Net) to Promote COVID-19 Testing - Condition: Covid19
Intervention: Other: Epi-Net Intervention
Sponsors: Ponce Medical School Foundation, Inc.; Duke University; Harvard School of Public Health
Recruiting
Ivermectin Treatment Efficacy in Covid-19 High Risk Patients - Condition: COVID-19
Intervention: Drug: Ivermectin 0.4mg/kg/day for 5 days
Sponsor: Clinical Research Centre, Malaysia
Not yet recruiting
To Evaluate the Safety and Efficacy of TQ Formula in Covid-19 Participants - Condition: Covid19
Intervention: Drug: Black Seed Oil Cap/Tab
Sponsor: Novatek Pharmaceuticals
Recruiting
A Randomized, Controlled, Multicenter, Open Label Phase II Clinical Study to Evaluate Infliximab in the Treatment of Patients With Severe COVID-19 Disease - Condition: COVID-19
Interventions: Drug: Infliximab; Other: Standard of Care
Sponsors: Jena University Hospital; German Federal Ministry of Education and Research; Celltrion
Not yet recruiting
A Phase 2b Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study, Evaluating Efficacy and Safety of Allocetra-OTS in Patients With Severe or Critical COVID-19 With Associated Acute Respiratory Distress Syndrome (ARDS) - Condition: Covid19
Interventions: Drug: ALLOCETRA-OTS; Other: Placebo
Sponsor: Enlivex Therapeutics Ltd.
Not yet recruiting
Bifido- and Lactobacilli in Symptomatic Adult COVID-19 Outpatients - Condition: COVID-19 Respiratory Infection
Intervention: Other: Dietary Supplement
Sponsor: Nordic Biotic Sp. z o.o.
Not yet recruiting
Nicotinamide-based Supportive Therapy in Lymphopenia for Patients With COVID-19 - Conditions: Covid19; Lymphopenia
Intervention: Drug: nicotinamide
Sponsor: Qiang Hu
Completed
Safety and Efficacy of Dupilumab for Treatment of Hospitalized COVID-19 Patients - Condition: Covid19
Interventions: Biological: Dupilumab; Drug: Placebo
Sponsors: University of Virginia; PBM C19 Research, LLC (PBM); Virginia Catalyst, Virginia Biosciences Health Research Corporation (VBHRC)
Recruiting
Examining the interactions scorpion venom peptides (HP1090, Meucin-13, and Meucin-18) with the receptor binding domain of the coronavirus spike protein to design a mutated therapeutic peptide - The spike protein of SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus 2) interacts with the ACE2 receptor in human cells and starts the infection of COVID-19 disease. Given the importance of spike protein’s interaction with ACE2 receptor, we selected some antiviral peptides of venom scorpion such as HP1090, meucin-13, and meucin-18 and performed docking and molecular docking analysis of them with the RBD domain of spike protein. The results showed that meucin-18 (FFGHLFKLATKIIPSLFQ) had…
Perilla (Perilla frutescens) leaf extract inhibits SARS-CoV-2 via direct virus inactivation - CONCLUSION: Our results demonstrate for the first time that PLE is capable of inhibiting SARS-CoV-2 replication by inactivating the virion. Our data may prompt additional investigation on the clinical usefulness of PLE for preventing or treating COVID-19.
Positive Selection as a Key Player for SARS-CoV-2 Pathogenicity: Insights into ORF1ab, S and E genes - The human β-coronavirus SARS-CoV-2 epidemic started in late December 2019 in Wuhan, China. It causes Covid-19 disease which has become pandemic. Each of the five-known human β-coronaviruses has four major structural proteins (E, M, N and S) and 16 non-structural proteins encoded by ORF1a and ORF1b together (ORF1ab) that are involved in virus pathogenicity and infectivity. Here, we performed detailed positive selection analyses for those six genes among the four previously known human…
Molecular mechanism of anti-SARS-CoV2 activity of Ashwagandha-derived withanolides - COVID-19 caused by SARS-CoV-2 corona virus has become a global pandemic. In the absence of drugs and vaccine, and premises of time, efforts and cost required for their development, natural resources such as herbs are anticipated to provide some help and may also offer a promising resource for drug development. Here, we have investigated the therapeutic prospective of Ashwagandha for the COVID-19 pandemic. Nine withanolides were tested in silico for their potential to target and inhibit (i) cell…
Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to replicate and spread, although which RBPs control its life cycle remains largely unknown. Here, we employ a multi-omic approach to identify systematically and comprehensively the cellular and viral RBPs that are involved in SARS-CoV-2 infection. We reveal that SARS-CoV-2 infection profoundly remodels the cellular RNA-bound proteome,…
COVID-19 mRNA vaccination generates greater IgG levels in women compared to men - QUESTION: Is antibody response to COVID-19 mRNA vaccination similar in women and men?
Interaction of selected terpenoids with two SARS-CoV-2 key therapeutic targets: An in silico study through molecular docking and dynamics simulations - The outbreak of COVID-19 disease caused by SARS-CoV-2, along with the lack of targeted medicaments, forced the scientific world to search for new antiviral formulations. In the current emergent situation, drug repurposing of well-known traditional and/or approved drugs could be the most effective strategy. Herein, through computational approaches, we aimed to screen 14 natural compounds from limonoids and terpenoids class for their ability to inhibit the key therapeutic target proteins of…
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation - Acute respiratory distress syndrome (ARDS), an inflammatory condition with high mortality rates, is common in severe COVID-19, whose risk is reduced by metformin rather than other anti-diabetic medications. Detecting of inflammasome assembly in post-mortem COVID-19 lungs, we asked whether and how metformin inhibits inflammasome activation while exerting its anti-inflammatory effect. We show that metformin inhibited NLRP3 inflammasome activation and interleukin (IL)-1β production in cultured and…
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target - Cytokine storm and multi-organ failure are the main causes of SARS-CoV-2-related death. However, the origin of excessive damages caused by SARS-CoV-2 remains largely unknown. Here we show that the SARS-CoV-2 envelope (2-E) protein alone is able to cause acute respiratory distress syndrome (ARDS)-like damages in vitro and in vivo. 2-E proteins were found to form a type of pH-sensitive cation channels in bilayer lipid membranes. As observed in SARS-CoV-2-infected cells, heterologous expression of…
I(nsp1)ecting SARS-CoV-2-ribosome interactions - While SARS-CoV-2 is causing modern human history’s most serious health crisis and upending our way of life, clinical and basic research on the virus is advancing rapidly, leading to fascinating discoveries. Two studies have revealed how the viral virulence factor, nonstructural protein 1 (Nsp1), binds human ribosomes to inhibit host cell translation. Here, we examine the main conclusions on the molecular activity of Nsp1 and its role in suppressing innate immune responses. We discuss different…
Correction To: Ceftazidime is a potential drug to inhibit SARS-CoV-2 infection in vitro by blocking spike protein-ACE2 interaction - No abstract
Macrophage biomimetic nanocarriers for anti-inflammation and targeted antiviral treatment in COVID-19 - CONCLUSION: Collectively, such macrophage biomimetic nanocarriers based drug delivery system showed favorable anti-inflammation and targeted antiviral effects, which may possess a comprehensive therapeutic value in COVID-19 treatment.
Vitamin D attenuates COVID-19 complications via modulation of proinflammatory cytokines, antiviral proteins, and autophagy - Introduction: Global emergence of coronavirus disease-19 (COVID-19) has clearly shown variable severity, mortality, and frequency between and within populations worldwide. These striking differences have made many biological variables attractive for future investigations. One of these variables, vitamin D, has been implicated in COVID-19 with rapidly growing scientific evidence. Areas covered: The review intended to systematically explore the sources, and immunomodulatory the role of vitamin D…
A potential antiviral activity of Esculentoside A against binding interactions of SARS-COV-2 spike protein and angiotensin converting enzyme 2 (ACE2) - The recent emergence of the novel coronavirus (SARS-CoV-2) has resulted in a devastating pandemic with global concern. However, to date, there are no regimens to prevent and treat SARS-CoV-2 virus. There is an urgent need to identify novel leads with anti-viral properties that impede viral pathogenesis in the host system. Esculentoside A (EsA), a saponin isolated from the root of Phytolacca esculenta, is known to exhibit diverse pharmacological properties, especially anti-inflammatory activity….
Efficacy and safety of Dihydroorotate dehydrogenase (DHODH) inhibitors “Leflunomide” and “Teriflunomide” in Covid-19: A narrative review - Dihydroorotate dehydrogenase (DHODH) is rate-limiting enzyme in biosynthesis of pyrimidone which catalyzes the oxidation of dihydro-orotate to orotate. Orotate is utilized in the biosynthesis of uridine-monophosphate. DHODH inhibitors have shown promise as antiviral agent against Cytomegalovirus, Ebola, Influenza, Epstein Barr and Picornavirus. Anti-SARS-CoV-2 action of DHODH inhibitors are also coming up. In this review, we have reviewed the safety and efficacy of approved DHODH inhibitors…
폐마스크 밀봉 회수기 - 본 발명은 마스크 착용 후 버려지는 일회용 폐마스크를 비닐봉지에 넣은 후 밀봉하여 배출함으로써, 2차 감염을 예방하고 일반 생활폐기물과 선별 분리 배출하여 환경오염을 방지하는 데 그 목적이 있다. - link
COST EFFECTIVE PORTABLE OXYGEN CONCENTRATOR FOR COVID-19 - - link
METHOD OF IDENTIFYING SEVERE ACUTE RESPIRATORY SYNDROME CORONA VIRUS 2 (SARS-COV-2) RIBONUCLEIC ACID (RNA) - - link
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Erweiterbare Desinfektionsvorrichtung, umfassend: einen Hauptkörper, der eine umgekehrt U-förmige Basisplatte aufweist, wobei die umgekehrt U-förmige Basisplatte mit einer Öffnung versehen ist und jeweils eine Seitenplatte sich von zwei Seiten der umgekehrt U-förmigen Basisplatte nach außen erstreckt; und mindestens eine Desinfektionslampe, die in den auf zwei Seiten des Hauptkörpers befindlichen Seitenplatten angeordnet ist und eine Lichtemissionseinheit, eine Erfassungseinheit, eine Steuereinheit und eine Stromversorgungseinheit umfasst.
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Einfache Sterilisationsvorrichtung, mit einem Hauptkörper (11), der in Längsrichtung einen ersten Plattenabschnitt (111) und in Querrichtung einen zweiten Plattenabschnitt (112) aufweist, wobei der erste Plattenabschnitt (111) und der zweite Plattenabschnitt (112) L-förmig miteinander verbunden sind; und einer Sterilisationslampe (12), die an dem Hauptkörper (11) angeordnet ist und eine Lichtemissionseinheit (121), eine Sensoreinheit (122), eine Steuereinheit (123) und eine Stromeinheit (124) aufweist.
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Klemmarme aufweisende Desinfektionsvorrichtung, umfassend: einen Hauptkörper; eine Desinfektionslampe, die im Hauptkörper angeordnet ist und eine Lichtemissionseinheit, eine Erfassungseinheit, eine Steuereinheit und eine Stromversorgungseinheit umfasst; einen Klemmabschnitt, der auf einer Seite des Hauptkörpers angeordnet ist, wobei der Klemmabschnitt zwei gegenüberliegende Greifbacken umfasst, wobei mindestens eine der beiden Greifbacken mit einer Schwenkachse versehen ist, wobei ein Klemmraum durch passgenaues Schließen der beiden Greifbacken entsteht und die beiden Greifbacken jeweils mit einem Durchgangsloch versehen sind; einen Befestigungsabschnitt, der durch die Durchgangslöcher der beiden Greifbacken hindurchgeführt ist;und ein Schild, das auf einer Seite des Klemmabschnitts angeordnet und mit einem Aufnahmeloch versehen ist.
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Aufhängbare Sterilisationsvorrichtung, mit einem Hauptkörper (11); einer Sterilisationslampe (12), die an dem Hauptkörper (11) angeordnet ist und eine Lichtemissionseinheit (121), eine Sensoreinheit (122), eine Steuereinheit (123) und eine Stromeinheit (124) aufweist; einem Klemmabschnitt (13), der an einer Seite des Hautpkörpers (11) angeordnet ist und zwei gegenüberliegend angeordnete Klemmbacken (131) aufweist, wobei mindestens eine der beiden Klemmbacken (131) mit einem Achsbolzen (132) versehen ist, wobei die beiden Klemmbacken (131) beim Schließen einen Klemmraum (134) bilden, und wobei die beiden Klemmbacken (131) jeweils mit einem Durchgangsloch (135) versehen sind; und einem Befestigungselement (14), das durch die Durchgangslöcher (135) der beiden Klemmbacken (131) hindurchgeführt wird.
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Sterilisationsvorrichtung zur Verbesserung der Desinfektionswirkung, umfassend: einen Hauptkörper, der eine erste Oberfläche, eine von der ersten Oberfläche abgewandte zweite Oberfläche und ein Aufnahmeloch aufweist, wobei die zwei Seiten des Hauptkörpers jeweils mit einem Durchgangsloch versehen sind, wobei die Durchgangslöcher mit dem Aufnahmeloch durchgängig verbunden sind; eine Desinfektionslampe, die auf der zweiten Oberfläche des Hauptkörpers angeordnet ist und eine Lichtemissionseinheit, eine Erfassungseinheit, eine Steuereinheit und eine Stromversorgungseinheit umfasst; und ein Befestigungsteil, das durch die Durchgangslöcher und das Aufnahmeloch des Hauptkörpers hindurchgeführt ist.
IMPROVEMENTS RELATED TO PARTICLE, INCLUDING SARS-CoV-2, DETECTION AND METHODS THEREFOR - - link
DEEP LEARNING BASED SYSTEM FOR DETECTION OF COVID-19 DISEASE OF PATIENT AT INFECTION RISK - The present invention relates to Deep learning based system for detection of covid-19 disease of patient at infection risk. The objective of the present invention is to solve the problems in the prior art related to technologies of detection of covid-19 disease using CT scan image processing. - link
Netanyahu’s Likely Departure Is Not Easing the Fears of Palestinians - Attacks by settlers in the West Bank have been on the rise for years—and a new Israeli government is no guarantee of change. - link
Is There Any Time Left for Maya Wiley? - The former City Hall lawyer, who has received the endorsement of Alexandria Ocasio-Cortez, considers herself the last progressive standing in New York’s mayoral race. - link
The Importance of Teaching Dred Scott - By limiting discussion of the infamous Supreme Court decision, law-school professors risk minimizing the role of racism in American history. - link
The Defeat of Benjamin Netanyahu - Israel’s longest-serving Prime Minister has dragged the country ever rightward, abandoning the peace process and imperilling its very democracy. - link
The Big Stakes and Deep Weirdness of the Last Days of New York City’s Mayoral Race - The future of the country’s largest city is on the line. This week, campaign reporting focussed on a candidate’s refrigerator. - link
+AppleTV+’s Mythic Quest is one of TV’s sneakiest comedies, funny and tragic all at once. +
++Poppy Li is one of my favorite characters in all of television. +
++Poppy, as played by Charlotte Nicdao, is one of the main characters of Mythic Quest, an AppleTV+ comedy set at a video game studio. The studio produces the massively multiplayer online role-playing game of the show’s title, and when the show begins, it is about to release a major expansion for the game named Raven’s Banquet. (In fact, season one is properly called Mythic Quest: Raven’s Banquet.) Much of that first season centers on the conflict between creative director Ian Grimm (Rob McElhenney), from whose brain Mythic Quest first sprung, and lead engineer Poppy, who has to make all of Ian’s dreams a reality. +
++(I just want to note here that Ian’s name is pronounced like the word “ion,” which is a perfect joke about his pretension and self-regard that slowly reveals itself to have more layers as the show goes on. That slow unfolding is kind of Mythic Quest’s whole deal.) +
++It would be so easy for Mythic Quest to make Poppy an underdog hero the audience can root for. She is perpetually overworked and underpraised, and as the series gets underway, she simply wants to program a shovel into the game so players can use it to dig stuff. Ian insists she make the shovel into a weapon, because if it’s only a shovel, the players will use it to dig dicks, plus it will be more exciting if players can use it to wail on people. Ian is right on both counts: They do dig dicks, and the shovel is way more satisfying as an implement of blunt force trauma. +
++Mythic Quest plays on everything you know about dramatic storytelling to make you think from that very first episode that it is a story about Ian slowly realizing Poppy’s genius and the two of them learning to trust and support each other. And the series sort of is that. But it’s never just that, especially when it comes to Poppy. +
++Nicdao plays Poppy like she’s a dandelion fighting against her very self to let all her seeds blow away. She maybe should let go of some stuff, but she takes on more and more until it’s too much. She is constantly grabbing hold of new tasks and challenges while also trying to keep an eye on the old ones, and she sometimes seems like the only person working on the game of Mythic Quest who is capable of actually doing her job. There’s a just-subtle-enough throughline about how Poppy would earn more recognition for her achievements if she were a man, and how being a woman who works in video games means always working harder and harder and harder to remain only one step behind male colleagues who aren’t as talented. +
++Yet Poppy is so much more than a commentary on being a woman in a male-dominated field. She’s also a fairly savage satire of girlboss feminism and its propensity to turn the people who practice it into narcissists who only look out for themselves. The easiest way to make Poppy crumple and do what you want is to call her a genius, so intent is she on getting people to understand how great she is. Poppy is so constantly focused on catching up to Ian that she doesn’t see all of the people she’s stepping on along the way. +
++In Mythic Quest’s season two premiere, for instance, she corrals two of the handful of other women on staff for a little gossip and girl talk, then threatens to fire them if they spill her secrets. The show plays the scene for laughs, to be sure, but it’s always aware of the razor-thin line it walks between making Poppy too much of a rah-rah underdog and too much of a boss from hell. She’s complicated and self-obsessed and very funny, and it’s telling just how aggressively the series pivoted to be about the unlikely creative rivalry/partnership between Poppy and Ian. It was already trending in that direction in season one; in season two, Poppy and Ian’s friction is the very core of the show. +
++Mythic Quest is a bit of an oddball show because, for most of its episodes, it’s a very funny workplace comedy with a killer ensemble cast and a surprising amount of heart. (If you watch it, you will not be surprised when I tell you that co-creator Megan Ganz cut her teeth on Community.) But then, every so often, the series will abruptly become one of TV’s most moving dramas about the impossibility of creating art that can match up to the vision in one’s own head, because of market forces, personal failings, or both. The episodes that confront this impossibility largely stand outside of Mythic Quest’s narrative, commenting on it only obliquely. But they always tie into the show’s thematic core. +
++These more dramatic episodes often become Mythic Quest’s most hyped element — the season two standalone, for instance, garnered probably the most media coverage the series has received in its second season. But that level of attention has also somewhat distorted the view of what Mythic Quest even is, which is a workplace comedy about navigating a world in which small and petty men call most of the shots. Ian is probably the genius his marketing materials make him out to be — he did create a pretty great video game — but he’s also just exhausting to work with. Many comedies would soften him, the better to make him slightly more cuddly. With only 20 episodes so far, Mythic Quest has humanized Ian without losing how annoying he is. That’s an impressive feat. +
++I have barely touched on the other elements that make Mythic Quest great, like Danny Pudi’s against-type work as a conniving asshole or the show’s frequently inventive visuals. (I will never get tired of little doors popping open in a giant mural of the video game’s characters — it stands multiple stories tall and serves as the flashy focal point of the office — to reveal one employee yelling down to another on the main floor to fetch them something.) Hell, the show has one of TV’s best romantic relationships between two women, and its rotating cast of recurring players is almost as good as its main ensemble. +
++Mostly, though, Mythic Quest struck me, again and again throughout its first two seasons, as a show about how difficult it is to make anything good, especially when ego stands in the way. But if you want to best someone with an inflated ego, often the only way to do so is to puff up your own ego until it’s larger, and then where does that leave you? Poppy’s on her way there, and I have no idea where she might end up. +
++Mythic Quest releases new season two episodes every Friday through June 25 on AppleTV+. The first season and most of the second are streaming already. +
++For more recommendations from the world of culture, check out the One Good Thing archives. +
++
++
+Merrick Garland’s speech is a cry for congressional action. +
++As Republican-controlled state legislatures around the country clamp down on the right to vote, the Biden Justice Department is preparing to push back — but its efforts, hampered by stalled federal voting rights legislation, may only be able to achieve so much. +
++In a speech on Friday, Attorney General Merrick Garland laid out the DOJ plan to protect voting rights and announced that the department’s Civil Rights Division would begin staffing up to aid enforcement efforts. +
++According to Garland, the voting section of the Civil Rights Division will double its staff of lawyers “within the next thirty days,” and the DOJ will renew its efforts to use existing laws, such as the Voting Rights Act of 1965, the National Voter Registration Act, and the Help America Vote Act, to “ensure that we protect every qualified American seeking to participate in our democracy.” +
++“There are many things that are open to debate in America,” Garland said Friday. “But the right of all eligible citizens to vote is not one of them. The right to vote is the cornerstone of our democracy, the right from which all other rights ultimately flow.” +
+++Attorney General Merrick Garland: “There are many things that are open to debate in America. But the right of all eligible citizens to vote is not one of them. The right to vote is the cornerstone of our democracy, the right from which all other rights ultimately flow.” pic.twitter.com/CweEfo3bVX +
+— CBS News (@CBSNews) June 11, 2021 +
+To protect that right, though, the department has its work cut out for it: already this year, at least 14 states, including swing states like Arizona, Florida, and Georgia, have imposed new voting restrictions, according to the Brennan Center for Justice, which tracks voting rights issues. +
++And last weekend, Texas Democrats narrowly (and possibly only temporarily) blocked an additional measure in the Lone Star State, which would have slashed early voting hours and limited mail-in voting in the state, among other changes, by walking out of the Texas Capitol to deny the state House a necessary quorum. +
++Garland said Friday that those new laws would be examined as part of the DOJ’s voting rights push, as would state-level election “audits” like the one currently underway in Arizona. +
++Additionally, the DOJ will take steps to address election disinformation, according to Garland, and it will publish new guidance on early voting, mail-in voting, and the upcoming redistricting process. +
++“Where we see violations, we will not hesitate to act,” Garland said. +
++Despite laying out a major effort to combat voter suppression and protect voting rights, however, Garland was also forthright on Friday about the DOJ’s limitations in the wake of the Supreme Court’s 2013 decision in Shelby County v. Holder, which struck down a key portion of the Voting Rights Act. +
++According to the Court’s ruling in Shelby, the preclearance formula used in the act — which defined which states and localities were subject to preclearance, or approval by the federal DOJ before changing their voting laws — was out-of-date and unconstitutional. +
++The result, as Jenée Desmond-Harris explained for Vox in 2016, is that “until Congress passes legislation with a new formula for preclearance under Section 4 — which doesn’t look likely to happen anytime soon — jurisdictions that were covered by the previous formula are free to make election changes without any need to get approval from the federal government.” +
++Prior to Shelby, nine states — Alabama, Alaska, Arizona, Georgia, Louisiana, Mississippi, South Carolina, Texas, and Virginia — were governed by the federal preclearance requirement, as were some areas in California, Florida, Michigan, New York, North Carolina, and South Dakota. +
++The pre-Shelby coverage formula that imposed preclearance requirements on those states mandated that any state or “political subdivision” within a state that both “maintained a ‘test or device’ restricting the opportunity to register and vote,” and had less than 50 percent of its voting-age population either registered to vote or voting in the 1964 presidential election would be subject to federal preclearance. +
++However, while the formula was updated over the years — for example, the iteration struck down by the Supreme Court relied on voter turnout and voter registration levels from 1972 instead — the Court ruled that: +
++++[A] statute’s “current burdens” must be justified by “current needs,” and any “disparate geographic coverage” must be “sufficiently related to the problem that it targets.” The coverage formula met that test in 1965, but no longer does so. Coverage today is based on decades-old data and eradicated practices. The formula captures States by reference to literacy tests and low voter registration and turnout in the 1960s and early 1970s. … In 1965, the States could be divided into two groups: those with a recent history of voting tests and low voter registration and turnout, and those without those characteristics. Congress based its coverage formula on that distinction. Today the Nation is no longer divided along those lines, yet the Voting Rights Act continues to treat it as if it were. +
+
+But approximately eight years after the Supreme Court’s decision, Congress still hasn’t provided a new formula for preclearance, and doesn’t look likely to do so anytime soon, since a renewal of the Voting Rights Act would require 60 votes in the Senate under current rules and, despite little Republican support for such a bill, Democratic Sens. Joe Manchin and Kyrsten Sinema continue to take a hard line against abolishing the filibuster. +
++What did happen in the interim, however, was a slew of new voting restrictions in states previously subject to preclearance — restrictions that may not have become law, were preclearance still in place. As P.R. Lockhart reported for Vox in 2019: +
++++According to the Brennan Center for Justice, a policy and research group that monitors new voting restrictions, there have been hundreds of “harsh measures making it harder to vote” introduced in state legislatures since 2010. Many of these were introduced after the 2013 Shelby ruling, and, as a federal commission noted last year, have been seen both in states previously subjected to preclearance and states that were not. +
++These restrictions have taken many forms, including strict photo ID requirements, limitations on who can provide assistance at polling places, the curbing of early voting days, and the closing of hundreds of polling places across the US. Other measures, like the purging of voters from state voter rolls and drawing election districts in a way that curbs the power of voters of color, have affected how much power communities of color hold in elections. +
+
+Similar measures have continued to pile up since then, particularly in the wake of former President Donald Trump’s 2020 election defeat and the widespread GOP adoption of baseless “election fraud” rhetoric. As Garland pointed out on Friday, that’s at least partially because of Shelby, which put an end to preclearance absent further congressional action. +
++++So my big takeaway from AG Garland’s speech on voting rights is that he might as well have said “I will use every single one of the wholly inadequate tools that I now have to protect democracy, FU SCOTUS.” +
+— Ian Millhiser (@imillhiser) June 11, 2021 +
+“Although we will not wait for that legislation to act, we must be clear-eyed,” Garland said Friday. “The Shelby County decision eliminated critical tools for protecting voting rights. And, as the President has said, we need Congress to pass S.1 and the John Lewis Voting Rights Act, which would provide the department with the tools it needs.” +
++Though the harm done by Shelby and the effective end of preclearance isn’t new, Garland’s speech Friday highlights why things are looking increasingly grim for voting rights in the US, despite the prospect of more DOJ enforcement of federal voting protections. +
++Specifically, as Vox’s Ian Millhiser explained earlier this month, the current GOP offensive against voting rights, animated by the Big Lie that has increasingly become an article of faith for the Republican Party, is all the more worrying because it is being advanced on multiple fronts, some far harder to overcome than others. +
++In addition to direct efforts to make it harder to vote — early voting restrictions, voter ID laws, and the like, none of which are new to the GOP — multiple Republican-controlled state legislatures have advanced efforts that could make it easier for the GOP to overturn elections on the basis of made-up claims of voter fraud. +
+ ++++Not every provision of the latest round of voter suppression bills can be overcome either by vigilant voters or by smart campaigns. +
++Georgia’s new law, for example, permits state-level Republican officials to take over local election boards in Democratic strongholds such as Atlanta. That matters because these local boards can potentially close polling places, disqualify voters, or even refuse to certify an election result. Voters who do everything right might nonetheless have their ballots disqualified. +
+
+What’s more, Georgia isn’t alone in attempting to shift power over elections to Republicans. In Arizona, Republican state legislators are pushing a measure to strip Democratic secretary of state Katie Hobbs of her power to defend election lawsuits. +
++The measure, which was advanced through committee late last month, would instead transfer that power to a Republican — and as the Washington Post’s Aaron Blake points out, appears specifically designed to target Hobbs and would expire when her term does. +
++That particular proposal hasn’t passed yet, and it’s unclear if it will — but Arizona Republicans, who are currently overseeing an “audit” of the the 2020 election results in Maricopa County, have been at the forefront of the GOP war against small-d democracy with measures like the one targeting Hobbs. +
++As political scientist David Faris explained to Vox’s Sean Illing in May, the new GOP strategy hinges on finding “a way to overturn an election with the veneer of legality” — and Faris says 2020 was only a “test run.” +
++“You have to give Trump and Republicans some kind of dark credit for figuring out that this is really conceivable,” Faris told Vox. “I think they now know that, even though it would cause a court battle and possibly a civil war, that if they can’t win by suppressing the vote and the election is close enough, they can do this if they control enough state legislatures and the Congress.” +
++As Garland said in his speech Friday, however, there are bills that could potentially stem the tide of GOP-led voter suppression and election subversion measures. Specifically, two Democratic proposals — the For the People Act and the John Lewis Voting Rights Act — would both make strides toward resurrecting and expanding federal voting rights protections. +
++++Same. But on this I don’t think it’s Garland’s fault that his office is not the one that is best positioned to defend voting rights. Article II is not where the power is at here.
+— Elie Mystal (@ElieNYC) June 11, 2021 +
Article I (Congress) and Article III (the Judiciary) are supposed to be doing this work. https://t.co/pnHMPjFnCw +
+The first of the pair, the For the People Act, would represent a sea change in federal voting protections if passed. +
++According to Vox’s Andrew Prokop, the bill “would require automatic voter registration, same-day registration, and at least two weeks of early voting” in all federal elections, and it would “restore voting rights to all felons who have completed their terms of incarceration, allow registered voters lacking IDs to submit a sworn written statement instead, and attempt to limit voter roll purges,” among a slew of other changes. +
++It would also establish nonpartisan redistricting commissions to end partisan gerrymandering, create new anti-corruption measures, and quite a bit more. +
++However, it’s likely dead in the water after Manchin came out against it in an op-ed last week, even setting aside the fact that it lacks Republican support and thus couldn’t clear the 60-vote threshold imposed by the filibuster (which, again, Manchin does support). +
++That leaves the John Lewis Voting Rights Act, which would give the DOJ back what Garland called its “most effective tool to protect voting rights over the past half-century” — preclearance. +
++++AG Merrick Garland wraps up his speech on voting rights by quoting the late John Lewis: “Democracy is not a state. It is an act. And each generation much do its part.” pic.twitter.com/gCMpLhTltk +
+— Aaron Rupar (@atrupar) June 11, 2021 +
+According to New York magazine’s Ed Kilgore, Manchin has even proposed a version of the bill that would go farther than the formula struck down by the Supreme Court in 2013 and expand preclearance to all 50 states, though it wouldn’t impact voting laws like the one already on the books in Georgia. +
++++IMO, Democrats’ first priority now should be convincing Manchin that the John Lewis Voting Rights Act should also contain strong non-partisan redistricting rules +
+— Zack Beauchamp (@zackbeauchamp) June 7, 2021 +
+Still, a renewal of the Voting Rights Act, like the For the People Act, would be subject to the filibuster, which doesn’t put it in much better shape as far as prospects in the Senate go. Since Manchin is on the record as supporting it, and it has at least one Republican backer in Alaska Sen. Lisa Murkowski, it’s a slightly cheerier picture — but if Manchin and Sinema don’t budge on the filibuster, and they don’t seem inclined to so far, it won’t matter. +
++As a result, even as the DOJ prepares to step up its voting protection efforts, it’s somewhat unclear what comes next in the struggle over voting rights. As Washington Post columnist and former FiveThirtyEight elections reporter Perry Bacon Jr. wrote last month, “America is still headed in a terrible direction — and at a much faster pace than I expected when Biden took over.” +
++“Moderate Democrats and anti-Trump Republicans either don’t appreciate the direness of the situation or don’t care,” Bacon argues. “I hope I am overly alarmed about all of this. But I don’t think I am. Perhaps democracy dies faster in darkness. But it could also die slowly in the light, as all of us watched but didn’t do enough to save it.” +
++How Netanyahu’s ouster could change Israel. +
++Benjamin “Bibi” Netanyahu is Israel’s longest-serving prime minister, having held the job continuously since 2009. Now, finally, the reign of “King Bibi” — a moniker earned by his lengthy stay in office and authoritarian inclinations — has come to an end. +
++On Sunday, Netanyahu’s opponents in the Knesset, Israel’s parliament, voted to replace him with a “change” coalition: a group of diverse parties from across the Israeli political spectrum united only by their interest in pushing Netanyahu out. The new prime minister is Naftali Bennett, from the far-right Yamina party — though Yair Lapid, from the centrist Yesh Atid party, will have a veto over his decisions. +
++Netanyahu’s downfall is, more than anything else, the result of his own hubris. +
++Over the past 12 years, Netanyahu has dominated Israeli politics. He’s not only successfully implemented a series of right-wing policies, such as entrenching Israel’s presence in the West Bank, but also consolidated a dangerous amount of power in his own hands. He is currently on trial for corruption charges stemming from, among other things, his attempt to buy off media outlets. +
++Israeli politics has divided into pro- and anti-Bibi camps; the split is so narrow that Israel has been forced to hold four elections in two years, with none delivering a decisive verdict. +
++It’s this paralysis, and the looming threat of Netanyahu’s anti-democratic behavior, that brought parties from across the political spectrum together to finally get beyond him. +
++Bennett will serve as prime minister first, for two years, with Lapid taking over from him after that. It’s a power split that partly reflects the internal divisions inside the coalition, which depends on votes from eight different parties on the right, center, and left. One of the eight is Ra’am, an Islamist party and the first Arab party ever to join an Israeli governing coalition. +
+ ++Calling this arrangement unstable is an understatement. The members of this coalition agree on almost nothing and thus will be unable to make major policy changes on most issues without collapsing. This is especially true in the conflict with the Palestinians, where the divides among the coalition parties are arguably most severe. A major event, like another flare-up in Hamas rocket fire, could bring them to each others’ throats — forcing yet another round of elections. +
++But the fact that this new government exists at all speaks to the desire among many Israelis to move on from the Netanyahu era — a desire that led to a seismic change to Israeli politics. +
++“Simply replacing Netanyahu is a huge deal,” said Michael Koplow, the policy director at the US-based Israel Policy Forum think tank. “And including an Arab party in a government is a huge deal, even if the coalition falls apart after six months.” +
++For 10 years, from 2009 to 2019, Netanyahu rode the long-running rightward drift of the Israeli electorate to victory — defeating his opponents on the center and left through a mix of deft political strategy and demagoguery. But things started to fall apart after Israel’s election in April 2019, when the current political crisis began. +
++In that vote, Netanyahu’s Likud and allied right-wing parties won a majority of seats in the Knesset, seemingly setting them up for another extension of his historic premiership. But one party, the secular nationalist Yisrael Beiteinu, refused to join the government — citing a disagreement over special exemptions for mandatory military service given to ultra-Orthodox Jews. +
++The inability of Netanyahu or his opponents to form a government then led to another election in September of that year, which was supposed to resolve the deadlock. By then, Israeli politics had come to revolve around one big thing: Netanyahu himself and his alleged abuse of power while in office. +
++Bibi had served as prime minister once before, from 1996 to 1999. His defeat convinced him that he needed to make Israeli society more pliant to him personally — specifically, by bending the press to his will: “I need my own media,” as he put it at the time. +
++After his return to the top job, he seems to have tried to turn this proposal into action, allegedly attempting to trade political and regulatory favors for favorable coverage in two other outlets, the leading daily newspaper Yedioth Ahronoth (Latest News) and the popular online portal Walla! News. He seems to have succeeded with Walla, allegedly reaching a secret deal to approve a merger that its parent company wanted in exchange for slanting the news in his direction. +
++The head of government attempting to suborn the independent media by handing out favors is not only undemocratic, but also quite possibly illegal. Israel’s attorney general, the conservative Avichai Mandelblit, announced in February 2019 that he would seek to indict the prime minister on a series of corruption and bribery-related charges — including ones that carried up to 10 years of jail time. +
++By the time of the second election in September 2019, Netanyahu’s maneuvering to avoid prosecution had become increasingly dangerous to Israeli democracy. His allies in the Likud party had already proposed a law that would grant Netanyahu immunity from prosecution while in office, allowing him to get away with what looks like an assault on democratic institutions. +
++The September election was inconclusive: Netanyahu did not have enough support to hold office, but the opposition was too internally divided to form any kind of government. A third election, held in March 2020, had similar results. The outcome was a temporary unity government, designed primarily to respond to the coronavirus outbreak while sidelining the issue of Bibi’s prosecution. +
++Netanyahu blew up this fragile agreement in December, gambling that a fourth election would get him enough votes to form a more stable right-wing government. But he failed: That election, held in March, yielded the current Knesset. +
+ ++This time around, Netanyahu’s opponents decided enough was enough: Two years of chaos and elections needed to come to an end. +
++Lapid, whose Yesh Atid party won the most votes of any in the anti-Netanyahu camp, made a series of agreements with parties across the political spectrum to form the new coalition. This included not only Netanyahu’s longstanding opponents on the left and center, but also right-wing leaders who had previously been either ministers in Netanyahu’s cabinet or members of his own party. +
++The thing bringing these factions together is their shared belief that the chaos of the last two years must end. The only way to do that, they reasoned, is to take Netanyahu out of the top job. +
++“Netanyahu will not be able to get a majority [in a fifth election] and then we will go to a sixth election,” Bennett, the leader of Yamina, said during coalition discussions. “The country can’t continue like that.” +
++And now, as a result, Netanyahu has lost the top job — and will be forced to deal with his currently ongoing criminal trial without the power of the premiership. +
++Now, Bennett will serve as prime minister — a job he’ll keep for two years while Lapid serves as foreign minister. After two years, they will rotate, with Lapid taking the top position and Bennett in the cabinet. During the whole period, both of them will have veto power over policy — so even while Bennett is nominally Lapid’s boss, the latter will be able to block the former’s moves at will. +
++This complex power-sharing agreement is necessary to address the disagreements between these two men in particular and the coalition parties in general. In most of the key policy areas facing Israel, this government will be unable to agree on significant changes. +
++Take what’s arguably the country’s most important issue: the conflict with the Palestinians. On this, Bennett and Lapid have divergent views. Bennett supports annexing much of the West Bank and opposes the creation of a Palestinian state, while Lapid supports a two-state solution negotiated with the Palestinian leadership. The broader coalition is similarly divided, containing both hawkish factions like Yisrael Beiteinu and dovish ones like Meretz. +
++Any major actions on the Palestinians, in either an aggressive or conciliatory direction, would divide the change coalition bitterly. The most likely result is that, as long as this government is in power, the conflict will basically remain stuck in its abysmal status quo. +
++“If [the coalition] stays together, then it will necessarily mean inertia on the issues that affect Palestinians,” says Khaled Elgindy, director of the program on Palestine and Palestinian-Israeli affairs at the Middle East Institute. “Occupation, settlements, evictions, demolitions, [and the] Gaza blockade continue as they are.” +
++This is the case on a series of key issues that divide the Israeli left and right, like whether Israel’s courts have gone too far in protecting individual rights. Such controversial topics will, in general, remain untouched by the change coalition — tinkered with at the edges, perhaps, but unaffected in any large way. +
++“The limits on any contentious action are real. In some ways their mandate will be to just govern,” says Natan Sachs, director of the Center for Middle East Policy at the Brookings Institution. +
+ ++Nonetheless, there are some exceptions to this rule — areas where the new government could actually make a difference. +
++First, there’s the area that prompted Yisrael Beiteinu to break with Netanyahu all the way back in April 2019: the relationship between synagogue and state. +
++In the past, Israel’s ultra-Orthodox parties have been willing to throw their lot in with governments on both the left and the right so long as the government preserves their privileged status in Israeli law. But in the current standoff, the ultra-Orthodox parties chose to back Netanyahu — and now, as a result, are locked out of power. The right-wing parties in the current coalition are, by the standards of the Israeli right, relatively secular. +
++Judy Maltz, a reporter at the Israeli newspaper Haaretz, suggests there are still constraints in this area: Both Yamina and Ra’am, the Islamist party, will block some moves toward a more secular society. But at the same time, there are some areas — including reductions in special funding for the ultra-Orthodox, support for public transit on Shabbat, and non-Orthodox prayer at the Western Wall — where policy change is possible. +
++Second, there might also be some ability to improve the status of Palestinian citizens of Israel (also known as Arab Israelis). The very fact that one of this group’s leaders is in government for the first time — sharing power with right-wing politicians with a history of anti-Arab agitation — is a testament to the rising influence and growing legitimacy that Arab Israelis have in the Jewish-dominated political mainstream. +
++To keep Ra’am happy, the new coalition will need to provide concrete accomplishments that its members can show to its long-marginalized constituents. The party’s leader, Mansour Abbas, has already demanded more funding for infrastructure in Arab communities and an end to building codes that disadvantage Arabs — but there’s much more the coalition could do. +
++One of the top issues for Arab Israelis is a surge in Arab organized crime that has led to a murder epidemic; in 2019, 71 percent of Israeli murder victims were Arab, despite Palestinian citizens making up only 21 percent of the Israeli population. The Netanyahu government failed to adequately address this problem with police resources; perhaps, the new one will. +
++Finally, and perhaps most importantly, the change in government opens up prospects for political change. +
++For 20 years, the political right has dominated Israeli politics. Right-wing dominance empowered Netanyahu to both deepen the occupation of the West Bank and assault democracy inside Israel’s borders — two trends that are closely related. +
++Dethroning Netanyahu won’t put a stop to the occupation, nor will it entirely stop Israel’s slide away from democracy. But by ending Netanyahu’s chokehold on Israeli politics, it will create the possibilities for a move beyond the political status quo. Dahlia Scheindlin, an Israeli political strategist and fellow at the Century Foundation, puts the point well in a piece for the Guardian: +
++++Part of Netanyahu’s staying power has been the snowball effect of consolidating power. Voters cannot imagine anyone else governing, hence the oft-heard refrain “There’s no one else but him”. A new government would demonstrate that there is. If the rotation for prime minister goes as planned, from Bennett to Lapid, citizens will see that there are even two someone elses. That’s healthy for democracy. +
+
+Of course, it’s also possible that things go the other way. Once Netanyahu is out of the picture, perhaps even in jail, his Likud party will be free to join with the right-wing members of the coalition and the religious parties in a far-right coalition. +
++But that’s the nature of change: It’s unpredictable. Whether it ends up being for better or for worse in the long run is hard to say, but what’s clear is that some kind of change is finally coming to Israeli politics. +
++“I’m not optimistic about Israel, ever,” says Hadas Aron, a professor at New York University who studies Israeli politics. “But I do think it’s not meaningless that someone else will be in government, that something else could at least have the potential to rise.” +
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Covid: Lockdown easing in England to be delayed by four weeks - Most current Covid rules will remain for four more weeks after 21 June, government sources say.
Swiss voters reject key climate change measures - In a shock result, voters narrowly reject a tax on flights and a fuel levy among other policies.
Madrid protests: Thousands rally against Catalan pardons - Right-wing Spanish parties say plans to pardon separatist leaders are a threat to national unity.
The Ars Technica Father’s Day 2021 gift guide - We give a few gifting prompts for the guy who won’t say what he actually wants. - link
16 games to keep an eye on from Sunday’s E3 2021 trailer showcases - From shooters to puzzles to mail delivery sims, these concepts stood out from the crowd. - link
Raiders of the Lost Ark turns 40, and it’s still an unqualified masterpiece - Paramount released 4K Blu-Ray collection of first 4 films to mark the occasion. - link
Every trailer and announcement from Microsoft and Bethesda’s E3 showcase - Halo! Forza! Psychonauts! Age of Empires! And dozens of other games, too! - link
Ticket for space flight with Jeff Bezos is auctioned for $28 million - Unnamed passenger will pay more than $9 million per minute of zero gravity. - link
+And that’s how I lost my job at the orphanage. +
+ submitted by /u/SleazySerpent1469
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+She says to her husband, ‘see that drunk, I turned down his proposal 10 years ago. Husband looks at his wife, looks at the guy and sighs, ‘that explains why he is still celebrating’ +
+ submitted by /u/dr1ll37
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+The drug dealer can’t wash the crack and resell it +
+ submitted by /u/ertdgaf
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+“Both my wife and I have black hair, but our son’s just been born with red hair. Do you think something funny has been going on?” +
++“Not necessarily,” replied the doctor. “How many times do you have sex?” +
++“About 5 times a year.” +
++“Well, there’s your answer then, you’re just a little rusty.” +
+ submitted by /u/purple-circle
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+With an ithberg +
+ submitted by /u/Popular-Salamander-6
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